|
US6403597B1
(en)
|
1997-10-28 |
2002-06-11 |
Vivus, Inc. |
Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
|
|
US6548490B1
(en)
|
1997-10-28 |
2003-04-15 |
Vivus, Inc. |
Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
|
|
AU7654200A
(en)
*
|
1999-09-14 |
2001-04-17 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Phthalazinone derivatives as pd3/4 inhibitors
|
|
IL148807A0
(en)
|
1999-10-25 |
2002-09-12 |
Byk Gulden Lomberg Chem Fab |
Tetrahydrothiopyran derivatives and pharmaceutical compositions containing the same
|
|
DE60036558D1
(de)
|
1999-10-25 |
2007-11-08 |
Nycomed Gmbh |
Phthalazinon-derivate als pde 4 hemmer
|
|
WO2002012266A1
(en)
|
2000-08-05 |
2002-02-14 |
Glaxo Group Limited |
17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents
|
|
GB0103630D0
(en)
|
2001-02-14 |
2001-03-28 |
Glaxo Group Ltd |
Chemical compounds
|
|
EE05386B1
(et)
*
|
2001-02-15 |
2011-02-15 |
ALTANA�Pharma�AG |
Ftalasinoon-piperidinoderivaadid,ÁnendeÁkasutamineÁjaÁravim
|
|
JP4143413B2
(ja)
|
2001-03-22 |
2008-09-03 |
グラクソ グループ リミテッド |
β２−アドレナリン受容体アゴニストとしてのホルムアニリド誘導体
|
|
NZ529221A
(en)
*
|
2001-04-25 |
2005-04-29 |
Altana Pharma Ag |
Phthalazinones with PDE-inhibiting properties for treatment of airway disorders and other inflammatory conditions
|
|
CZ20033205A3
(en)
*
|
2001-04-25 |
2004-03-17 |
Altana Pharma Ag |
Piperazino-derivatives and their use as pde4 inhibitor
|
|
PT1383786E
(pt)
|
2001-04-30 |
2008-12-30 |
Glaxo Group Ltd |
Derivados anti-inflamatórios de éster 17.beta-carbotioato de androstano com um grupo éster ciclíco na posição 17.alfa
|
|
WO2003008396A1
(en)
*
|
2001-07-16 |
2003-01-30 |
Nikken Chemicals Co., Ltd. |
Optically active oxazine derivative
|
|
US6479493B1
(en)
|
2001-08-23 |
2002-11-12 |
Cell Pathways, Inc. |
Methods for treatment of type I diabetes
|
|
US20030073711A1
(en)
*
|
2001-08-23 |
2003-04-17 |
Whitehead Clark M. |
Methods for treatment of scleroderma
|
|
ES2438985T3
(es)
|
2001-09-14 |
2014-01-21 |
Glaxo Group Limited |
Formulación de inhalación que comprende derivados de fenetanolamina para el tratamiento de enfermedades respiratorias
|
|
GB0201677D0
(en)
|
2002-01-25 |
2002-03-13 |
Glaxo Group Ltd |
Medicament dispenser
|
|
AU2003222841A1
(en)
|
2002-04-25 |
2003-11-10 |
Glaxo Group Limited |
Phenethanolamine derivatives
|
|
GB0217225D0
(en)
|
2002-07-25 |
2002-09-04 |
Glaxo Group Ltd |
Medicinal compounds
|
|
WO2004018450A1
(en)
*
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
|
WO2004018451A1
(en)
*
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Pyridazinone-derivatives as pde4 inhibitors
|
|
CA2494613C
(en)
*
|
2002-08-10 |
2011-06-28 |
Altana Pharma Ag |
Pyrrolidinedione substituted piperidine-phthalazones as pde4 inhibitors
|
|
AU2003255376A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-derivatives as pde4 inhibitors
|
|
ATE390407T1
(de)
|
2002-10-28 |
2008-04-15 |
Glaxo Group Ltd |
Phenethanolamin-derivate zur behandlung von atemwegserkrankungen
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
GB0303396D0
(en)
|
2003-02-14 |
2003-03-19 |
Glaxo Group Ltd |
Medicinal compounds
|
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0317374D0
(en)
|
2003-07-24 |
2003-08-27 |
Glaxo Group Ltd |
Medicament dispenser
|
|
GB0329182D0
(en)
|
2003-12-17 |
2004-01-21 |
Glaxo Group Ltd |
Chemical compounds
|
|
EP1716133B1
(en)
*
|
2004-02-04 |
2008-03-26 |
Nycomed GmbH |
2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
|
|
WO2005075437A1
(en)
*
|
2004-02-04 |
2005-08-18 |
Altana Pharma Ag |
Pyridazinone derivatives and their use as pde4 inhibitors
|
|
TWI341836B
(en)
|
2004-03-11 |
2011-05-11 |
Theravance Inc |
Biphenyl compounds useful as muscarinic receptor antagonists
|
|
AR049384A1
(es)
|
2004-05-24 |
2006-07-26 |
Glaxo Group Ltd |
Derivados de purina
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
GB0418045D0
(en)
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
|
US7569586B2
(en)
|
2004-08-16 |
2009-08-04 |
Theravance, Inc. |
Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
|
|
EP1841780B1
(en)
|
2005-01-10 |
2011-07-27 |
Glaxo Group Limited |
Androstane 17-alpha-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
|
|
UY29440A1
(es)
|
2005-03-25 |
2006-10-02 |
Glaxo Group Ltd |
Nuevos compuestos
|
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
|
TW200730498A
(en)
|
2005-12-20 |
2007-08-16 |
Glaxo Group Ltd |
Compounds
|
|
MX2008013411A
(es)
|
2006-04-20 |
2008-11-04 |
Glaxo Group Ltd |
Nuevos compuestos.
