IT1256616B - SYRUP CONTAINING N-ACETYL-CISTEIN - Google Patents

SYRUP CONTAINING N-ACETYL-CISTEIN

Info

Publication number
IT1256616B
IT1256616B ITMI922758A ITMI922758A IT1256616B IT 1256616 B IT1256616 B IT 1256616B IT MI922758 A ITMI922758 A IT MI922758A IT MI922758 A ITMI922758 A IT MI922758A IT 1256616 B IT1256616 B IT 1256616B
Authority
IT
Italy
Prior art keywords
acetyl
syrup containing
cistein
solution
viscosant
Prior art date
Application number
ITMI922758A
Other languages
Italian (it)
Inventor
Federico Stroppolo
Daniele Bonadeo
Annibale Gazzaniga
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ITMI922758A0 publication Critical patent/ITMI922758A0/en
Priority to ITMI922758A priority Critical patent/IT1256616B/en
Priority to UA95062994A priority patent/UA27142C2/en
Priority to PCT/EP1993/003280 priority patent/WO1994012168A1/en
Priority to ES09450021A priority patent/ES2070806B1/en
Priority to NL9320052A priority patent/NL194957C/en
Priority to DE4396086T priority patent/DE4396086T1/en
Priority to CH2423/94A priority patent/CH685371A5/en
Priority to HU9501586A priority patent/HU221484B/en
Priority to RU95114406A priority patent/RU2108777C1/en
Priority to DE4396086A priority patent/DE4396086B3/en
Priority to AT0906093A priority patent/AT407113B/en
Priority to NZ258544A priority patent/NZ258544A/en
Priority to CA002150462A priority patent/CA2150462C/en
Priority to AU56266/94A priority patent/AU667611B2/en
Priority to CZ951367A priority patent/CZ282550B6/en
Priority to JP6512747A priority patent/JPH08503703A/en
Priority to MD96-0265A priority patent/MD1714G2/en
Priority to GB9509822A priority patent/GB2288977B/en
Priority to BE9301326A priority patent/BE1006799A3/en
Priority to FR9314443A priority patent/FR2698545B1/en
Priority to LU88618A priority patent/LU88618A1/en
Publication of ITMI922758A1 publication Critical patent/ITMI922758A1/en
Priority to DK199500614A priority patent/DK176247B1/en
Priority to SE9502001A priority patent/SE520834C2/en
Priority to NO19952183A priority patent/NO314018B1/en
Priority to HU95P/P00579P priority patent/HU211912A9/en
Application granted granted Critical
Publication of IT1256616B publication Critical patent/IT1256616B/en
Priority to US08/867,923 priority patent/US5807894A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/12Mucolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

Uno sciroppo contenente N-acetil-cisteina, stabile per almeno due anni, di gusto ed odore gradevole, è costituito da una soluzione acquosa di NAC, un edulcorante ed un viscosante. La soluzione può inoltre contenere un aroma ed un conservante. Il pH è compreso tra 5 ed 8.A syrup containing N-acetyl-cysteine, stable for at least two years, with a pleasant taste and odor, is made up of an aqueous solution of NAC, a sweetener and a viscosant. The solution may also contain an aroma and a preservative. The pH is between 5 and 8.

