JP2000516223A5 - - Google Patents

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Publication number
JP2000516223A5
JP2000516223A5 JP1998509343A JP50934398A JP2000516223A5 JP 2000516223 A5 JP2000516223 A5 JP 2000516223A5 JP 1998509343 A JP1998509343 A JP 1998509343A JP 50934398 A JP50934398 A JP 50934398A JP 2000516223 A5 JP2000516223 A5 JP 2000516223A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998509343A
Other languages
English (en)
Japanese (ja)
Other versions
JP4405593B2 (ja
JP2000516223A (ja
Filing date
Publication date
Priority claimed from DE19632423A external-priority patent/DE19632423A1/de
Application filed filed Critical
Publication of JP2000516223A publication Critical patent/JP2000516223A/ja
Publication of JP2000516223A5 publication Critical patent/JP2000516223A5/ja
Application granted granted Critical
Publication of JP4405593B2 publication Critical patent/JP4405593B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP50934398A 1996-08-12 1997-07-30 チエノピリミジン類 Expired - Fee Related JP4405593B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19632423A DE19632423A1 (de) 1996-08-12 1996-08-12 Thienopyrimidine
DE19632423.8 1996-08-12
PCT/EP1997/004139 WO1998006722A1 (de) 1996-08-12 1997-07-30 Thienopyrimidine

Publications (3)

Publication Number Publication Date
JP2000516223A JP2000516223A (ja) 2000-12-05
JP2000516223A5 true JP2000516223A5 (Direct) 2005-05-12
JP4405593B2 JP4405593B2 (ja) 2010-01-27

Family

ID=7802392

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50934398A Expired - Fee Related JP4405593B2 (ja) 1996-08-12 1997-07-30 チエノピリミジン類

Country Status (28)

Country Link
US (1) US6110920A (Direct)
EP (1) EP0920431B1 (Direct)
JP (1) JP4405593B2 (Direct)
KR (1) KR100502271B1 (Direct)
CN (1) CN1081638C (Direct)
AR (1) AR009052A1 (Direct)
AT (1) ATE233265T1 (Direct)
AU (1) AU725227B2 (Direct)
BR (1) BR9711062A (Direct)
CA (1) CA2263561C (Direct)
CZ (1) CZ287772B6 (Direct)
DE (2) DE19632423A1 (Direct)
DK (1) DK0920431T3 (Direct)
ES (1) ES2191192T3 (Direct)
HU (1) HUP0001607A3 (Direct)
IL (1) IL128504A (Direct)
NO (1) NO990643D0 (Direct)
NZ (1) NZ334600A (Direct)
PL (1) PL190174B1 (Direct)
PT (1) PT920431E (Direct)
RU (1) RU2199541C2 (Direct)
SI (1) SI0920431T1 (Direct)
SK (1) SK282823B6 (Direct)
TR (1) TR199900308T2 (Direct)
TW (1) TW359672B (Direct)
UA (1) UA55421C2 (Direct)
WO (1) WO1998006722A1 (Direct)
ZA (1) ZA977156B (Direct)

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US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
US6974838B2 (en) 1998-08-24 2005-12-13 Sepracor Inc. Methods of treating or preventing pain using sibutramine metabolites
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US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
DE19950647A1 (de) * 1999-10-21 2001-04-26 Merck Patent Gmbh Imidazolderivate als Phosphodiesterase VII-Hemmer
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
CN1458933A (zh) * 2000-09-29 2003-11-26 日本曹达株式会社 噻吩并嘧啶化合物及其盐以及其制备方法
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US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
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US7375109B2 (en) * 2001-09-04 2008-05-20 N.V. Organon Glycine-substituted thieno[2,3-d]pyrimidines with combined LH and FSH agonistic activity
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US7208516B2 (en) 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7276529B2 (en) 2002-03-20 2007-10-02 Celgene Corporation Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
TW200410975A (en) * 2002-09-26 2004-07-01 Nihon Nohyaku Co Ltd New pesticide and method for using it, new substituted thienopyrimidine derivative, its intermediate, and method for producing it
GB0320300D0 (en) * 2003-08-29 2003-10-01 Cancer Rec Tech Ltd Pyrimidothiophene compounds
DE10351436A1 (de) * 2003-11-04 2005-06-09 Merck Patent Gmbh Verwendung von Thienopyrimidinen
GB0420719D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
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US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
AU2008297877C1 (en) * 2007-09-14 2013-11-07 Addex Pharma S.A. 1,3-disubstituted-4-phenyl-1 H-pyridin-2-ones
DE602008004794D1 (de) * 2007-09-14 2011-03-10 Addex Pharmaceuticals Sa 1',3'-disubstituierte 4-phenyl-3,4,5,6-tetrahydro-2h,1'h-ä1,4'übipyridinyl-2'-one
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US8785486B2 (en) * 2007-11-14 2014-07-22 Janssen Pharmaceuticals, Inc. Imidazo[1,2-A]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
US20100227853A1 (en) * 2008-04-18 2010-09-09 Trustees Of Boston College Inhibitors of cyclic amp phosphodiesterases
US8586733B2 (en) 2008-07-31 2013-11-19 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
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CN102186477B (zh) 2008-10-16 2013-07-17 奥梅-杨森制药有限公司 作为代谢型谷氨酸受体调节剂的吲哚和苯并吗啉衍生物
CN102232074B (zh) 2008-11-28 2014-12-03 奥梅-杨森制药有限公司 作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物
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EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
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JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
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SMT201900545T1 (it) 2014-01-21 2019-11-13 Janssen Pharmaceutica Nv Combinazioni comprendenti modulatori allosterici positivi o agonisti ortosterici del recettore glutammatergico metabotropico sottotipo 2 e loro utilizzo
JP6687550B2 (ja) 2014-06-23 2020-04-22 セルジーン コーポレイション 肝疾患又は肝機能異常を治療するためのアプレミラスト
AU2016378723B2 (en) 2015-12-22 2021-09-30 SHY Therapeutics LLC Compounds for the treatment of cancer and inflammatory disease
MX2019014875A (es) 2017-06-21 2021-01-29 SHY Therapeutics LLC Compuestos que interaccionan con la superfamilia ras para el tratamiento de cancer, enfermedades inflamatorias, rasopatias y enfermedad fibrotica.
MX2021001193A (es) 2018-08-07 2021-04-28 Firmenich Incorporated 2,2-dioxidos de 4-amino-1h-benzo[c][1,2,6]tiadiazina 5-sustituidos y formulaciones y usos de los mismos.
US12391705B2 (en) 2018-12-19 2025-08-19 Shy Therapeutics, Llc Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
CN116178374B (zh) * 2023-01-13 2024-10-08 河北医科大学 小电导钙激活钾离子通道激动剂及其合成和应用

Family Cites Families (5)

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GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
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