GB2288977B - Stable sweetened solutions of N-acetyl-cysteine - Google Patents

Stable sweetened solutions of N-acetyl-cysteine

Info

Publication number
GB2288977B
GB2288977B GB9509822A GB9509822A GB2288977B GB 2288977 B GB2288977 B GB 2288977B GB 9509822 A GB9509822 A GB 9509822A GB 9509822 A GB9509822 A GB 9509822A GB 2288977 B GB2288977 B GB 2288977B
Authority
GB
United Kingdom
Prior art keywords
cysteine
acetyl
stable
solutions
sweetened solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB9509822A
Other versions
GB9509822D0 (en
GB2288977A (en
Inventor
Federico Stroppolo
Daniele Bonadeo
Alessandro Saudino
Annibale Gazzaniga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Publication of GB9509822D0 publication Critical patent/GB9509822D0/en
Publication of GB2288977A publication Critical patent/GB2288977A/en
Application granted granted Critical
Publication of GB2288977B publication Critical patent/GB2288977B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
GB9509822A 1992-12-02 1993-11-23 Stable sweetened solutions of N-acetyl-cysteine Expired - Lifetime GB2288977B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI922758A IT1256616B (en) 1992-12-02 1992-12-02 SYRUP CONTAINING N-ACETYL-CISTEIN
PCT/EP1993/003280 WO1994012168A1 (en) 1992-12-02 1993-11-23 Syrup containing n-acetyl-cysteine

Publications (3)

Publication Number Publication Date
GB9509822D0 GB9509822D0 (en) 1995-07-19
GB2288977A GB2288977A (en) 1995-11-08
GB2288977B true GB2288977B (en) 1996-09-04

Family

ID=11364395

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9509822A Expired - Lifetime GB2288977B (en) 1992-12-02 1993-11-23 Stable sweetened solutions of N-acetyl-cysteine

Country Status (23)

Country Link
JP (1) JPH08503703A (en)
AT (1) AT407113B (en)
AU (1) AU667611B2 (en)
BE (1) BE1006799A3 (en)
CA (1) CA2150462C (en)
CH (1) CH685371A5 (en)
CZ (1) CZ282550B6 (en)
DE (2) DE4396086T1 (en)
DK (1) DK176247B1 (en)
ES (1) ES2070806B1 (en)
FR (1) FR2698545B1 (en)
GB (1) GB2288977B (en)
HU (2) HU221484B (en)
IT (1) IT1256616B (en)
LU (1) LU88618A1 (en)
MD (1) MD1714G2 (en)
NL (1) NL194957C (en)
NO (1) NO314018B1 (en)
NZ (1) NZ258544A (en)
RU (1) RU2108777C1 (en)
SE (1) SE520834C2 (en)
UA (1) UA27142C2 (en)
WO (1) WO1994012168A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT766557E (en) * 1994-06-23 2002-05-31 Procter & Gamble APPLICATION COMPOSITIONS TOPIC COMPREHENDING N-ACETYL-CYSTEIN
JP4501023B2 (en) * 2002-11-14 2010-07-14 小林製薬株式会社 Composition with reduced bitterness and odor of cysteines
JP4501024B2 (en) * 2002-11-14 2010-07-14 小林製薬株式会社 Composition with reduced bitterness and odor of cysteines
US8148356B2 (en) * 2005-08-24 2012-04-03 Cumberland Pharmaceuticals, Inc. Acetylcysteine composition and uses therefor
CN102233139B (en) * 2010-04-21 2012-09-05 重庆健能医药开发有限公司 Acetylcysteine effervescent tablet and preparation method and application thereof
RU2611411C1 (en) * 2016-01-11 2017-02-21 Общество с ограниченной ответственностью "Трейдсервис" Dispersible in water acetylcysteine tablet and method of manufacturing thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2192790A (en) * 1986-07-24 1988-01-27 Inpharzam Int Sa Acetylcysteine compositions
GB2192789A (en) * 1986-07-24 1988-01-27 Inpharzam Int Sa Acetylcysteine compositions
FR2631831A1 (en) * 1988-05-31 1989-12-01 Calco Anstalt Syrups based on xylitol, ribitol or arabitol
GB2234171A (en) * 1989-07-27 1991-01-30 Zambon Spa Composition containing N-acetyl-cysteine of enhanced bioavailability

