JP2002509694A - 特異的かつ高感度な核酸検出方法 - Google Patents
特異的かつ高感度な核酸検出方法Info
- Publication number
- JP2002509694A JP2002509694A JP2000519104A JP2000519104A JP2002509694A JP 2002509694 A JP2002509694 A JP 2002509694A JP 2000519104 A JP2000519104 A JP 2000519104A JP 2000519104 A JP2000519104 A JP 2000519104A JP 2002509694 A JP2002509694 A JP 2002509694A
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- Prior art keywords
- nucleic acid
- sequence
- binding
- probe
- detected
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Engineering & Computer Science (AREA)
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- Biotechnology (AREA)
- Biophysics (AREA)
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- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| DE19748690A DE19748690A1 (de) | 1997-11-04 | 1997-11-04 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19814001A DE19814001A1 (de) | 1998-03-28 | 1998-03-28 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| DE19814001.0 | 1998-04-02 | ||
| DE19748690.8 | 1998-04-02 | ||
| DE19814828.3 | 1998-04-02 | ||
| DE19814828A DE19814828A1 (de) | 1998-04-02 | 1998-04-02 | Spezifisches und sensitives Nukleinsäurenachweisverfahren |
| PCT/EP1998/006952 WO1999023249A2 (de) | 1997-11-04 | 1998-11-03 | Spezifisches und empfindliches nukleinsäurenachweisverfahren |
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| JP2002509694A true JP2002509694A (ja) | 2002-04-02 |
| JP2002509694A5 JP2002509694A5 (https=) | 2006-01-05 |
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| JP2000519105A Pending JP2002505071A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519599A Pending JP2001521765A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
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| JP2000519105A Pending JP2002505071A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
| JP2000519599A Pending JP2001521765A (ja) | 1997-11-04 | 1998-11-03 | 特異的かつ高感度な核酸検出方法 |
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| US (1) | US7105318B2 (https=) |
| EP (3) | EP1029077A2 (https=) |
| JP (3) | JP2002509694A (https=) |
| AU (3) | AU741141B2 (https=) |
| CA (3) | CA2308762A1 (https=) |
| WO (3) | WO1999024606A2 (https=) |
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| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| WO1999031273A2 (en) * | 1997-12-12 | 1999-06-24 | Digene Corporation | Universal collection medium |
| US6361942B1 (en) | 1998-03-24 | 2002-03-26 | Boston Probes, Inc. | Method, kits and compositions pertaining to detection complexes |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7807802B2 (en) | 2002-11-12 | 2010-10-05 | Abbott Lab | Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae |
| EP3121286B1 (en) | 2006-12-21 | 2019-11-20 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| JP2010521156A (ja) * | 2007-03-16 | 2010-06-24 | ４５４ ライフ サイエンシーズ コーポレイション | Ｈｉｖ薬物耐性バリアントの検出のためのシステムおよび方法 |
| GB0714389D0 (en) | 2007-07-21 | 2007-09-05 | Barry Callebaut Ag | Process and product |
| JP2011518333A (ja) * | 2008-04-17 | 2011-06-23 | キアジェン ゲイサーズバーグ インコーポレイテッド | 標的核酸の存在を判別するための合成プローブを用いた組成物、方法、およびキット |
| WO2010062546A1 (en) | 2008-10-27 | 2010-06-03 | Qiagen Gaithersburg Inc. | Fast results hybrid capture assay on an automated platform |
| JP6108661B2 (ja) * | 2009-01-28 | 2017-04-05 | キアジェン ゲイサーズバーグ インコーポレイテッド | 配列特異的な大量試料調製方法およびアッセイ法 |
| EP2425019B1 (en) * | 2009-05-01 | 2014-03-19 | QIAGEN Gaithersburg, Inc. | A non-target amplification method for detection of rna splice-forms in a sample |
| EP2449132B1 (en) | 2009-07-01 | 2015-05-13 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| JP5826752B2 (ja) | 2009-09-14 | 2015-12-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法 |
| CA2787924A1 (en) | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| CA2787781A1 (en) | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Method of determining and confirming the presence of an hpv in a sample |
| JP2013528049A (ja) | 2010-05-19 | 2013-07-08 | キアゲン ガイサーズバーグ アイエヌシー． | 核酸の配列特異的な精製及び多重分析のための方法及び組成物 |
