DE69529219T2 - Helicobacter proteine und impstoffe - Google Patents
Helicobacter proteine und impstoffeInfo
- Publication number
- DE69529219T2 DE69529219T2 DE69529219T DE69529219T DE69529219T2 DE 69529219 T2 DE69529219 T2 DE 69529219T2 DE 69529219 T DE69529219 T DE 69529219T DE 69529219 T DE69529219 T DE 69529219T DE 69529219 T2 DE69529219 T2 DE 69529219T2
- Authority
- DE
- Germany
- Prior art keywords
- helicobacter
- proteins
- vaccines
- kda
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 4
- 241000589989 Helicobacter Species 0.000 title abstract 3
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- 102000013462 Interleukin-12 Human genes 0.000 abstract 1
- 108010065805 Interleukin-12 Proteins 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 229940117681 interleukin-12 Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/121—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Helicobacter (Campylobacter) (G)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56922—Campylobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/205—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Campylobacter (G)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IE940538A IE940538A1 (en) | 1994-07-01 | 1994-07-01 | Vaccine |
IE950249 | 1995-04-06 | ||
PCT/IE1995/000036 WO1996001272A1 (en) | 1994-07-01 | 1995-07-03 | Helicobacter proteins and vaccines |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69529219D1 DE69529219D1 (en) | 2003-01-30 |
DE69529219T2 true DE69529219T2 (de) | 2003-11-06 |
Family
ID=26319740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69529219T Expired - Lifetime DE69529219T2 (de) | 1994-07-01 | 1995-07-03 | Helicobacter proteine und impstoffe |
Country Status (9)
Country | Link |
---|---|
US (2) | US20010010821A1 (de) |
EP (2) | EP0769018B1 (de) |
JP (3) | JPH10502366A (de) |
AT (1) | ATE229978T1 (de) |
AU (2) | AU696941B2 (de) |
CA (2) | CA2194236C (de) |
DE (1) | DE69529219T2 (de) |
GB (2) | GB2303855B (de) |
WO (2) | WO1996001273A1 (de) |
Families Citing this family (45)
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JP4368944B2 (ja) * | 1995-04-21 | 2009-11-18 | シーエスエル、リミテッド | 防御用ヘリコバクター抗原 |
AU6371396A (en) * | 1995-07-05 | 1997-02-05 | Randall Alexander Allardyce | Helicobacter antigens |
ES2283012T3 (es) * | 1996-01-04 | 2007-10-16 | Novartis Vaccines And Diagnostics, Inc. | Bacterioferritina de helicobacter pylori. |
ATE325621T1 (de) | 1996-05-31 | 2006-06-15 | Nat Univ Ireland Maynooth | Il-12 als adjuvanz für bordetella pertussis impfstoffe |
EP0811845B1 (de) * | 1996-06-07 | 2003-09-03 | Oxoid Limited | Vorrichtung und Testsatz zum Test von Serum und dergleichen |
DE69724515T2 (de) * | 1996-06-07 | 2004-04-01 | Oxoid Ltd., Basingstoke | Vorrichtung und Testsatz zum Test von Serum und dergleichen |
IT1289578B1 (it) * | 1996-12-06 | 1998-10-15 | Sanitaria Scaligera Spa | Immunopurificazione di un antigene dall'apparente peso molecolare di 16 +- 2 kda dell' helicobacter pylori e metodi per la sua |
AU5871598A (en) * | 1997-01-24 | 1998-08-18 | Cortecs (Uk) Limited | (h. pylori) antigens |
US6599509B2 (en) | 1997-09-02 | 2003-07-29 | Massachusetts Institute Of Technology | Compositions and methods comprising helicobacter antigens for treatment and prevention of inflammatory bowel disease |
WO1999040936A2 (en) * | 1998-02-12 | 1999-08-19 | American Cyanamid Company | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
GB9807721D0 (en) * | 1998-04-08 | 1998-06-10 | Chiron Spa | Antigen |
WO1999057278A2 (en) | 1998-04-30 | 1999-11-11 | Chiron S.P.A. | IMMUNIZATION AGAINST AND TREATMENT FOR INFECTION BY $i(H.PYLORI) |
ATE345354T1 (de) * | 2000-04-27 | 2006-12-15 | Max Planck Gesellschaft | Methode zur identifizierung von helicobacter antigenen |
US20020107368A1 (en) * | 2000-12-07 | 2002-08-08 | Jing-Hui Tian | Helicobacter proteins, gene sequences and uses thereof |
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GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
US20070059329A1 (en) | 2002-11-15 | 2007-03-15 | Nathalie Norais | Unexpected surface proteins in meningococcus |
GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
EP1654283B1 (de) | 2003-08-13 | 2011-07-13 | Novartis Vaccines and Diagnostics, Inc. | Verbessertes verfahren zur reinigung von tfpi und tfpi-analogen |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
WO2010032138A2 (en) | 2008-09-18 | 2010-03-25 | Novartis Ag | Vaccine adjuvant combinations |
BR112012002230A2 (pt) * | 2009-07-31 | 2020-08-18 | National Research Council Canada | epítopo do núcleo externo do lipopolissacarídeo do h. pylori. |
