JP2002512190A5 - - Google Patents
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- Publication number
- JP2002512190A5 JP2002512190A5 JP2000544324A JP2000544324A JP2002512190A5 JP 2002512190 A5 JP2002512190 A5 JP 2002512190A5 JP 2000544324 A JP2000544324 A JP 2000544324A JP 2000544324 A JP2000544324 A JP 2000544324A JP 2002512190 A5 JP2002512190 A5 JP 2002512190A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- latent
- centrifuged
- supernatant
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 C**(N*=C)=C Chemical compound C**(N*=C)=C 0.000 description 4
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19818044A DE19818044A1 (de) | 1998-04-22 | 1998-04-22 | Verwendung von Vitamin-PP-Verbindungen |
| DE19818044.6 | 1998-04-22 | ||
| PCT/EP1999/002686 WO1999053920A1 (en) | 1998-04-22 | 1999-04-21 | Use of vitamin pp compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002512190A JP2002512190A (ja) | 2002-04-23 |
| JP2002512190A5 true JP2002512190A5 (enExample) | 2010-02-25 |
| JP4607319B2 JP4607319B2 (ja) | 2011-01-05 |
Family
ID=7865483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000544324A Expired - Fee Related JP4607319B2 (ja) | 1998-04-22 | 1999-04-21 | ビタミンpp化合物の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100227896A1 (enExample) |
| EP (1) | EP1079832B1 (enExample) |
| JP (1) | JP4607319B2 (enExample) |
| AT (1) | ATE311186T1 (enExample) |
| AU (1) | AU3928299A (enExample) |
| DE (2) | DE19818044A1 (enExample) |
| DK (1) | DK1079832T3 (enExample) |
| ES (1) | ES2253890T3 (enExample) |
| WO (1) | WO1999053920A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5296799A (en) * | 1998-08-03 | 2000-02-28 | N-Gene Kutato Kft. | Pharmaceutical compositions against autoimmune diseases |
| GB0104240D0 (en) * | 2001-02-21 | 2001-04-11 | Clariant Int Ltd | Copolymer composition having pigment like properties |
| EP1348434A1 (en) * | 2002-03-27 | 2003-10-01 | Fujisawa Deutschland GmbH | Use of pyridyl amides as inhibitors of angiogenesis |
| US8067457B2 (en) | 2005-11-01 | 2011-11-29 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of CCR2 |
| US8067415B2 (en) | 2005-11-01 | 2011-11-29 | Millennium Pharmaceuticals, Inc. | Compounds useful as antagonists of CCR2 |
| EP2197443A4 (en) * | 2007-09-26 | 2014-01-01 | Gemin X Pharmaceuticals Canada Inc | COMPOSITIONS AND METHOD FOR LEADING NAD + MIRRORS USING A NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE HEMMER |
| EP2213288A1 (en) * | 2009-01-30 | 2010-08-04 | Karl Welte | NAMPT and vitamin B3 for treating or preventing diseases |
| CA2768338A1 (en) | 2009-07-17 | 2011-01-20 | Topotarget A/S | Method for predicting the utility of administering nicotinic acid or a precursor or prodrug thereof to reduce the severity of side-effects of cancer treatment with nicotinamide phosphoribosyltransferase inhibitors |
| US8912184B1 (en) | 2010-03-01 | 2014-12-16 | Alzheimer's Institute Of America, Inc. | Therapeutic and diagnostic methods |
| US9889222B2 (en) | 2011-11-09 | 2018-02-13 | Kimberly-Clark Worldwide, Inc. | Aqueous medium-sensitive coating compositions for triggered release of active ingredients and visual indication for wetness |
| US8791045B2 (en) | 2011-11-09 | 2014-07-29 | Kimberly-Clark Worldwide, Inc. | Non-tacky wetness indicator composition for application on a polymeric substrate |
| US9585826B2 (en) | 2012-11-07 | 2017-03-07 | Kimberly-Clark Worldwide, Inc. | Triggerable compositions for two-stage, controlled release of active chemistry |
| HK1215579A1 (zh) | 2012-11-29 | 2016-09-02 | Karyopharm Therapeutics, Inc. | 被取代的2,3-二氫苯並呋喃基化合物和其用途 |
