BR9809405A - Proteinase de streptococcus pneumoniae que degrada complemento humano c3 - Google Patents

Proteinase de streptococcus pneumoniae que degrada complemento humano c3

Info

Publication number
BR9809405A
BR9809405A BR9809405-0A BR9809405A BR9809405A BR 9809405 A BR9809405 A BR 9809405A BR 9809405 A BR9809405 A BR 9809405A BR 9809405 A BR9809405 A BR 9809405A
Authority
BR
Brazil
Prior art keywords
proteinase
human complement
streptococcus pneumoniae
degrades human
pneumoniae
Prior art date
Application number
BR9809405-0A
Other languages
English (en)
Inventor
Margaret K Hostetter
Gary Dunny
Lakshmi S Nandiwada
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of BR9809405A publication Critical patent/BR9809405A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Abstract

Patente de Invenção:<B>"PROTEINASE DE STREPTOCOCCUS PNEUMONIAE QUE DEGRADA COMPLEMENTO HUMANO C3"<D>. A presente invenção refere-se à identificação e uso de uma família de proteinases que degradam complemento humano C3 expressas por S. pneumoniae. A proteinase possui um peso molecular de cerca de 24 kD a cerca de 34 kD conforme determinado em um gel de SDS poliacrilamida a 10%. A proteinase preferida desta invenção inclui a seq³ência de aminoácidos de SEQ ID NO: 2.
BR9809405-0A 1997-04-24 1998-04-24 Proteinase de streptococcus pneumoniae que degrada complemento humano c3 BR9809405A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4431697P 1997-04-24 1997-04-24
PCT/US1998/008281 WO1998048022A1 (en) 1997-04-24 1998-04-24 HUMAN COMPLEMENT C3-DEGRADING PROTEINASE FROM $i(STREPTOCOCCUS PNEUMONIAE)

Publications (1)

Publication Number Publication Date
BR9809405A true BR9809405A (pt) 2000-06-13

Family

ID=21931691

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809405-0A BR9809405A (pt) 1997-04-24 1998-04-24 Proteinase de streptococcus pneumoniae que degrada complemento humano c3

Country Status (8)

Country Link
EP (1) EP0977872A1 (pt)
JP (1) JP2001523960A (pt)
KR (1) KR100544594B1 (pt)
CN (1) CN1253589A (pt)
AU (1) AU740153B2 (pt)
BR (1) BR9809405A (pt)
CA (1) CA2283755A1 (pt)
WO (1) WO1998048022A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676943B1 (en) 1997-04-24 2004-01-13 Regents Of The University Of Minnesota Human complement C3-degrading protein from Streptococcus pneumoniae
AU9510598A (en) * 1997-09-24 1999-04-12 American Cyanamid Company Human complement c3-degrading proteinase from (streptococcus pneumoniae)
EP1115875A1 (en) * 1998-09-24 2001-07-18 Regents Of The University Of Minnesota Human complement c3-degrading polypeptide from streptococcus pneumoniae

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1770164B1 (en) * 1996-10-31 2010-09-01 Human Genome Sciences, Inc. Streptococcus pneumoniae antigens and vaccines

Also Published As

Publication number Publication date
AU740153B2 (en) 2001-11-01
EP0977872A1 (en) 2000-02-09
KR20010012096A (ko) 2001-02-15
AU7156698A (en) 1998-11-13
WO1998048022A1 (en) 1998-10-29
JP2001523960A (ja) 2001-11-27
KR100544594B1 (ko) 2006-01-24
CA2283755A1 (en) 1998-10-29
WO1998048022A9 (en) 1999-04-15
CN1253589A (zh) 2000-05-17

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: O DEPOSITANTE DEIXOU DE APRESENTAR MANIFESTACAO SOBRE O PARECER NEGATIVO DE FOLHAS 77 A 81 PUBLICADO NA RPI N.O 1970, DE 07/10/2008. ASSIM, DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.