JP2000512631A5 - - Google Patents
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- Publication number
- JP2000512631A5 JP2000512631A5 JP1998500502A JP50050298A JP2000512631A5 JP 2000512631 A5 JP2000512631 A5 JP 2000512631A5 JP 1998500502 A JP1998500502 A JP 1998500502A JP 50050298 A JP50050298 A JP 50050298A JP 2000512631 A5 JP2000512631 A5 JP 2000512631A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9602263-7 | 1996-06-07 | ||
| SE9602263A SE9602263D0 (sv) | 1996-06-07 | 1996-06-07 | New amino acid derivatives |
| PCT/SE1997/000989 WO1997046577A1 (en) | 1996-06-07 | 1997-06-05 | New amino acid derivatives and their use as thrombin inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000512631A JP2000512631A (ja) | 2000-09-26 |
| JP2000512631A5 true JP2000512631A5 (enExample) | 2005-01-13 |
| JP4237824B2 JP4237824B2 (ja) | 2009-03-11 |
Family
ID=20402928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50050298A Expired - Fee Related JP4237824B2 (ja) | 1996-06-07 | 1997-06-05 | 新規なアミノ酸誘導体およびトロンビン阻害剤としてのその使用 |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US6255301B1 (enExample) |
| EP (1) | EP0910573B1 (enExample) |
| JP (1) | JP4237824B2 (enExample) |
| CN (1) | CN1129604C (enExample) |
| AR (1) | AR008046A1 (enExample) |
| AT (1) | ATE231883T1 (enExample) |
| AU (1) | AU723420B2 (enExample) |
| BR (1) | BR9709560A (enExample) |
| CA (1) | CA2255625A1 (enExample) |
| CZ (1) | CZ398698A3 (enExample) |
| DE (1) | DE69718791T2 (enExample) |
| DK (1) | DK0910573T3 (enExample) |
| EE (1) | EE9800425A (enExample) |
| ES (1) | ES2191840T3 (enExample) |
| HU (1) | HUP0002404A3 (enExample) |
| ID (1) | ID17016A (enExample) |
| IL (2) | IL127325A0 (enExample) |
| IS (1) | IS4906A (enExample) |
| NO (1) | NO317135B1 (enExample) |
| NZ (1) | NZ332964A (enExample) |
| PL (1) | PL330482A1 (enExample) |
| SE (1) | SE9602263D0 (enExample) |
| SK (1) | SK165398A3 (enExample) |
| TR (1) | TR199802536T2 (enExample) |
| WO (1) | WO1997046577A1 (enExample) |
| ZA (1) | ZA974542B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SA96170106A (ar) | 1995-07-06 | 2005-12-03 | أسترا أكتيبولاج | مشتقات حامض أميني جديدة |
| AR013084A1 (es) | 1997-06-19 | 2000-12-13 | Astrazeneca Ab | Derivados de amidino utiles como inhibidores de la trombina, composicion farmaceutica, utilizacion de dichos compuestos para la preparacion demedicamentos y proceso para la preparacion de los compuestos mencionados |
| SE9704543D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Ab | New compounds |
| AU750561B2 (en) | 1998-04-24 | 2002-07-25 | 3-Dimensional Pharmaceuticals, Inc. | Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines as protease inhibitors |
| SE9804313D0 (sv) | 1998-12-14 | 1998-12-14 | Astra Ab | New compounds |
| CA2355792A1 (en) | 1999-01-13 | 2000-07-20 | Astrazeneca Ab | New amidinobenzylamine derivatives and their use as thrombin inhibitors |
| AR023510A1 (es) | 1999-04-21 | 2002-09-04 | Astrazeneca Ab | Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina. |
| SE9902270D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
| SE0001803D0 (sv) * | 2000-05-16 | 2000-05-16 | Astrazeneca Ab | New compounds i |
| PT1311480E (pt) * | 2000-08-16 | 2008-11-11 | Astrazeneca Ab | Novos derivados amidino e sua utilização como inibidores da trombina |
| US6433186B1 (en) | 2000-08-16 | 2002-08-13 | Astrazeneca Ab | Amidino derivatives and their use as thormbin inhibitors |
| RU2300521C2 (ru) * | 2000-12-01 | 2007-06-10 | Астразенека Аб | Новые производные миндальной кислоты и их применение в качестве ингибиторов тромбина |
| AR035216A1 (es) | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
| US7129233B2 (en) | 2000-12-01 | 2006-10-31 | Astrazeneca Ab | Mandelic acid derivatives and their use as thrombin inhibitors |
