JP2000312590A5 - - Google Patents
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- Publication number
- JP2000312590A5 JP2000312590A5 JP1999276225A JP27622599A JP2000312590A5 JP 2000312590 A5 JP2000312590 A5 JP 2000312590A5 JP 1999276225 A JP1999276225 A JP 1999276225A JP 27622599 A JP27622599 A JP 27622599A JP 2000312590 A5 JP2000312590 A5 JP 2000312590A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- salt
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 description 33
- 150000003839 salts Chemical class 0.000 description 30
- 108090000623 proteins and genes Proteins 0.000 description 21
- 102000004169 proteins and genes Human genes 0.000 description 21
- 150000001408 amides Chemical class 0.000 description 11
- 150000002148 esters Chemical class 0.000 description 10
- 239000003446 ligand Substances 0.000 description 10
- 150000001413 amino acids Chemical class 0.000 description 8
- 108090000765 processed proteins & peptides Proteins 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 102000040430 polynucleotide Human genes 0.000 description 6
- 108091033319 polynucleotide Proteins 0.000 description 6
- 239000002157 polynucleotide Substances 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 4
- 238000012216 screening Methods 0.000 description 4
- 239000002773 nucleotide Substances 0.000 description 3
- 125000003729 nucleotide group Chemical group 0.000 description 3
- 125000000539 amino acid group Chemical group 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 239000000032 diagnostic agent Substances 0.000 description 1
- 229940039227 diagnostic agent Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
Priority Applications (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27622599A JP4486187B2 (ja) | 1998-10-27 | 1999-09-29 | 新規g蛋白質共役型レセプター蛋白質、そのdnaおよびそのリガンド |
| NZ510977A NZ510977A (en) | 1998-10-27 | 1999-10-26 | Novel G protein-coupled receptor proteins, DNAs thereof and ligands to the same |
| KR1020017005344A KR20010085974A (ko) | 1998-10-27 | 1999-10-26 | 신규 g 단백질 공액형 리셉터 단백질, 그 dna 및 그에대한 리간드 |
| BR9914835-8A BR9914835A (pt) | 1998-10-27 | 1999-10-26 | Proteìna e seus sais, método para fabricar a mesma, anticorpo para a mesma, ligando à mesma, método para determinar o mesmo, peptìdeo parcial da proteìna ou seus ésteres ou suas amidas ou seus sais, polinucleotìdeo, vetor recombinante, transformante, composição de diagnóstico, composição farmacêutica, composto ou seus sais, método para triar o mesmo, kit para triar o mesmo, método para quantificar a proteìna, peptìdeo, uma amida deste, um éster deste ou um sal deste, amida ou sal do peptìdeo, método para triagem, e, kit para filtragem |
| PL99347553A PL347553A1 (en) | 1998-10-27 | 1999-10-26 | Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same |
| IL14242899A IL142428A0 (en) | 1998-10-27 | 1999-10-26 | Novel g protein-couple receptor proteins, dna's thereof and ligands to the same |
| CN99812722A CN1324405A (zh) | 1998-10-27 | 1999-10-26 | 新型g蛋白偶联型受体蛋白、dna及其配体 |
| SK550-2001A SK5502001A3 (en) | 1998-10-27 | 1999-10-26 | Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same |
| AU62306/99A AU6230699A (en) | 1998-10-27 | 1999-10-26 | Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same |
| CA002347294A CA2347294A1 (en) | 1998-10-27 | 1999-10-26 | Novel g protein coupled receptor protein, dna and its ligand |
