|
US5853719A
(en)
*
|
1996-04-30 |
1998-12-29 |
Duke University |
Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
|
|
US7585622B1
(en)
|
1996-10-01 |
2009-09-08 |
Geron Corporation |
Increasing the proliferative capacity of cells using telomerase reverse transcriptase
|
|
US6475789B1
(en)
*
|
1996-10-01 |
2002-11-05 |
University Technology Corporation |
Human telomerase catalytic subunit: diagnostic and therapeutic methods
|
|
IL129222A0
(en)
|
1996-10-01 |
2000-02-17 |
Geron Corp |
Telomerase reverse transcriptase
|
|
US6977073B1
(en)
|
1997-02-07 |
2005-12-20 |
Cem Cezayirli |
Method for stimulating an immune response
|
|
US6251665B1
(en)
|
1997-02-07 |
2001-06-26 |
Cem Cezayirli |
Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
|
|
US6228640B1
(en)
|
1997-02-07 |
2001-05-08 |
Cem Cezayirli |
Programmable antigen presenting cell of CD34 lineage
|
|
US20020041868A1
(en)
*
|
1997-04-15 |
2002-04-11 |
Charles Nicolette |
Cell fusions and methods of making and using the same
|
|
US20050169898A1
(en)
*
|
1997-04-15 |
2005-08-04 |
Jianlin Gong |
Cell fusions and methods of making and using the same
|
|
US7413864B2
(en)
*
|
1997-04-18 |
2008-08-19 |
Geron Corporation |
Treating cancer using a telomerase vaccine
|
|
US7622549B2
(en)
*
|
1997-04-18 |
2009-11-24 |
Geron Corporation |
Human telomerase reverse transcriptase polypeptides
|
|
US6977074B2
(en)
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6337200B1
(en)
*
|
1998-03-31 |
2002-01-08 |
Geron Corporation |
Human telomerase catalytic subunit variants
|
|
US7402307B2
(en)
*
|
1998-03-31 |
2008-07-22 |
Geron Corporation |
Method for identifying and killing cancer cells
|
|
EP1068296B1
(en)
|
1998-03-31 |
2011-08-10 |
Geron Corporation |
Compositions for eliciting an immune response to a telomerase antigen
|
|
US20030022854A1
(en)
*
|
1998-06-25 |
2003-01-30 |
Dow Steven W. |
Vaccines using nucleic acid-lipid complexes
|
|
US20040247662A1
(en)
*
|
1998-06-25 |
2004-12-09 |
Dow Steven W. |
Systemic immune activation method using nucleic acid-lipid complexes
|
|
FR2785542B1
(fr)
*
|
1998-11-06 |
2001-02-09 |
Pf Medicament |
UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE D'UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE QUI LUI EST ASSOCIEE VERS LES CELLULES PRESENTATRICES D'ANTIGENES TELLES QUE LES CELLULES DENDRITIQUES HUMAINES
|
|
US7713739B1
(en)
*
|
2000-11-17 |
2010-05-11 |
Novartis Vaccines And Diagnostics, Inc. |
Microparticle-based transfection and activation of dendritic cells
|
|
US7015204B1
(en)
|
1999-10-07 |
2006-03-21 |
Cornell Research Foundation, Inc. |
Protective immunity or immunological tolerance induced with RNA particularly total cellular RNA
|
|
US7541184B2
(en)
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
|
US6783939B2
(en)
*
|
2000-07-07 |
2004-08-31 |
Alphavax, Inc. |
Alphavirus vectors and virosomes with modified HIV genes for use in vaccines
|
|
US20020192681A1
(en)
*
|
2000-10-24 |
2002-12-19 |
Whitehead Institute For Biomedical Research |
Response of dendritic cells to a diverse set of pathogens
|
|
WO2002061389A2
(en)
*
|
2001-02-01 |
2002-08-08 |
Tanox, Inc. |
Methods to generate and identify monoclonal antibodies to a large number of human antigens
|
|
DE10112851C1
(de)
|
2001-03-16 |
2002-10-10 |
Gsf Forschungszentrum Umwelt |
Semi-allogene Antitumor-Vakzine mit HLA-haplo-identischen Antigen-präsentierenden Zellen
|
|
US20030082806A1
(en)
*
|
2001-04-27 |
2003-05-01 |
Xcyte Therapies, Inc. |
Maturation of antigen-presenting cells using activated T cells
|
|
GB0111015D0
(en)
*
|
2001-05-04 |
2001-06-27 |
Norsk Hydro As |
Genetic material
|
|
ES2340499T3
(es)
|
2001-06-05 |
2010-06-04 |
Curevac Gmbh |
Arnm de antigeno tumoral estabilizado con un contenido de g/c aumentado.
