JP2002502882A - インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン - Google Patents
インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチンInfo
- Publication number
- JP2002502882A JP2002502882A JP2000531187A JP2000531187A JP2002502882A JP 2002502882 A JP2002502882 A JP 2002502882A JP 2000531187 A JP2000531187 A JP 2000531187A JP 2000531187 A JP2000531187 A JP 2000531187A JP 2002502882 A JP2002502882 A JP 2002502882A
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- suspension
- interleukin
- vaccine
- carrier molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7452898P | 1998-02-12 | 1998-02-12 | |
| US60/074,528 | 1998-02-12 | ||
| PCT/US1999/002847 WO1999040936A2 (en) | 1998-02-12 | 1999-02-10 | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009193167A Division JP2010006827A (ja) | 1998-02-12 | 2009-08-24 | インターロイキン−12とともに処方された髄膜炎菌のワクチン |
| JP2010144063A Division JP2010265279A (ja) | 1998-02-12 | 2010-06-24 | インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002502882A true JP2002502882A (ja) | 2002-01-29 |
| JP2002502882A5 JP2002502882A5 (enExample) | 2006-03-02 |
Family
ID=22120049
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000531187A Pending JP2002502882A (ja) | 1998-02-12 | 1999-02-10 | インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン |
| JP2009193167A Pending JP2010006827A (ja) | 1998-02-12 | 2009-08-24 | インターロイキン−12とともに処方された髄膜炎菌のワクチン |
| JP2010144063A Pending JP2010265279A (ja) | 1998-02-12 | 2010-06-24 | インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009193167A Pending JP2010006827A (ja) | 1998-02-12 | 2009-08-24 | インターロイキン−12とともに処方された髄膜炎菌のワクチン |
| JP2010144063A Pending JP2010265279A (ja) | 1998-02-12 | 2010-06-24 | インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1053015A2 (enExample) |
| JP (3) | JP2002502882A (enExample) |
| KR (1) | KR100585408B1 (enExample) |
| CN (1) | CN1200730C (enExample) |
| AU (1) | AU759391B2 (enExample) |
| BR (1) | BR9907884A (enExample) |
| CA (1) | CA2320223A1 (enExample) |
| IL (2) | IL137809A0 (enExample) |
| WO (1) | WO1999040936A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010265279A (ja) * | 1998-02-12 | 2010-11-25 | Wyeth Holdings Corp | インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6908757B1 (en) | 1998-03-26 | 2005-06-21 | The Procter & Gamble Company | Serine protease variants having amino acid deletions and substitutions |
| CN1373802A (zh) | 1999-07-22 | 2002-10-09 | 宝洁公司 | 在特定表位区域具有氨基酸缺失和取代的枯草杆菌蛋白酶变体 |
| EP1196548A2 (en) | 1999-07-22 | 2002-04-17 | The Procter & Gamble Company | Protease conjugates having sterically protected clip sites |
| US6946128B1 (en) | 1999-07-22 | 2005-09-20 | The Procter & Gamble Company | Protease conjugates having sterically protected epitope regions |
| EP1210415A2 (en) | 1999-07-22 | 2002-06-05 | The Procter & Gamble Company | Subtilisin protease variants having amino acid substitutions in defined epitope regions |
| MXPA05003863A (es) | 2002-10-11 | 2005-09-08 | Chiron Srl | Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos. |
| JP4827726B2 (ja) | 2003-01-30 | 2011-11-30 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 複数の髄膜炎菌血清群に対する注射可能ワクチン |
| ES2397923T3 (es) | 2003-10-02 | 2013-03-12 | Novartis Ag | Vacunas líquidas para múltiples serogrupos meningocócicos |
| GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
| GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| NZ550533A (en) | 2004-04-30 | 2010-02-26 | Novartis Vaccines & Diagnostic | Meningococcal conjugate vaccination comprising N. meningitidis and diphtheria toxin |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| EP2298795A1 (en) | 2005-02-18 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
| NZ561042A (en) | 2005-02-18 | 2011-03-31 | Novartis Vaccines & Diagnostic | Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli - SEQ ID: 7052 |