ITMI922758A 1992-12-02 1992-12-02 SYRUP CONTAINING N-ACETYL-CISTEIN IT1256616B (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
ITMI922758A IT1256616B (en) 1992-12-02 1992-12-02 SYRUP CONTAINING N-ACETYL-CISTEIN
CA002150462A CA2150462C (en) 1992-12-02 1993-11-23 Syrup containing n-acetyl-cysteine
CZ951367A CZ282550B6 (en) 1992-12-02 1993-11-23 Preparation in the form of syrup and containing n-acetylcysteine
ES09450021A ES2070806B1 (en) 1992-12-02 1993-11-23 SYRUP CONTAINING N-ACETYL-CYSTEINE.
NL9320052A NL194957C (en) 1992-12-02 1993-11-23 N-acetyl-cysteine-containing syrup.
DE4396086T DE4396086T1 (en) 1992-12-02 1993-11-23 Syrup with N-acetylcysteine
CH2423/94A CH685371A5 (en) 1992-12-02 1993-11-23 Syrup contg. N-acetyl cysteine for treating colds
HU9501586A HU221484B (en) 1992-12-02 1993-11-23 Syrup containing n-acetyl-cysteine
RU95114406A RU2108777C1 (en) 1992-12-02 1993-11-23 Curative composition as a syrup
DE4396086A DE4396086B3 (en) 1992-12-02 1993-11-23 Syrup with N-acetylcysteine
AT0906093A AT407113B (en) 1992-12-02 1993-11-23 COMPOSITION IN THE FORM OF AN AQUEOUS THICKENED PREPARATION FOR PERORAL ADMINISTRATION WITH N-ACETYLCYSTONE
NZ258544A NZ258544A (en) 1992-12-02 1993-11-23 Time-stable aqueous syrup containing n-acetyl cysteine
UA95062994A UA27142C2 (en) 1992-12-02 1993-11-23 Pharmaceutical composition
AU56266/94A AU667611B2 (en) 1992-12-02 1993-11-23 Syrup containing N-acetyl-cysteine
PCT/EP1993/003280 WO1994012168A1 (en) 1992-12-02 1993-11-23 Syrup containing n-acetyl-cysteine
JP6512747A JPH08503703A (en) 1992-12-02 1993-11-23 Syrup containing N-acetyl cysteine
MD96-0265A MD1714G2 (en) 1992-12-02 1993-11-23 Therapeutical composition in the form of syrup, containing N-acetylcysteine
GB9509822A GB2288977B (en) 1992-12-02 1993-11-23 Stable sweetened solutions of N-acetyl-cysteine
BE9301326A BE1006799A3 (en) 1992-12-02 1993-12-01 Syrup containing n-acetyl-cysteine.
FR9314443A FR2698545B1 (en) 1992-12-02 1993-12-02 SYRUP CONTAINING N-ACETYL-CYSTEINE.
LU88618A LU88618A1 (en) 1992-12-02 1994-05-24 Syrup with N-acetylcysteine
DK199500614A DK176247B1 (en) 1992-12-02 1995-05-31 Syrup containing N-acetylcysteine
SE9502001A SE520834C2 (en) 1992-12-02 1995-06-01 Syrup containing N-acetylcysteine
NO19952183A NO314018B1 (en) 1992-12-02 1995-06-01 Syrup containing N-acetyl-cysteine
HU95P/P00579P HU211912A9 (en) 1992-12-02 1995-06-29 Syrup containing n-acetyl-cysteine
US08/867,923 US5807894A (en) 1992-12-02 1997-06-03 Syrup containing N-acetyl-cysteine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922758A IT1256616B (en) 1992-12-02 1992-12-02 SYRUP CONTAINING N-ACETYL-CISTEIN

Publications (3)

Publication Number Publication Date
ITMI922758A0 ITMI922758A0 (en) 1992-12-02
ITMI922758A1 ITMI922758A1 (en) 1994-06-02
IT1256616B true IT1256616B (en) 1995-12-12

Family

ID=11364395

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI922758A IT1256616B (en) 1992-12-02 1992-12-02 SYRUP CONTAINING N-ACETYL-CISTEIN

Country Status (23)