|
|
ES2330202T5
(es)
*
|
2001-09-06 |
2014-01-20 |
Alphavax, Inc. |
Sistemas vectores basados en replicones de alfavirus
|
|
EP1442125A4
(en)
*
|
2001-10-04 |
2004-12-08 |
Carlos Estuard Aguilar-Cordova |
CHIMERAL VIRUS VECTORS FOR GENE THERAPY
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
KR20050047518A
(ko)
*
|
2002-07-05 |
2005-05-20 |
듀크 유니버시티 |
혈관 면역요법
|
|
US20040161417A1
(en)
*
|
2002-08-14 |
2004-08-19 |
Eli Gilboa |
Method of enhancing CD4+ T cell responses
|
|
DE60327786D1
(de)
|
2002-09-12 |
2009-07-09 |
Oncotherapy Science Inc |
Kdr-peptide und diese enthaltende impfstoffe
|
|
AU2003296439B2
(en)
*
|
2002-12-10 |
2009-05-07 |
Argos Therapeutics, Inc. |
In situ maturation of dendritic cells
|
|
US7078218B2
(en)
*
|
2002-12-13 |
2006-07-18 |
Alphavax, Inc. |
Alphavirus particles and methods for preparation
|
|
US20040208848A1
(en)
*
|
2002-12-13 |
2004-10-21 |
Smith Jonathan F. |
Multi-antigenic alphavirus replicon particles and methods
|
|
US20060134067A1
(en)
*
|
2003-02-18 |
2006-06-22 |
Maxcyte, Inc. |
Loading of cells with antigens by electroporation
|
|
WO2004074451A2
(en)
*
|
2003-02-18 |
2004-09-02 |
Maxcyte, Inc. |
Loading of cells with antigens by electroporation
|
|
WO2004073641A2
(en)
|
2003-02-18 |
2004-09-02 |
Kevin Slawin |
Induced activation in dendritic cells
|
|
US7442381B2
(en)
*
|
2003-03-20 |
2008-10-28 |
Alphavax, Inc. |
Alphavirus replicons and helper constructs
|
|
DE602004021260D1
(de)
*
|
2003-07-11 |
2009-07-09 |
Alphavax Inc |
Cytomegalovirusimpfstoffe, die auf dem alphavirus basieren
|
|
DE10335833A1
(de)
*
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
|
CA2546378A1
(en)
*
|
2003-11-25 |
2005-06-09 |
Argos Therapeutics, Inc. |
Mrna transfected antigen presenting cells
|
|
US20050181035A1
(en)
*
|
2004-02-17 |
2005-08-18 |
Dow Steven W. |
Systemic immune activation method using non CpG nucleic acids
|
|
AU2005218638A1
(en)
*
|
2004-03-02 |
2005-09-15 |
Donald W. Kufe |
Methods and compositions for hybrid cell vaccines for the treatment and prevention of cancer
|
|
CN1989250B
(zh)
|
2004-05-18 |
2013-11-20 |
阿尔法瓦克斯公司 |
Tc-83衍生的甲病毒属载体、颗粒和方法
|
|
US20080293581A1
(en)
*
|
2004-05-24 |
2008-11-27 |
Rogler Charles E |
Rna Expression Microarrays
|
|
CA2504451A1
(en)
*
|
2004-08-10 |
2006-02-10 |
Geron Corporation |
Dendritic cell vaccines for treating cancer made from embryonic stem cells
|
|
ES2610781T3
(es)
|
2004-09-14 |
2017-05-03 |
Argos Therapeutics, Inc. |
Amplificación de patógenos independiente de la cepa y vacunas para estos
|
|
US20060216269A1
(en)
*
|
2004-09-17 |
2006-09-28 |
Kenichiro Hasumi |
Dendritic cell tumor injection (DCTI) therapy
|
|
US8076132B2
(en)
|
2004-09-17 |
2011-12-13 |
Hasumi International Research Foundation |
Dendritic cell tumor injection (DCTI) therapy
|
|
GB0501129D0
(en)
*
|
2005-01-19 |
2005-02-23 |
Ribostem Ltd |
Method of treatment by administration of RNA
|
|
ES2364670T3
(es)
|
2005-02-25 |
2011-09-12 |
Oncotherapy Science, Inc. |
Vacunas de péptidos para cánceres de pulmón que expresan polipéptidos ttk.
