JP2002514919A - 多価ライブラリーおよびポリクローナルライブラリー - Google Patents

多価ライブラリーおよびポリクローナルライブラリー

Info

Publication number
JP2002514919A
JP2002514919A JP54607598A JP54607598A JP2002514919A JP 2002514919 A JP2002514919 A JP 2002514919A JP 54607598 A JP54607598 A JP 54607598A JP 54607598 A JP54607598 A JP 54607598A JP 2002514919 A JP2002514919 A JP 2002514919A
Authority
JP
Japan
Prior art keywords
library
antibody
phage
polypeptide
members
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP54607598A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002514919A5 (enExample
Inventor
グレイ，ジェフ
ブークラー，ジョー
バルカーズ，ガナース
Original Assignee
バイオサイト ダイアグノスティックス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/835,159 external-priority patent/US6555310B1/en
Priority claimed from US08/832,985 external-priority patent/US6057098A/en
Application filed by バイオサイト ダイアグノスティックス，インコーポレイテッド filed Critical バイオサイト ダイアグノスティックス，インコーポレイテッド
Publication of JP2002514919A publication Critical patent/JP2002514919A/ja
Publication of JP2002514919A5 publication Critical patent/JP2002514919A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP54607598A 1997-04-04 1998-04-03 多価ライブラリーおよびポリクローナルライブラリー Ceased JP2002514919A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/835,159 US6555310B1 (en) 1997-04-04 1997-04-04 Polyclonal libraries
US08/835,159 1997-04-04
US08/832,985 US6057098A (en) 1997-04-04 1997-04-04 Polyvalent display libraries
US08/832,985 1997-04-04
PCT/US1998/006704 WO1998047343A2 (en) 1997-04-04 1998-04-03 Antibodies or binding protein libraries displayed on phage, cells, or other replicatable genetic packages

Publications (2)

Publication Number Publication Date
JP2002514919A true JP2002514919A (ja) 2002-05-21
JP2002514919A5 JP2002514919A5 (enExample) 2005-11-24

Family

ID=27125574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54607598A Ceased JP2002514919A (ja) 1997-04-04 1998-04-03 多価ライブラリーおよびポリクローナルライブラリー

Country Status (5)

Country Link
US (3) US6420113B1 (enExample)
EP (1) EP0985033A4 (enExample)
JP (1) JP2002514919A (enExample)
AU (1) AU8755798A (enExample)
WO (1) WO1998047343A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013511268A (ja) * 2009-11-18 2013-04-04 ピエール、ファーブル、メディカマン 新規なファージディスプレイベクター

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Also Published As

Publication number Publication date
WO1998047343A2 (en) 1998-10-29
AU8755798A (en) 1998-11-13
WO1998047343A3 (en) 1998-12-10
US20050158796A1 (en) 2005-07-21
EP0985033A2 (en) 2000-03-15
US20030104477A1 (en) 2003-06-05
WO1998047343A9 (en) 1999-04-15
EP0985033A4 (en) 2005-07-13
US6420113B1 (en) 2002-07-16

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