JP2000514801A5 - - Google Patents
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- Publication number
- JP2000514801A5 JP2000514801A5 JP1998505247A JP50524798A JP2000514801A5 JP 2000514801 A5 JP2000514801 A5 JP 2000514801A5 JP 1998505247 A JP1998505247 A JP 1998505247A JP 50524798 A JP50524798 A JP 50524798A JP 2000514801 A5 JP2000514801 A5 JP 2000514801A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Description
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2136696P | 1996-07-08 | 1996-07-08 | |
| US60/021,366 | 1996-07-08 | ||
| PCT/US1997/011320 WO1998001426A1 (en) | 1996-07-08 | 1997-07-01 | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000514801A JP2000514801A (ja) | 2000-11-07 |
| JP2000514801A5 true JP2000514801A5 (ja) | 2005-03-10 |
| JP4202421B2 JP4202421B2 (ja) | 2008-12-24 |
Family
ID=21803790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50524798A Expired - Fee Related JP4202421B2 (ja) | 1996-07-08 | 1997-07-01 | 抗高血圧、心臓保護、抗乏血及び抗脂肪分解特性を有する化合物 |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0912520B1 (ja) |
| JP (1) | JP4202421B2 (ja) |
| KR (1) | KR20000023635A (ja) |
| CN (1) | CN1228770A (ja) |
| AP (1) | AP903A (ja) |
| AT (1) | ATE239725T1 (ja) |
| AU (1) | AU746590B2 (ja) |
| BG (1) | BG103135A (ja) |
| BR (1) | BR9710156A (ja) |
| CA (1) | CA2259538C (ja) |
| CZ (1) | CZ291785B6 (ja) |
| DE (1) | DE69721776T2 (ja) |
| EA (1) | EA001801B1 (ja) |
| ES (1) | ES2199365T3 (ja) |
| HU (1) | HUP9903815A3 (ja) |
| IL (1) | IL127890A0 (ja) |
| NO (1) | NO313671B1 (ja) |
| OA (1) | OA10953A (ja) |
| PL (1) | PL331036A1 (ja) |
| SK (1) | SK2299A3 (ja) |
| UA (1) | UA51716C2 (ja) |
| WO (1) | WO1998001426A1 (ja) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376472B1 (en) * | 1996-07-08 | 2002-04-23 | Aventis Pharmaceuticals, Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
| GB9723590D0 (en) | 1997-11-08 | 1998-01-07 | Glaxo Group Ltd | Chemical compounds |
| YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
| GB9813554D0 (en) | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
| KR20010071591A (ko) | 1998-06-23 | 2001-07-28 | 그레이엄 브레레톤, 레슬리 에드워즈 | 2-(퓨린-9-일)-테트라히드로푸란-3,4-디올 유도체 |
| WO2000030638A1 (fr) * | 1998-11-25 | 2000-06-02 | Daiichi Radioisotope Laboratories, Ltd. | Medicaments ou reactifs contenant des composes cycloalkyl n-acyloxyles |
| ATE275565T1 (de) | 1998-12-31 | 2004-09-15 | Aventis Pharma Inc | Verfahren zur herstellung von n6-substituierten deaza-adenosinderivaten |
| GB0106867D0 (en) * | 2001-03-20 | 2001-05-09 | Glaxo Group Ltd | Process |
| US20030069423A1 (en) * | 2001-05-10 | 2003-04-10 | Ayers Timothy A. | Novel processes for the preparation of adenosine compounds and intermediates thereto |
| EP1258247A1 (en) * | 2001-05-14 | 2002-11-20 | Aventis Pharma Deutschland GmbH | Adenosine analogues for the treatment of insulin resistance syndrome and diabetes |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| HUP0200849A2 (hu) * | 2002-03-06 | 2004-08-30 | Sanofi-Synthelabo | N-aminoacetil-2-ciano-pirrolidin-származékok, e vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra |
| EP1375508A1 (en) * | 2002-06-27 | 2004-01-02 | Aventis Pharma Deutschland GmbH | N6-substituted adenosine analogues and their use as pharmaceutical agents |
| US7163937B2 (en) | 2003-08-21 | 2007-01-16 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| FR2862969A1 (fr) * | 2003-11-28 | 2005-06-03 | Oreal | Procede de preparation de derives paraphenylenediamine a groupement pyrrolidinyle, substitue par un radical azote, et composes intermediaires |
