JP2001501936A5 - - Google Patents
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- Publication number
- JP2001501936A5 JP2001501936A5 JP1998516942A JP51694298A JP2001501936A5 JP 2001501936 A5 JP2001501936 A5 JP 2001501936A5 JP 1998516942 A JP1998516942 A JP 1998516942A JP 51694298 A JP51694298 A JP 51694298A JP 2001501936 A5 JP2001501936 A5 JP 2001501936A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2732096P | 1996-10-02 | 1996-10-02 | |
| US60/027,320 | 1996-10-02 | ||
| US4377697P | 1997-04-11 | 1997-04-11 | |
| US60/043,776 | 1997-04-11 | ||
| PCT/US1997/018001 WO1998014192A1 (en) | 1996-10-02 | 1997-10-01 | Vitronectin receptor antagonists |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235447A Division JP2010006838A (ja) | 1996-10-02 | 2009-10-09 | ビトロネクチンレセプター拮抗物質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001501936A JP2001501936A (ja) | 2001-02-13 |
| JP2001501936A5 true JP2001501936A5 (https=) | 2005-05-12 |
| JP4491072B2 JP4491072B2 (ja) | 2010-06-30 |
Family
ID=26702318
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51694298A Expired - Fee Related JP4491072B2 (ja) | 1996-10-02 | 1997-10-01 | ビトロネクチンレセプター拮抗物質 |
| JP2009235447A Pending JP2010006838A (ja) | 1996-10-02 | 2009-10-09 | ビトロネクチンレセプター拮抗物質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009235447A Pending JP2010006838A (ja) | 1996-10-02 | 2009-10-09 | ビトロネクチンレセプター拮抗物質 |
Country Status (36)
| Country | Link |
|---|---|
| EP (1) | EP0957917B1 (https=) |
| JP (2) | JP4491072B2 (https=) |
| KR (1) | KR100589578B1 (https=) |
| CN (1) | CN1114403C (https=) |
| AP (1) | AP1463A (https=) |
| AR (1) | AR008878A1 (https=) |
| AT (1) | ATE312089T1 (https=) |
| AU (1) | AU733417B2 (https=) |
| BG (1) | BG64581B1 (https=) |
| BR (1) | BR9712248B1 (https=) |
| CA (1) | CA2267224C (https=) |
| CO (1) | CO4900046A1 (https=) |
| CY (1) | CY2576B1 (https=) |
| CZ (1) | CZ299076B6 (https=) |
| DE (1) | DE69734833T2 (https=) |
| DK (1) | DK0957917T3 (https=) |
| DZ (1) | DZ2320A1 (https=) |
| EA (1) | EA002419B1 (https=) |
| ES (1) | ES2252775T3 (https=) |
| HU (1) | HU229221B1 (https=) |
| ID (1) | ID19623A (https=) |
| IL (1) | IL129243A (https=) |
| MA (1) | MA24361A1 (https=) |
| MY (1) | MY137606A (https=) |
| NO (1) | NO320194B1 (https=) |
| NZ (1) | NZ334953A (https=) |
| PE (1) | PE10499A1 (https=) |
| PL (1) | PL190859B1 (https=) |
| RO (1) | RO119881B1 (https=) |
| SA (1) | SA98180936B1 (https=) |
| SK (1) | SK285029B6 (https=) |
| TR (1) | TR199900737T2 (https=) |
| TW (1) | TW487702B (https=) |
| UA (1) | UA60311C2 (https=) |
| UY (2) | UY24735A1 (https=) |
| WO (1) | WO1998014192A1 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| TW527355B (en) | 1997-07-02 | 2003-04-11 | Bristol Myers Squibb Co | Inhibitors of farnesyl protein transferase |
| TR200000786T2 (tr) * | 1997-09-24 | 2000-08-21 | Smithkline Beecham Corporation | Vitronektin reseptör antagonisti |
| CN1273529A (zh) * | 1997-09-24 | 2000-11-15 | 史密丝克莱恩比彻姆公司 | 玻连蛋白受体拮抗剂 |
| US6372719B1 (en) | 1998-03-04 | 2002-04-16 | Jay Cunningham | ανβ3 integrin antagonists in combination with chemotherapeutic agents |
| DE19842415A1 (de) * | 1998-09-16 | 2000-03-23 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
| BR9916536A (pt) * | 1998-12-23 | 2002-01-02 | Searle & Co | Método para o tratamento ou prevenção de um distúrbio de neoplasia em um mamìfero em necessidade deste tratamento ou prevenção, e, combinação |
| CA2358855A1 (en) * | 1999-02-03 | 2000-08-10 | Merck & Co., Inc. | Benzazepine derivatives as alpha-v integrin receptor antagonists |
