DE69737836T2 - Mikroporation von Gewebe zur Verabreichung von bioaktiven Substanzen - Google Patents
Mikroporation von Gewebe zur Verabreichung von bioaktiven Substanzen Download PDFInfo
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- DE69737836T2 DE69737836T2 DE69737836T DE69737836T DE69737836T2 DE 69737836 T2 DE69737836 T2 DE 69737836T2 DE 69737836 T DE69737836 T DE 69737836T DE 69737836 T DE69737836 T DE 69737836T DE 69737836 T2 DE69737836 T2 DE 69737836T2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
- A61B2017/00154—Details of operation mode pulsed
- A61B2017/00172—Pulse trains, bursts, intermittent continuous operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Optics & Photonics (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Radiation-Therapy Devices (AREA)
- Electrotherapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Surgical Instruments (AREA)
- Laser Surgery Devices (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77841596A | 1996-12-31 | 1996-12-31 | |
| US778415 | 1996-12-31 | ||
| WOPCT/US97/11670 | 1997-07-03 | ||
| PCT/US1997/011670 WO1998000193A1 (en) | 1996-07-03 | 1997-07-03 | Multiple mechanical microporation of skin or mucosa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69737836D1 DE69737836D1 (de) | 2007-08-02 |
| DE69737836T2 true DE69737836T2 (de) | 2008-03-06 |
Family
ID=25113276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69737836T Expired - Lifetime DE69737836T2 (de) | 1996-12-31 | 1997-12-30 | Mikroporation von Gewebe zur Verabreichung von bioaktiven Substanzen |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1314400B1 (enExample) |
| JP (5) | JP2001512329A (enExample) |
| AT (1) | ATE365026T1 (enExample) |
| AU (1) | AU5623298A (enExample) |
| CA (2) | CA2789115C (enExample) |
| DE (1) | DE69737836T2 (enExample) |
| DK (1) | DK1314400T3 (enExample) |
| ES (1) | ES2289192T3 (enExample) |
| WO (1) | WO1998029134A2 (enExample) |
Families Citing this family (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3880697A (en) * | 1996-07-03 | 1998-01-21 | Altea Technologies, Inc. | Multiple mechanical microporation of skin or mucosa |
| US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6517532B1 (en) | 1997-05-15 | 2003-02-11 | Palomar Medical Technologies, Inc. | Light energy delivery head |
| US6527716B1 (en) | 1997-12-30 | 2003-03-04 | Altea Technologies, Inc. | Microporation of tissue for delivery of bioactive agents |
| US6173202B1 (en) | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
| JP2002517519A (ja) * | 1998-06-08 | 2002-06-18 | バレンティス・インコーポレーテッド | エレクトロポレーション用製剤 |
| PT1124607E (pt) | 1998-07-14 | 2008-12-31 | Altea Therapeutics Corp | Remoção controlada de membranas biológicas por carga pirotécnica, para transporte transmembranar |
| WO2000043058A1 (en) * | 1999-01-22 | 2000-07-27 | Powderject Research Limited | Method of enhancing needleless transdermal powdered drug delivery |
| EP1645305A1 (en) | 1999-06-08 | 2006-04-12 | Altea Therapeutics Corporation | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method for manufacturing |
| US6890553B1 (en) | 1999-07-08 | 2005-05-10 | Johnson & Johnson Consumer Companies, Inc. | Exothermic topical delivery device |
| AU6076200A (en) | 1999-07-08 | 2001-01-30 | Johnson & Johnson Consumer Companies, Inc. | Exothermic bandage |
| US20030078499A1 (en) | 1999-08-12 | 2003-04-24 | Eppstein Jonathan A. | Microporation of tissue for delivery of bioactive agents |
| US7133717B2 (en) | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
| US7113821B1 (en) | 1999-08-25 | 2006-09-26 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery |
| EP1222932B1 (en) * | 1999-10-14 | 2007-02-21 | Pola Chemical Industries Inc. | Compositions for electroporation |
| AU2001251349A1 (en) * | 2000-04-06 | 2001-10-23 | Sontra Medical, Inc. | Method and device for enhanced transdermal drug delivery |
| US7404815B2 (en) | 2000-05-01 | 2008-07-29 | Lifescan, Inc. | Tissue ablation by shear force for sampling biological fluids and delivering active agents |
| IL137689A0 (en) * | 2000-08-03 | 2001-10-31 | L R Res & Dev Ltd | System for enhanced chemical debridement |
| JP5507030B2 (ja) * | 2000-09-08 | 2014-05-28 | アルザ・コーポレーシヨン | 経路閉鎖を阻害することによる経皮的薬物流動の減少の抑制方法 |
