JP2001504331A5 - - Google Patents
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- Publication number
- JP2001504331A5 JP2001504331A5 JP1998521150A JP52115098A JP2001504331A5 JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5 JP 1998521150 A JP1998521150 A JP 1998521150A JP 52115098 A JP52115098 A JP 52115098A JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9623236.8 | 1996-11-07 | ||
| GBGB9623236.8A GB9623236D0 (en) | 1996-11-07 | 1996-11-07 | Notch |
| GB9715674.9 | 1997-07-24 | ||
| GBGB9715674.9A GB9715674D0 (en) | 1997-07-24 | 1997-07-24 | Notch |
| GB9719350.2 | 1997-09-11 | ||
| GBGB9719350.2A GB9719350D0 (en) | 1997-09-11 | 1997-09-11 | Notch |
| PCT/GB1997/003058 WO1998020142A1 (en) | 1996-11-07 | 1997-11-06 | Notch |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001504331A JP2001504331A (ja) | 2001-04-03 |
| JP2001504331A5 true JP2001504331A5 (https=) | 2005-05-12 |
| JP4339406B2 JP4339406B2 (ja) | 2009-10-07 |
Family
ID=27268574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52115098A Expired - Fee Related JP4339406B2 (ja) | 1996-11-07 | 1997-11-06 | 免疫療法に使用する医薬の製造におけるＳｅｒｒａｔｅまたはＤｅｌｔａの使用 |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP0942998B1 (https=) |
| JP (1) | JP4339406B2 (https=) |
| KR (1) | KR100393234B1 (https=) |
| CN (2) | CN1160371C (https=) |
| AT (1) | ATE299184T1 (https=) |
| AU (1) | AU736361B2 (https=) |
| BG (1) | BG103444A (https=) |
| CA (1) | CA2271248C (https=) |
| CZ (1) | CZ295997B6 (https=) |
| DE (1) | DE69733695T2 (https=) |
| ES (1) | ES2243986T3 (https=) |
| GB (2) | GB2335194B (https=) |
| GE (1) | GEP20043390B (https=) |
| IL (1) | IL129531A0 (https=) |
| NO (1) | NO992196L (https=) |
| NZ (1) | NZ335549A (https=) |
| PL (1) | PL333302A1 (https=) |
| RO (1) | RO120850B1 (https=) |
| TR (1) | TR199901000T2 (https=) |
| WO (1) | WO1998020142A1 (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0861261B9 (en) | 1995-06-28 | 2010-02-24 | Imperial Cancer Research Technology Limited | Nucleotide and protein sequences of vertebrate delta genes and methods based thereon |
| US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| GB9824045D0 (en) * | 1998-11-03 | 1998-12-30 | European Molecular Biology Lab Embl | Regulator protein |
| GB9827604D0 (en) * | 1998-12-15 | 1999-02-10 | Lorantis Ltd | Methods of immunosuppression |
| GB9927328D0 (en) | 1999-11-18 | 2000-01-12 | Lorantis Ltd | Immunotherapy |
| GB0019242D0 (en) * | 2000-08-04 | 2000-09-27 | Lorantis Ltd | Assay |
| US6689744B2 (en) | 2000-09-22 | 2004-02-10 | Genentech, Inc. | Notch receptor agonists and uses |
| JP4365583B2 (ja) * | 2000-09-22 | 2009-11-18 | ジェネンテック・インコーポレーテッド | ノッチレセプターアゴニスト及び用途 |
| RU2179862C1 (ru) * | 2000-12-26 | 2002-02-27 | Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" | Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки |
| GB0118155D0 (en) * | 2001-07-25 | 2001-09-19 | Lorantis Ltd | Superantigen |
| WO2003011317A1 (en) * | 2001-07-25 | 2003-02-13 | Lorantis Limited | Modulators of notch signalling for use in immunotherapy |
| GB0123379D0 (en) * | 2001-09-28 | 2001-11-21 | Lorantis Ltd | Modulators |
| DK1479767T3 (da) * | 2002-02-06 | 2013-11-25 | Sanbio Inc | Fremgangsmåde til differentiering/inducering af stromaceller fra knoglemarv til nerveceller ved overføring af Notch-gen |
| JP2006506322A (ja) * | 2002-04-05 | 2006-02-23 | ロランティス リミテッド | 内科療法 |
| WO2004013179A1 (en) * | 2002-08-03 | 2004-02-12 | Lorantis Limited | Conjugate of notch signalling pathway modulators and their use in medical treatment |
| GB0218879D0 (en) * | 2002-08-14 | 2002-09-25 | Lorantis Ltd | Medical treatment |
| GB0220658D0 (en) * | 2002-09-05 | 2002-10-16 | Lorantis Ltd | Immunotherapy |
| WO2004032969A1 (en) * | 2002-10-09 | 2004-04-22 | Lorantis Limited | Modulation of immune function |
| WO2004060262A2 (en) * | 2003-01-07 | 2004-07-22 | Lorantis Limited | Modulators of notch signalling for use in immunotherpapy |
| GB0300428D0 (en) * | 2003-01-09 | 2003-02-05 | Lorantis Ltd | Medical treatment |
| JP2006517533A (ja) * | 2003-01-23 | 2006-07-27 | ロランティス リミテッド | Ｎｏｔｃｈシグナル伝達経路のアクチベーターを用いる自己免疫疾患の治療 |
| GB0303663D0 (en) * | 2003-02-18 | 2003-03-19 | Lorantis Ltd | Assays and medical treatments |
| ATE474593T1 (de) * | 2003-03-21 | 2010-08-15 | Celldex Therapeutics Ltd | Behandlung von allergischen erkrankungen unter verwendung eines modulators des notch signaling pathway |
