JP2001517449A - ストレプトコッカス・ニューモニア由来のヒト補体c3分解プロテイナーゼ - Google Patents

ストレプトコッカス・ニューモニア由来のヒト補体c3分解プロテイナーゼ

Info

Publication number
JP2001517449A
JP2001517449A JP2000512965A JP2000512965A JP2001517449A JP 2001517449 A JP2001517449 A JP 2001517449A JP 2000512965 A JP2000512965 A JP 2000512965A JP 2000512965 A JP2000512965 A JP 2000512965A JP 2001517449 A JP2001517449 A JP 2001517449A
Authority
JP
Japan
Prior art keywords
protein
seq
nucleic acid
isolated
pneumonia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000512965A
Other languages
English (en)
Japanese (ja)
Inventor
ケー. ホステッター,マーガレット
ジェイ. フィンケル,デビット
チェン,クィ
エー. グリーン,ブルース
ダブリュ. マサイ,エイミー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota
Original Assignee
University of Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Minnesota filed Critical University of Minnesota
Publication of JP2001517449A publication Critical patent/JP2001517449A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2000512965A 1997-09-24 1998-09-24 ストレプトコッカス・ニューモニア由来のヒト補体c3分解プロテイナーゼ Pending JP2001517449A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5990797P 1997-09-24 1997-09-24
US60/059,907 1997-09-24
PCT/US1998/020186 WO1999015675A1 (en) 1997-09-24 1998-09-24 HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE)

Publications (1)

Publication Number Publication Date
JP2001517449A true JP2001517449A (ja) 2001-10-09

Family

ID=22026061

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000512965A Pending JP2001517449A (ja) 1997-09-24 1998-09-24 ストレプトコッカス・ニューモニア由来のヒト補体c3分解プロテイナーゼ

Country Status (8)

Country Link
EP (1) EP1017828A1 (de)
JP (1) JP2001517449A (de)
KR (1) KR20010024299A (de)
CN (1) CN1291233A (de)
AU (1) AU9510598A (de)
BR (1) BR9812525A (de)
CA (1) CA2305016A1 (de)
WO (1) WO1999015675A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009512451A (ja) * 2005-10-21 2009-03-26 カタリスト・バイオサイエンシーズ・インコーポレイテッド 補体活性化を阻害する修飾プロテアーゼ

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
EP0941335A2 (de) 1996-10-31 1999-09-15 Human Genome Sciences Polynukleotide und sequenzen aus streptococcus pneumoniae
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
US6936252B2 (en) 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
EP1790730A3 (de) * 1998-07-27 2007-09-12 Sanofi Pasteur Limited Pneumokokkenproteine und Nukleinsäuremoleküle
IL142017A0 (en) * 1998-09-24 2002-03-10 Univ Minnesota Human complement c3-degrading polypeptide from streptococcus pneumoniae
JP4689044B2 (ja) 1998-12-21 2011-05-25 メディミューン,インコーポレーテッド ワクチン用の肺炎連鎖球菌タンパク質と免疫原断片
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
EP1950302B1 (de) * 1998-12-23 2012-12-05 ID Biomedical Corporation of Quebec Streptokokken-Antigene
KR100802198B1 (ko) * 1998-12-23 2008-02-11 샤이어 바이오켐 인코포레이티드 신규한 스트렙토코커스 항원
AU2005209689B2 (en) * 1998-12-23 2008-07-17 Id Biomedical Corporation Of Quebec Novel streptococcus antigens
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
WO2001098334A2 (en) * 2000-06-20 2001-12-27 Shire Biochem Inc. Streptococcus antigens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
ES2359625T3 (es) * 2000-12-28 2011-05-25 Wyeth Llc Proteina protectora recombinante de.
AU2002351623A1 (en) 2001-12-20 2003-07-09 Shire Biochem Inc. Streptococcus antigens
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
CA2808919C (en) 2005-12-22 2016-04-19 Glaxosmithkline Biologicals S.A. Streptococcus pneumoniae capsular saccharide vaccine
EP2687228B1 (de) 2007-06-26 2017-07-19 GlaxoSmithKline Biologicals S.A. Impfstoff mit streptococcus pneumoniae-kapsulären polysaccharid-konjugaten
KR20110009157A (ko) 2008-04-16 2011-01-27 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
US20140072622A1 (en) 2011-05-17 2014-03-13 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
CN102731739B (zh) * 2012-07-05 2013-11-06 富阳经略化工技术有限公司 用作润滑油粘度指数改进剂的星形聚合物及其制备方法和应用
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0941335A2 (de) * 1996-10-31 1999-09-15 Human Genome Sciences Polynukleotide und sequenzen aus streptococcus pneumoniae
JP2001523960A (ja) * 1997-04-24 2001-11-27 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ ストレプトコッカス・ニゥモニエからのヒト補体c3分解性プロテイナーゼ

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009512451A (ja) * 2005-10-21 2009-03-26 カタリスト・バイオサイエンシーズ・インコーポレイテッド 補体活性化を阻害する修飾プロテアーゼ
JP2013013420A (ja) * 2005-10-21 2013-01-24 Catalyst Biosciences Inc 補体活性化を阻害する修飾プロテアーゼ
US9795655B2 (en) 2005-10-21 2017-10-24 Catalyst Biosciences, Inc. Modified MT-SP1 proteases that inhibit complement activation

Also Published As

Publication number Publication date
KR20010024299A (ko) 2001-03-26
CA2305016A1 (en) 1999-04-01
WO1999015675A1 (en) 1999-04-01
BR9812525A (pt) 2000-07-25
CN1291233A (zh) 2001-04-11
AU9510598A (en) 1999-04-12
EP1017828A1 (de) 2000-07-12

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