|
|
DK2095822T3
(da)
|
2005-02-28 |
2014-01-13 |
Oncotherapy Science Inc |
Epitoppeptider afledt af karendothelvækstfaktorreceptor-1 samt vacciner indeholdende disse peptider
|
|
JP5020935B2
(ja)
|
2005-04-08 |
2012-09-05 |
アルゴス セラピューティクス,インコーポレイティド |
樹状細胞組成物および方法
|
|
HUE027330T2
(en)
|
2005-07-27 |
2016-09-28 |
Oncotherapy Science Inc |
Colon cancer related gene tom34
|
|
EP1951281B1
(en)
|
2005-10-17 |
2015-04-15 |
Sloan Kettering Institute For Cancer Research |
Wt1 hla class ii-binding peptides and compositions and methods comprising same
|
|
WO2007120673A2
(en)
|
2006-04-10 |
2007-10-25 |
Sloan Kettering Institute For Cancer Research |
Immunogenic wt-1 peptides and methods of use thereof
|
|
EP2010659B1
(en)
|
2006-04-14 |
2014-06-18 |
CellScript, Inc. |
Kits and methods for generating 5' capped RNA
|
|
JP5570808B2
(ja)
|
2006-08-18 |
2014-08-13 |
アルゴス・セラピューティクス・インコーポレーテッド |
併用療法におけるcd83の使用
|
|
KR101543622B1
(ko)
|
2006-10-17 |
2015-08-11 |
온코세라피 사이언스 가부시키가이샤 |
Mphosph1 또는 depdc1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
|
|
CA3058450A1
(en)
*
|
2006-10-19 |
2008-04-24 |
Baylor College Of Medicine |
Generating an immune response by inducing cd40 and pattern recognition receptors
|
|
WO2008055354A1
(en)
*
|
2006-11-10 |
2008-05-15 |
Université de Montréal |
Rna-loaded dendritic cell compositions for eliciting cd4+ t cell help and related methods
|
|
TWI596109B
(zh)
|
2007-02-21 |
2017-08-21 |
腫瘤療法 科學股份有限公司 |
表現腫瘤相關抗原之癌症的胜肽疫苗
|
|
TW201425333A
(zh)
|
2007-04-11 |
2014-07-01 |
Oncotherapy Science Inc |
腫瘤血管內皮標誌8胜肽及包含此胜肽之疫苗
|
|
US8460913B2
(en)
|
2007-06-21 |
2013-06-11 |
Alpha Vax, Inc. |
Promoterless cassettes for expression of alpha virus structural proteins
|
|
US8569244B2
(en)
|
2007-08-20 |
2013-10-29 |
Oncotherapy Science, Inc. |
FOXM1 peptide and medicinal agent comprising the same
|
|
EP2254998B1
(en)
|
2008-02-28 |
2015-12-23 |
Argos Therapeutics, Inc. |
Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection
|
|
EP3156069B8
(en)
|
2008-06-20 |
2020-10-21 |
Duke University |
Compositions, methods, and kits for eliciting an immune response
|
|
CA2738031C
(en)
*
|
2008-09-22 |
2022-11-29 |
Baylor College Of Medicine |
Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
|
|
DK2352756T3
(da)
|
2008-11-24 |
2012-12-03 |
Helmholtz Zentrum Muenchen |
Højaffin T-cellereceptor og anvendelse af denne
|
|
TWI539160B
(zh)
|
2008-12-05 |
2016-06-21 |
腫瘤療法 科學股份有限公司 |
Wdrpuh抗原決定位胜肽以及含此胜肽之疫苗
|
|
US8728806B2
(en)
|
2008-12-06 |
2014-05-20 |
The Board Of Regents, The University Of Texas System |
Methods and compositions related to Th-1 dendritic cells
|
|
TWI469791B
(zh)
|
2009-02-18 |
2015-01-21 |
Oncotherapy Science Inc |
Foxm1胜肽以及含此胜肽之疫苗
|
|
US9841426B2
(en)
*
|
2009-03-11 |
2017-12-12 |
Marker Gene Technologies, Inc |
Intracellular organelle peptide targeted enzyme substrates
|
|
