JP2002514184A5 - - Google Patents

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Publication number
JP2002514184A5
JP2002514184A5 JP1998515635A JP51563598A JP2002514184A5 JP 2002514184 A5 JP2002514184 A5 JP 2002514184A5 JP 1998515635 A JP1998515635 A JP 1998515635A JP 51563598 A JP51563598 A JP 51563598A JP 2002514184 A5 JP2002514184 A5 JP 2002514184A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998515635A
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English (en)
Japanese (ja)
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JP2002514184A (ja
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Publication date
Priority claimed from US08/718,703 external-priority patent/US5824662A/en
Priority claimed from US08/842,360 external-priority patent/US6054444A/en
Priority claimed from US08/863,624 external-priority patent/US6046180A/en
Priority claimed from US08/858,985 external-priority patent/US6025344A/en
Priority claimed from US08/884,479 external-priority patent/US6017903A/en
Application filed filed Critical
Priority claimed from PCT/US1997/014344 external-priority patent/WO1998013046A1/en
Publication of JP2002514184A publication Critical patent/JP2002514184A/ja
Publication of JP2002514184A5 publication Critical patent/JP2002514184A5/ja
Ceased legal-status Critical Current

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JP51563598A 1996-09-27 1997-08-15 Naaladアーゼ組成物ならびに動物におけるグルタメート異常を治療する方法および神経活性をもたらす方法 Ceased JP2002514184A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US08/718,703 1996-09-27
US08/718,703 US5824662A (en) 1996-09-27 1996-09-27 Treatment of global and focal ischemia using naaladase inhibitors
US08/842,360 US6054444A (en) 1997-04-24 1997-04-24 Phosphonic acid derivatives
US08/842,360 1997-04-24
US08/858,985 1997-05-27
US08/863,624 US6046180A (en) 1996-06-17 1997-05-27 NAALADase inhibitors
US08/858,985 US6025344A (en) 1996-06-17 1997-05-27 Certain dioic acid derivatives useful as NAALADase inhibitors
US08/884,479 1997-06-27
US08/884,479 US6017903A (en) 1996-09-27 1997-06-27 Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US08/863,624 1997-07-25
PCT/US1997/014344 WO1998013046A1 (en) 1996-09-27 1997-08-15 Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals

Publications (2)

Publication Number Publication Date
JP2002514184A JP2002514184A (ja) 2002-05-14
JP2002514184A5 true JP2002514184A5 (enExample) 2005-04-07

Family

ID=27542138

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51563598A Ceased JP2002514184A (ja) 1996-09-27 1997-08-15 Naaladアーゼ組成物ならびに動物におけるグルタメート異常を治療する方法および神経活性をもたらす方法

Country Status (16)