| JP6153866B2 (ja) | 2010-05-25 | 2017-06-28 | キアゲン ガイサーズバーグ アイエヌシー． | 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ |
| CN103597095B (zh) | 2011-02-24 | 2016-08-17 | 奇亚根盖瑟斯堡股份有限公司 | 用于检测hpv核酸的材料和方法 |
| JP2024097096A (ja) * | 2021-04-28 | 2024-07-18 | バイオニクス株式会社 | 光学測定装置 |
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| CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| US5200313A (en) * | 1983-08-05 | 1993-04-06 | Miles Inc. | Nucleic acid hybridization assay employing detectable anti-hybrid antibodies |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| AU606043B2 (en) * | 1985-03-28 | 1991-01-31 | F. Hoffmann-La Roche Ag | Detection of viruses by amplification and hybridization |
| ES286841Y (es) | 1985-05-20 | 1988-10-01 | Vileda Gmbh | Dispositivo de acoplamiento de un mango a un util de limpieza |
| CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
| US5639871A (en) * | 1988-09-09 | 1997-06-17 | Roche Molecular Systems, Inc. | Detection of human papillomavirus by the polymerase chain reaction |
| FI911152A7 (fi) | 1989-07-11 | 1991-03-07 | Gen Probe Inc | Nukleiinihapposekvenssin amplifikaatiomenetelmät |
| NL9000134A (nl) * | 1990-01-19 | 1991-08-16 | Stichting Res Fonds Pathologie | Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr. |
| US5453355A (en) * | 1990-01-26 | 1995-09-26 | Abbott Laboratories | Oligonucleotides and methods for the detection of Neisseria gonorrhoeae |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| SK284205B6 (sk) * | 1991-05-08 | 2004-10-05 | Chiron Corporation | Prirodzene sa nevyskytujúca nukleová kyselina, spôsob tvorby hybridizačného produktu a spôsob detekcie genotypov HCV |
| ATE161291T1 (de) | 1991-08-27 | 1998-01-15 | Hoffmann La Roche | Verfahren und reagenzien zum nachweis von hepatitis c |
| JPH05308999A (ja) * | 1992-05-08 | 1993-11-22 | Sumitomo Metal Ind Ltd | Ｂ型肝炎ウイルスｐｒｅ−Ｃ変異の判定法 |
| WO1994003635A1 (en) | 1992-08-04 | 1994-02-17 | Institute Of Molecular Biology & Biotechnology | Rapid amplification and detection of nucleic acids |
| US5605798A (en) * | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
| WO1995002690A1 (en) * | 1993-07-13 | 1995-01-26 | Abbott Laboratories | Nucleotide sequences and process for amplifying and detection of hepatitis b virus |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| AT406019B (de) * | 1995-05-08 | 2000-01-25 | Immuno Ag | Verfahren zur herstellung eines arzneimittels enthaltend ein oder mehrere plasmaderivate |
| US5882857A (en) * | 1995-06-07 | 1999-03-16 | Behringwerke Ag | Internal positive controls for nucleic acid amplification |
| EP1033411B1 (en) * | 1996-06-04 | 2006-02-22 | University of Utah Research Foundation | Fluorescent donor-acceptor pair |
| US5858671A (en) * | 1996-11-01 | 1999-01-12 | The University Of Iowa Research Foundation | Iterative and regenerative DNA sequencing method |
| US6333179B1 (en) * | 1997-06-20 | 2001-12-25 | Affymetrix, Inc. | Methods and compositions for multiplex amplification of nucleic acids |
| AU758463B2 (en) * | 1998-02-04 | 2003-03-20 | Applied Biosystems, Llc | Determination of a genotype of an amplification product at multiple allelic sites |
| US5948648A (en) * | 1998-05-29 | 1999-09-07 | Khan; Shaheer H. | Nucleotide compounds including a rigid linker |
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|---|---|
| WO1999023249A2 (de) | 1999-05-14 |
| AU2152199A (en) | 1999-05-24 |
| WO1999024606A3 (de) | 1999-07-22 |
| WO1999024606A2 (de) | 1999-05-20 |
| CA2308368C (en) | 2009-01-20 |
| EP1029083A2 (de) | 2000-08-23 |
| CA2308762A1 (en) | 1999-05-14 |
| EP1029084A2 (de) | 2000-08-23 |
| WO1999023250A3 (de) | 1999-07-22 |
| US7105318B2 (en) | 2006-09-12 |
| CA2312779A1 (en) | 1999-05-20 |
| US20030175765A1 (en) | 2003-09-18 |
| JP2002505071A (ja) | 2002-02-19 |
| AU1232099A (en) | 1999-05-24 |
| WO1999023250A2 (de) | 1999-05-14 |
| CA2308368A1 (en) | 1999-05-14 |
| WO1999023249A3 (de) | 1999-09-10 |
| AU2152099A (en) | 1999-05-31 |
| AU741141B2 (en) | 2001-11-22 |
| JP2001521765A (ja) | 2001-11-13 |
| EP1029077A2 (de) | 2000-08-23 |
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