JP2000503012A5 - - Google Patents

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Publication number
JP2000503012A5
JP2000503012A5 JP1997524642A JP52464297A JP2000503012A5 JP 2000503012 A5 JP2000503012 A5 JP 2000503012A5 JP 1997524642 A JP1997524642 A JP 1997524642A JP 52464297 A JP52464297 A JP 52464297A JP 2000503012 A5 JP2000503012 A5 JP 2000503012A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997524642A
Other languages
English (en)
Japanese (ja)
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JP4358908B2 (ja
JP2000503012A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/000264 external-priority patent/WO1997024117A1/en
Publication of JP2000503012A publication Critical patent/JP2000503012A/ja
Publication of JP2000503012A5 publication Critical patent/JP2000503012A5/ja
Application granted granted Critical
Publication of JP4358908B2 publication Critical patent/JP4358908B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP52464297A 1996-01-02 1997-01-02 置換（アリール、ヘテロアリール、アリールメチル又はヘテロアリールメチル）ヒドロキサム酸化合物 Expired - Fee Related JP4358908B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US948496P 1996-01-02 1996-01-02
US60/009,484 1996-01-02
PCT/US1997/000264 WO1997024117A1 (en) 1996-01-02 1997-01-02 Substituted (aryl, heteroaryl, arylmethyl or heteroarylmethyl) hydroxamic acid compounds

Publications (3)

Publication Number Publication Date
JP2000503012A JP2000503012A (ja) 2000-03-14
JP2000503012A5 true JP2000503012A5 (enExample) 2004-11-11
JP4358908B2 JP4358908B2 (ja) 2009-11-04

Family

ID=21737943

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52464297A Expired - Fee Related JP4358908B2 (ja) 1996-01-02 1997-01-02 置換（アリール、ヘテロアリール、アリールメチル又はヘテロアリールメチル）ヒドロキサム酸化合物

Country Status (10)

Country Link
US (1) US6057369A (enExample)
EP (1) EP0871439B1 (enExample)
JP (1) JP4358908B2 (enExample)
AT (1) ATE262899T1 (enExample)
AU (1) AU1529897A (enExample)
DE (1) DE69728375T2 (enExample)
DK (1) DK0871439T3 (enExample)
ES (1) ES2217386T3 (enExample)
PT (1) PT871439E (enExample)
WO (1) WO1997024117A1 (enExample)

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US6288063B1 (en) 1998-05-27 2001-09-11 Bayer Corporation Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors
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US6172064B1 (en) * 1998-08-26 2001-01-09 Glaxo Wellcome Inc. Formamides as therapeutic agents
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US6358980B1 (en) * 1999-01-27 2002-03-19 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6800646B1 (en) 1999-02-08 2004-10-05 Pharmacia Corporation Sulfamato hydroxamic acid metalloprotease inhibitor
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US6869951B1 (en) 1999-07-16 2005-03-22 Pharmacia Corporation Method of changing conformation of a matrix metalloproteinase
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US6699899B1 (en) 1999-12-21 2004-03-02 Celgene Corporation Substituted acylhydroxamic acids and method of reducing TNFα levels
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JP2003533525A (ja) 2000-05-15 2003-11-11 ダーウィン・ディスカバリー・リミテッド Ｍｍｐおよびｔｎｆ阻害活性を有するヒドロキサム酸およびカルボン酸誘導体
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FR2809623B1 (fr) * 2000-06-05 2003-09-05 Sanjuan Benito Arranz Dans le traitement des maladies neurodegeneratives : (notamment alzheimer et parkinson), utilisation pour un medicament : du sildenafil (ou de ses derives)
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US6495719B2 (en) * 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7312247B2 (en) * 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
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US6683078B2 (en) 2001-07-19 2004-01-27 Pharmacia Corporation Use of sulfonyl aryl or heteroaryl hydroxamic acids and derivatives thereof as aggrecanase inhibitors
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BR0309671A (pt) 2002-04-25 2005-05-03 Pharmacia Corp ácidos de piperidinil- e piperazinil-sulfonilmetil hidroxâmicos e seu uso como inibidores de protease
TW200406197A (en) * 2002-04-25 2004-05-01 Ono Pharmaceutical Co Therapelitic agent for inflammatory bowel disease containing hydroxamic acid as effective component
WO2003099272A1 (en) * 2002-05-22 2003-12-04 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
JP2006502980A (ja) * 2002-06-25 2006-01-26 ファルマシア・コーポレーション アリールスルホニルヒドロキサム酸およびアミド誘導体、ならびにプロテアーゼ阻害薬としてのそれらの使用
WO2004046104A2 (en) * 2002-11-20 2004-06-03 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
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TW200418806A (en) 2003-01-13 2004-10-01 Fujisawa Pharmaceutical Co HDAC inhibitor
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US7524938B2 (en) 2003-04-04 2009-04-28 Yeda Research And Development Co., Ltd. Antibodies and pharmaceutical compositions containing same useful for inhibiting activity of metalloproteins
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WO2016128131A1 (en) * 2015-02-09 2016-08-18 National And Kapodistrian University Of Athens Beta-lactone inhibitors of phospholipase a2 and uses thereof
AU2019352741A1 (en) 2018-10-04 2021-05-06 Assistance Publique-Hôpitaux De Paris (Aphp) EGFR inhibitors for treating keratodermas

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