DK1314400T3 - Mikroporering af væv til levering af bioaktive midler - Google Patents
Mikroporering af væv til levering af bioaktive midlerInfo
- Publication number
- DK1314400T3 DK1314400T3 DK03002035T DK03002035T DK1314400T3 DK 1314400 T3 DK1314400 T3 DK 1314400T3 DK 03002035 T DK03002035 T DK 03002035T DK 03002035 T DK03002035 T DK 03002035T DK 1314400 T3 DK1314400 T3 DK 1314400T3
- Authority
- DK
- Denmark
- Prior art keywords
- microporation
- permeant
- tissues
- delivery
- organism
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
- A61B2017/00154—Details of operation mode pulsed
- A61B2017/00172—Pulse trains, bursts, intermittent continuous operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77841596A | 1996-12-31 | 1996-12-31 | |
PCT/US1997/011670 WO1998000193A1 (en) | 1996-07-03 | 1997-07-03 | Multiple mechanical microporation of skin or mucosa |
PCT/US1997/024127 WO1998029134A2 (en) | 1996-12-31 | 1997-12-30 | Microporation of tissue for delivery of bioactive agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1314400T3 true DK1314400T3 (da) | 2007-10-15 |
Family
ID=25113276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03002035T DK1314400T3 (da) | 1996-12-31 | 1997-12-30 | Mikroporering af væv til levering af bioaktive midler |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0952850A2 (da) |
JP (5) | JP2001512329A (da) |
AT (1) | ATE365026T1 (da) |
AU (1) | AU5623298A (da) |
CA (2) | CA2789115C (da) |
DE (1) | DE69737836T2 (da) |
DK (1) | DK1314400T3 (da) |
ES (1) | ES2289192T3 (da) |
WO (1) | WO1998029134A2 (da) |
Families Citing this family (98)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6183434B1 (en) * | 1996-07-03 | 2001-02-06 | Spectrx, Inc. | Multiple mechanical microporation of skin or mucosa |
US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
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US6173202B1 (en) * | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
AU4219399A (en) * | 1998-06-08 | 1999-12-30 | Valentis, Inc. | Formulations for electroporation |
WO2000003758A1 (en) | 1998-07-14 | 2000-01-27 | Spectrx, Inc. | Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport |
IL144380A0 (en) * | 1999-01-22 | 2002-05-23 | Powderject Res Ltd | Method of enhancing needleless transdermal powdered drug delivery |
ES2260021T3 (es) | 1999-06-08 | 2006-11-01 | Altea Therapeutics Corporation | Aparatos para la microporacion de membranas biologicas utilizando dispositivos de interfaz de tejido de pelicula delgada, y su metodo. |
US6890553B1 (en) | 1999-07-08 | 2005-05-10 | Johnson & Johnson Consumer Companies, Inc. | Exothermic topical delivery device |
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US20030078499A1 (en) | 1999-08-12 | 2003-04-24 | Eppstein Jonathan A. | Microporation of tissue for delivery of bioactive agents |
US7113821B1 (en) * | 1999-08-25 | 2006-09-26 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery |
US7133717B2 (en) | 1999-08-25 | 2006-11-07 | Johnson & Johnson Consumer Companies, Inc. | Tissue electroperforation for enhanced drug delivery and diagnostic sampling |
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WO2003077970A2 (en) * | 2002-03-11 | 2003-09-25 | Altea Therapeutics Corporation | Transdermal integrated actuator device, methods of making and using same |
US9918665B2 (en) | 2002-03-11 | 2018-03-20 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
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WO2003089043A2 (en) | 2002-04-19 | 2003-10-30 | Transpharma Medical Ltd. | Handheld transdermal drug delivery and analyte extraction |
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EP1924196A2 (en) | 2005-09-15 | 2008-05-28 | Palomar Medical Technologies, Inc. | Skin optical characterization device |
JP4921795B2 (ja) | 2006-01-06 | 2012-04-25 | 株式会社東芝 | 超音波薬剤導入装置及び医用画像診断装置 |
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US20100004582A1 (en) * | 2006-10-25 | 2010-01-07 | Pantec Biosolutions Ag | Wide-Area Parasystemic Treatment of Skin Related Conditions |
WO2008091878A1 (en) | 2007-01-22 | 2008-07-31 | Altea Therapeutics Corporation | Transdermal porator and patch system and method for using same |
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CN102596116B (zh) | 2009-04-30 | 2015-01-14 | 斯尔替克美学股份有限公司 | 从皮下富脂细胞去除热量的装置、系统和方法 |
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KR101358374B1 (ko) | 2009-07-30 | 2014-02-05 | 알마 레이저 엘티디. | 초음파발생봉 |
US9014799B2 (en) * | 2009-10-08 | 2015-04-21 | Palo Alto Research Center Incorporated | Transmucosal drug delivery device and method including electrically-actuated permeation enhancement |
US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
US9844461B2 (en) | 2010-01-25 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants |
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US8676338B2 (en) | 2010-07-20 | 2014-03-18 | Zeltiq Aesthetics, Inc. | Combined modality treatment systems, methods and apparatus for body contouring applications |