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB905197A (en) * 1960-01-01 1962-09-05 Lab Francais Chimiotherapie Anti-viral compositions comprising 1-phenyl-2-amino-propane-1,3-diol derivatives
CA1239349A (en) * 1983-10-10 1988-07-19 Eberhard F. Gottwald Pharmaceutical composition containing cimetidine
BE901885A (en) * 1985-03-06 1985-07-01 Bruschettini Srl Stable ophthalmic soln. contg. N-acetyl-cysteine - prepd. in nitrogen satd. aq. buffer free of metal ions
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
CH674940A5 (en) * 1988-05-05 1990-08-15 Ibsa Inst Biochimique Sa
ATE87476T1 (en) * 1988-11-10 1993-04-15 Ciba Geigy Ag LIQUID ORAL FORMULATION.
IT1248998B (en) * 1990-06-26 1995-02-11 Iscofar Sas COMPOSITION OF RUBBER TO BE CHEWED FOR THE PREVENTION AND TREATMENT OF DENTAL PLATE
ES2077757T5 (en) * 1990-10-19 2001-06-01 Spirig Ag Pharmazeutische Prap SOLID PHARMACEUTICAL PREPARATION WITH QUICK DISSOLUTION CONTAINING N-ACETYLCISTEINE.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2192790A (en) * 1986-07-24 1988-01-27 Inpharzam Int Sa Acetylcysteine compositions
GB2192789A (en) * 1986-07-24 1988-01-27 Inpharzam Int Sa Acetylcysteine compositions
FR2631831A1 (en) * 1988-05-31 1989-12-01 Calco Anstalt Syrups based on xylitol, ribitol or arabitol
GB2234171A (en) * 1989-07-27 1991-01-30 Zambon Spa Composition containing N-acetyl-cysteine of enhanced bioavailability

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemical Abstract No. 102:225949 & Farm. Tidj. Belg. 61, (1984), pages 445-448 *

Also Published As

Publication number Publication date
BE1006799A3 (en) 1994-12-13
CA2150462A1 (en) 1994-06-09
ES2070806A1 (en) 1995-06-01
SE9502001D0 (en) 1995-06-01
HUT72668A (en) 1996-05-28
HU211912A9 (en) 1996-01-29
MD1714G2 (en) 2002-03-31
DK61495A (en) 1995-05-31
CZ136795A3 (en) 1995-11-15
JPH08503703A (en) 1996-04-23
CZ282550B6 (en) 1997-08-13
CA2150462C (en) 2005-04-19
NO314018B1 (en) 2003-01-20
HU9501586D0 (en) 1995-08-28
NL9320052A (en) 1995-08-01
ES2070806B1 (en) 1996-01-01
AU667611B2 (en) 1996-03-28
LU88618A1 (en) 1995-12-01
HU221484B (en) 2002-10-28
DK176247B1 (en) 2007-04-16
UA27142C2 (en) 2000-02-28
SE9502001L (en) 1995-07-21
ATA906093A (en) 2000-05-15
DE4396086B3 (en) 2013-02-28
SE520834C2 (en) 2003-09-02
ITMI922758A0 (en) 1992-12-02
NZ258544A (en) 1996-11-26
WO1994012168A1 (en) 1994-06-09
AT407113B (en) 2000-12-27
AU5626694A (en) 1994-06-22
NO952183D0 (en) 1995-06-01
GB9509822D0 (en) 1995-07-19
DE4396086T1 (en) 1995-12-07
GB2288977A (en) 1995-11-08
NL194957C (en) 2003-09-02
FR2698545A1 (en) 1994-06-03
FR2698545B1 (en) 1995-08-04
IT1256616B (en) 1995-12-12
CH685371A5 (en) 1995-06-30
MD1714F2 (en) 2001-08-31
NO952183L (en) 1995-06-01
RU2108777C1 (en) 1998-04-20
ITMI922758A1 (en) 1994-06-02
NL194957B (en) 2003-05-01

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20131122