Country Link
JP (1) JPH08503703A (en)
AT (1) AT407113B (en)
AU (1) AU667611B2 (en)
BE (1) BE1006799A3 (en)
CA (1) CA2150462C (en)
CH (1) CH685371A5 (en)
CZ (1) CZ282550B6 (en)
DE (2) DE4396086B3 (en)
DK (1) DK176247B1 (en)
ES (1) ES2070806B1 (en)
FR (1) FR2698545B1 (en)
GB (1) GB2288977B (en)
HU (2) HU221484B (en)
IT (1) IT1256616B (en)
LU (1) LU88618A1 (en)
MD (1) MD1714G2 (en)
NL (1) NL194957C (en)
NO (1) NO314018B1 (en)
NZ (1) NZ258544A (en)
RU (1) RU2108777C1 (en)
SE (1) SE520834C2 (en)
UA (1) UA27142C2 (en)
WO (1) WO1994012168A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU704481B2 (en) * 1994-06-23 1999-04-22 Textile Research Institute Inc Topical compositions comprising N-acetyl-L-cysteine
JP4501023B2 (en) * 2002-11-14 2010-07-14 小林製薬株式会社 Composition with reduced bitterness and odor of cysteines
JP4501024B2 (en) * 2002-11-14 2010-07-14 小林製薬株式会社 Composition with reduced bitterness and odor of cysteines
US8148356B2 (en) * 2005-08-24 2012-04-03 Cumberland Pharmaceuticals, Inc. Acetylcysteine composition and uses therefor
CN102233139B (en) * 2010-04-21 2012-09-05 重庆健能医药开发有限公司 Acetylcysteine effervescent tablet and preparation method and application thereof
RU2611411C1 (en) * 2016-01-11 2017-02-21 Общество с ограниченной ответственностью "Трейдсервис" Dispersible in water acetylcysteine tablet and method of manufacturing thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB905197A (en) * 1960-01-01 1962-09-05 Lab Francais Chimiotherapie Anti-viral compositions comprising 1-phenyl-2-amino-propane-1,3-diol derivatives
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
BE901885A (en) * 1985-03-06 1985-07-01 Bruschettini Srl Stable ophthalmic soln. contg. N-acetyl-cysteine - prepd. in nitrogen satd. aq. buffer free of metal ions
CH666814A5 (en) * 1986-07-24 1988-08-31 Inpharzam Int Sa WATER-SOLUBLE PHARMACEUTICAL COMPOSITION CONTAINING N-ACETYL-CISTEIN.
CH667590A5 (en) * 1986-07-24 1988-10-31 Inpharzam Int Sa WATER-SOLUBLE EFFERVESCENT PHARMACEUTICAL COMPOSITION CONTAINING N-ACETYL-CISTEIN. .
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
CH674940A5 (en) * 1988-05-05 1990-08-15 Ibsa Inst Biochimique Sa
IT1234194B (en) * 1988-05-31 1992-05-06 Magis Farmaceutici SYRUP PHARMACEUTICAL COMPOSITIONS CONTAINING PENTITLES AS VEHICULATING AGENTS
EP0373103B1 (en) * 1988-11-10 1993-03-31 Ciba-Geigy Ag Liquid oral formulation
IT1231012B (en) * 1989-07-27 1991-11-08 Zambon Spa PHARMACEUTICAL COMPOSITION FOR ORAL USE CONTAINING NAC.
IT1248998B (en) * 1990-06-26 1995-02-11 Iscofar Sas COMPOSITION OF RUBBER TO BE CHEWED FOR THE PREVENTION AND TREATMENT OF DENTAL PLATE
DK0481294T4 (en) * 1990-10-19 2001-06-18 Spirig Ag Solid, fast-soluble drug preparation containing N-acetylcysteine

Also Published As

Publication number Publication date
DE4396086B3 (en) 2013-02-28
AU667611B2 (en) 1996-03-28
HU9501586D0 (en) 1995-08-28
HU211912A9 (en) 1996-01-29
NZ258544A (en) 1996-11-26
DK176247B1 (en) 2007-04-16
WO1994012168A1 (en) 1994-06-09
SE9502001D0 (en) 1995-06-01
NL194957B (en) 2003-05-01
GB2288977A (en) 1995-11-08
LU88618A1 (en) 1995-12-01
MD1714F2 (en) 2001-08-31
NO952183D0 (en) 1995-06-01
GB9509822D0 (en) 1995-07-19
BE1006799A3 (en) 1994-12-13
HU221484B (en) 2002-10-28
NO314018B1 (en) 2003-01-20
AT407113B (en) 2000-12-27
RU2108777C1 (en) 1998-04-20
SE9502001L (en) 1995-07-21
CZ282550B6 (en) 1997-08-13
ES2070806B1 (en) 1996-01-01
UA27142C2 (en) 2000-02-28
ATA906093A (en) 2000-05-15
ITMI922758A0 (en) 1992-12-02
FR2698545B1 (en) 1995-08-04
CA2150462A1 (en) 1994-06-09
DK61495A (en) 1995-05-31
FR2698545A1 (en) 1994-06-03
NL194957C (en) 2003-09-02
ES2070806A1 (en) 1995-06-01
HUT72668A (en) 1996-05-28
CA2150462C (en) 2005-04-19
GB2288977B (en) 1996-09-04
MD1714G2 (en) 2002-03-31
AU5626694A (en) 1994-06-22
ITMI922758A1 (en) 1994-06-02
SE520834C2 (en) 2003-09-02
NO952183L (en) 1995-06-01
DE4396086T1 (en) 1995-12-07
CH685371A5 (en) 1995-06-30
CZ136795A3 (en) 1995-11-15
NL9320052A (en) 1995-08-01
JPH08503703A (en) 1996-04-23

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971124