|
ATE332127T1
(de)
*
|
1994-11-08 |
2006-07-15 |
Avicena Group Inc |
Verwendung von kreatin oder kreatinanologen zur behandlung von huntington chorea, morbus parkinson und amyotrophen lateralsklerose
|
|
US20050245612A1
(en)
*
|
2004-05-03 |
2005-11-03 |
Blass John P |
Pharmaceutical compositions for metabolic insufficiencies
|
|
US20060128671A1
(en)
*
|
1998-04-02 |
2006-06-15 |
The General Hospital Corporation |
Compositions containing a combination of a creatine compound and a second agent
|
|
WO1999051097A1
(en)
*
|
1998-04-02 |
1999-10-14 |
Avicena Group, Inc. |
Compositions containing a combination of a creatine compound and a second agent
|
|
DE19853487A1
(de)
|
1998-11-19 |
2000-05-25 |
Fumapharm Ag Muri |
Verwendung von Dialkylfumaraten
|
|
DE19932197A1
(de)
*
|
1999-07-09 |
2001-01-18 |
Neudecker Birgit |
Topisch anzuwendendes Mittel mit schützender und regenerativer Wirkung
|
|
US6689753B1
(en)
*
|
1999-11-05 |
2004-02-10 |
Axonyx, Inc. |
β sheet breaker peptide analogs that inhibit β pleated sheet formation in amyloid β-peptide
|
|
DE10000577A1
(de)
*
|
2000-01-10 |
2001-07-26 |
Fumapharm Ag Muri |
Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
|
|
GB2348371B
(en)
*
|
2000-03-14 |
2001-04-04 |
Soares Da Silva Patricio |
Compositions comprising blockers of L-DOPA renal cell transfer for the treatment of Parkinson's disease
|
|
US7208180B2
(en)
|
2000-05-08 |
2007-04-24 |
N.V. Nutricia |
Method and preparation for the preventing and/or treating vascular disorders and secondary disorders associated therewith
|
|
US7226916B1
(en)
|
2000-05-08 |
2007-06-05 |
N.V. Nutricia |
Preparation for the prevention and/or treatment of vascular disorders
|
|
US7157423B2
(en)
|
2001-01-12 |
2007-01-02 |
Fumapharm Ag |
Fumaric acid amides
|
|
UA76444C2
(en)
*
|
2001-02-14 |
2006-08-15 |
|
Composition of biochemical compounds involved in bioenergy metabolism of cells and method of its use in prevention and therapy of diseases
|
|
WO2003059387A2
(en)
*
|
2001-12-21 |
2003-07-24 |
Ilex Oncology, Inc. |
Combination comprising anti-cd52 antibodies and other therapeutic agents for treatment for multiple sclerosis
|
|
EP1475090A4
(en)
*
|
2002-02-14 |
2007-08-08 |
Ajinomoto Kk |
DRUG AGAINST MITOCHONDRIAL DISEASES
|
|
EP1820806A1
(en)
*
|
2006-02-16 |
2007-08-22 |
Crossbeta Biosciences B.V. |
Affinity regions
|
|
DE10217314A1
(de)
|
2002-04-18 |
2003-11-13 |
Fumapharm Ag Muri |
Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere
|
|
EP1567180A4
(en)
*
|
2002-06-04 |
2010-03-10 |
Avicena Group Inc |
METHOD FOR THE TREATMENT OF COGNITIVE DYSFUNCTION BY MODULATING THE CHANGE OF ENERGY REPLACEMENT IN THE BRAIN
|
|
US20070003552A1
(en)
*
|
2002-07-09 |
2007-01-04 |
Gebbink Martijn F B |
Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation
|
|
EP1380290A1
(en)
*
|
2002-07-09 |
2004-01-14 |
Universitair Medisch Centrum Utrecht |
Cross-beta structure pathway and its therapeutic relevance
|
|
AU2003247143B2
(en)
*
|
2002-08-01 |
2009-07-16 |
Yeda Research And Development Co. Ltd. |
Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels
|
|
US7977049B2
(en)
*
|
2002-08-09 |
2011-07-12 |
President And Fellows Of Harvard College |
Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
|
|
CA2499170A1
(en)
*
|
2002-09-27 |
2004-04-08 |
Children's Medical Center Corporation |
Methods and compositions for treatment of neurological disorder
|
|
RU2360671C2
(ru)
*
|
2003-07-01 |
2009-07-10 |
Эссентис Аб |
Применение альфа-кетоглутаровой кислоты для лечения недостаточности питания или состояния с высоким уровнем глюкозы в плазме
|
|
SE0301947D0
(sv)
*
|
2003-07-01 |
2003-07-01 |
Gramineer Internat Ab |
New method and uses
|
|
JP2007530417A
(ja)
*
|
2003-07-01 |
2007-11-01 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
細胞及び生物の寿命及びストレス応答を操作するための組成物
|
|
US20060025337A1
(en)
*
|
2003-07-01 |
2006-02-02 |
President And Fellows Of Harvard College |
