JP2001512329A - 生物活性薬剤送達のための組織微穿孔 - Google Patents

生物活性薬剤送達のための組織微穿孔

Info

Publication number
JP2001512329A
JP2001512329A JP53029898A JP53029898A JP2001512329A JP 2001512329 A JP2001512329 A JP 2001512329A JP 53029898 A JP53029898 A JP 53029898A JP 53029898 A JP53029898 A JP 53029898A JP 2001512329 A JP2001512329 A JP 2001512329A
Authority
JP
Japan
Prior art keywords
site
biological membrane
tissue
skin
energy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP53029898A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001512329A5 (enExample
Inventor
エイ. エプステイン,ジョナサン
Original Assignee
アルテア テクノロジーズ,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1997/011670 external-priority patent/WO1998000193A1/en
Application filed by アルテア テクノロジーズ,インコーポレイテッド filed Critical アルテア テクノロジーズ,インコーポレイテッド
Publication of JP2001512329A publication Critical patent/JP2001512329A/ja
Publication of JP2001512329A5 publication Critical patent/JP2001512329A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0047Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00137Details of operation mode
    • A61B2017/00154Details of operation mode pulsed
    • A61B2017/00172Pulse trains, bursts, intermittent continuous operation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Radiation-Therapy Devices (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Surgical Instruments (AREA)
  • Laser Surgery Devices (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
JP53029898A 1996-12-31 1997-12-30 生物活性薬剤送達のための組織微穿孔 Withdrawn JP2001512329A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77841596A 1996-12-31 1996-12-31
WO08/778,415 1997-07-03
WO97/11670 1997-07-03
PCT/US1997/011670 WO1998000193A1 (en) 1996-07-03 1997-07-03 Multiple mechanical microporation of skin or mucosa
PCT/US1997/024127 WO1998029134A2 (en) 1996-12-31 1997-12-30 Microporation of tissue for delivery of bioactive agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008157298A Division JP2008307391A (ja) 1996-12-31 2008-06-16 生物活性薬剤送達のための組織微穿孔

Publications (2)

Publication Number Publication Date
JP2001512329A true JP2001512329A (ja) 2001-08-21
JP2001512329A5 JP2001512329A5 (enExample) 2005-09-08

Family

ID=25113276

Family Applications (5)

Application Number Title Priority Date Filing Date
JP53029898A Withdrawn JP2001512329A (ja) 1996-12-31 1997-12-30 生物活性薬剤送達のための組織微穿孔
JP2008157298A Withdrawn JP2008307391A (ja) 1996-12-31 2008-06-16 生物活性薬剤送達のための組織微穿孔
JP2009203124A Withdrawn JP2010005425A (ja) 1996-12-31 2009-09-02 生物活性薬剤送達のための組織微穿孔
JP2013016445A Expired - Fee Related JP5657040B2 (ja) 1996-12-31 2013-01-31 生物体へ浸透性物質を送達するための、または、生物体から分析物を抽出するための装置
JP2013046499A Expired - Lifetime JP5680685B2 (ja) 1996-12-31 2013-03-08 生物活性薬剤送達のための組織微穿孔

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2008157298A Withdrawn JP2008307391A (ja) 1996-12-31 2008-06-16 生物活性薬剤送達のための組織微穿孔
JP2009203124A Withdrawn JP2010005425A (ja) 1996-12-31 2009-09-02 生物活性薬剤送達のための組織微穿孔
JP2013016445A Expired - Fee Related JP5657040B2 (ja) 1996-12-31 2013-01-31 生物体へ浸透性物質を送達するための、または、生物体から分析物を抽出するための装置
JP2013046499A Expired - Lifetime JP5680685B2 (ja) 1996-12-31 2013-03-08 生物活性薬剤送達のための組織微穿孔

Country Status (9)

Country Link
EP (2) EP1314400B1 (enExample)
JP (5) JP2001512329A (enExample)
AT (1) ATE365026T1 (enExample)
AU (1) AU5623298A (enExample)
CA (2) CA2789115C (enExample)
DE (1) DE69737836T2 (enExample)
DK (1) DK1314400T3 (enExample)
ES (1) ES2289192T3 (enExample)
WO (1) WO1998029134A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
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JP2005528137A (ja) * 2002-03-11 2005-09-22 アルテア セラピューティクス コーポレイション 経皮薬物送達パッチシステム、このシステムを作製する方法およびこのシステムを使用する方法
JP2010507627A (ja) * 2006-10-25 2010-03-11 パンテック バイオソリューションズ アクチェンゲゼルシャフト 皮膚に関連した症状の広域疑似全身的治療
US7854719B2 (en) 2006-01-06 2010-12-21 Kabushiki Kaisha Toshiba Method of introducing ultrasonic drug and apparatus thereof
JP2013500118A (ja) * 2009-07-30 2013-01-07 アルマ レーザー エルティーディー. ソノトロード
KR101232225B1 (ko) 2003-10-24 2013-02-12 알테아 쎄라퓨텍스 코포레이션 투과제를 생물학적 멤브레인으로 전달하는 장치

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AU3880697A (en) * 1996-07-03 1998-01-21 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US6517532B1 (en) 1997-05-15 2003-02-11 Palomar Medical Technologies, Inc. Light energy delivery head
US6527716B1 (en) 1997-12-30 2003-03-04 Altea Technologies, Inc. Microporation of tissue for delivery of bioactive agents
US6173202B1 (en) 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
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EP1645305A1 (en) 1999-06-08 2006-04-12 Altea Therapeutics Corporation Apparatus for microporation of biological membranes using thin film tissue interface devices, and method for manufacturing
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
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JP2013165967A (ja) 2013-08-29
EP1314400A3 (en) 2003-10-15
WO1998029134A3 (en) 1998-10-15
DE69737836T2 (de) 2008-03-06
CA2789115C (en) 2014-04-29
CA2789115A1 (en) 1998-07-09
ATE365026T1 (de) 2007-07-15
CA2276312C (en) 2012-11-27
JP5657040B2 (ja) 2015-01-21
EP1314400A2 (en) 2003-05-28
WO1998029134A2 (en) 1998-07-09
AU5623298A (en) 1998-07-31
JP2008307391A (ja) 2008-12-25
JP2010005425A (ja) 2010-01-14
DE69737836D1 (de) 2007-08-02
ES2289192T3 (es) 2008-02-01
CA2276312A1 (en) 1998-07-09
EP1314400B1 (en) 2007-06-20
JP5680685B2 (ja) 2015-03-04

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