| HU0104937A HUP0104937A2 (hu) | 1998-10-27 | 1999-10-26 | Új, G-fehérjéhez kapcsolt receptorfehérje, DNS-e és ligandja |
| CZ20011358A CZ20011358A3 (cs) | 1998-10-27 | 1999-10-26 | Nový receptorový protein spojený s G proteinem, DNA a její ligand |
| PCT/JP1999/005905 WO2000024890A1 (en) | 1998-10-27 | 1999-10-26 | Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same |
| US09/830,428 US6699965B1 (en) | 1998-10-27 | 1999-10-26 | Peptides that activate the G-protein coupled receptor protein, 0T7T175 |
| DE69938666T DE69938666D1 (de) | 1998-10-27 | 1999-10-26 | Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für diese |
| EP99949421A EP1126028B1 (en) | 1998-10-27 | 1999-10-26 | Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same |
| AT99949421T ATE394485T1 (de) | 1998-10-27 | 1999-10-26 | Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für diese |
| IDW20010936A ID28288A (id) | 1998-10-27 | 1999-10-27 | Protein reseptor yang tergandeng protein g baru, dna dan ligannya |
| NO20012059A NO20012059L (no) | 1998-10-27 | 2001-04-26 | Nye G-protein-koplede reseptorproteiner, DNA derav og ligander til det samme |
| US10/771,417 US7314754B2 (en) | 1998-10-27 | 2004-02-05 | Polynucleotide encoding the hOT7T175 G protein coupled receptor |
| US11/976,414 US7608409B2 (en) | 1998-10-27 | 2007-10-24 | Screening assay using G-protein coupled receptor protein OT7T175 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30594998 | 1998-10-27 | ||
| JP2771099 | 1999-02-04 | ||
| JP11-27710 | 1999-03-04 | ||
| JP5720799 | 1999-03-04 | ||
| JP10-305949 | 1999-03-04 | ||
| JP11-57207 | 1999-03-04 | ||
| JP27622599A JP4486187B2 (ja) | 1998-10-27 | 1999-09-29 | 新規g蛋白質共役型レセプター蛋白質、そのdnaおよびそのリガンド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000312590A JP2000312590A (ja) | 2000-11-14 |
| JP2000312590A5 true JP2000312590A5 (enExample) | 2006-11-02 |
| JP4486187B2 JP4486187B2 (ja) | 2010-06-23 |
Family
ID=27458743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP27622599A Expired - Fee Related JP4486187B2 (ja) | 1998-10-27 | 1999-09-29 | 新規g蛋白質共役型レセプター蛋白質、そのdnaおよびそのリガンド |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US6699965B1 (enExample) |
| EP (1) | EP1126028B1 (enExample) |
| JP (1) | JP4486187B2 (enExample) |
| KR (1) | KR20010085974A (enExample) |
| CN (1) | CN1324405A (enExample) |
| AT (1) | ATE394485T1 (enExample) |
| AU (1) | AU6230699A (enExample) |
| BR (1) | BR9914835A (enExample) |
| CA (1) | CA2347294A1 (enExample) |
| CZ (1) | CZ20011358A3 (enExample) |
| DE (1) | DE69938666D1 (enExample) |
| HU (1) | HUP0104937A2 (enExample) |
| ID (1) | ID28288A (enExample) |
| IL (1) | IL142428A0 (enExample) |
| NO (1) | NO20012059L (enExample) |
| NZ (1) | NZ510977A (enExample) |
| PL (1) | PL347553A1 (enExample) |
| SK (1) | SK5502001A3 (enExample) |
| WO (1) | WO2000024890A1 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002536989A (ja) * | 1999-02-24 | 2002-11-05 | メルク エンド カムパニー インコーポレーテッド | ガラニン受容体と類似したgタンパク質共役受容体 |
| EP1273658A4 (en) * | 2000-03-30 | 2004-08-11 | Takeda Chemical Industries Ltd | NEW PROTEIN, THEIR DNA AND METHOD FOR THE PRODUCTION THEREOF |
| EP1168259A3 (en) | 2000-06-28 | 2003-12-17 | Hitachi, Ltd. | Data management method and system for IC card |
| AU8020201A (en) * | 2000-08-30 | 2002-03-13 | Wakenyaku Co Ltd | Design and construction of transcription template for synthesizing cell-free protein, and dilution batch-type method of synthesizing cell-free wheat germ protein by using the same |