Sirtuin related therapeutics and diagnostics for neurodegenerative diseases
|
|
CA2526586C
(en)
|
2003-09-09 |
2010-03-16 |
Biogen International Gmbh |
The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
|
|
US20050171027A1
(en)
|
2003-12-29 |
2005-08-04 |
President And Fellows Of Harvard College |
Compositions for treating or preventing obesity and insulin resistance disorders
|
|
US8017634B2
(en)
|
2003-12-29 |
2011-09-13 |
President And Fellows Of Harvard College |
Compositions for treating obesity and insulin resistance disorders
|
|
US20060084085A1
(en)
*
|
2004-06-16 |
2006-04-20 |
Sinclair David A |
Methods and compositions for modulating Bax-mediated apoptosis
|
|
PL368572A1
(en)
*
|
2004-06-17 |
2005-12-27 |
Sgp & Sons Ab |
Pharmaceutical compound for prevention and therapy of increased level of cholesterol, ldl and triglycerides as well as application of the pharmaceutical compound as an agent acting against atherosclerosis and used in circulatory system affections
|
|
US20060014705A1
(en)
*
|
2004-06-30 |
2006-01-19 |
Howitz Konrad T |
Compositions and methods for selectively activating human sirtuins
|
|
US20060024385A1
(en)
*
|
2004-07-27 |
2006-02-02 |
Pedersen Mark A |
Metabolic capacity enhancing compositions and methods for use in a mammal
|
|
PL369552A1
(pl)
*
|
2004-08-12 |
2006-02-20 |
Sgp & Sons Ab |
Preparat farmaceutyczny lub/i żywieniowy lub/i laboratoryjny wzmagający, wspomagający funkcjonowanie komórek nerwowych i układu nerwowego oraz zastosowanie preparatu farmaceutycznego lub/i żywieniowego w procesie ochrony funkcji układu nerwowego oraz zastosowanie preparatu do ochrony wzrostu stymulacji namnażania i zapobiegania apoptozie komórek nerwowych
|
|
WO2006025247A1
(ja)
*
|
2004-08-30 |
2006-03-09 |
Kaneka Corporation |
ミトコンドリア賦活剤
|
|
DK1824470T3
(da)
*
|
2004-12-17 |
2014-08-18 |
Cash Alan Brian |
Fremgangsmåde til forlængelse af levetiden og forsinke starttidspunktet for alders-relateret sygdom
|
|
JP2008524123A
(ja)
*
|
2004-12-21 |
2008-07-10 |
クリティカル ケア コネクションズ インク |
治療用栄養組成物又は組合せ、及びそれらの使用方法
|
|
EP1850840A2
(en)
*
|
2005-01-13 |
2007-11-07 |
Sirtris Pharmaceuticals, Inc. |
Novel compositions for preventing and treating neurodegenerative and blood coagulation disorders
|
|
AU2006239560B2
(en)
*
|
2005-04-28 |
2010-03-25 |
Unilever Plc |
Peptides having an ace inhibiting effect
|
|
WO2006138418A2
(en)
*
|
2005-06-14 |
2006-12-28 |
President And Fellows Of Harvard College |
Improvement of cognitive performance with sirtuin activators
|
|
US20070004639A1
(en)
*
|
2005-07-01 |
2007-01-04 |
Bodybio, Inc. |
Methods and compositions for treating Parkinson's disease
|
|
US20070149466A1
(en)
*
|
2005-07-07 |
2007-06-28 |
Michael Milburn |
Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
|
|
US20070015133A1
(en)
*
|
2005-07-13 |
2007-01-18 |
Umc Utrecht Holding B.V. |
Method for detecting and/or removing protein and/or peptide comprising a cross-beta structure from an aqueous solution comprising a protein
|
|
US8114832B2
(en)
*
|
2005-07-13 |
2012-02-14 |
Crossbeta Biosciences B.V. |
Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
|
|
AU2006267176A1
(en)
*
|
2005-07-13 |
2007-01-18 |
Crossbeta Biosciences B.V. |
Cross-beta structure binding compounds
|
|
BRPI0613525A2
(pt)
*
|
2005-07-13 |
2011-05-31 |
Crossbeta Biosciences Bv |
métodos para produzir uma composição imunogênica, para melhorar a imunogenicidade de uma composição, para intensificar a imunogenicidade de uma composição de vacina, e para determinar a quantidade de estruturas beta-cruzadas em uma composição de vacina, usos de estruturas beta-cruzadas, e de uma composição imunogênica, vacina de subunidade, e, composição imunogênica
|
|
JP2007023010A
(ja)
*
|
2005-07-19 |
2007-02-01 |
Toshiro Azegami |
閉経後のホルモンバランス調整及びパーキンソン症の予防改善目的の経口組成物
|
|
DE102005035917A1
(de)
*
|
2005-07-28 |
2007-02-01 |
November Ag |