| WO2004083372A2 (en) * | 2003-03-21 | 2004-09-30 | Lorantis Limited | Modulators of the notch signaling pathway immobilized on particles for modifying immune responses |
| GB0307472D0 (en) * | 2003-04-01 | 2003-05-07 | Lorantis Ltd | Medical treatment |
| US7919092B2 (en) | 2006-06-13 | 2011-04-05 | Oncomed Pharmaceuticals, Inc. | Antibodies to notch receptors |
| EP2125887A4 (en) | 2007-01-24 | 2010-11-10 | Oncomed Pharm Inc | COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER |
| CN104402998A (zh) | 2008-07-08 | 2015-03-11 | 昂考梅德药品有限公司 | 分离的抗体 |
| JP2012500791A (ja) * | 2008-08-22 | 2012-01-12 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | Ｎｏｔｃｈ３シグナル伝達のデコイインヒビターとしてのヒトｎｏｔｃｈ３に基づく融合タンパク質 |
| US8709710B2 (en) | 2009-02-16 | 2014-04-29 | Deutsches Rheuma-Forschungszentrum Berlin | Methods of modulating interleukin-22 and immune response by notch regulators |
| WO2011025964A2 (en) | 2009-08-29 | 2011-03-03 | Abbott Laboratories | Therapeutic dll4 binding proteins |
| BR112012021941A2 (pt) | 2010-03-02 | 2022-02-01 | Abbvie Inc | Proteínas terapêuticas de ligação a dll4 |
| EP2694080B1 (en) * | 2011-04-06 | 2018-03-14 | SanBio, Inc. | Methods and compositions for modulating peripheral immune function |
| EP2780354A4 (en) * | 2011-11-16 | 2015-06-24 | Oncomed Pharm Inc | HUMAN NOTCH RECEPTOR MUTATIONS AND THEIR USE |
| US20150140043A1 (en) * | 2012-05-10 | 2015-05-21 | Institut National De La Sante De La Recherche Medical (Inserm) | Immunomodulatory methods using notch agonists |
| KR101573650B1 (ko) * | 2015-02-04 | 2015-12-01 | 성균관대학교산학협력단 | Hcmv 바이러스 복제 억제용 조성물 |
| BR112021003830A2 (pt) * | 2018-08-28 | 2021-07-20 | Fred Hutchinson Cancer Research Center | métodos e composições para terapia celular t adotiva incorporando sinalização notch induzida |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL101728A (en) * | 1991-05-03 | 2007-08-19 | Univ Yale | Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them |
| US5869282A (en) * | 1991-12-11 | 1999-02-09 | Imperial Cancer Research Technology, Ltd. | Nucleotide and protein sequences of the serrate gene and methods based thereon |
| US5786158A (en) * | 1992-04-30 | 1998-07-28 | Yale University | Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids |
| CA2182498A1 (en) * | 1994-02-01 | 1995-08-10 | William J. Larochelle | Fusion proteins that include antibody and nonantibody portions |
| US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| DE69635899T2 (de) * | 1995-11-17 | 2006-11-23 | Asahi Kasei Kabushiki Kaisha | Polypeptid, das die differenzierung unterdrueckt |
-
1997
- 1997-11-06 CZ CZ19991639A patent/CZ295997B6/cs not_active IP Right Cessation
- 1997-11-06 KR KR10-1999-7004079A patent/KR100393234B1/ko not_active Expired - Fee Related
- 1997-11-06 AU AU48765/97A patent/AU736361B2/en not_active Ceased
- 1997-11-06 WO PCT/GB1997/003058 patent/WO1998020142A1/en not_active Ceased
- 1997-11-06 GB GB9910276A patent/GB2335194B/en not_active Revoked
- 1997-11-06 CN CNB971811598A patent/CN1160371C/zh not_active Expired - Fee Related
- 1997-11-06 EP EP97911353A patent/EP0942998B1/en not_active Expired - Lifetime
- 1997-11-06 GE GE3531A patent/GEP20043390B/en unknown
- 1997-11-06 NZ NZ335549A patent/NZ335549A/en unknown
- 1997-11-06 AT AT97911353T patent/ATE299184T1/de not_active IP Right Cessation
- 1997-11-06 JP JP52115098A patent/JP4339406B2/ja not_active Expired - Fee Related
- 1997-11-06 IL IL12953197A patent/IL129531A0/xx unknown
- 1997-11-06 DE DE69733695T patent/DE69733695T2/de not_active Expired - Lifetime
- 1997-11-06 GB GB0023691A patent/GB2353094B/en not_active Expired - Fee Related
- 1997-11-06 PL PL97333302A patent/PL333302A1/xx unknown
- 1997-11-06 CA CA002271248A patent/CA2271248C/en not_active Expired - Fee Related
- 1997-11-06 ES ES97911353T patent/ES2243986T3/es not_active Expired - Lifetime
- 1997-11-06 TR TR1999/01000T patent/TR199901000T2/xx unknown
- 1997-11-06 RO RO99-00524A patent/RO120850B1/ro unknown
- 1997-11-06 EP EP05076507A patent/EP1616958A3/en not_active Withdrawn
- 1997-11-06 CN CNA2004100055918A patent/CN1524583A/zh active Pending
-
1999
- 1999-05-05 NO NO992196A patent/NO992196L/no unknown
- 1999-05-28 BG BG103444A patent/BG103444A/xx unknown