ES2617434T3
(es)
|
2009-03-18 |
2017-06-19 |
Oncotherapy Science, Inc. |
Péptidos NEIL3 y vacunas que incluyen los mismos
|
|
TWI507204B
(zh)
|
2009-05-26 |
2015-11-11 |
Oncotherapy Science Inc |
Cdc45l胜肽與含此胜肽之疫苗
|
|
TW201136604A
(en)
|
2009-12-14 |
2011-11-01 |
Oncotherapy Science Inc |
TMEM22 peptides and vaccines including the same
|
|
CN105601727B
(zh)
|
2010-03-11 |
2020-01-10 |
肿瘤疗法科学股份有限公司 |
Hjurp肽及包含它们的疫苗
|
|
TWI538685B
(zh)
|
2010-04-02 |
2016-06-21 |
腫瘤療法 科學股份有限公司 |
Ect2胜肽及含此胜肽之疫苗
|
|
US9089520B2
(en)
|
2010-05-21 |
2015-07-28 |
Baylor College Of Medicine |
Methods for inducing selective apoptosis
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP2625189B1
(en)
|
2010-10-01 |
2018-06-27 |
ModernaTX, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
AU2012236099A1
(en)
|
2011-03-31 |
2013-10-03 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
EP2557089A2
(en)
|
2011-07-15 |
2013-02-13 |
Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) |
Compositions and methods for immunomodulation
|
|
JP5564730B2
(ja)
|
2011-08-12 |
2014-08-06 |
オンコセラピー・サイエンス株式会社 |
Mphosph1ペプチドおよびそれを含むワクチン
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
DE19216461T1
(de)
|
2011-10-03 |
2021-10-07 |
Modernatx, Inc. |
Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
|
|
CN104066746B
(zh)
|
2011-10-28 |
2017-12-05 |
肿瘤疗法科学股份有限公司 |
Topk肽及包含它们的疫苗
|
|
CA3018046A1
(en)
|
2011-12-16 |
2013-06-20 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
AU2013207669C1
(en)
|
2012-01-13 |
2018-05-31 |
Memorial Sloan Kettering Cancer Center |
Immunogenic WT-1 peptides and methods of use thereof
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
WO2013151665A2
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins associated with human disease
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
JP6259983B2
(ja)
|
2012-07-10 |
2018-01-17 |
オンコセラピー・サイエンス株式会社 |
Th1細胞のKIF20Aエピトープペプチドおよびこれを含有するワクチン
|
|
PL2922554T3
(pl)
|
2012-11-26 |
2022-06-20 |
Modernatx, Inc. |
Na zmodyfikowany na końcach
|
|
US10815273B2
(en)
|
2013-01-15 |
2020-10-27 |
Memorial Sloan Kettering Cancer Center |
Immunogenic WT-1 peptides and methods of use thereof
|
|
RS61173B1
(sr)
|
2013-01-15 |
2021-01-29 |
Memorial Sloan Kettering Cancer Center |
Imunogeni wt-1 peptidi i postupci za njihovu upotrebu
|
|
US9434935B2
(en)
|
2013-03-10 |
2016-09-06 |
Bellicum Pharmaceuticals, Inc. |
Modified caspase polypeptides and uses thereof
|
|
TWI658049B
(zh)
|
2013-03-12 |
2019-05-01 |
腫瘤療法 科學股份有限公司 |
Kntc2胜肽及含此胜肽之疫苗
|
|
CA2905352A1
(en)
|
2013-03-14 |
2014-09-25 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlling t cell proliferation
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
ES2791598T3
(es)
|
2013-06-05 |
2020-11-05 |
Bellicum Pharmaceuticals Inc |
Métodos para inducir apoptosis parcial utilizando polipéptidos de caspasa
|
|