Verwendung von Isocitrat, Isocitronensäure oder einem Derivat davon zur Herstellung eines Medikaments
|
|
DK1909600T3
(da)
*
|
2005-07-29 |
2012-07-30 |
Tima Foundation |
Sammensætning til moderering af alkoholmetabolisme og til at reducere risikoen for alkoholforårsagede sygdomme
|
|
AU2007249847A1
(en)
*
|
2006-05-11 |
2007-11-22 |
Avicena Group, Inc. |
Methods of treating a neurological disorder with creatine monohydrate
|
|
US8435547B2
(en)
*
|
2006-08-30 |
2013-05-07 |
John P. Blass |
Cream for stimulating mitochondrial activity in the skin
|
|
ES2599227T3
(es)
*
|
2007-02-08 |
2017-01-31 |
Biogen Ma Inc. |
Neuroprotección en enfermedades desmielinizantes
|
|
EP2680010A1
(en)
|
2007-02-08 |
2014-01-01 |
Biogen Idec MA Inc. |
Nrf2 screening assays and related methods and compositions
|
|
EP2058000A1
(en)
*
|
2007-11-08 |
2009-05-13 |
Crossbeta Biosciences B.V. |
Immunogenic compositions capable of activating T cells
|
|
EP2058001A1
(en)
*
|
2007-11-08 |
2009-05-13 |
Crossbeta Biosciences B.V. |
Enhancement of immunogenicity of antigens
|
|
US20090269796A1
(en)
*
|
2007-12-05 |
2009-10-29 |
The General Hospital Corporation |
Methods of detecting and treating myocardial ischemia and myocardial infarction
|
|
WO2010033045A1
(en)
*
|
2008-09-16 |
2010-03-25 |
Igor Anatolievich Pomytkin |
Compositions and methods for prevention or treatment of beta amyloid deposition
|
|
US9233099B2
(en)
|
2012-01-11 |
2016-01-12 |
University Of Cincinnati |
Methods of treating cognitive dysfunction by modulating brain energy metabolism
|
|
CA2884592C
(en)
|
2012-09-19 |
2021-08-31 |
Grespo Ab |
Compositions for improvement of brain function
|
|
US20140243400A1
(en)
*
|
2013-02-28 |
2014-08-28 |
University of Alaska Anchorage |
Compositions comprising citric acid and malic acid and methods and uses thereof
|
|
WO2014160423A1
(en)
|
2013-03-13 |
2014-10-02 |
Genetic Disease Investigators, LLC |
Methods and compositions for correction of organ dysfunction
|
|
US10238673B2
(en)
|
2013-03-13 |
2019-03-26 |
Genetic Disease Investigators, LLC |
Methods and compositions for treatment of dry eye and correction of organ dysfunctions
|
|
GB201411937D0
(en)
|
2014-07-03 |
2014-08-20 |
Medical Res Council |
Succinate dehydrogenase inhibitors (SDH's)
|
|
JP6831558B2
(ja)
*
|
2016-08-23 |
2021-02-17 |
株式会社Hbcフナト |
脳機能改善組成物
|
|
US11071722B2
(en)
*
|
2016-09-22 |
2021-07-27 |
Alan B. Cash |
Method to alleviate the symptoms of PMS
|
|
JP6129395B1
(ja)
*
|
2016-10-29 |
2017-05-17 |
誠一 荒木 |
ミトコンドリア活性化に起因した血管内皮細胞保護回復用還元型ビタミンb2製剤
|
|
IT201700087359A1
(it)
*
|
2017-07-28 |
2019-01-28 |
Professional Dietetics Spa |
Composizioni comprendenti amino acidi per l'uso nel trattamento di malattie associate a disfunzione mitocondriale
|
|
IT201800006725A1
(it)
*
|
2018-06-27 |
2019-12-27 |
|
Composizioni comprendenti aminoacidi per l'uso nella prevenzione e nel trattamento di malattie epatiche
|
|
CA3113071A1
(en)
*
|
2018-10-11 |
2020-04-16 |
Imbria Pharmaceuticals, Inc. |
Tca cycle intermediates and methods of use thereof
|
|
WO2020086733A1
(en)
*
|
2018-10-24 |
2020-04-30 |
Ponce De Leon Health Designated Activity Company |
Nicotinamide riboside compositions for healthspan extension
|
|
IT201900002109A1
(it)
|
2019-02-13 |
2020-08-13 |
Professional Dietetics Spa |
Composizioni comprendenti amminoacidi per l'uso nel trattamento di lesioni del sistema nervoso centrale
|
|
IT202000000442A1
(it)
|
2020-01-13 |
2021-07-13 |
Professional Dietetics Spa |
Composizioni comprendenti amino acidi per l'uso nella prevenzione e nel trattamento di effetti collaterali della chemioterapia
|
|
CN114794009A
(zh)
*
|
2021-02-05 |
2022-07-29 |
崔德斌 |
一种用于动物模型中诱导癌症的组合物及其用途
|
|
CN115212195B
(zh)
*
|
2022-06-17 |
2024-02-27 |
重庆医科大学 |
苹果酸在制备预防和/或治疗抑郁症的药物中的用途
|
|
US20250221952A1
(en)
*
|
2025-03-14 |
2025-07-10 |
Louis Dischler |
Methods and compositions for large modifications of atp output by inner mitochondrial membrane latching
|