| JP2002109169A (ja) | 2000-09-29 | 2002-04-12 | Hitachi Ltd | 作業支援方法並びにシステム及び作業支援方法を記録した記録媒体 |
| ATE416784T1 (de) | 2000-12-01 | 2008-12-15 | Takeda Pharmaceutical | Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz |
| WO2002059344A2 (en) * | 2000-12-18 | 2002-08-01 | Merck & Co., Inc. | Gpr54 g protein-coupled receptor |
| WO2002057309A1 (fr) * | 2001-01-18 | 2002-07-25 | Takeda Chemical Industries, Ltd. | Nouvelle proteine receptrice couplee a la proteine g et adn de cette proteine |
| WO2002072816A1 (fr) * | 2001-02-26 | 2002-09-19 | Takeda Chemical Industries, Ltd. | Proteine de recepteur murin de type kiss-1 et adn correspondant |
| WO2002083735A1 (fr) * | 2001-04-06 | 2002-10-24 | Takeda Chemical Industries, Ltd. | Nouvelle proteine receptrice et son adn |
| AU2008201995A1 (en) * | 2001-09-18 | 2008-05-29 | Genentech, Inc. | Compositions and methods for the diagnosis and treament of tumor |
| KR101008758B1 (ko) | 2001-09-18 | 2011-01-14 | 제넨테크, 인크. | 종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물 |
| CA2460803A1 (en) | 2001-09-19 | 2003-04-03 | Takeda Chemical Industries, Ltd. | Antibody against metastin and use thereof in diagnosing pregnancy |
| AU2003201854A1 (en) * | 2002-01-11 | 2003-07-30 | Takeda Chemical Industries, Ltd. | PROCESS FOR PRODUCING KiSS-1 PEPTIDE |
| JP2006521082A (ja) * | 2002-09-11 | 2006-09-21 | ジェネンテック・インコーポレーテッド | 免疫関連疾患の治療のための新規組成物と方法 |
| US20060241051A1 (en) | 2002-12-26 | 2006-10-26 | Chieko Kitada | Metastin derivatives and use thereof |
| US6800611B2 (en) * | 2003-01-06 | 2004-10-05 | Takeda Chemical Industries, Ltd. | Metastin derivatives and their use |
| CA2518541C (en) * | 2003-03-12 | 2013-05-21 | Takeda Pharmaceutical Company Limited | Gonadal function improving agents |
| JP4639052B2 (ja) * | 2003-03-12 | 2011-02-23 | 武田薬品工業株式会社 | 性腺機能改善剤 |
| EP1464652A1 (en) * | 2003-04-02 | 2004-10-06 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases |
| AU2004234399A1 (en) * | 2003-04-28 | 2004-11-11 | Wyeth | Methods utilising G-protein coupled receptor 54 |
| WO2004101747A2 (en) * | 2003-05-07 | 2004-11-25 | The General Hospital Corporation | Identification and use of gpr54 and its ligands for reproductive disorders and contraception |
| WO2005040833A1 (en) * | 2003-10-21 | 2005-05-06 | Bayer Healthcare Ag | Regulation of human metastin recognising receptors |
| JP4346650B2 (ja) | 2004-06-25 | 2009-10-21 | 武田薬品工業株式会社 | メタスチン誘導体およびその用途 |
| AR058584A1 (es) | 2005-12-22 | 2008-02-13 | Takeda Pharmaceutical | Derivados de metastina y uso de los mismos |
| US8404643B2 (en) | 2005-12-22 | 2013-03-26 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| US20090099334A1 (en) * | 2005-12-22 | 2009-04-16 | Takeda Pharmaceutical Company Limited | Metastin derivatives and use thereof |
| ITMI20061607A1 (it) | 2006-08-09 | 2008-02-10 | Maria Vincenza Carriero | Peptidi con attivita farmacologica |
| JO3048B1 (ar) | 2006-10-25 | 2016-09-05 | Takeda Pharmaceuticals Co | مشتقات متاستين واستخدامها |
| JPWO2009131191A1 (ja) * | 2008-04-24 | 2011-08-25 | 武田薬品工業株式会社 | メタスチン誘導体およびその用途 |
| WO2010013762A1 (ja) | 2008-07-30 | 2010-02-04 | 武田薬品工業株式会社 | メタスチン誘導体およびその用途 |
| MX2011003117A (es) * | 2008-09-19 | 2011-04-21 | Nektar Therapeutics | Conjugados polimericos de peptidos terapeuticos. |