| EP2359831A3 (en) * | 1999-04-30 | 2012-02-01 | The Regents of the University of Michigan | Therapeutic applications of pro-apoptotic benzodiazepines |
| JP2003506452A (ja) * | 1999-08-06 | 2003-02-18 | スミスクライン・ビーチャム・コーポレイション | 発作の治療に有用なビトロネクチン受容体アンタゴニスト |
| US6514964B1 (en) | 1999-09-27 | 2003-02-04 | Amgen Inc. | Fused cycloheptane and fused azacycloheptane compounds and their methods of use |
| DE10027514A1 (de) * | 2000-06-06 | 2002-01-03 | Basf Ag | Liganden von Integrinrezeptoren |
| DE10028575A1 (de) | 2000-06-14 | 2002-03-14 | Basf Ag | Integrinliganden |
| FR2806082B1 (fr) * | 2000-03-07 | 2002-05-17 | Adir | Nouveaux composes bicycliques antagonistes des recepteurs de la vitronectine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| NZ539682A (en) | 2001-01-29 | 2006-03-31 | Dimensional Pharm Inc | Substituted indoles and their use as integrin antagonists |
| DE60230404D1 (https=) * | 2001-04-10 | 2009-01-29 | Smithkline Beecham Corp | |
| SE0101386D0 (sv) | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | New compounds |
| WO2002090325A2 (en) * | 2001-05-03 | 2002-11-14 | Merck & Co., Inc. | Benzazepinone alpha v integrin receptor antagonists |
| EP1443963B1 (en) | 2001-10-22 | 2014-05-21 | The Scripps Research Institute | Antibody targeting compounds |
| GB0215867D0 (en) * | 2002-07-09 | 2002-08-14 | Glaxosmithkline Spa | Novel method and compounds |
| WO2004089890A2 (en) * | 2003-04-04 | 2004-10-21 | Smithkline Beecham Corporation | Process and intermediates for preparing benzazepines |
| AU2012216372B2 (en) * | 2004-04-02 | 2015-01-22 | The Regents Of The University Of California | Methods and compositions for treating and preventing disease associated with alphaVbeta5 integrin |
| ES2671522T3 (es) | 2004-04-02 | 2018-06-06 | The Regents Of The University Of California | Métodos y composiciones para tratar y prevenir una enfermedad asociada con la integrina alfa V beta 5 |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| TW200635902A (en) * | 2004-12-21 | 2006-10-16 | Smithkline Beecham Corp | Methods and formulations |
| HRP20100559T1 (hr) * | 2005-11-29 | 2010-11-30 | Glaxosmithkline Llc | Liječenje neovaskularnih poremećaja oka, poput makularne degeneracije, angioidnih strija, uveitisa i edema makule |
| ES2457822T3 (es) | 2007-11-08 | 2014-04-29 | The General Hospital Corporation | Procedimientos y composiciones de tratamiento de enfermedades proteinúricas |
| AU2008321770B2 (en) * | 2007-11-16 | 2012-09-06 | Ube Industries, Ltd. | Benzazepinone compound |
| EP2257538B1 (en) * | 2008-03-06 | 2016-04-27 | GlaxoSmithKline LLC | Process for the preparation of benzodiazepine derivatives |
| EP2395992A2 (en) | 2009-02-10 | 2011-12-21 | The Scripps Research Institute | Chemically programmed vaccination |
| CN102427816A (zh) * | 2009-03-30 | 2012-04-25 | 宇部兴产株式会社 | 用于治疗或预防眼病的药物组合物 |
| JP5572996B2 (ja) * | 2009-05-15 | 2014-08-20 | 宇部興産株式会社 | ベンズアゼピノン化合物を有効成分として含有する医薬 |
| CA2767409C (en) | 2009-07-24 | 2018-10-30 | The Regents Of The University Of California | Methods and compositions for treating and preventing disease associated with .alpha.v.beta.5 integrin |
| WO2011062765A2 (en) | 2009-11-17 | 2011-05-26 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| EP2325194A1 (en) * | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
| SG11201609050UA (en) | 2014-05-30 | 2016-12-29 | Pfizer | Carbonitrile derivatives as selective androgen receptor modulators |