| EP2425856A1 (en) * | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7955605B2 (en) * | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US20090074712A1 (en) * | 2005-05-19 | 2009-03-19 | Compton | Methods for Treatment and Prevention of Infection |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| JP2010500399A (ja) | 2006-08-16 | 2010-01-07 | ノバルティス アーゲー | 尿路病原性大腸菌由来の免疫原 |
| GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
| NZ587382A (en) | 2008-02-21 | 2012-01-12 | Novartis Ag | Meningococcal fhbp polypeptides |
| AU2010220103A1 (en) | 2009-03-06 | 2011-09-22 | Novartis Ag | Chlamydia antigens |
| NZ612315A (en) | 2009-04-14 | 2014-10-31 | Novartis Ag | Compositions for immunising against staphylococcus aureus |
| MX2012000395A (es) | 2009-07-07 | 2012-02-28 | Novartis Ag | Inmunogenos conservados de escherichia coli. |
| US8871214B2 (en) | 2009-07-16 | 2014-10-28 | Novartis Ag | Detoxified Escherichia coli immunogens |
| EP3017828A1 (en) | 2009-08-27 | 2016-05-11 | GlaxoSmithKline Biologicals SA | Hybrid polypeptides including meningococcal fhbp sequences |
| EP2475385A1 (en) | 2009-09-10 | 2012-07-18 | Novartis AG | Combination vaccines against respiratory tract diseases |
| GB0917002D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Improved shigella blebs |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
| CA2776004A1 (en) | 2009-09-30 | 2011-04-07 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
| MX373250B (es) | 2009-09-30 | 2020-05-04 | Glaxosmithkline Biologicals S A Star | Conjugación de polisacáridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus. |
| GB0918392D0 (en) | 2009-10-20 | 2009-12-02 | Novartis Ag | Diagnostic and therapeutic methods |
| WO2011051893A1 (en) | 2009-10-27 | 2011-05-05 | Novartis Ag | Modified meningococcal fhbp polypeptides |
| GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
| US9173954B2 (en) | 2009-12-30 | 2015-11-03 | Glaxosmithkline Biologicals Sa | Polysaccharide immunogens conjugated to E. coli carrier proteins |
| GB201003333D0 (en) | 2010-02-26 | 2010-04-14 | Novartis Ag | Immunogenic proteins and compositions |
| GB201005625D0 (en) | 2010-04-01 | 2010-05-19 | Novartis Ag | Immunogenic proteins and compositions |
| WO2011127316A1 (en) | 2010-04-07 | 2011-10-13 | Novartis Ag | Method for generating a parvovirus b19 virus-like particle |
| GB201009861D0 (en) | 2010-06-11 | 2010-07-21 | Novartis Ag | OMV vaccines |
| EP2591097A1 (en) | 2010-07-06 | 2013-05-15 | Novartis AG | Norovirus derived immunogenic compositions and methods |
| GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
| GB201017519D0 (en) | 2010-10-15 | 2010-12-01 | Novartis Vaccines Inst For Global Health S R L | Vaccines |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| WO2012085668A2 (en) | 2010-12-24 | 2012-06-28 | Novartis Ag | Compounds |
| WO2013016460A1 (en) | 2011-07-25 | 2013-01-31 | Novartis Ag | Compositions and methods for assessing functional immunogenicity of parvovirus vaccines |
| GB201114923D0 (en) | 2011-08-30 | 2011-10-12 | Novartis Ag | Immunogenic proteins and compositions |
| US9358284B2 (en) | 2011-09-14 | 2016-06-07 | Glaxosmithkline Biologicals Sa | Methods for making saccharide-protein glycoconjugates |
| US9511130B2 (en) | 2011-09-14 | 2016-12-06 | Glaxosmithkline Biologicals Sa | Escherichia coli vaccine combination |
| CN103974718A (zh) | 2011-12-08 | 2014-08-06 | 诺华股份有限公司 | 基于艰难梭菌毒素的疫苗 |
| WO2013108272A2 (en) | 2012-01-20 | 2013-07-25 | International Centre For Genetic Engineering And Biotechnology | Blood stage malaria vaccine |
| EP2817320A1 (en) | 2012-02-24 | 2014-12-31 | Novartis AG | Pilus proteins and compositions |
| MX374919B (es) | 2012-04-26 | 2025-03-06 | Glaxosmithkline Biologicals S A Star | ANTÍGENOS Y COMBINACIONES DE ANTÍGENOS PARA USARSE PARA ELEVAR LA RESPUESTA INMUNE CONTRA Haemophilus influenzae. |
