JP2001517636A - ビタミンｋ依存性単一因子を含む医薬調製物 - Google Patents

ビタミンｋ依存性単一因子を含む医薬調製物

Info

Publication number
JP2001517636A
JP2001517636A JP2000512565A JP2000512565A JP2001517636A JP 2001517636 A JP2001517636 A JP 2001517636A JP 2000512565 A JP2000512565 A JP 2000512565A JP 2000512565 A JP2000512565 A JP 2000512565A JP 2001517636 A JP2001517636 A JP 2001517636A
Authority
JP
Japan
Prior art keywords
factor
preparation
protein
preparation according
factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000512565A
Other languages
English (en)
Japanese (ja)
Inventor
イェンドラ・リンナウ
ペーター・トゥレツェック
ハンス−ペーター・シュヴァルツ
Original Assignee
バクスター・アクチエンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バクスター・アクチエンゲゼルシャフト filed Critical バクスター・アクチエンゲゼルシャフト
Publication of JP2001517636A publication Critical patent/JP2001517636A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2000512565A 1997-09-19 1998-09-17 ビタミンｋ依存性単一因子を含む医薬調製物 Pending JP2001517636A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0159197A AT409334B (de) 1997-09-19 1997-09-19 Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren
AT1591/97 1997-09-19
PCT/AT1998/000224 WO1999015196A1 (de) 1997-09-19 1998-09-17 Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren

Publications (1)

Publication Number Publication Date
JP2001517636A true JP2001517636A (ja) 2001-10-09

Family

ID=3516739

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000512565A Pending JP2001517636A (ja) 1997-09-19 1998-09-17 ビタミンｋ依存性単一因子を含む医薬調製物

Country Status (10)

Country Link
EP (1) EP1015020A1 (pt)
JP (1) JP2001517636A (pt)
AT (1) AT409334B (pt)
AU (1) AU743102B2 (pt)
BR (1) BR9812222A (pt)
CA (1) CA2304396A1 (pt)
HU (1) HUP0003681A1 (pt)
NO (1) NO20001415L (pt)
SK (1) SK4022000A3 (pt)
WO (1) WO1999015196A1 (pt)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013538863A (ja) * 2010-10-06 2013-10-17 メドイミューン・リミテッド 止血障害治療用第ｉｉ因子およびフィブリノーゲン
JP2020506880A (ja) * 2017-02-09 2020-03-05 ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー 出血の処置または予防における使用のための血液凝固因子代替製品

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002351756A1 (en) 2001-12-21 2003-07-15 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
JP2005528351A (ja) * 2002-03-08 2005-09-22 イーライ・リリー・アンド・カンパニー 活性化プロテインｃ製剤
CA2490342C (en) 2002-06-21 2015-06-16 Novo Nordisk A/S Stabilised solid compositions of factor vii polypeptides
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
CA2525224A1 (en) 2003-05-23 2004-12-02 Michael Bech Jensen Protein stabilization in solution
EP1641487B1 (en) 2003-06-25 2012-02-29 Novo Nordisk Health Care AG Liquid composition of factor vii polypeptides
BRPI0413518A (pt) 2003-08-14 2006-10-10 Novo Nordisk Healthcare Ag composição farmacêutica lìquida aquosa, método para preparar e uso da mesma, método para tratar uma sìndrome responsiva ao fator vii, e, recipiente hermético
DK2298287T3 (en) 2003-12-19 2018-07-23 Novo Nordisk Healthcare Ag Stabilized compositions of factor VII polypeptides
JP2008530208A (ja) * 2005-02-16 2008-08-07 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ 万能前凝固薬
EP1869082B1 (en) 2005-03-04 2011-04-13 The Board Of Trustees Of The University Of Illinois Coagulation and fibrinolytic cascades modulator
WO2009046194A2 (en) 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
US20100297257A1 (en) 2007-11-09 2010-11-25 National Institutes Of Health (Nih), U.S. Dept. Of Health And Human Services (Dhhs) Anticoagulant antagonist and hemophillia procoagulant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729822D0 (en) * 1987-12-22 1988-02-03 Central Blood Lab Authority Chemical process
IT1262899B (it) * 1992-03-27 1996-07-22 Sclavo Spa Processo per l'isolamento di fattore ix, fattore x e fattore ii altamente purificati dal complesso protrombinico o dal plasma umano
DE4342132C1 (de) * 1993-12-10 1994-11-03 Octapharma Ag Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie
DE4430205A1 (de) * 1994-08-26 1996-02-29 Behringwerke Ag Zusammensetzungen, die als Gegenmittel für Blut-Antikoagulanzien geeignet sind und deren Verwendung
DE59712322D1 (de) * 1996-03-20 2005-06-30 Baxter Ag Pharmazeutisches Präparat zur Behandlung von Blutgerinnungsstörungen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013538863A (ja) * 2010-10-06 2013-10-17 メドイミューン・リミテッド 止血障害治療用第ｉｉ因子およびフィブリノーゲン
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
JP2020506880A (ja) * 2017-02-09 2020-03-05 ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー 出血の処置または予防における使用のための血液凝固因子代替製品
JP7227905B2 (ja) 2017-02-09 2023-02-22 ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー 出血の処置または予防における使用のための血液凝固因子代替製品