| EP1574508A1 (de) | 2004-01-30 | 2005-09-14 | Lonza AG | Verfahren zur Herstellung von Acetalen und Ketalen von 3-Amino-5-(hydroxymethyl)-cyclopentan-1,2-diolen, sowie deren Derivaten und Salzen |
| PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
| JP2006022045A (ja) * | 2004-07-08 | 2006-01-26 | Kaneka Corp | 光学活性１−ｔ−ブトキシカルボニル−３−アミノピロリジン塩の単離精製方法 |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| US7629351B2 (en) | 2006-07-28 | 2009-12-08 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino) pyrrolidin-1-yl)cyclohexyl)acetamide and other modulators of chemokine receptor activity, crystalline forms and process |
| US7671062B2 (en) | 2006-07-28 | 2010-03-02 | Bristol-Myers Squibb Company | Modulators of chemokine receptor activity, crystalline forms and process |
| US7687508B2 (en) | 2006-07-28 | 2010-03-30 | Bristol-Myers Squibb Company | Cyclic derivatives as modulators of chemokine receptor activity |
| DE102007002260A1 (de) | 2007-01-16 | 2008-07-31 | Sanofi-Aventis | Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms |
| US8383812B2 (en) | 2009-10-13 | 2013-02-26 | Bristol-Myers Squibb Company | N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes |
| BR112018014525A2 (pt) * | 2016-01-14 | 2018-12-11 | Handok Inc | compostos que antagonizam receptor de adenosina a3, método para preparação dos mesmos e aplicação médica dos mesmos |
| CN110627765B (zh) * | 2019-10-14 | 2021-08-20 | 浙江乐普药业股份有限公司 | 一种替卡格雷关键中间体的制备方法 |
| CN112047919B (zh) * | 2020-09-16 | 2021-06-18 | 常州制药厂有限公司 | 一种替卡格雷中间体及其制备方法 |
| KR102308854B1 (ko) * | 2021-02-26 | 2021-10-05 | 퓨쳐메디신 주식회사 | 카보사이클릭 뉴클레오사이드 유도체를 포함하는 코로나바이러스감염증-19 예방 및 치료용 약학적 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2095960T3 (es) * | 1990-09-25 | 1997-03-01 | Rhone Poulenc Rorer Int | Compuestos que tienen propiedades antihipertensivas y antiisquemicas. |
| US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
| WO1995018817A1 (fr) * | 1994-01-07 | 1995-07-13 | Laboratoires Upsa | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant |
| US5554746A (en) * | 1994-05-16 | 1996-09-10 | Isis Pharmaceuticals, Inc. | Lactam nucleic acids |
-
1997
- 1997-01-07 UA UA99020643A patent/UA51716C2/uk unknown
- 1997-07-01 BR BR9710156A patent/BR9710156A/pt not_active IP Right Cessation
- 1997-07-01 CZ CZ199924A patent/CZ291785B6/cs not_active IP Right Cessation
- 1997-07-01 JP JP50524798A patent/JP4202421B2/ja not_active Expired - Fee Related
- 1997-07-01 PL PL97331036A patent/PL331036A1/xx unknown
- 1997-07-01 AU AU36454/97A patent/AU746590B2/en not_active Ceased
- 1997-07-01 DE DE69721776T patent/DE69721776T2/de not_active Expired - Lifetime
- 1997-07-01 CA CA002259538A patent/CA2259538C/en not_active Expired - Fee Related
- 1997-07-01 CN CN97197444A patent/CN1228770A/zh active Pending
- 1997-07-01 AT AT97933212T patent/ATE239725T1/de not_active IP Right Cessation
- 1997-07-01 HU HU9903815A patent/HUP9903815A3/hu unknown
- 1997-07-01 SK SK22-99A patent/SK2299A3/sk unknown
- 1997-07-01 WO PCT/US1997/011320 patent/WO1998001426A1/en not_active Application Discontinuation
- 1997-07-01 EA EA199900092A patent/EA001801B1/ru not_active IP Right Cessation
- 1997-07-01 AP APAP/P/1998/001426A patent/AP903A/en active
- 1997-07-01 ES ES97933212T patent/ES2199365T3/es not_active Expired - Lifetime
- 1997-07-01 EP EP97933212A patent/EP0912520B1/en not_active Expired - Lifetime
- 1997-07-01 IL IL12789097A patent/IL127890A0/xx unknown
-
1999
- 1999-01-06 OA OA9900003A patent/OA10953A/en unknown
- 1999-01-07 NO NO19990063A patent/NO313671B1/no not_active IP Right Cessation
- 1999-01-08 KR KR1019997000085A patent/KR20000023635A/ko not_active Application Discontinuation
- 1999-02-01 BG BG103135A patent/BG103135A/bg unknown