| CA3172692C (en) * | 2020-04-26 | 2024-05-14 | Jiangsu Nhwa Pharmaceutical Co., Ltd | 1,5-dihydro-2,4-benzodiazepine-3-one derivative and application thereof |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ314922A (en) * | 1992-12-21 | 1998-11-25 | Smithkline Beecham Corp | Benzodiazepinones; nitrogen containing heterocyclic intermediates and pharmaceutical compositions |
| EP0767792A4 (en) * | 1994-06-29 | 2002-11-20 | Smithkline Beecham Corp | VITRONECTIN RECEPTOR ANTAGONISTS |
| EP0762882A4 (en) * | 1994-06-29 | 2002-09-11 | Smithkline Beecham Corp | Vibronectin Receptor Antagonists |
| JPH10504825A (ja) * | 1994-08-22 | 1998-05-12 | スミスクライン・ビーチャム・コーポレイション | 二環式化合物 |
| WO1996026190A1 (en) * | 1995-02-22 | 1996-08-29 | Smithkline Beecham Corporation | Integrin receptor antagonists |
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
-
1997
- 1997-01-10 UA UA99031739A patent/UA60311C2/uk unknown
- 1997-09-29 DZ DZ970170A patent/DZ2320A1/xx active
- 1997-09-30 MA MA24817A patent/MA24361A1/fr unknown
- 1997-09-30 MY MYPI97004552A patent/MY137606A/en unknown
- 1997-10-01 DE DE69734833T patent/DE69734833T2/de not_active Expired - Lifetime
- 1997-10-01 PE PE1997000876A patent/PE10499A1/es not_active Application Discontinuation
- 1997-10-01 SK SK425-99A patent/SK285029B6/sk not_active IP Right Cessation
- 1997-10-01 CZ CZ0113299A patent/CZ299076B6/cs not_active IP Right Cessation
- 1997-10-01 EA EA199900356A patent/EA002419B1/ru not_active IP Right Cessation
- 1997-10-01 DK DK97909979T patent/DK0957917T3/da active
- 1997-10-01 TR TR1999/00737T patent/TR199900737T2/xx unknown
- 1997-10-01 BR BRPI9712248-3A patent/BR9712248B1/pt not_active IP Right Cessation
- 1997-10-01 NZ NZ334953A patent/NZ334953A/xx not_active IP Right Cessation
- 1997-10-01 JP JP51694298A patent/JP4491072B2/ja not_active Expired - Fee Related
- 1997-10-01 AP APAP/P/1999/001493A patent/AP1463A/en active
- 1997-10-01 WO PCT/US1997/018001 patent/WO1998014192A1/en not_active Ceased
- 1997-10-01 HU HU9903769A patent/HU229221B1/hu not_active IP Right Cessation
- 1997-10-01 PL PL332674A patent/PL190859B1/pl unknown
- 1997-10-01 ES ES97909979T patent/ES2252775T3/es not_active Expired - Lifetime
- 1997-10-01 CA CA002267224A patent/CA2267224C/en not_active Expired - Fee Related
- 1997-10-01 UY UY24735A patent/UY24735A1/es not_active IP Right Cessation
- 1997-10-01 ID IDP973335A patent/ID19623A/id unknown
- 1997-10-01 AU AU47462/97A patent/AU733417B2/en not_active Ceased
- 1997-10-01 RO RO99-00353A patent/RO119881B1/ro unknown
- 1997-10-01 CN CN97180168A patent/CN1114403C/zh not_active Expired - Fee Related
- 1997-10-01 EP EP97909979A patent/EP0957917B1/en not_active Expired - Lifetime
- 1997-10-01 CO CO97057225A patent/CO4900046A1/es unknown
- 1997-10-01 AT AT97909979T patent/ATE312089T1/de active
- 1997-10-01 KR KR1019997002811A patent/KR100589578B1/ko not_active Expired - Fee Related
- 1997-10-01 IL IL12924397A patent/IL129243A/en not_active IP Right Cessation
- 1997-10-02 AR ARP970104549A patent/AR008878A1/es active IP Right Grant
-
1998
- 1998-02-10 TW TW086114545A patent/TW487702B/zh not_active IP Right Cessation
- 1998-03-01 SA SA98180936A patent/SA98180936B1/ar unknown
- 1998-03-25 UY UY24935A patent/UY24935A1/es not_active IP Right Cessation
-
1999
- 1999-03-31 BG BG103299A patent/BG64581B1/bg unknown
- 1999-03-31 NO NO19991590A patent/NO320194B1/no not_active IP Right Cessation
-
2007
- 2007-05-18 CY CY0700010A patent/CY2576B1/xx unknown
-
2009
- 2009-10-09 JP JP2009235447A patent/JP2010006838A/ja active Pending