BR9812525A - Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae - Google Patents

Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae

Info

Publication number
BR9812525A
BR9812525A BR9812525-7A BR9812525A BR9812525A BR 9812525 A BR9812525 A BR 9812525A BR 9812525 A BR9812525 A BR 9812525A BR 9812525 A BR9812525 A BR 9812525A
Authority
BR
Brazil
Prior art keywords
human complement
proteinase
streptococcus pneumoniae
degrading
degrading proteinase
Prior art date
Application number
BR9812525-7A
Other languages
English (en)
Inventor
Margaret K Hostetter
David J Finkel
Qi Cheng
Bruce A Green
Amy W Masi
Original Assignee
Univ Minnesota
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota, American Cyanamid Co filed Critical Univ Minnesota
Publication of BR9812525A publication Critical patent/BR9812525A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Patente de Invenção: <B>"PROTEINASE DEGRADADORA DE COMPLEMENTO HUMANO C3 DE STREPTOCOCCUS PNEUMONIAE"<D>. A presente invenção refere-se à identificação e ao uso de uma família de proteinases degradadoras de complemento humano C3, expressadas por S. pneumoniae. A proteinase tem um peso molecular de cerca de 15 kDa a cerca de 25 kDa. Uma proteinase preferida desta invenção inclui a seq³ência de aminoácidos de SEQ ID NO: 2.
BR9812525-7A 1997-09-24 1998-09-24 Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae BR9812525A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5990797P 1997-09-24 1997-09-24
PCT/US1998/020186 WO1999015675A1 (en) 1997-09-24 1998-09-24 HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE)

Publications (1)

Publication Number Publication Date
BR9812525A true BR9812525A (pt) 2000-07-25

Family

ID=22026061

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812525-7A BR9812525A (pt) 1997-09-24 1998-09-24 Proteinase degradadora de complemento humano c3 de streptococcus pneumoniae

Country Status (8)

Country Link
EP (1) EP1017828A1 (pt)
JP (1) JP2001517449A (pt)
KR (1) KR20010024299A (pt)
CN (1) CN1291233A (pt)
AU (1) AU9510598A (pt)
BR (1) BR9812525A (pt)
CA (1) CA2305016A1 (pt)
WO (1) WO1999015675A1 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245335B1 (en) 1996-05-01 2001-06-12 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
DE69737125T3 (de) 1996-10-31 2015-02-26 Human Genome Sciences, Inc. Streptococcus pneumoniae-Antigene und Impfstoffe
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
EP1790729A3 (en) * 1998-07-27 2007-07-25 Sanofi Pasteur Limited Streptococcus pneumoniae proteins and nucleic acid molecules
US6936252B2 (en) 1998-07-27 2005-08-30 Microbial Technics Limited Streptococcus pneumoniae proteins and nucleic acid molecules
EP1115875A1 (en) * 1998-09-24 2001-07-18 Regents Of The University Of Minnesota Human complement c3-degrading polypeptide from streptococcus pneumoniae
ATE422899T1 (de) 1998-12-21 2009-03-15 Medimmune Inc Streptococcus pneumoniae proteine und immunogene fragmente für impstoffe
AU2005209689B2 (en) * 1998-12-23 2008-07-17 Id Biomedical Corporation Of Quebec Novel streptococcus antigens
TR200200633T2 (tr) * 1998-12-23 2002-06-21 Shire Biochem Inc. Yeni streptococcus antijenleri
US7128918B1 (en) 1998-12-23 2006-10-31 Id Biomedical Corporation Streptococcus antigens
EP1950302B1 (en) * 1998-12-23 2012-12-05 ID Biomedical Corporation of Quebec Streptococcus antigens
CA2413450C (en) * 2000-06-20 2014-02-18 Shire Biochem Inc. Streptococcus antigens
US7074415B2 (en) 2000-06-20 2006-07-11 Id Biomedical Corporation Streptococcus antigens
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
EP1355918B9 (en) * 2000-12-28 2012-01-25 Wyeth LLC Recombinant protective protein from $i(streptococcus pneumoniae)
US7262024B2 (en) 2001-12-20 2007-08-28 Id Biomedical Corporation Streptococcus antigens
WO2007047995A2 (en) * 2005-10-21 2007-04-26 Catalyst Biosciences, Inc. Modified proteases that inhibit complement activation
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
EP3020411A1 (en) 2005-12-22 2016-05-18 GlaxoSmithKline Biologicals s.a. Vaccine
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
WO2009000825A2 (en) 2007-06-26 2008-12-31 Glaxosmithkline Biologicals S.A. Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
EA201001479A1 (ru) 2008-04-16 2011-06-30 Глаксосмитклайн Байолоджикалс С.А. Вакцина
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
GB201003920D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Method of treatment
WO2012156391A1 (en) 2011-05-17 2012-11-22 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae
CN102731739B (zh) * 2012-07-05 2013-11-06 富阳经略化工技术有限公司 用作润滑油粘度指数改进剂的星形聚合物及其制备方法和应用
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69737125T3 (de) * 1996-10-31 2015-02-26 Human Genome Sciences, Inc. Streptococcus pneumoniae-Antigene und Impfstoffe
CN1253589A (zh) * 1997-04-24 2000-05-17 美国明尼苏达州大学 来自肺炎链球菌的降解人类补体c3的蛋白酶

Also Published As

Publication number Publication date
KR20010024299A (ko) 2001-03-26
EP1017828A1 (en) 2000-07-12
WO1999015675A1 (en) 1999-04-01
AU9510598A (en) 1999-04-12
CN1291233A (zh) 2001-04-11
CA2305016A1 (en) 1999-04-01
JP2001517449A (ja) 2001-10-09

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]