Also Published As

Publication number Publication date
BR9812222A (pt) 2000-07-18
SK4022000A3 (en) 2000-09-12
AU9244998A (en) 1999-04-12
WO1999015196A1 (de) 1999-04-01
HUP0003681A1 (hu) 2001-02-28
NO20001415L (no) 2000-05-19
AT409334B (de) 2002-07-25
AU743102B2 (en) 2002-01-17
CA2304396A1 (en) 1999-04-01
ATA159197A (de) 2001-12-15
NO20001415D0 (no) 2000-03-17
EP1015020A1 (de) 2000-07-05

Similar Documents

Publication Publication Date Title
US5866122A (en) Pharmaceutical preparation for treating blood coagulation disorders
US5457181A (en) Preparation of a high-purity human factor IX concentrate and other plasmatic proteins and their therapeutic use
US5336610A (en) Method for purification of the zymogen of protein C or the heavy chain thereof using monoclonal antibody HPC-4
JPS6254286B2 (pt)
US5478558A (en) Method of dissolving venous Thrombi using drug containing activated Protein C
JP2001527543A (ja) 活性化プロテインｃの改良プロセシング方法
JP2001517636A (ja) ビタミンｋ依存性単一因子を含む医薬調製物
US5219995A (en) Plasma fraction purification
AU4968390A (en) Monoclonal antibody against protein c
Michalski et al. Large‐scale production and properties of a solvent‐detergent‐treated factor IX concentrate from human plasma
JPH0193535A (ja) 線溶活性増強剤
RU2142806C1 (ru) Способ очистки и хранения фактора ix, водный раствор очищенного фактора ix, композиция, содержащая фактор ix, способ лечения
JPH1059866A (ja) 血液凝固第ｖｉｉ因子及び／もしくは活性化血液凝固第ｖｉｉ因子の製造方法
US6403556B1 (en) Pharmaceutical preparation containing protein C and a thrombolytically active substance
EP0139447A2 (en) A process for preparing urokinase zymogen
CA1170183A (en) Blood coagulation promoting product
US4614795A (en) Deglycosylated Human Factor VIII:C
JP2001506987A (ja) フォンビルブラント因子誘導体及びタンパク質の単離法
US20020019036A1 (en) Von willebrand factor derivatives and methods of isolating proteins that bind to von willebrand factor
MXPA00002622A (es) Preparado farmaceutico que contiene factores individuales dependientes de la vitamina k
CZ2000982A3 (cs) Farmaceutický preparát obsahující jednotlivé faktory, závislé na vitaminu K a jeho použití
JP2002515245A (ja) プロテインｚ依存性プロテアーゼインヒビター
JPH08291080A (ja) 過凝固または低線溶状態およびその類縁疾患の予防治療剤

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20051108

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20060404