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US10722395B2 (en) | 2011-01-25 | 2020-07-28 | Zeltiq Aesthetics, Inc. | Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells |
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US9844460B2 (en) | 2013-03-14 | 2017-12-19 | Zeltiq Aesthetics, Inc. | Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same |
US9545523B2 (en) | 2013-03-14 | 2017-01-17 | Zeltiq Aesthetics, Inc. | Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue |
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US11178823B2 (en) | 2014-04-07 | 2021-11-23 | Premier Citrus Apz, Llc | Systems and methods for using light energy to facilitate penetration of substances in plants |
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US10952891B1 (en) | 2014-05-13 | 2021-03-23 | Zeltiq Aesthetics, Inc. | Treatment systems with adjustable gap applicators and methods for cooling tissue |
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US10568759B2 (en) | 2014-08-19 | 2020-02-25 | Zeltiq Aesthetics, Inc. | Treatment systems, small volume applicators, and methods for treating submental tissue |
US9459201B2 (en) | 2014-09-29 | 2016-10-04 | Zyomed Corp. | Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing |
US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
US11154418B2 (en) | 2015-10-19 | 2021-10-26 | Zeltiq Aesthetics, Inc. | Vascular treatment systems, cooling devices, and methods for cooling vascular structures |
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WO2017120322A1 (en) | 2016-01-05 | 2017-07-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
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US10765552B2 (en) | 2016-02-18 | 2020-09-08 | Zeltiq Aesthetics, Inc. | Cooling cup applicators with contoured heads and liner assemblies |
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US11382790B2 (en) | 2016-05-10 | 2022-07-12 | Zeltiq Aesthetics, Inc. | Skin freezing systems for treating acne and skin conditions |
US10682297B2 (en) | 2016-05-10 | 2020-06-16 | Zeltiq Aesthetics, Inc. | Liposomes, emulsions, and methods for cryotherapy |
US10555831B2 (en) | 2016-05-10 | 2020-02-11 | Zeltiq Aesthetics, Inc. | Hydrogel substances and methods of cryotherapy |
KR101938187B1 (ko) * | 2017-01-03 | 2019-01-14 | (주)엠큐어 | 약물주입홀의 개폐가 가능한 니들모듈 |
KR101929761B1 (ko) * | 2017-01-03 | 2018-12-17 | (주)엠큐어 | 약물주입홀이 형성된 니들모듈 |
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CN110604867A (zh) * | 2018-06-15 | 2019-12-24 | 博健通大健康(深圳)有限公司 | 一种超声中频导药仪 |
CA3107932A1 (en) | 2018-07-31 | 2020-02-06 | Zeltiq Aesthetics, Inc. | Methods, devices, and systems for improving skin characteristics |
US11622943B2 (en) * | 2019-05-10 | 2023-04-11 | Chamkurkishtiah Panduranga Rao | System and method for allergen-specific epicutaneous immunotherapy |
CN112490602B (zh) * | 2020-10-19 | 2021-09-24 | 电子科技大学 | 一种基于多层结构的THz导波调控装置 |
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-
1997
- 1997-12-30 ES ES03002035T patent/ES2289192T3/es not_active Expired - Lifetime
- 1997-12-30 EP EP97952676A patent/EP0952850A2/en not_active Ceased
- 1997-12-30 JP JP53029898A patent/JP2001512329A/ja not_active Withdrawn
- 1997-12-30 WO PCT/US1997/024127 patent/WO1998029134A2/en not_active Application Discontinuation
- 1997-12-30 DK DK03002035T patent/DK1314400T3/da active
- 1997-12-30 CA CA2789115A patent/CA2789115C/en not_active Expired - Lifetime
- 1997-12-30 CA CA2276312A patent/CA2276312C/en not_active Expired - Lifetime
- 1997-12-30 AU AU56232/98A patent/AU5623298A/en not_active Abandoned
- 1997-12-30 EP EP03002035A patent/EP1314400B1/en not_active Expired - Lifetime
- 1997-12-30 DE DE69737836T patent/DE69737836T2/de not_active Expired - Lifetime
- 1997-12-30 AT AT03002035T patent/ATE365026T1/de active
-
2008
- 2008-06-16 JP JP2008157298A patent/JP2008307391A/ja not_active Withdrawn
-
2009
- 2009-09-02 JP JP2009203124A patent/JP2010005425A/ja not_active Withdrawn
-
2013
- 2013-01-31 JP JP2013016445A patent/JP5657040B2/ja not_active Expired - Fee Related
- 2013-03-08 JP JP2013046499A patent/JP5680685B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2789115A1 (en) | 1998-07-09 |
JP2001512329A (ja) | 2001-08-21 |
DE69737836D1 (de) | 2007-08-02 |
DE69737836T2 (de) | 2008-03-06 |
WO1998029134A2 (en) | 1998-07-09 |
EP1314400B1 (en) | 2007-06-20 |
JP5680685B2 (ja) | 2015-03-04 |
AU5623298A (en) | 1998-07-31 |
JP5657040B2 (ja) | 2015-01-21 |
ES2289192T3 (es) | 2008-02-01 |
CA2789115C (en) | 2014-04-29 |
JP2010005425A (ja) | 2010-01-14 |
EP0952850A2 (en) | 1999-11-03 |
EP1314400A2 (en) | 2003-05-28 |
JP2013165967A (ja) | 2013-08-29 |
JP2008307391A (ja) | 2008-12-25 |
CA2276312A1 (en) | 1998-07-09 |
WO1998029134A3 (en) | 1998-10-15 |
CA2276312C (en) | 2012-11-27 |
EP1314400A3 (en) | 2003-10-15 |
ATE365026T1 (de) | 2007-07-15 |
JP2013099586A (ja) | 2013-05-23 |
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