CN102740882A (zh) | 2009-08-27 | 2012-10-17 | 诺华有限公司 | 含有铝、寡核苷酸和聚阳离子的佐剂 |
ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
ES2458355T3 (es) | 2010-09-01 | 2014-05-05 | Novartis Ag | Adsorción de inmunopotenciadores sobre sales metálicas insolubles |
ES2630029T3 (es) | 2010-12-14 | 2017-08-17 | Glaxosmithkline Biologicals Sa | Análisis de citometría de flujo de materiales adsorbidos en sales metálicas |
RU2013144207A (ru) | 2011-03-02 | 2015-04-10 | Новартис Аг | Комбинированные вакцины с пониженными дозами антигена и/или адъюванта |
RU2014140336A (ru) | 2012-03-07 | 2016-04-27 | Новартис Аг | Иммунологически полезные соли аргинина |
EP2822586A1 (de) | 2012-03-07 | 2015-01-14 | Novartis AG | Adjuvierte formulierungen von streptococcus pneumoniae-antigenen |
CA2866406A1 (en) | 2012-03-08 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of booster vaccines |
WO2014006620A1 (en) | 2012-07-05 | 2014-01-09 | P.C.O.A. Devices Ltd. | Medication dispenser |
NO2879974T3 (de) | 2012-07-30 | 2018-01-20 | ||
USD776435S1 (en) | 2013-12-19 | 2017-01-17 | Colgate-Palmolive Company | Head portion of a toothbrush |
USD766581S1 (en) | 2013-12-19 | 2016-09-20 | Colgate-Palmolive Company | Electric toothbrush handle |
USD769626S1 (en) | 2013-12-19 | 2016-10-25 | Colgate-Palmolive Company | Refill head for electric toothbrush |
IL233295B (en) | 2014-06-22 | 2019-11-28 | Ilan Paz | A control pill dispensing system |
IL238387B (en) | 2015-04-20 | 2019-01-31 | Paz Ilan | Drug dispenser release mechanism |
AU2016337639B2 (en) | 2015-10-15 | 2021-07-01 | DosentRX Ltd | Image recognition-based dosage form dispensers |
WO2017077529A1 (en) | 2015-11-02 | 2017-05-11 | P.C.O.A. | Lockable advanceable oral dosage form dispenser containers |
USD790860S1 (en) | 2015-11-25 | 2017-07-04 | Colgate-Palmolive Company | Electric toothbrush brush head |
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GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
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AU5810201A (en) * | 2000-05-10 | 2001-11-20 | Aventis Pasteur | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
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-
1995
- 1995-07-03 GB GB9626484A patent/GB2303855B/en not_active Expired - Fee Related
- 1995-07-03 EP EP95922708A patent/EP0769018B1/de not_active Expired - Lifetime
- 1995-07-03 EP EP95922709A patent/EP0769019A1/de not_active Withdrawn
- 1995-07-03 GB GB9626483A patent/GB2303854B/en not_active Expired - Fee Related
- 1995-07-03 AU AU27514/95A patent/AU696941B2/en not_active Withdrawn - After Issue
- 1995-07-03 CA CA002194236A patent/CA2194236C/en not_active Expired - Fee Related
- 1995-07-03 CA CA002194237A patent/CA2194237A1/en not_active Abandoned
- 1995-07-03 WO PCT/IE1995/000037 patent/WO1996001273A1/en not_active Application Discontinuation
- 1995-07-03 AU AU27513/95A patent/AU695769B2/en not_active Ceased
- 1995-07-03 JP JP8503771A patent/JPH10502366A/ja active Pending
- 1995-07-03 DE DE69529219T patent/DE69529219T2/de not_active Expired - Lifetime
- 1995-07-03 JP JP8503770A patent/JPH10502365A/ja not_active Ceased
- 1995-07-03 WO PCT/IE1995/000036 patent/WO1996001272A1/en active IP Right Grant
- 1995-07-03 AT AT95922708T patent/ATE229978T1/de active
-
1996
- 1996-12-31 US US08/775,765 patent/US20010010821A1/en not_active Abandoned
-
2006
- 2006-06-13 JP JP2006190939A patent/JP2006348036A/ja active Pending
- 2006-09-08 US US11/518,467 patent/US20070104731A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1996001272A1 (en) | 1996-01-18 |
JPH10502366A (ja) | 1998-03-03 |
EP0769018A1 (de) | 1997-04-23 |
EP0769018B1 (de) | 2002-12-18 |
GB2303855B (en) | 1998-10-28 |
AU696941B2 (en) | 1998-09-24 |
CA2194236A1 (en) | 1996-01-18 |
GB2303855A (en) | 1997-03-05 |
JPH10502365A (ja) | 1998-03-03 |
AU2751395A (en) | 1996-01-25 |
GB2303854A (en) | 1997-03-05 |
US20070104731A1 (en) | 2007-05-10 |
GB9626484D0 (en) | 1997-02-05 |
DE69529219D1 (en) | 2003-01-30 |
GB9626483D0 (en) | 1997-02-05 |
US20010010821A1 (en) | 2001-08-02 |
CA2194237A1 (en) | 1996-01-18 |
WO1996001273A1 (en) | 1996-01-18 |
AU2751495A (en) | 1996-01-25 |
GB2303854B (en) | 1998-10-21 |
EP0769019A1 (de) | 1997-04-23 |
CA2194236C (en) | 2009-02-24 |
ATE229978T1 (de) | 2003-01-15 |
JP2006348036A (ja) | 2006-12-28 |
AU695769B2 (en) | 1998-08-20 |
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Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US |
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Owner name: THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLE, IE |