|
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
|
UA95644C2
(ru)
|
2006-07-25 |
2011-08-25 |
Сефалон, Инк. |
Пиридазиноновые производные, фармацевтическая композиция и способ лечения заболеваний
|
|
JPWO2008111631A1
(ja)
*
|
2007-03-14 |
2010-06-24 |
日本新薬株式会社 |
α−メチルベンジルアミン塩の製法
|
|
PE20081889A1
(es)
|
2007-03-23 |
2009-03-05 |
Smithkline Beecham Corp |
Indol carboxamidas como inhibidores de ikk2
|
|
US7943658B2
(en)
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
|
JP5791500B2
(ja)
|
2008-05-23 |
2015-10-07 |
パンミラ ファーマシューティカルズ，エルエルシー． |
５−リポキシゲナーゼ活性化タンパク質阻害剤
|
|
ES2566339T3
(es)
|
2008-06-05 |
2016-04-12 |
Glaxo Group Limited |
Derivados de 4-carboxamida indazol útiles como inhibidores de PI3-quinasas
|
|
ES2552320T3
(es)
|
2008-06-24 |
2015-11-27 |
F. Hoffmann-La Roche Ag |
Nuevas piridín-2-onas y piridazín-3-onas sustituidas
|
|
BRPI0913879A2
(pt)
|
2008-07-02 |
2019-09-24 |
Hoffmann La Roche |
fenilpirazinonas como inibidores de quinase
|
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
|
JP5656880B2
(ja)
|
2009-03-09 |
2015-01-21 |
グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ |
Ｐｉ３キナーゼの阻害剤としての４−オキサジアゾール−２−イル−インダゾール
|
|
WO2010102968A1
(en)
|
2009-03-10 |
2010-09-16 |
Glaxo Group Limited |
Indole derivatives as ikk2 inhibitors
|
|
WO2010106016A1
(en)
|
2009-03-17 |
2010-09-23 |
Glaxo Group Limited |
Pyrimidine derivatives used as itk inhibitors
|
|
EP2408917A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF BTB AND CNC HOMOLOGY 1, BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR 1 (BACH 1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) SEQUENCE LISTING
|
|
EP2408458A1
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
WO2010107952A2
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
EP2408915A2
(en)
|
2009-03-19 |
2012-01-25 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
JP2012521760A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸（ｓｉＮＡ）を用いたアポトーシスシグナル調節キナーゼ１（ＡＳＫ１）遺伝子発現のＲＮＡ干渉媒介性阻害
|
|
JP2012521764A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸（ｓｉＮＡ）を用いた胸腺間質性リンパ球新生因子（ＴＳＬＰ）遺伝子発現のＲＮＡ干渉媒介性阻害
|
|
US20120004281A1
(en)
|
2009-03-27 |
2012-01-05 |
Merck Sharp & Dohme Corp |
RNA Interference Mediated Inhibition of the Nerve Growth Factor Beta Chain (NGFB) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
WO2010111471A2
(en)
|
2009-03-27 |
2010-09-30 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
AU2010229847A1
(en)
|
2009-03-27 |
2011-10-13 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of the intercellular adhesion molecule 1 (ICAM-1)gene expression using short interfering nucleic acid (siNA)
|
|
WO2010122088A1
(en)
|
2009-04-24 |
2010-10-28 |
Glaxo Group Limited |
Pyrazole and triazole carboxamides as crac channel inhibitors
|
|
UY32571A
(es)
|
2009-04-24 |
2010-11-30 |
Glaxo Group Ltd |
Compuestos derivados de pirazol amida
|
|
WO2010125082A1
(en)
|
2009-04-30 |
2010-11-04 |
Glaxo Group Limited |
Oxazole substituted indazoles as pi3-kinase inhibitors
|
|
DK2453894T3
(en)
|
2009-07-15 |
2016-01-25 |
Theravance Biopharma R&D Ip Llc |
Crystalline free base of a biphenyl compound
|
|
US20120245171A1
(en)
|
2009-12-03 |
2012-09-27 |
Glaxo Group Limited |
Benzpyrazole derivatives as inhibitors of pi3 kinases
|
|
EP2507231A1
(en)
|
2009-12-03 |
2012-10-10 |
Glaxo Group Limited |