| US9856241B2 (en) | 2013-07-03 | 2018-01-02 | Karyopharm Therapeutics Inc. | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof |
| WO2015042414A1 (en) | 2013-09-20 | 2015-03-26 | Karyopharm Therapeutics Inc. | Multicyclic compounds and methods of using same |
| US9119780B2 (en) | 2013-10-30 | 2015-09-01 | Kimberly-Clark Worldwide, Inc. | Triggerable compositions for two-stage, controlled release of proactive chemistry |
| MX2018001979A (es) | 2015-08-18 | 2019-04-25 | Karyopharm Therapeutics Inc | (s,e) -3- (6-aminopiridin-3-il) -n- ( (5- (4- (3-fluoruro-3 metilpirrolidin-1-carbonil) fenil) -7- (4 fluorofenil) benzofuran-2-il)metil)acrilamida para el tratamiento del cancer. |
| US10858347B2 (en) | 2015-12-31 | 2020-12-08 | Karyopharm Therapeutics Inc. | Multicyclic compounds and uses thereof |
| RU2651047C1 (ru) * | 2017-05-04 | 2018-04-18 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Лекарственная композиция цитопротекторного действия и способ ее получения |
| US11584766B2 (en) | 2018-02-05 | 2023-02-21 | The Trustees Of Indiana University | Nicotinamide phosphoribosyltransferase inhibitors and methods for use of the same |
| CN115177594B (zh) * | 2022-07-04 | 2023-08-15 | 武汉大学中南医院 | 一种阿昔替尼药物制剂及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3148115A (en) * | 1958-12-08 | 1964-09-08 | Horner Frank W Ltd | Potentiation of tumor-growth inhibition from deoxypyridoxine, testosterone, or 6-mercaptopurine, by 6-aminonicotinamide |
| JPH04103538A (ja) * | 1990-08-24 | 1992-04-06 | Ajinomoto Co Inc | 制癌剤副作用抑制剤 |
| US5547927A (en) * | 1993-05-28 | 1996-08-20 | Abbott Laboratories | Enteral nutritional product for patients undergoing radiation therapy and/or chemotherapy |
| EP0771204A4 (en) * | 1994-08-12 | 1999-10-20 | Pro Neuron Inc | METHOD FOR TREATING SEPSIS OR FLAMMABLE DISEASES WITH OXYPURINE NUCLEOSIDES |
| JPH0881371A (ja) * | 1994-09-09 | 1996-03-26 | Suntory Ltd | 造血機能亢進剤 |
| AU704723B2 (en) * | 1994-12-29 | 1999-04-29 | Chugai Seiyaku Kabushiki Kaisha | Antitumor agent effect enhancer containing IL-6 antagonist |
| JP3119430B2 (ja) * | 1995-07-25 | 2000-12-18 | 大鵬薬品工業株式会社 | 水酸基ラジカル消去剤 |
| JP2860637B2 (ja) * | 1995-12-11 | 1999-02-24 | 末綱 陽子 | 新規なペプチドおよび活性化酸素阻害剤 |
| JP3836203B2 (ja) * | 1995-12-20 | 2006-10-25 | 日本臓器製薬株式会社 | 活性酸素・フリーラジカル消去剤 |
| US6451816B1 (en) * | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
| DE19624659A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalken- und Pyridylalkinsäureamide |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| DE19624668A1 (de) * | 1996-06-20 | 1998-02-19 | Klinge Co Chem Pharm Fab | Verwendung von Pyridylalkan-, Pyridylalken- bzw. Pyridylalkinsäureamiden |
| JPH1036260A (ja) * | 1996-07-18 | 1998-02-10 | Mitsui Norin Kk | 抗ガン剤の効力増強方法 |
| JPH1045594A (ja) * | 1996-07-30 | 1998-02-17 | Mitsubishi Gas Chem Co Inc | 活性酸素消去剤 |
-
1998
- 1998-04-22 DE DE19818044A patent/DE19818044A1/de not_active Ceased
-
1999
- 1999-04-21 EP EP99922119A patent/EP1079832B1/en not_active Expired - Lifetime
- 1999-04-21 DE DE69928660T patent/DE69928660T2/de not_active Expired - Lifetime
- 1999-04-21 AT AT99922119T patent/ATE311186T1/de active
- 1999-04-21 DK DK99922119T patent/DK1079832T3/da active
- 1999-04-21 JP JP2000544324A patent/JP4607319B2/ja not_active Expired - Fee Related
- 1999-04-21 WO PCT/EP1999/002686 patent/WO1999053920A1/en not_active Ceased
- 1999-04-21 ES ES99922119T patent/ES2253890T3/es not_active Expired - Lifetime
- 1999-04-21 AU AU39282/99A patent/AU3928299A/en not_active Abandoned
-
2010
- 2010-05-13 US US12/779,698 patent/US20100227896A1/en not_active Abandoned
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