| US10279026B2 (en) | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
| MX2014014067A (es) | 2012-05-22 | 2015-02-04 | Novartis Ag | Conjugado de serogrupo x de meningococo. |
| CA2882382A1 (en) | 2012-09-18 | 2014-03-27 | Novartis Ag | Outer membrane vesicles |
| BR112015007126A2 (pt) | 2012-10-02 | 2017-08-08 | Glaxosmithkline Biologicals Sa | composição, método para induzir uma resposta imune, e, uso de uma composição |
| EP3482770B1 (en) | 2012-10-03 | 2020-11-25 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
| SG10201706671WA (en) | 2012-11-30 | 2017-09-28 | Glaxosmithkline Biologicals Sa | Pseudomonas antigens and antigen combinations |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| CN114544913B (zh) * | 2022-02-23 | 2024-04-09 | 沈阳建筑大学 | 一种土壤调查加密采样布点优化方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| CA2059693C (en) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
| US5571515A (en) * | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
| DE69529219T2 (de) * | 1994-07-01 | 2003-11-06 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Helicobacter proteine und impstoffe |
| EP0784486B1 (en) * | 1994-10-05 | 2006-04-05 | Vanderbilt University | Interleukin-12 as an adjuvant for paramyxoviridae vaccines |
| GB9422990D0 (en) * | 1994-11-15 | 1995-01-04 | Cortecs Ltd | Immunogenic compositions |
| US5866134A (en) * | 1995-03-24 | 1999-02-02 | Schering Corporation | Method for enhancing the antibody response to specific antigens with Interleukin-10 |
| AU5507098A (en) * | 1995-12-19 | 1998-03-19 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Enhancement of dna immunization through the use of cytokines |
| WO1997045139A2 (en) * | 1996-05-31 | 1997-12-04 | Genetics Institute, Inc. | Il-12 as an adjuvant for bordetella pertussis vaccines |
| US6438586B1 (en) * | 1996-09-30 | 2002-08-20 | Emc Corporation | File transfer utility which employs an intermediate data storage system |
| AU759391B2 (en) * | 1998-02-12 | 2003-04-10 | Wyeth Holdings Corporation | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
| US6303114B1 (en) * | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
-
1999
- 1999-02-10 AU AU25965/99A patent/AU759391B2/en not_active Ceased
- 1999-02-10 IL IL13780999A patent/IL137809A0/xx active IP Right Grant
- 1999-02-10 BR BR9907884-8A patent/BR9907884A/pt not_active IP Right Cessation
- 1999-02-10 WO PCT/US1999/002847 patent/WO1999040936A2/en not_active Ceased
- 1999-02-10 JP JP2000531187A patent/JP2002502882A/ja active Pending
- 1999-02-10 KR KR1020007008806A patent/KR100585408B1/ko not_active Expired - Fee Related
- 1999-02-10 CN CNB998038792A patent/CN1200730C/zh not_active Expired - Fee Related
- 1999-02-10 EP EP99905924A patent/EP1053015A2/en not_active Withdrawn
- 1999-02-10 CA CA002320223A patent/CA2320223A1/en not_active Abandoned
-
2000
- 2000-08-10 IL IL137809A patent/IL137809A/en not_active IP Right Cessation
-
2009
- 2009-08-24 JP JP2009193167A patent/JP2010006827A/ja active Pending
-
2010
- 2010-06-24 JP JP2010144063A patent/JP2010265279A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010265279A (ja) * | 1998-02-12 | 2010-11-25 | Wyeth Holdings Corp | インターロイキン−12とともに処方された肺炎球菌および髄膜炎菌のワクチン |
Also Published As
| Publication number | Publication date |
|---|---|
| IL137809A0 (en) | 2001-10-31 |
| CN1292706A (zh) | 2001-04-25 |
| KR100585408B1 (ko) | 2006-06-01 |
| AU2596599A (en) | 1999-08-30 |
| BR9907884A (pt) | 2000-10-24 |
| EP1053015A2 (en) | 2000-11-22 |
| CA2320223A1 (en) | 1999-08-19 |
| WO1999040936A2 (en) | 1999-08-19 |
| CN1200730C (zh) | 2005-05-11 |
| JP2010265279A (ja) | 2010-11-25 |
| IL137809A (en) | 2007-12-03 |
| JP2010006827A (ja) | 2010-01-14 |
| KR20010040898A (ko) | 2001-05-15 |
| WO1999040936A3 (en) | 1999-10-28 |
| AU759391B2 (en) | 2003-04-10 |
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