| AR034517A1 (es) | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
| SE0201659D0 (sv) | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| SE0201661D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
| US7781424B2 (en) * | 2003-05-27 | 2010-08-24 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| TW200827336A (en) * | 2006-12-06 | 2008-07-01 | Astrazeneca Ab | New crystalline forms |
| US20090061000A1 (en) * | 2007-08-31 | 2009-03-05 | Astrazeneca Ab | Pharmaceutical formulation use 030 |
| EP2242759B1 (en) | 2008-02-06 | 2012-09-12 | AstraZeneca AB | Compounds |
| GB0913342D0 (en) | 2009-07-31 | 2009-09-16 | Astrazeneca Ab | Compounds - 801 |
| KR101181918B1 (ko) * | 2010-11-09 | 2012-09-11 | 주식회사 세라젬 | 온열치료기용 상하운동 조절장치 |
| EP3052498A1 (en) | 2013-09-30 | 2016-08-10 | Council of Scientific & Industrial Research | 3,7-diazabicyclo[3.3.1]nonane carboxamides as antithrombotic agents |
| ES2945905T3 (es) * | 2014-02-07 | 2023-07-10 | Exithera Pharmaceuticals Inc | Compuestos y composiciones terapéuticos |
| CN108530297B (zh) * | 2017-03-03 | 2021-09-24 | 联化科技股份有限公司 | 2-氯-3-甲基苯甲酸及其中间体的制备方法 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU178398B (en) | 1979-06-12 | 1982-04-28 | Gyogyszerkutato Intezet | Process for producing new agmatine derivatives of activity against haemagglutination |
| HU192646B (en) | 1984-12-21 | 1987-06-29 | Gyogyszerkutato Intezet | Process for preparing new n-alkyl-peptide aldehydes |
| AU600226B2 (en) | 1985-02-04 | 1990-08-09 | Merrell Pharmaceuticals Inc. | Novel peptidase inhibitors |
| US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| EP0362002B1 (en) | 1988-09-01 | 1995-07-26 | Merrell Dow Pharmaceuticals Inc. | HIV protease inhibitors |
| ZA897515B (en) | 1988-10-07 | 1990-06-27 | Merrell Dow Pharma | Novel peptidase inhibitors |
| TW201303B (enExample) | 1990-07-05 | 1993-03-01 | Hoffmann La Roche | |
| CA2075154A1 (en) | 1991-08-06 | 1993-02-07 | Neelakantan Balasubramanian | Peptide aldehydes as antithrombotic agents |
| SE9102462D0 (sv) | 1991-08-28 | 1991-08-28 | Astra Ab | New isosteric peptides |
| CZ333492A3 (en) | 1991-11-12 | 1993-09-15 | Lilly Co Eli | Dipeptide of l-azetidine-2-carboxylic acids and l-argininaldehyde, process of its preparation and pharmaceutical preparation in which said dipeptide is comprised |
| SE9103612D0 (sv) | 1991-12-04 | 1991-12-04 | Astra Ab | New peptide derivatives |
| DE69314478T2 (de) | 1992-03-04 | 1999-02-11 | Gyogyszerkutato Intezet Kft., Budapest | Neuartige antikoagulierende peptidderivate und arzneimittel die solche enthalten so wie entsprechendes herstellungsverfahren |
| TW223629B (enExample) | 1992-03-06 | 1994-05-11 | Hoffmann La Roche | |
| AU675981B2 (en) | 1992-12-02 | 1997-02-27 | Bristol-Myers Squibb Company | Guanidinyl-substituted heterocyclic thrombin inhibitors |
| US5583146A (en) | 1992-12-02 | 1996-12-10 | Bristol-Myers Squibb Company | Heterocyclic thrombin inhibitors |
| JPH06340619A (ja) | 1993-05-03 | 1994-12-13 | Bristol Myers Squibb Co | グアニジニルまたはアミジニル置換メチルアミノ複素環トロンビン抑制剤 |
| US5780631A (en) | 1993-06-03 | 1998-07-14 | Astra Aktiebolag | Starting materials in the synthesis of thrombin and kininogenase inhibitors |
| SE9301916D0 (sv) | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
| EP0648780A1 (en) | 1993-08-26 | 1995-04-19 | Bristol-Myers Squibb Company | Heterocyclic thrombin inhibitors |
| TW394760B (en) | 1993-09-07 | 2000-06-21 | Hoffmann La Roche | Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same |
| AU1025795A (en) | 1994-01-27 | 1995-08-03 | Mitsubishi Chemical Corporation | Prolineamide derivatives |
| US5707966A (en) | 1994-03-04 | 1998-01-13 | Eli Lilly And Company | Antithrombotic agents |
| US5705487A (en) | 1994-03-04 | 1998-01-06 | Eli Lilly And Company | Antithrombotic agents |