Country Link
US (1) US6413948B1 (enExample)
EP (1) EP1005348A1 (enExample)
JP (1) JP2002514184A (enExample)
KR (1) KR20000036227A (enExample)
CN (1) CN1230889A (enExample)
AU (1) AU733880B2 (enExample)
CA (1) CA2264043A1 (enExample)
CZ (1) CZ60499A3 (enExample)
HU (1) HUP0001062A3 (enExample)
IL (1) IL128718A0 (enExample)
LV (1) LV12283A (enExample)
NO (1) NO991387L (enExample)
NZ (1) NZ334780A (enExample)
PL (1) PL332413A1 (enExample)
TR (1) TR199901173T2 (enExample)
WO (1) WO1998013046A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6953668B1 (en) 1992-11-05 2005-10-11 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
US7070782B1 (en) * 1992-11-05 2006-07-04 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen
US7105159B1 (en) 1992-11-05 2006-09-12 Sloan-Kettering Institute For Cancer Research Antibodies to prostate-specific membrane antigen
US6569432B1 (en) * 1995-02-24 2003-05-27 Sloan-Kettering Institute For Cancer Research Prostate-specific membrane antigen and uses thereof
JP2001526522A (ja) 1995-02-24 2001-12-18 スローン−ケタリング・インスティテュート・フォー・キャンサー・リサーチ 前立腺特異的膜抗原およびその使用
US20040253246A1 (en) * 1996-02-23 2004-12-16 Israeli Ron S. Prostate-specific membrane antigen and uses thereof
US6071965A (en) * 1996-06-17 2000-06-06 Guilford Pharmaceuticals Inc. Phosphinic alkanoic acid derivatives
ID20347A (id) * 1997-05-27 1998-12-03 Guilford Pharm Inc Inhibitor aktifitas enzim naaladase
US6159958A (en) * 1997-08-14 2000-12-12 The United States Of America As Represented By The Secretary Of The Army Treatment or prophylaxis of retinal pathology and spinal cord injury
NZ550116A (en) * 1997-08-18 2008-03-28 Neurochem Int Ltd Phosphono-carboxylate compounds for treating amyloidosis
AU3822902A (en) * 1997-08-18 2002-06-27 Queen's University At Kingston Phosphono-carboxylate compounds for treating amyloidosis
US6329356B1 (en) 1998-04-10 2001-12-11 Neurochem, Inc. Phosphono-carboxylate compounds for treating amyloidosis
US6444657B1 (en) * 1998-12-31 2002-09-03 Guilford Pharmaceuticals Inc. Methods for treating certain diseases using naaladase inhibitors
US6528499B1 (en) 2000-04-27 2003-03-04 Georgetown University Ligands for metabotropic glutamate receptors and inhibitors of NAALADase
AU773915B2 (en) 1999-04-28 2004-06-10 Georgetown University Ligands for metabotropic glutamate receptors
US6562836B1 (en) 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
US6228888B1 (en) * 1999-07-01 2001-05-08 Guilford Pharmaceuticals Inc. Methods for treating anxiety, anxiety disorders and memory impairment using naaladase inhibitors
US6627625B1 (en) 1999-08-16 2003-09-30 Revaax Pharmaceuticals, Llc Treatment of behavioral disorders with β-lactam compounds
AU2001265111A1 (en) * 2000-05-30 2001-12-11 Guilford Pharmaceuticals Inc. Benzenedicarboxylic acid derivatives
US20020013295A1 (en) * 2000-05-30 2002-01-31 Slusher Barbara S. Naaladase inhibitors for treating amyotrophic lateral sclerosis
JP2005507857A (ja) 2001-02-07 2005-03-24 ベズ イズレイル ディーコネス メディカル センター 改変psmaリガンド及びそれに関する利用
EP2360169B1 (en) 2001-10-23 2015-10-14 Psma Development Company, L.L.C. PSMA antibodies
US20050215472A1 (en) 2001-10-23 2005-09-29 Psma Development Company, Llc PSMA formulations and uses thereof
AU2002357003A1 (en) * 2001-12-28 2003-07-24 Guilford Pharmaceuticals Inc. Indoles as naaladase inhibitors
SI1599461T1 (sl) * 2003-03-03 2009-10-31 Eisai Corp Of North Amarica Tiolaktoni kot inhibitorji NAALADaze
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
KR101242962B1 (ko) 2004-09-17 2013-03-13 아이데닉스 파마슈티칼스, 인코포레이티드 Hiv 억제제로서의 포스포인돌
BRPI0519243A2 (pt) 2004-12-22 2009-01-06 Neurochem Int Ltd mÉtodos e composiÇÕes para tratar doenÇas relacionadas a amilàide
CA2609980C (en) * 2005-05-27 2015-10-13 Queen's University At Kingston Treatment of protein folding disorders
NZ575831A (en) 2006-09-29 2011-12-22 Idenix Pharmaceuticals Inc Enantiomerically pure phosphoindoles as hiv inhibitors
MX339684B (es) 2006-10-12 2016-06-06 Bhi Ltd Partnership Metodos, compuestos, composiciones y vehiculos para suministrar el acido 3-amino-1-propanosulfonico.
EP3699162B1 (en) 2006-11-08 2022-06-29 Molecular Insight Pharmaceuticals, Inc. Heterodimers of glutamic acid
WO2010065899A2 (en) 2008-12-05 2010-06-10 Molecular Insight Pharmaceuticals, Inc. Technetium-and rhenium-bis(heteroaryl)complexes and methods of use thereof
AU2010260195B2 (en) 2009-06-15 2014-11-20 Molecular Insight Pharmaceuticals, Inc. Process for production of heterodimers of glutamic acid
US9737552B2 (en) 2010-12-14 2017-08-22 The Johns Hopkins University Treatment of cognitive impairment in a subject with a neurological autoimmune disease
EP2800471A4 (en) 2012-01-06 2015-11-04 Molecular Insight Pharm Inc METAL COMPLEX OF POLY (CARBOXYL) AMINE CONTAINING LIGANDS HAVING AFFINITY FOR CARBON IX ANHYDRASE
ES2648096T3 (es) 2013-01-14 2017-12-28 Molecular Insight Pharmaceuticals, Inc. Radiofármacos a base de triazina y agentes de radioformación de imágenes