| EP2340047A1 (en) * | 2008-09-19 | 2011-07-06 | Nektar Therapeutics | Polymer conjugates of kiss1 peptides |
| WO2010137022A1 (en) | 2009-05-27 | 2010-12-02 | Yeda Research And Development Co. Ltd | Gpr54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities |
| EP2873422A4 (en) | 2012-07-10 | 2015-12-30 | Takeda Pharmaceutical | PHARMACEUTICAL PREPARATION FOR INJECTION |
| CN109206481B (zh) | 2017-07-05 | 2023-08-18 | 尚华医药科技(江西)有限公司 | 一种肽类化合物、其应用及含其的组合物 |
| CN109212217B (zh) * | 2018-11-07 | 2021-09-10 | 李玉民 | 基于amy1a蛋白胃癌检测试剂盒及其使用方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5436155A (en) * | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
| EP0804575A1 (en) | 1994-08-11 | 1997-11-05 | Takeda Chemical Industries, Ltd. | G protein coupled receptor protein, production, and use thereof |
| WO1997013778A1 (en) | 1995-10-11 | 1997-04-17 | The Penn State Research Foundation | A metastasis suppressor gene |
| US6010877A (en) * | 1997-01-10 | 2000-01-04 | Smithkline Beecham Corporation | cDNA clone HE8CS41 that encodes a novel 7-transmembrane receptor |
| US5851798A (en) * | 1997-01-27 | 1998-12-22 | Smithkline Beecham Corporation | Nucleic acid encoding human GPR14 receptor |
| US6420526B1 (en) * | 1997-03-07 | 2002-07-16 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| CA2283299A1 (en) | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 186 human secreted proteins |
| JP2002536989A (ja) * | 1999-02-24 | 2002-11-05 | メルク エンド カムパニー インコーポレーテッド | ガラニン受容体と類似したgタンパク質共役受容体 |
| US20020077469A1 (en) * | 1999-03-10 | 2002-06-20 | Borowsky Beth E. | DNA encoding orphan SNORF11 receptor |
| CA2518541C (en) * | 2003-03-12 | 2013-05-21 | Takeda Pharmaceutical Company Limited | Gonadal function improving agents |
-
1999
- 1999-09-29 JP JP27622599A patent/JP4486187B2/ja not_active Expired - Fee Related
- 1999-10-26 EP EP99949421A patent/EP1126028B1/en not_active Expired - Lifetime
- 1999-10-26 US US09/830,428 patent/US6699965B1/en not_active Expired - Fee Related
- 1999-10-26 NZ NZ510977A patent/NZ510977A/xx unknown
- 1999-10-26 IL IL14242899A patent/IL142428A0/xx unknown
- 1999-10-26 CZ CZ20011358A patent/CZ20011358A3/cs unknown
- 1999-10-26 DE DE69938666T patent/DE69938666D1/de not_active Expired - Lifetime
- 1999-10-26 BR BR9914835-8A patent/BR9914835A/pt not_active IP Right Cessation
- 1999-10-26 PL PL99347553A patent/PL347553A1/xx not_active Application Discontinuation
- 1999-10-26 CN CN99812722A patent/CN1324405A/zh active Pending
- 1999-10-26 WO PCT/JP1999/005905 patent/WO2000024890A1/ja not_active Ceased
- 1999-10-26 CA CA002347294A patent/CA2347294A1/en not_active Abandoned
- 1999-10-26 SK SK550-2001A patent/SK5502001A3/sk unknown
- 1999-10-26 AU AU62306/99A patent/AU6230699A/en not_active Abandoned
- 1999-10-26 HU HU0104937A patent/HUP0104937A2/hu unknown
- 1999-10-26 KR KR1020017005344A patent/KR20010085974A/ko not_active Withdrawn
- 1999-10-26 AT AT99949421T patent/ATE394485T1/de not_active IP Right Cessation
- 1999-10-27 ID IDW20010936A patent/ID28288A/id unknown
-
2001
- 2001-04-26 NO NO20012059A patent/NO20012059L/no not_active Application Discontinuation
-
2004
- 2004-02-05 US US10/771,417 patent/US7314754B2/en not_active Expired - Fee Related
-
2007
- 2007-10-24 US US11/976,414 patent/US7608409B2/en not_active Expired - Fee Related
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