JP2001526269A5 - - Google Patents

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Publication number
JP2001526269A5
JP2001526269A5 JP2000525392A JP2000525392A JP2001526269A5 JP 2001526269 A5 JP2001526269 A5 JP 2001526269A5 JP 2000525392 A JP2000525392 A JP 2000525392A JP 2000525392 A JP2000525392 A JP 2000525392A JP 2001526269 A5 JP2001526269 A5 JP 2001526269A5
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JP
Japan
Prior art keywords
substituted
group
alkyl
twenty
perhalo substitution
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JP2000525392A
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English (en)
Japanese (ja)
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JP4395823B2 (ja
JP2001526269A (ja
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Priority claimed from PCT/US1998/026082 external-priority patent/WO1999032455A1/en
Publication of JP2001526269A publication Critical patent/JP2001526269A/ja
Publication of JP2001526269A5 publication Critical patent/JP2001526269A5/ja
Application granted granted Critical
Publication of JP4395823B2 publication Critical patent/JP4395823B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000525392A 1997-12-22 1998-12-22 アリール及びヘテロアリール置換複素環式尿素を用いたｒａｆキナーゼの阻害 Expired - Fee Related JP4395823B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99618197A 1997-12-22 1997-12-22
US08/996,181 1997-12-22
PCT/US1998/026082 WO1999032455A1 (en) 1997-12-22 1998-12-22 Inhibition of raf kinase using aryl and heteroaryl substituted heterocyclic ureas

Publications (3)

Publication Number Publication Date
JP2001526269A JP2001526269A (ja) 2001-12-18
JP2001526269A5 true JP2001526269A5 (tr) 2006-01-05
JP4395823B2 JP4395823B2 (ja) 2010-01-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000525392A Expired - Fee Related JP4395823B2 (ja) 1997-12-22 1998-12-22 アリール及びヘテロアリール置換複素環式尿素を用いたｒａｆキナーゼの阻害

Country Status (29)

Country Link
EP (1) EP1056725B1 (tr)
JP (1) JP4395823B2 (tr)
KR (1) KR100622138B1 (tr)
CN (1) CN1117081C (tr)
AT (1) ATE328873T1 (tr)
AU (1) AU765412B2 (tr)
BG (1) BG65207B1 (tr)
BR (1) BR9814361A (tr)
CA (1) CA2315713C (tr)
CU (1) CU23127A3 (tr)
CY (1) CY1105395T1 (tr)
CZ (1) CZ299836B6 (tr)
DE (2) DE1056725T1 (tr)
DK (1) DK1056725T3 (tr)
ES (1) ES2155045T3 (tr)
GR (1) GR20010300010T1 (tr)
HK (1) HK1029989A1 (tr)
HU (1) HUP0004426A3 (tr)
ID (1) ID26328A (tr)
IL (2) IL136773A0 (tr)
NO (1) NO319209B1 (tr)
NZ (1) NZ505845A (tr)
PL (1) PL341356A1 (tr)
PT (1) PT1056725E (tr)
RU (1) RU2265597C2 (tr)
SK (1) SK285371B6 (tr)
TR (3) TR200100918T2 (tr)
UA (1) UA67763C2 (tr)
WO (1) WO1999032455A1 (tr)

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JP7268049B2 (ja) 2018-03-08 2023-05-02 インサイト・コーポレイション ＰＩ３Ｋ－γ阻害剤としてのアミノピラジンジオール化合物
CN108484587A (zh) * 2018-06-03 2018-09-04 刘思良 一种Raf激酶抑制剂及其在癌症治疗中的应用
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AU2020329956B2 (en) 2019-08-12 2023-11-16 Deciphera Pharmaceuticals, Llc. Ripretinib for treating gastrointestinal stromal tumors
TW202122082A (zh) 2019-08-12 2021-06-16 美商迪賽孚爾製藥有限公司 治療胃腸道基質瘤方法
JP2023509628A (ja) 2019-12-30 2023-03-09 デシフェラ・ファーマシューティカルズ，エルエルシー １－（４－ブロモ－５－（１－エチル－７－（メチルアミノ）－２－オキソ－１，２－ジヒドロ－１，６－ナフチリジン－３－イル）－２－フルオロフェニル）－３－フェニル尿素の組成物
BR112022013109A2 (pt) 2019-12-30 2022-09-06 Deciphera Pharmaceuticals Llc Formulações de inibidor de quinase amorfo e métodos de uso das mesmas
US11779572B1 (en) 2022-09-02 2023-10-10 Deciphera Pharmaceuticals, Llc Methods of treating gastrointestinal stromal tumors

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