| WO2002026191A2 (en) | 2000-09-28 | 2002-04-04 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue |
| US7632522B2 (en) | 2000-09-28 | 2009-12-15 | Nanocyte Inc. | Use of stinging cells/capsules for the delivery of active agents to keratinous substances |
| US6882884B1 (en) | 2000-10-13 | 2005-04-19 | Soundskin, L.L.C. | Process for the stimulation of production of extracellular dermal proteins in human tissue |
| US6794376B2 (en) * | 2000-12-06 | 2004-09-21 | William Beaumont Hospital | Methods and compositions for enhancing diffusion of therapeutic agents through tissue |
| WO2002064162A2 (en) | 2001-02-13 | 2002-08-22 | Government Of The United States, As Represented By The Secretary Of The Army | Vaccine for transcutaneous immunization |
| EP2316482A1 (en) | 2001-03-19 | 2011-05-04 | Intercell USA, Inc. | Transcutaneous immunostimulation |
| WO2003070905A2 (en) * | 2002-02-15 | 2003-08-28 | Zycos, Inc. | Electroporation methods for introducing bioactive agents into cells |
| AU2003265226A1 (en) | 2002-03-11 | 2003-12-19 | Altea Therapeutics Corporation | Transdermal drug delivery device, method and use |
| US9918665B2 (en) | 2002-03-11 | 2018-03-20 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
| EP1519755B1 (en) | 2002-03-26 | 2008-05-07 | Nanocyte Inc. | Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue |
| EP1499255B1 (en) | 2002-04-19 | 2015-07-22 | Syneron Medical Ltd. | Handheld transdermal drug delivery and analyte extraction |
| AU2003245573A1 (en) | 2002-06-19 | 2004-01-06 | Palomar Medical Technologies, Inc. | Method and apparatus for treatment of cutaneous and subcutaneous conditions |
| US8016811B2 (en) | 2003-10-24 | 2011-09-13 | Altea Therapeutics Corporation | Method for transdermal delivery of permeant substances |
| WO2006111201A1 (en) | 2005-04-18 | 2006-10-26 | Pantec Biosolutions Ag | Laser microporator |
| US8834862B2 (en) | 2005-04-19 | 2014-09-16 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent |
| US7856985B2 (en) | 2005-04-22 | 2010-12-28 | Cynosure, Inc. | Method of treatment body tissue using a non-uniform laser beam |
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-
1997
- 1997-12-30 EP EP03002035A patent/EP1314400B1/en not_active Expired - Lifetime
- 1997-12-30 DK DK03002035T patent/DK1314400T3/da active
- 1997-12-30 JP JP53029898A patent/JP2001512329A/ja not_active Withdrawn
- 1997-12-30 CA CA2789115A patent/CA2789115C/en not_active Expired - Lifetime
- 1997-12-30 CA CA2276312A patent/CA2276312C/en not_active Expired - Lifetime
- 1997-12-30 WO PCT/US1997/024127 patent/WO1998029134A2/en not_active Ceased
- 1997-12-30 DE DE69737836T patent/DE69737836T2/de not_active Expired - Lifetime
- 1997-12-30 AT AT03002035T patent/ATE365026T1/de active
- 1997-12-30 ES ES03002035T patent/ES2289192T3/es not_active Expired - Lifetime
- 1997-12-30 AU AU56232/98A patent/AU5623298A/en not_active Abandoned
- 1997-12-30 EP EP97952676A patent/EP0952850A2/en not_active Ceased
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2008
- 2008-06-16 JP JP2008157298A patent/JP2008307391A/ja not_active Withdrawn
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2009
- 2009-09-02 JP JP2009203124A patent/JP2010005425A/ja not_active Withdrawn
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2013
- 2013-01-31 JP JP2013016445A patent/JP5657040B2/ja not_active Expired - Fee Related
- 2013-03-08 JP JP2013046499A patent/JP5680685B2/ja not_active Expired - Lifetime
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| JP2013099586A (ja) | 2013-05-23 |
| DK1314400T3 (da) | 2007-10-15 |
| EP0952850A2 (en) | 1999-11-03 |
| JP2013165967A (ja) | 2013-08-29 |
| EP1314400A3 (en) | 2003-10-15 |
| WO1998029134A3 (en) | 1998-10-15 |
| CA2789115C (en) | 2014-04-29 |
| JP2001512329A (ja) | 2001-08-21 |
| CA2789115A1 (en) | 1998-07-09 |
| ATE365026T1 (de) | 2007-07-15 |
| CA2276312C (en) | 2012-11-27 |
| JP5657040B2 (ja) | 2015-01-21 |
| EP1314400A2 (en) | 2003-05-28 |
| WO1998029134A2 (en) | 1998-07-09 |
| AU5623298A (en) | 1998-07-31 |
| JP2008307391A (ja) | 2008-12-25 |
| JP2010005425A (ja) | 2010-01-14 |
| DE69737836D1 (de) | 2007-08-02 |
| ES2289192T3 (es) | 2008-02-01 |
| CA2276312A1 (en) | 1998-07-09 |
| EP1314400B1 (en) | 2007-06-20 |
| JP5680685B2 (ja) | 2015-03-04 |
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