JP2001526224A5 - - Google Patents
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- Publication number
- JP2001526224A5 JP2001526224A5 JP2000525105A JP2000525105A JP2001526224A5 JP 2001526224 A5 JP2001526224 A5 JP 2001526224A5 JP 2000525105 A JP2000525105 A JP 2000525105A JP 2000525105 A JP2000525105 A JP 2000525105A JP 2001526224 A5 JP2001526224 A5 JP 2001526224A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cancer
- fpt inhibitor
- substituted
- proliferative disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99602797A | 1997-12-22 | 1997-12-22 | |
| US08/996,027 | 1997-12-22 | ||
| US14352998A | 1998-08-28 | 1998-08-28 | |
| US09/143,529 | 1998-08-28 | ||
| US18196998A | 1998-10-29 | 1998-10-29 | |
| US09/181,969 | 1998-10-29 | ||
| PCT/US1998/026224 WO1999032114A1 (en) | 1997-12-22 | 1998-12-21 | Combination of benzocycloheptapyridine compounds and antineoplastic drugs for treating proliferative diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001526224A JP2001526224A (ja) | 2001-12-18 |
| JP2001526224A5 true JP2001526224A5 (OSRAM) | 2006-02-09 |
| JP4502503B2 JP4502503B2 (ja) | 2010-07-14 |
Family
ID=27385940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000525105A Expired - Fee Related JP4502503B2 (ja) | 1997-12-22 | 1998-12-21 | 増殖性の疾患を処置するためのベンゾシクロヘプタピリジン化合物および抗腫瘍剤の組合せ |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP1041985B1 (OSRAM) |
| JP (1) | JP4502503B2 (OSRAM) |
| KR (1) | KR100700907B1 (OSRAM) |
| CN (1) | CN1129431C (OSRAM) |
| AR (1) | AR017440A1 (OSRAM) |
| AT (1) | ATE317697T1 (OSRAM) |
| AU (1) | AU756762B2 (OSRAM) |
| BR (1) | BR9814419A (OSRAM) |
| CA (1) | CA2315693C (OSRAM) |
| CL (1) | CL2007001889A1 (OSRAM) |
| CO (1) | CO5080764A1 (OSRAM) |
| CZ (1) | CZ298511B6 (OSRAM) |
| DE (1) | DE69833509T2 (OSRAM) |
| DK (1) | DK1041985T3 (OSRAM) |
| ES (1) | ES2255196T3 (OSRAM) |
| HU (1) | HUP0102473A3 (OSRAM) |
| IL (1) | IL136462A0 (OSRAM) |
| MY (1) | MY137303A (OSRAM) |
| NO (1) | NO326832B1 (OSRAM) |
| NZ (1) | NZ504928A (OSRAM) |
| PE (1) | PE20000042A1 (OSRAM) |
| PT (1) | PT1041985E (OSRAM) |
| SK (1) | SK285584B6 (OSRAM) |
| TW (1) | TW581763B (OSRAM) |
| WO (1) | WO1999032114A1 (OSRAM) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787327B1 (fr) * | 1998-12-21 | 2003-01-17 | Aventis Pharma Sa | Compositions contenant des inhibiteurs de farnesyle transferase |
| AU1400401A (en) * | 1999-11-09 | 2001-06-06 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Product inhibiting transduction of G heterotrimeric protein signals combined with another anti-cancer agent for therapeutic use in cancer treatment |
| AU2292801A (en) * | 1999-12-22 | 2001-07-03 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Compositions and methods for treatment of breast cancer |
| EP1261348A2 (en) * | 2000-02-29 | 2002-12-04 | Janssen Pharmaceutica N.V. | Combinations of a farnesyl protein transferase inhibitor with nitrogen mustard or nitrosourea alkylating agents |
| CA2397657A1 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica Inc. | Farnesyl protein transferase inhibitor combinations with platinum compounds |
| CA2397253A1 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor anthracycline derivatives |
| CA2397475A1 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with vinca alkaloids |
| AU2001239275A1 (en) * | 2000-02-29 | 2001-09-12 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor podophyllotoxin derivatives |
| WO2001064195A2 (en) * | 2000-02-29 | 2001-09-07 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with anti-tumor nucleoside derivatives |
| TWI310684B (en) | 2000-03-27 | 2009-06-11 | Bristol Myers Squibb Co | Synergistic pharmaceutical kits for treating cancer |
| AU2002236813A1 (en) * | 2001-01-22 | 2002-07-30 | Schering Corporation | Treatment of malaria with farnesyl protein transferase inhibitors |
| ES2318000T3 (es) * | 2001-02-15 | 2009-05-01 | Janssen Pharmaceutica Nv | Combinaciones de inhibidores de la farnesil-protein-transferasa con agentes antiestrogenos. |