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156840A (en) 1982-03-09 1992-10-20 Cytogen Corporation Amine-containing porphyrin derivatives
US4671958A (en) 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US5140104A (en) 1982-03-09 1992-08-18 Cytogen Corporation Amine derivatives of folic acid analogs
US4950738A (en) 1984-09-13 1990-08-21 Cytogen Corporation Amine derivatives of anthracycline antibiotics
US5162512A (en) 1982-03-09 1992-11-10 Cytogen Corporation Amine derivatives of anthracycline antibodies
US4867973A (en) 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
FR2590674B1 (fr) 1985-11-25 1989-03-03 Inst Nat Sante Rech Med Nouveaux reactifs de diagnostic
US5093525A (en) 1986-07-10 1992-03-03 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists
US4906779A (en) 1986-07-10 1990-03-06 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists
US5190976A (en) 1986-07-10 1993-03-02 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And University Of Oregon N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists
JP2608550B2 (ja) * 1986-10-17 1997-05-07 株式会社 片山化学工業研究所 軟水ボイラの防食処理方法
US5143908A (en) * 1986-11-05 1992-09-01 Merck & Co., Inc. Antibacterial agents and potentiators of carbapenem antibiotics
US4806543A (en) 1986-11-25 1989-02-21 Board Of Trustees Of The Leland Stanford Junior University Method and compositions for reducing neurotoxic injury
CA1305177C (en) 1987-06-30 1992-07-14 Yasufumi Ohfune Carboxycyclopropylglycine and process for producing the same
US4918064A (en) 1987-10-21 1990-04-17 G. D. Searle & Co. Phenyl glycines for use in reducing neurotoxic injury
US5871472A (en) 1987-11-17 1999-02-16 Brown University Research Foundation Planting devices for the focal release of neuroinhibitory compounds
US5196439A (en) 1987-11-27 1993-03-23 Eisai Co., Ltd. Piperidine compounds useful to treat cerebrovascular diseases
ATE133942T1 (de) 1987-11-27 1996-02-15 Eisai Co Ltd Cyclische amine und pharmakologische verbindungen
US4937183A (en) 1988-02-03 1990-06-26 Cytogen Corporation Method for the preparation of antibody-fragment conjugates
US5047227A (en) 1988-02-08 1991-09-10 Cytogen Corporation Novel and improved antibodies for site specific attachment of compounds
ES2061782T3 (es) 1988-05-16 1994-12-16 Searle & Co Compuestos de acido 2-amino-4,5-metilenadipico para el tratamiento de trastornos del snc.
IT1217603B (it) 1988-05-16 1990-03-30 Uni Degli Studi Perugia Derivati di acido 2 ammino 4,5 metilen adipico attivi sul sistema nervoso centrale
US5177109A (en) 1988-05-16 1993-01-05 G. D. Searle & Co. 2-amino-4,5-methyleneadipic acid compounds for treatment of CNS disorders
US5162504A (en) 1988-06-03 1992-11-10 Cytogen Corporation Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients
US4966999A (en) 1988-06-07 1990-10-30 Cytogen Corporation Radiohalogenated compounds for site specific labeling
DK160941C (da) 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
FI93838C (fi) 1988-06-28 1995-06-12 Novo Nordisk As Menetelmä uusien terapeuttisesti käyttökelpoisten 7,8-dihydroksi-1H-imidatso- ja pyratsolo/3,4-f/kinoksaliinijohdannaisten valmistamiseksi
DE3839659A1 (de) 1988-11-24 1990-05-31 Boehringer Ingelheim Kg Verwendung von benzomorphanen zur zytoprotektion
ES2052954T3 (es) 1988-12-15 1994-07-16 Rhone Poulenc Sante Derivados de imino-2-polifluoroalcoxi-6-benzotiazol, sus procedimientos de preparacion y los medicamentos que les contienen.
FR2649705B2 (fr) 1989-07-13 1994-09-23 Rhone Poulenc Sante Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
FR2649701B2 (fr) 1988-12-15 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR2640622B1 (fr) 1988-12-15 1991-03-22 Rhone Poulenc Sante Derives de l'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR2640624B1 (fr) 1988-12-15 1994-08-12 Rhone Poulenc Sante Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