EP3049092A4
(en)
|
2013-09-24 |
2017-09-06 |
Duke University |
Compositions, methods and kits for eliciting an immune response
|
|
WO2015048744A2
(en)
|
2013-09-30 |
2015-04-02 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EP3052521A1
(en)
|
2013-10-03 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
|
WO2015062738A1
(en)
|
2013-11-01 |
2015-05-07 |
Curevac Gmbh |
Modified rna with decreased immunostimulatory properties
|
|
US10934346B2
(en)
|
2014-02-14 |
2021-03-02 |
Bellicum Pharmaceuticals, Inc. |
Modified T cell comprising a polynucleotide encoding an inducible stimulating molecule comprising MyD88, CD40 and FKBP12
|
|
US12214038B2
(en)
*
|
2014-07-22 |
2025-02-04 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for cancer immunotherapy
|
|
EP3981416B1
(en)
|
2014-08-04 |
2024-03-20 |
OncoTherapy Science, Inc. |
Koc1-derived peptide and vaccine including same
|
|
JP6700512B2
(ja)
|
2014-08-04 |
2020-05-27 |
オンコセラピー・サイエンス株式会社 |
Cdca1由来ペプチドおよびそれを含むワクチン
|
|
SG11201700838VA
(en)
|
2014-08-04 |
2017-03-30 |
Oncotherapy Science Inc |
Urlc10-derived peptide and vaccine containing same
|
|
AU2015312117A1
(en)
|
2014-09-02 |
2017-03-02 |
Bellicum Pharmaceuticals, Inc. |
Costimulation of chimeric antigen receptors by Myd88 and CD40 polypeptides
|
|
CA3017170C
(en)
*
|
2014-09-17 |
2021-03-23 |
The Johns Hopkins University |
Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells
|
|
HK1243631A1
(zh)
|
2014-10-27 |
2018-07-20 |
Fred Hutchinson Cancer Research Center |
用於提高过继细胞免疫疗法效力的组合物和方法
|
|
JP6718444B2
(ja)
|
2014-11-03 |
2020-07-08 |
アカデミッシュ ザイケンホイス レイデン (エイチ.オー.ディー.エヌ. エルユーエムシー) |
Bob1に対して指向されるT細胞レセプターおよびその使用
|
|
JP2018090491A
(ja)
*
|
2015-04-01 |
2018-06-14 |
株式会社細胞治療技術研究所 |
癌ワクチンの製造方法、及び癌ワクチン
|
|
US11090332B2
(en)
*
|
2015-05-21 |
2021-08-17 |
Regen BioPharma, Inc. |
Antigen specific mRNA cellular cancer vaccines
|
|
JP6666094B2
(ja)
*
|
2015-09-15 |
2020-03-13 |
株式会社東芝 |
吸着支持装置、および物品把持装置
|
|
BR112018005581A2
(pt)
|
2015-10-08 |
2018-10-16 |
Oncotherapy Science, Inc. |
peptídeo derivado de foxm1 e vacina incluindo o mesmo
|
|
US11780934B2
(en)
|
2016-02-05 |
2023-10-10 |
Institut Pasteur |
Use of inhibitors of ADAM12 as adjuvants in tumor therapies
|
|
EP3452082A1
(en)
|
2016-05-04 |
2019-03-13 |
Fred Hutchinson Cancer Research Center |
Cell-based neoantigen vaccines and uses thereof
|
|
US11331343B2
(en)
|
2016-06-29 |
2022-05-17 |
Duke University |
Compositions and methods for activating antigen presenting cells with chimeric poliovirus
|
|
WO2019135701A1
(en)
|
2018-01-05 |
2019-07-11 |
Nilsson Rolf Jonas Andreas |
Endogenous tumor-derived circular rna and proteins thereof for use as vaccine
|
|
TW202023581A
(zh)
|
2018-08-02 |
2020-07-01 |
日商腫瘤療法 科學股份有限公司 |
來自cdca1的胜肽及含有此的疫苗
|
|
US20250144143A1
(en)
*
|
2023-11-06 |
2025-05-08 |
Immunitybio, Inc. |
Virally Educated T cells
|