| US5726159A (en) | 1994-03-04 | 1998-03-10 | Eli Lilly And Company | Antithrombotic agents |
| IL112795A (en) | 1994-03-04 | 2001-01-28 | Astrazeneca Ab | Peptide derivatives as antithrombic agents their preparation and pharmaceutical compositions containing them |
| US5561146A (en) | 1994-06-10 | 1996-10-01 | Bristol-Myers Squibb Company | Modified guanidino and amidino thrombin inhibitors |
| DE4421052A1 (de) * | 1994-06-17 | 1995-12-21 | Basf Ag | Neue Thrombininhibitoren, ihre Herstellung und Verwendung |
| US5510369A (en) | 1994-07-22 | 1996-04-23 | Merck & Co., Inc. | Pyrrolidine thrombin inhibitors |
| DE4443390A1 (de) | 1994-12-06 | 1996-06-13 | Basf Ag | Neue dipeptidische p-Amidinobenzylamide mit N-terminalen Sulfonyl- bzw. Aminosulfonylresten |
| US5932567A (en) | 1995-02-10 | 1999-08-03 | Basf Aktiengesellschaft | Thrombin inhibitors |
| CA2211109A1 (en) * | 1995-02-17 | 1996-08-22 | Basf Aktiengesellschaft | Novel thrombin inhibitors |
| US5710130A (en) | 1995-02-27 | 1998-01-20 | Eli Lilly And Company | Antithrombotic agents |
| US5914319A (en) | 1995-02-27 | 1999-06-22 | Eli Lilly And Company | Antithrombotic agents |
| AU698911B2 (en) | 1995-04-04 | 1998-11-12 | Merck & Co., Inc. | Thrombin inhibitors |
| US5629324A (en) | 1995-04-10 | 1997-05-13 | Merck & Co., Inc. | Thrombin inhibitors |
| SA96170106A (ar) | 1995-07-06 | 2005-12-03 | أسترا أكتيبولاج | مشتقات حامض أميني جديدة |
| TWI238827B (en) | 1995-12-21 | 2005-09-01 | Astrazeneca Ab | Prodrugs of thrombin inhibitors |
| JPH1095898A (ja) | 1996-09-25 | 1998-04-14 | Sumitomo Bakelite Co Ltd | 難燃性樹脂組成物およびこれを用いた積層板 |
| DE19632773A1 (de) | 1996-08-14 | 1998-02-19 | Basf Ag | Neue Thrombininhibitoren |
| DE19632772A1 (de) | 1996-08-14 | 1998-02-19 | Basf Ag | Neue Benzamidine |
| SE9704543D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Ab | New compounds |
-
1996
- 1996-06-07 SE SE9602263A patent/SE9602263D0/xx unknown
-
1997
- 1997-05-23 ZA ZA9704542A patent/ZA974542B/xx unknown
- 1997-06-03 ID IDP971884A patent/ID17016A/id unknown
- 1997-06-05 US US08/860,871 patent/US6255301B1/en not_active Expired - Fee Related
- 1997-06-05 DK DK97926356T patent/DK0910573T3/da active
- 1997-06-05 DE DE69718791T patent/DE69718791T2/de not_active Expired - Fee Related
- 1997-06-05 AT AT97926356T patent/ATE231883T1/de not_active IP Right Cessation
- 1997-06-05 CN CN97196864A patent/CN1129604C/zh not_active Expired - Fee Related
- 1997-06-05 EP EP97926356A patent/EP0910573B1/en not_active Expired - Lifetime
- 1997-06-05 NZ NZ332964A patent/NZ332964A/xx not_active IP Right Cessation
- 1997-06-05 IL IL12732597A patent/IL127325A0/xx active IP Right Grant
- 1997-06-05 TR TR1998/02536T patent/TR199802536T2/xx unknown
- 1997-06-05 SK SK1653-98A patent/SK165398A3/sk unknown
- 1997-06-05 BR BR9709560A patent/BR9709560A/pt active Search and Examination
- 1997-06-05 JP JP50050298A patent/JP4237824B2/ja not_active Expired - Fee Related
- 1997-06-05 PL PL97330482A patent/PL330482A1/xx unknown
- 1997-06-05 CZ CZ983986A patent/CZ398698A3/cs unknown
- 1997-06-05 AU AU31140/97A patent/AU723420B2/en not_active Ceased
- 1997-06-05 CA CA002255625A patent/CA2255625A1/en not_active Abandoned
- 1997-06-05 EE EE9800425A patent/EE9800425A/xx unknown
- 1997-06-05 WO PCT/SE1997/000989 patent/WO1997046577A1/en not_active Ceased
- 1997-06-05 HU HU0002404A patent/HUP0002404A3/hu unknown
- 1997-06-05 ES ES97926356T patent/ES2191840T3/es not_active Expired - Lifetime
- 1997-06-06 AR ARP970102484A patent/AR008046A1/es not_active Application Discontinuation
-
1998
- 1998-11-25 IS IS4906A patent/IS4906A/is unknown
- 1998-11-30 IL IL127325A patent/IL127325A/en not_active IP Right Cessation
- 1998-12-04 NO NO19985700A patent/NO317135B1/no not_active IP Right Cessation
-
2001
- 2001-04-30 US US09/844,427 patent/US6838478B2/en not_active Expired - Fee Related