US5236940A (en) 1988-12-15 1993-08-17 Rhone-Poulenc Sante Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation
FR2649703B1 (fr) 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 polyfluoroalcoxy-6 benzothiazole, leurs procedes de preparation et les medicaments les contenant
DE68901859T2 (de) 1988-12-15 1993-01-14 Rhone Poulenc Sante 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.
US5196510A (en) 1988-12-29 1993-03-23 Cytogen Corporation Molecular recognition units
US4994446A (en) 1989-01-03 1991-02-19 Ramot - University Authority For Applied Research And Industrial Development Ltd. Drug system
US5011834A (en) 1989-04-14 1991-04-30 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon PCP receptor ligands and the use thereof
FR2649702B1 (fr) 1989-07-13 1991-11-22 Rhone Poulenc Sante Derives d'alkylimino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
EP0497895A1 (en) 1989-10-25 1992-08-12 The Regents Of The University Of California Method of inhibiting the transport of l-glutamate
US5284867A (en) 1989-11-07 1994-02-08 Yissum Research Development Company Of The Hebrew University In Jerusalem NMDA-blocking pharmaceutical compositions
US5521215A (en) 1989-11-07 1996-05-28 Ramot University Authority For Applied Research And Industrial Development Ltd. NMDA-blocking pharmaceuticals
IL92238A (en) 1989-11-07 1995-07-31 Yissum Res Dev Co ADMN blocking product containing tetrahydrocannabinol history, several new tetrahydrocannabinol histories and process for their preparation
IT1238346B (it) 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
FR2662160B1 (fr) 1990-05-18 1992-07-24 Rhone Poulenc Sante Derives d'alkylthio-3 propyl-3 benzothiazoline leur preparation et les medicaments les contenant.
US5130330A (en) 1990-01-31 1992-07-14 G. D. Searle & Co. Nitrogen-containing cyclohetero cycloalkylaminoaryl derivatives for cns disorders
US5336689A (en) 1990-03-02 1994-08-09 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
US5262568A (en) 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
DK0517852T3 (da) 1990-03-02 2002-10-07 Oregon State Tri- og tetrasubstituerede guanidinerog disses anvendelse som excitatoriske aminosyre-antagonister
FR2662694A1 (fr) 1990-06-05 1991-12-06 Rhone Poulenc Sante Derives du benzoselenazole, leur preparation et les medicaments les contenant.
FR2662695A1 (fr) 1990-06-05 1991-12-06 Rhone Poulenc Sante Amino-2 polyfluoroalcoxy-6 benzoselenazoles, leur preparation et les medicaments les contenant.
FR2663029B1 (fr) 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
JPH0474197A (ja) 1990-07-12 1992-03-09 Naoyoshi Suzuki 新規な免疫調整生理活性ペプチド
US5089517A (en) 1990-08-03 1992-02-18 The Board Of Trustees Of The Leland Stanford Junior University Neuroprotection by indolactam v and derivatives thereof
US5145862A (en) 1990-08-16 1992-09-08 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method of resisting neurodegenerative disorders
WO1992004023A1 (en) 1990-09-10 1992-03-19 Shug Austin L Composition and method for protecting the heart during reperfusion
US5158976A (en) 1990-10-29 1992-10-27 The Children's Medical Center Corporation Controlling glutamine/glutamate related neuronal injury
ATE194985T1 (de) 1990-11-06 2000-08-15 Yamanouchi Pharma Co Ltd Kondensiertes pyrazinderivat
WO1992014697A1 (en) 1991-02-08 1992-09-03 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
US5135080A (en) 1991-04-30 1992-08-04 E. I. Du Pont De Nemours And Company Stand up fork lift truck safety net
JP2632754B2 (ja) 1991-05-21 1997-07-23 塩野義製薬株式会社 脳内グルタミン酸遊離抑制剤
FR2678619B1 (fr) 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
US5502166A (en) 1992-02-26 1996-03-26 Mitsubishi Chemical Corporation NMDH receptor proteins and genes encoding the same
US5326856A (en) 1992-04-09 1994-07-05 Cytogen Corporation Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
DE4212529A1 (de) 1992-04-10 1993-10-14 Schering Ag Verwendung von µ-Carbolinen als nicht-kompetitive Glutamat-Antagonisten