| HUP0402401A2 (hu) * | 2001-11-30 | 2005-03-29 | Schering Corp. | Rák kezelésére szolgáló eljárások egy FPT inhibitor és daganatellenes szerek felhasználásával |
| EP1453513A1 (en) * | 2001-12-03 | 2004-09-08 | Schering Corporation | Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer |
| WO2008022535A1 (fr) * | 2006-08-09 | 2008-02-28 | Tian Jin Tasly Group Co., Ltd. | Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique |
| CN105198758A (zh) * | 2015-09-22 | 2015-12-30 | 湖南大学 | 一种高纯度(z)-他莫昔酚的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| DE69120430D1 (de) * | 1990-12-18 | 1996-07-25 | Wellcome Found | Mittel zur verstaerkung der wirkung von antitumoralen mittel und zur widerstandsbekaempfung von vielfachdrogen |
| JP2767176B2 (ja) * | 1992-12-15 | 1998-06-18 | 大塚製薬株式会社 | 抗癌剤 |
| US5637688A (en) * | 1994-12-13 | 1997-06-10 | Eli Lilly And Company | Process for preparing 1-(2'-deoxy-2'-difluoro-d-ribofuranosyl)-4-aminopyrimidin-2-one hydrochloride |
| WO1997005902A1 (fr) * | 1995-08-09 | 1997-02-20 | Banyu Pharmaceutical Co., Ltd. | Composition medicinale |
| CZ292791B6 (cs) * | 1995-12-22 | 2003-12-17 | Schering Corporation | Tricyklické amidy, které se používají pro inhibici G-proteinové funkce a k léčení proliferativních onemocnění |
| US5977163A (en) * | 1996-03-12 | 1999-11-02 | Pg-Txl Company, L. P. | Water soluble paclitaxel prodrugs |
| AU715604B2 (en) * | 1996-04-03 | 2000-02-03 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| JP2000508661A (ja) * | 1996-04-15 | 2000-07-11 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | 放射線および化学療法に対する細胞の感作 |
| WO1997038664A2 (en) * | 1996-04-18 | 1997-10-23 | Merck & Co., Inc. | A method of treating cancer |
| EP0934270A1 (en) * | 1996-05-30 | 1999-08-11 | Merck & Co., Inc. | A method of treating cancer |
| US6337992B1 (en) * | 1997-01-29 | 2002-01-08 | Philips Medical Systems Technologies Ltd. | Predictive bolus tracking |
| HUP0004326A3 (en) * | 1997-02-18 | 2003-07-28 | Canji Inc San Diego | Combined tumor suppressor gene therapy and chemotherapy in the treatment of neoplasms |
-
1998
- 1998-12-21 BR BR9814419-7A patent/BR9814419A/pt not_active Application Discontinuation
- 1998-12-21 CZ CZ20002236A patent/CZ298511B6/cs not_active IP Right Cessation
- 1998-12-21 AR ARP980106565A patent/AR017440A1/es unknown
- 1998-12-21 PE PE1998001263A patent/PE20000042A1/es not_active Application Discontinuation
- 1998-12-21 CA CA2315693A patent/CA2315693C/en not_active Expired - Fee Related
- 1998-12-21 AT AT98963829T patent/ATE317697T1/de not_active IP Right Cessation
- 1998-12-21 PT PT98963829T patent/PT1041985E/pt unknown
- 1998-12-21 CO CO98075842A patent/CO5080764A1/es unknown
- 1998-12-21 SK SK898-2000A patent/SK285584B6/sk not_active IP Right Cessation
- 1998-12-21 EP EP98963829A patent/EP1041985B1/en not_active Expired - Lifetime
- 1998-12-21 HU HU0102473A patent/HUP0102473A3/hu unknown
- 1998-12-21 JP JP2000525105A patent/JP4502503B2/ja not_active Expired - Fee Related
- 1998-12-21 TW TW087121355A patent/TW581763B/zh not_active IP Right Cessation
- 1998-12-21 DK DK98963829T patent/DK1041985T3/da active
- 1998-12-21 NZ NZ504928A patent/NZ504928A/xx unknown
- 1998-12-21 WO PCT/US1998/026224 patent/WO1999032114A1/en not_active Ceased
- 1998-12-21 KR KR1020007006938A patent/KR100700907B1/ko not_active Expired - Fee Related
- 1998-12-21 MY MYPI98005809A patent/MY137303A/en unknown
- 1998-12-21 ES ES98963829T patent/ES2255196T3/es not_active Expired - Lifetime
- 1998-12-21 AU AU19072/99A patent/AU756762B2/en not_active Ceased
- 1998-12-21 CN CN98813742A patent/CN1129431C/zh not_active Expired - Fee Related
- 1998-12-21 DE DE69833509T patent/DE69833509T2/de not_active Expired - Lifetime
- 1998-12-21 IL IL13646298A patent/IL136462A0/xx unknown
-
2000
- 2000-06-21 NO NO20003229A patent/NO326832B1/no not_active IP Right Cessation
-
2007
- 2007-06-27 CL CL2007001889A patent/CL2007001889A1/es unknown
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