AU4540193A - Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo{a,d}cyclohepten-5,10-imine - Google Patents

Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo{a,d}cyclohepten-5,10-imine

Info

Publication number
AU4540193A
AU4540193A AU45401/93A AU4540193A AU4540193A AU 4540193 A AU4540193 A AU 4540193A AU 45401/93 A AU45401/93 A AU 45401/93A AU 4540193 A AU4540193 A AU 4540193A AU 4540193 A AU4540193 A AU 4540193A
Authority
AU
Australia
Prior art keywords
cyclohepten
dibenzo
aminocarbonyl
hypoxia
imine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45401/93A
Inventor
Michael A. Rogawski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
US Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, US Government filed Critical US Department of Health and Human Services
Publication of AU4540193A publication Critical patent/AU4540193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
AU45401/93A 1992-06-17 1993-06-16 Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo{a,d}cyclohepten-5,10-imine Abandoned AU4540193A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89973492A 1992-06-17 1992-06-17
US899734 1992-06-17
PCT/US1993/005845 WO1993025203A1 (en) 1992-06-17 1993-06-16 Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo[a,d]cyclohepten-5,10-imine

Publications (1)

Publication Number Publication Date
AU4540193A true AU4540193A (en) 1994-01-04

Family

ID=25411485

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45401/93A Abandoned AU4540193A (en) 1992-06-17 1993-06-16 Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo{a,d}cyclohepten-5,10-imine

Country Status (2)

Country Link
AU (1) AU4540193A (en)
WO (1) WO1993025203A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6413948B1 (en) 1996-09-27 2002-07-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of effecting a neuronal activity in an animal using naaladase inhibitors

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271623B (en) * 1994-03-21 1997-06-04 Lifegroup Spa N-ACYL DERIVATIVES OF AMINO-ALCOHOLS WITH MONOCARBOSSYL AND BICARBOSSYLIC ACIDS WITH NEUROPROTECTIVE ACTIVITY IN NEUROLOGICAL DISEASES RELATED TO EXCITOTOXICITY
WO1998041523A1 (en) * 1997-03-20 1998-09-24 Neurogen Corporation Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo(3.2.1.) octanes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8600783D0 (en) * 1986-01-14 1986-02-19 Merck Sharp & Dohme N-methyl-d-aspartate receptor antagonists
NZ221626A (en) * 1986-09-08 1989-11-28 Merck & Co Inc Dibenzo(a,d cycloheptene derivatives and pharmaceutical compositions
US5011834A (en) * 1989-04-14 1991-04-30 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon PCP receptor ligands and the use thereof
JPH07119224B2 (en) * 1989-05-09 1995-12-20 アメリカ合衆国 5-Aminocarbonyl-5H-dibenzo [a, d] cycloheptene-5,10-imine for the treatment of epilepsy and cocaine addiction

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US5985855A (en) * 1996-09-27 1999-11-16 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using NAALADase inhibitors
US6004946A (en) * 1996-09-27 1999-12-21 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6413948B1 (en) 1996-09-27 2002-07-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of effecting a neuronal activity in an animal using naaladase inhibitors

Also Published As

Publication number Publication date
WO1993025203A1 (en) 1993-12-23

Similar Documents

Publication Publication Date Title
AU1875692A (en) Exhaust treatment system and method
AU4861493A (en) Clear leave-on treatment composition and method
AU4767993A (en) Ballistic-resistant article and process for making the same
AU7935294A (en) Mechanisms for orienting and placing articles
AU3606493A (en) Dealer information and security apparatus and method
AU7080594A (en) Method and apparatus for spectrophotometric cerebral oximetry
AU4136496A (en) Method and apparatus for distributing log i/o activity
AU3208793A (en) Abrasive article and method
AU5052093A (en) Laminating method and products made thereby
AU5853394A (en) Neutron-capture therapy apparatus and method
AU4428493A (en) Aroma-imparting method and aroma-emitting textile product
AU6372696A (en) Fastener means for absorbent articles, and a method of producing absorbent articles provided with fastener means that include locking elements
AU4089493A (en) K-filter for serial high-speed rotatography, and apparatus for the rotatography
AU6001094A (en) Tnf-alpha muteins and a process for preparing them
AU7752694A (en) Method for preventing hair loss and stimulating new hair growth
AU1146788A (en) Open-ended multipack with carrying strap and method
AU2322392A (en) Method and assay system for neurotrophin activity
AU4425293A (en) Improved intumescence carriers and their use
AU583878B2 (en) Partially oriented nylon yarn and process
AU7969994A (en) Keratorefractive system and method
AU4540193A (en) Method of treating and protecting against central nervous system ischemia, hypoxia, degeneration, and trauma with a 5-aminocarbonyl-sh-dibenzo{a,d}cyclohepten-5,10-imine
AU7589294A (en) Rotary article storage and outfeed apparatus
AU2246692A (en) Fastener coating and process
AU4713193A (en) Electrodialyzer and process for desalination
AU5922094A (en) 3-quinolyl-substituted dihydropyridines, processes for theirpreparation and their use in medicaments