JP2000514801A5 - - Google Patents
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- Publication number
- JP2000514801A5 JP2000514801A5 JP1998505247A JP50524798A JP2000514801A5 JP 2000514801 A5 JP2000514801 A5 JP 2000514801A5 JP 1998505247 A JP1998505247 A JP 1998505247A JP 50524798 A JP50524798 A JP 50524798A JP 2000514801 A5 JP2000514801 A5 JP 2000514801A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2136696P | 1996-07-08 | 1996-07-08 | |
| US60/021,366 | 1996-07-08 | ||
| PCT/US1997/011320 WO1998001426A1 (en) | 1996-07-08 | 1997-07-01 | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000514801A JP2000514801A (ja) | 2000-11-07 |
| JP2000514801A5 true JP2000514801A5 (enExample) | 2005-03-10 |
| JP4202421B2 JP4202421B2 (ja) | 2008-12-24 |
Family
ID=21803790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50524798A Expired - Fee Related JP4202421B2 (ja) | 1996-07-08 | 1997-07-01 | 抗高血圧、心臓保護、抗乏血及び抗脂肪分解特性を有する化合物 |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0912520B1 (enExample) |
| JP (1) | JP4202421B2 (enExample) |
| KR (1) | KR20000023635A (enExample) |
| CN (1) | CN1228770A (enExample) |
| AP (1) | AP903A (enExample) |
| AT (1) | ATE239725T1 (enExample) |
| AU (1) | AU746590B2 (enExample) |
| BG (1) | BG103135A (enExample) |
| BR (1) | BR9710156A (enExample) |
| CA (1) | CA2259538C (enExample) |
| CZ (1) | CZ291785B6 (enExample) |
| DE (1) | DE69721776T2 (enExample) |
| EA (1) | EA001801B1 (enExample) |
| ES (1) | ES2199365T3 (enExample) |
| HU (1) | HUP9903815A3 (enExample) |
| IL (1) | IL127890A0 (enExample) |
| NO (1) | NO313671B1 (enExample) |
| OA (1) | OA10953A (enExample) |
| PL (1) | PL331036A1 (enExample) |
| SK (1) | SK2299A3 (enExample) |
| UA (1) | UA51716C2 (enExample) |
| WO (1) | WO1998001426A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376472B1 (en) * | 1996-07-08 | 2002-04-23 | Aventis Pharmaceuticals, Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
| GB9723590D0 (en) | 1997-11-08 | 1998-01-07 | Glaxo Group Ltd | Chemical compounds |
| YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
| GB9813554D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
| AU750462B2 (en) | 1998-06-23 | 2002-07-18 | Glaxo Group Limited | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| JP3598332B2 (ja) * | 1998-11-25 | 2004-12-08 | 株式会社第一ラジオアイソトープ研究所 | Ｎ−アシルオキシ環状アルキル化合物を有効成分とする医薬品および試薬 |
| JP2002534430A (ja) * | 1998-12-31 | 2002-10-15 | アベンティス・ファーマスーティカルズ・プロダクツ・インコーポレイテツド | Ｎ６−置換デアザアデノシン誘導体類の製造法 |
| GB0106867D0 (en) * | 2001-03-20 | 2001-05-09 | Glaxo Group Ltd | Process |
| CA2446605A1 (en) * | 2001-05-10 | 2002-11-21 | Aventis Pharma Deutschland Gmbh | Novel processes for the preparation of adenosine compounds and intermediates thereto |
| EP1258247A1 (en) * | 2001-05-14 | 2002-11-20 | Aventis Pharma Deutschland GmbH | Adenosine analogues for the treatment of insulin resistance syndrome and diabetes |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| HUP0200849A2 (hu) * | 2002-03-06 | 2004-08-30 | Sanofi-Synthelabo | N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra |
| EP1375508A1 (en) * | 2002-06-27 | 2004-01-02 | Aventis Pharma Deutschland GmbH | N6-substituted adenosine analogues and their use as pharmaceutical agents |
| US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| FR2862969A1 (fr) * | 2003-11-28 | 2005-06-03 | Oreal | Procede de preparation de derives paraphenylenediamine a groupement pyrrolidinyle, substitue par un radical azote, et composes intermediaires |
