JP2003502367A5 - - Google Patents

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Publication number
JP2003502367A5
JP2003502367A5 JP2001504372A JP2001504372A JP2003502367A5 JP 2003502367 A5 JP2003502367 A5 JP 2003502367A5 JP 2001504372 A JP2001504372 A JP 2001504372A JP 2001504372 A JP2001504372 A JP 2001504372A JP 2003502367 A5 JP2003502367 A5 JP 2003502367A5
Authority
JP
Japan
Prior art keywords
group
compound
formula
aryl
dichlorobenzyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001504372A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003502367A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/017244 external-priority patent/WO2000078309A1/en
Publication of JP2003502367A publication Critical patent/JP2003502367A/ja
Publication of JP2003502367A5 publication Critical patent/JP2003502367A5/ja
Pending legal-status Critical Current

Links

JP2001504372A 1999-06-23 2000-06-22 インドール化合物 Pending JP2003502367A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14055899P 1999-06-23 1999-06-23
US60/140,558 1999-06-23
PCT/US2000/017244 WO2000078309A1 (en) 1999-06-23 2000-06-22 Indole compounds

Publications (2)

Publication Number Publication Date
JP2003502367A JP2003502367A (ja) 2003-01-21
JP2003502367A5 true JP2003502367A5 (https=) 2007-08-23

Family

ID=22491792

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001504372A Pending JP2003502367A (ja) 1999-06-23 2000-06-22 インドール化合物

Country Status (7)

Country Link
US (1) US6469046B1 (https=)
EP (1) EP1187607A4 (https=)
JP (1) JP2003502367A (https=)
AU (1) AU5633300A (https=)
CO (1) CO5180605A1 (https=)
HK (1) HK1044481A1 (https=)
WO (1) WO2000078309A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
CO5370679A1 (es) 1999-06-01 2004-02-27 Smithkline Beecham Corp Inhibidores fab 1
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
HU230030B1 (hu) 1999-10-08 2015-05-28 Debiopharm International Sa Fab I inhibitorok
EP1560584B1 (en) * 2001-04-06 2009-01-14 Affinium Pharmaceuticals, Inc. Fab i inhibitors
EP1575951B1 (en) * 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
DK1828167T3 (da) * 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
KR20080075027A (ko) * 2005-12-05 2008-08-13 아피늄 파마슈티컬스, 인크. Fabi 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
KR20080114711A (ko) * 2006-03-02 2008-12-31 아스텔라스세이야쿠 가부시키가이샤 17β HSD 타입 5 저해제
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ, インク. Fabiインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
WO2012064642A1 (en) * 2010-11-08 2012-05-18 Glaxosmithkline Llc Fatty acid synthase inhibitors
AU2013279021C1 (en) 2012-06-19 2017-03-16 Debiopharm International Sa Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
ES2753386T3 (es) 2013-03-13 2020-04-08 Forma Therapeutics Inc Derivados de 2-hidroxi-1-{4-[(4-fenil)fenil]carbonil}piperazin-1-il}etano-1-ona y compuestos relacionados como inhibidores de sintasa de ácido graso (FASN) para el tratamiento del cáncer
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
WO2019199979A1 (en) * 2018-04-10 2019-10-17 The General Hospital Corporation Antibacterial compounds
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
US10793554B2 (en) 2018-10-29 2020-10-06 Forma Therapeutics, Inc. Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone
TN2021000159A1 (en) 2019-02-14 2023-04-04 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
SG11202113174SA (en) 2019-06-14 2021-12-30 Debiopharm Int Sa Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482960A (en) 1994-11-14 1996-01-09 Warner-Lambert Company Nonpeptide endothelin antagonists

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