JOP20080499B1 - تراكيب صيدلية تعتمد على هيكليات فوقية للمواد المضادة لمستقبلات الانجيوتنسين ومثبطات الاندوبيبتيداز المتعادلة - Google Patents

تراكيب صيدلية تعتمد على هيكليات فوقية للمواد المضادة لمستقبلات الانجيوتنسين ومثبطات الاندوبيبتيداز المتعادلة

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Publication number
JOP20080499B1
JOP20080499B1 JOP/2008/0499A JOP20080499A JOP20080499B1 JO P20080499 B1 JOP20080499 B1 JO P20080499B1 JO P20080499 A JOP20080499 A JO P20080499A JO P20080499 B1 JOP20080499 B1 JO P20080499B1
Authority
JO
Jordan
Prior art keywords
superstructures
arb
nep
blocker
inhibitor
Prior art date
Application number
JOP/2008/0499A
Other languages
English (en)
Inventor
Ruegger Colleen
Hul Jiahui
Kumaraperumal Natrajan
Aina Zannou Erika
Edward Royce Alan
Al-Fayoumi Suliman
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40451030&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JOP20080499(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of JOP20080499B1 publication Critical patent/JOP20080499B1/ar

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

يتعلق هذا الاختراع صور جرعه فمية صلبة، وبصفة خاصة اقراص، من تركيب صيدلي يتضمن معقد كبير الجزئيات يمكن ان يكون بعملية الكبس المباشر او عملية الضغط مثل الضغط باللف، بشكل جرعه فمية صلبة خصائص تحرير وقتي والتي تسمجح بالاطلاق السريع للعامل العلاجي، ويكون المعقد الكبير الجزئيات المفيد بصفو خاصة عبارة عن ثلاثي الصوديوم [3- ( is, 3r) -1- ثنائي الفنيل-4- اثيل مثيل-3- ايثوكسي كربونيل -1- بيوتيل كربامويل) بروبيونات ( S) -3- مثيل-2- ( بينتانويل {2andquot; ( تترازول -5- يات) ثنائي الفنيل -4andquot; اثيل مثيل} امينو) بيوتيرات] نصف خماسي هيدرات
JOP/2008/0499A 2007-11-06 2008-11-04 تراكيب صيدلية تعتمد على هيكليات فوقية للمواد المضادة لمستقبلات الانجيوتنسين ومثبطات الاندوبيبتيداز المتعادلة JOP20080499B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98566807P 2007-11-06 2007-11-06

Publications (1)

Publication Number Publication Date
JOP20080499B1 true JOP20080499B1 (ar) 2022-09-15

Family

ID=40451030

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2008/0499A JOP20080499B1 (ar) 2007-11-06 2008-11-04 تراكيب صيدلية تعتمد على هيكليات فوقية للمواد المضادة لمستقبلات الانجيوتنسين ومثبطات الاندوبيبتيداز المتعادلة

Country Status (34)

Country Link
US (3) US20100267786A1 (ar)
EP (4) EP2295035B1 (ar)
JP (2) JP5653218B2 (ar)
KR (2) KR101700062B1 (ar)
CN (2) CN103251587A (ar)
AR (1) AR069184A1 (ar)
AU (1) AU2008324878B2 (ar)
BR (1) BRPI0823505A2 (ar)
CA (1) CA2703598C (ar)
CL (1) CL2008003298A1 (ar)
CY (2) CY1116280T1 (ar)
DK (3) DK2217205T3 (ar)
EC (1) ECSP10010160A (ar)
ES (3) ES2536514T3 (ar)
FI (1) FI3067043T3 (ar)
GT (1) GT201000131A (ar)
HK (3) HK1143529A1 (ar)
HR (3) HRP20230178T3 (ar)
HU (2) HUE028866T2 (ar)
IL (3) IL262990B2 (ar)
JO (1) JOP20080499B1 (ar)
MA (1) MA31797B1 (ar)
MX (1) MX2010004930A (ar)
MY (1) MY153730A (ar)
NZ (1) NZ584686A (ar)
PE (2) PE20141072A1 (ar)
PL (3) PL2295035T3 (ar)
PT (3) PT2295035T (ar)
RU (1) RU2493844C3 (ar)
SG (1) SG185951A1 (ar)
SI (3) SI3067043T1 (ar)
TN (1) TN2010000200A1 (ar)
TW (1) TWI484982B (ar)
WO (1) WO2009061713A1 (ar)

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EP1897537A1 (en) * 2006-09-04 2008-03-12 Novartis AG Composition comprising an angiotensin II receptor antagonist
HRP20230178T3 (hr) 2007-11-06 2023-03-31 Novartis Ag Farmaceutski pripravci temeljeni na nadgradnjama antagonista/blokatora angiotenzinskog receptora (arb) i inhibitoru neutralne endopeptidaze (nep)

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