USH1312H (en) 1992-05-28 1994-05-03 Cytogen Corporation Method for the preparation of gyk-dtpa
WO1993025203A1 (en) 1992-06-17 1993-12-23 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo[a,d]cyclohepten-5,10-imine
IT1260156B (it) 1992-08-03 1996-03-28 Fidia Spa Derivati dell'acido neuraminico
US5489525A (en) 1992-10-08 1996-02-06 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies to prostate cells
DK0668777T3 (da) 1992-11-05 2007-02-19 Sloan Kettering Inst Cancer Prostataspecifikt membran-antigen
US5356902A (en) 1992-11-06 1994-10-18 Eli Lilly And Company Decahydroisoquinoline compounds as excitatory amino acid receptor antagonists
US5319095A (en) 1992-12-04 1994-06-07 Eli Lilly And Company Synthesis of kainic acid
US5438130A (en) 1993-01-15 1995-08-01 Cambridge Neuroscience, Inc. Fucosylated guanosine disulfates as excitatory amino acid antagonists
US5622965A (en) 1993-03-12 1997-04-22 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-ones and the use thereof as excitatory amino acid and glycine receptor antagonists
JP3209377B2 (ja) 1993-04-19 2001-09-17 花王株式会社 吸収性物品の製造方法
DK69693D0 (da) 1993-06-14 1993-06-14 Neurosearch As Farven lilla
FR2707880B1 (fr) 1993-06-30 1995-10-06 Rhone Poulenc Rorer Sa Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodégénératives.
US5434159A (en) 1993-09-14 1995-07-18 Sterling Winthrop Inc. 6,11-cyclyl-1,2,3,4,5,6,11,11a-octahydrobenzo[b]quinolines and compositions and method of use thereof
US5449761A (en) 1993-09-28 1995-09-12 Cytogen Corporation Metal-binding targeted polypeptide constructs
US5491241A (en) 1993-10-18 1996-02-13 Eli Lilly And Company Bicyclic intermediates for excitatory amino acid receptor antagonists
US5495042A (en) 1993-11-04 1996-02-27 Cytogen Corporation Non-alkaline purification of aminophosphonic acids
US5459037A (en) 1993-11-12 1995-10-17 The Scripps Research Institute Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
US5576323A (en) 1993-12-03 1996-11-19 Eli Lilly And Company Excitatory amino acid receptor antagonists
US5500420A (en) * 1993-12-20 1996-03-19 Cornell Research Foundation, Inc. Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia
US6274330B1 (en) 1993-12-30 2001-08-14 Zymogenetics, Inc. L-AP4 sensitive glutamate receptors
WO1995025110A1 (en) 1994-03-14 1995-09-21 Novo Nordisk A/S Heterocyclic compounds, their preparation and use
DE4410822A1 (de) 1994-03-24 1995-09-28 Schering Ag Neue Piperidin-Derivate
US5489717A (en) 1994-07-08 1996-02-06 Warner-Lambert Company Glutamate (NMDA) receptor antagonists
PL182285B1 (pl) 1994-08-12 2001-12-31 Lilly Co Eli Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL
US5661184A (en) 1994-08-12 1997-08-26 Eli Lilly And Company Psychiatric agents
TR199501070A2 (tr) 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevinin kristalli bicimi.
FR2726271B1 (fr) 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
US5473077A (en) 1994-11-14 1995-12-05 Eli Lilly And Company Pyrrolidinyl di-carboxylic acid derivatives as metabotropic glutamate receptor agonists
US5795877A (en) 1996-12-31 1998-08-18 Guilford Pharmaceuticals Inc. Inhibitors of NAALADase enzyme activity
US5804602A (en) 1996-06-17 1998-09-08 Guilford Pharmaceuticals Inc. Methods of cancer treatment using naaladase inhibitors
US5672592A (en) 1996-06-17 1997-09-30 Guilford Pharmaceuticals Inc. Certain phosphonomethyl-pentanedioic acid derivatives thereof
US5863536A (en) 1996-12-31 1999-01-26 Guilford Pharmaceuticals Inc. Phosphoramidate derivatives
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US5977090A (en) 1996-09-27 1999-11-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating compulsive disorders using NAALADase inhibitors
JP3170491B2 (ja) 1999-03-29 2001-05-28 松下電送システム株式会社 画像通信装置及びサーバ装置並びに能力交換方法
JP3762214B2 (ja) 2000-11-28 2006-04-05 株式会社エヌ・ティ・ティ・ドコモ 位置登録制御方法、移動通信網および通信端末

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