| EP1574508A1 (de) | 2004-01-30 | 2005-09-14 | Lonza AG | Verfahren zur Herstellung von Acetalen und Ketalen von 3-Amino-5-(hydroxymethyl)-cyclopentan-1,2-diolen, sowie deren Derivaten und Salzen |
| PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| JP2006022045A (ja) * | 2004-07-08 | 2006-01-26 | Kaneka Corp | 光学活性１−ｔ−ブトキシカルボニル−３−アミノピロリジン塩の単離精製方法 |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| US7671062B2 (en) | 2006-07-28 | 2010-03-02 | Bristol-Myers Squibb Company | Modulators of chemokine receptor activity, crystalline forms and process |
| US7629351B2 (en) | 2006-07-28 | 2009-12-08 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino) pyrrolidin-1-yl)cyclohexyl)acetamide and other modulators of chemokine receptor activity, crystalline forms and process |
| US7687508B2 (en) | 2006-07-28 | 2010-03-30 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| DE102007002260A1 (de) | 2007-01-16 | 2008-07-31 | Sanofi-Aventis | Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms |
| US8383812B2 (en) | 2009-10-13 | 2013-02-26 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes |
| KR102758609B1 (ko) * | 2016-01-14 | 2025-01-22 | 주식회사 한독 | A3 아데노신 수용체 길항 화합물, 그의 제조 방법 및 그의 의학적 용도 |
| CN110627765B (zh) * | 2019-10-14 | 2021-08-20 | 浙江乐普药业股份有限公司 | 一种替卡格雷关键中间体的制备方法 |
| CN112047919B (zh) * | 2020-09-16 | 2021-06-18 | 常州制药厂有限公司 | 一种替卡格雷中间体及其制备方法 |
| KR102308854B1 (ko) * | 2021-02-26 | 2021-10-05 | 퓨쳐메디신 주식회사 | 카보사이클릭 뉴클레오사이드 유도체를 포함하는 코로나바이러스감염증-19 예방 및 치료용 약학적 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
| WO1992005177A1 (en) * | 1990-09-25 | 1992-04-02 | Rhone-Poulenc Rorer International (Holdings) Inc. | Compounds having antihypertensive and anti-ischemic properties |
| WO1995018817A1 (fr) * | 1994-01-07 | 1995-07-13 | Laboratoires Upsa | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant |
| US5554746A (en) * | 1994-05-16 | 1996-09-10 | Isis Pharmaceuticals, Inc. | Lactam nucleic acids |
-
1997
- 1997-01-07 UA UA99020643A patent/UA51716C2/uk unknown
- 1997-07-01 CN CN97197444A patent/CN1228770A/zh active Pending
- 1997-07-01 AT AT97933212T patent/ATE239725T1/de not_active IP Right Cessation
- 1997-07-01 DE DE69721776T patent/DE69721776T2/de not_active Expired - Lifetime
- 1997-07-01 IL IL12789097A patent/IL127890A0/xx unknown
- 1997-07-01 WO PCT/US1997/011320 patent/WO1998001426A1/en not_active Ceased
- 1997-07-01 CA CA002259538A patent/CA2259538C/en not_active Expired - Fee Related
- 1997-07-01 AP APAP/P/1998/001426A patent/AP903A/en active
- 1997-07-01 AU AU36454/97A patent/AU746590B2/en not_active Ceased
- 1997-07-01 EP EP97933212A patent/EP0912520B1/en not_active Expired - Lifetime
- 1997-07-01 EA EA199900092A patent/EA001801B1/ru not_active IP Right Cessation
- 1997-07-01 HU HU9903815A patent/HUP9903815A3/hu unknown
- 1997-07-01 ES ES97933212T patent/ES2199365T3/es not_active Expired - Lifetime
- 1997-07-01 BR BR9710156A patent/BR9710156A/pt not_active IP Right Cessation
- 1997-07-01 CZ CZ199924A patent/CZ291785B6/cs not_active IP Right Cessation
- 1997-07-01 JP JP50524798A patent/JP4202421B2/ja not_active Expired - Fee Related
- 1997-07-01 SK SK22-99A patent/SK2299A3/sk unknown
- 1997-07-01 PL PL97331036A patent/PL331036A1/xx unknown
-
1999
- 1999-01-06 OA OA9900003A patent/OA10953A/en unknown
- 1999-01-07 NO NO19990063A patent/NO313671B1/no not_active IP Right Cessation
- 1999-01-08 KR KR1019997000085A patent/KR20000023635A/ko not_active Ceased
- 1999-02-01 BG BG103135A patent/BG103135A/bg unknown