Indazole derivatives as pi 3 - kinase inhibitors
|
|
EP2507226A1
(en)
|
2009-12-03 |
2012-10-10 |
Glaxo Group Limited |
Novel compounds
|
|
EP2512438B1
(en)
|
2009-12-16 |
2017-01-25 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
|
RS54286B1
(sr)
|
2010-09-08 |
2016-02-29 |
Glaxosmithkline Intellectual Property Development Limited |
Polimorfi i soli n-[5-[4-(5-{[(2r,6s)-2,6-dimetil-4-morfolinil]metil}-1,3-oksazol-2-il)-1h-indazol-6-il]-2(metiloksi)-3-piridinil]-metansulfonamida
|
|
US9326987B2
(en)
|
2010-09-08 |
2016-05-03 |
Glaxo Group Limited |
Indazole derivatives for use in the treatment of influenza virus infection
|
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
|
US9149462B2
(en)
|
2010-10-21 |
2015-10-06 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, inflammatory and immune disorders
|
|
ES2532213T3
(es)
|
2010-10-21 |
2015-03-25 |
Glaxo Group Limited |
Compuestos de pirazol que actúan contra afecciones alérgicas, inmunitarias e inflamatorias
|
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
|
US20140005188A1
(en)
|
2011-03-11 |
2014-01-02 |
Glaxo Group Limited |
Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
|
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
|
AU2012269133A1
(en)
*
|
2011-06-17 |
2014-01-30 |
Takeda Gmbh |
Novel phthalazinone-pyrrolopyrimidinecarboxamide derivatives
|
|
WO2013106547A1
(en)
|
2012-01-10 |
2013-07-18 |
President And Fellows Of Harvard College |
Beta-cell replication promoting compounds and methods of their use
|
|
MX365950B
(es)
|
2013-03-13 |
2019-06-19 |
Flatley Discovery Lab Llc |
Compuestos de piridazinona y metodos para el tratamiento de la fibrosis quistica.
|
|
WO2014159776A1
(en)
*
|
2013-03-14 |
2014-10-02 |
Cephalon, Inc. |
Solid state forms of 6-[4-[3-(r)-2-methylpyrrolidine-1-yl)-propoxy]phenyl]2h-pyridazine-3-one hydrochloride
|
|
KR20160062178A
(ko)
|
2013-10-17 |
2016-06-01 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
호흡기 질병의 치료를 위한 ｐｉ３ｋ 억제제
|
|
JP2016537327A
(ja)
|
2013-10-17 |
2016-12-01 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ |
呼吸器疾患の治療のためのｐｉ３ｋ阻害剤
|
|
US20170100385A1
(en)
|
2014-05-12 |
2017-04-13 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Pharmaceutical compositions comprising danirixin for treating infectious diseases
|
|
JP6506836B2
(ja)
|
2014-08-14 |
2019-04-24 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｂ型肝炎ウイルス感染症の処置および予防のための新規ピリダゾンおよびトリアジノン
|
|
CN104478809B
(zh)
*
|
2014-11-14 |
2016-08-17 |
成都新恒创药业有限公司 |
一种左西孟旦杂质及其制备和检测方法
|
|
GB201602527D0
(en)
|
2016-02-12 |
2016-03-30 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
WO2018029126A1
(en)
|
2016-08-08 |
2018-02-15 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
|
WO2018094392A1
(en)
|
2016-11-21 |
2018-05-24 |
Lupin Inc. |
Medicament dispenser
|
|
GB201706102D0
(en)
|
2017-04-18 |
2017-05-31 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
GB201712081D0
(en)
|
2017-07-27 |
2017-09-13 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
US20210085897A1
(en)
|
2018-04-06 |
2021-03-25 |
Lupin Inc. |
Medicament dispenser
|
|
WO2020058823A1
(en)
|
2018-09-17 |
2020-03-26 |
Lupin, Inc. |
Dose indicator assembly for a medicament dispenser
|
|
CN115916305B
(zh)
|
2020-03-25 |
2025-03-21 |
陆品公司 |
多载体药物分配器
|
|
CN116210004A
(zh)
|
2020-07-23 |
2023-06-02 |
鲁平股份有限公司 |
用于药剂分配器的剂量计数器组件
|