IT1205031B - Derivati dell' etere immidazochinolinilico ad azione farmaceutica e procedimento per la loro preparazione - Google Patents

Derivati dell' etere immidazochinolinilico ad azione farmaceutica e procedimento per la loro preparazione

Info

Publication number
IT1205031B
IT1205031B IT20650/87A IT2065087A IT1205031B IT 1205031 B IT1205031 B IT 1205031B IT 20650/87 A IT20650/87 A IT 20650/87A IT 2065087 A IT2065087 A IT 2065087A IT 1205031 B IT1205031 B IT 1205031B
Authority
IT
Italy
Prior art keywords
immidazokinolinyl
procedure
preparation
ether derivatives
pharmaceutical action
Prior art date
Application number
IT20650/87A
Other languages
English (en)
Italian (it)
Other versions
IT8720650A0 (it
Inventor
Nicholas Meanwell
John J Wright
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8720650A0 publication Critical patent/IT8720650A0/it
Application granted granted Critical
Publication of IT1205031B publication Critical patent/IT1205031B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT20650/87A 1986-05-23 1987-05-22 Derivati dell' etere immidazochinolinilico ad azione farmaceutica e procedimento per la loro preparazione IT1205031B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/866,813 US4775674A (en) 1986-05-23 1986-05-23 Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors

Publications (2)

Publication Number Publication Date
IT8720650A0 IT8720650A0 (it) 1987-05-22
IT1205031B true IT1205031B (it) 1989-03-10

Family

ID=25348473

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20650/87A IT1205031B (it) 1986-05-23 1987-05-22 Derivati dell' etere immidazochinolinilico ad azione farmaceutica e procedimento per la loro preparazione

Country Status (24)

Country Link
US (1) US4775674A (cg-RX-API-DMAC7.html)
JP (1) JPS62283972A (cg-RX-API-DMAC7.html)
KR (1) KR900008567B1 (cg-RX-API-DMAC7.html)
AT (1) AT392790B (cg-RX-API-DMAC7.html)
AU (1) AU603577B2 (cg-RX-API-DMAC7.html)
BE (1) BE1002033A4 (cg-RX-API-DMAC7.html)
CA (1) CA1289137C (cg-RX-API-DMAC7.html)
CH (1) CH675246A5 (cg-RX-API-DMAC7.html)
DE (1) DE3717291A1 (cg-RX-API-DMAC7.html)
DK (1) DK166084C (cg-RX-API-DMAC7.html)
ES (1) ES2005588A6 (cg-RX-API-DMAC7.html)
FI (1) FI86723C (cg-RX-API-DMAC7.html)
FR (1) FR2603586B1 (cg-RX-API-DMAC7.html)
GB (1) GB2190676B (cg-RX-API-DMAC7.html)
GR (1) GR870803B (cg-RX-API-DMAC7.html)
HU (1) HU197570B (cg-RX-API-DMAC7.html)
IL (1) IL82612A0 (cg-RX-API-DMAC7.html)
IT (1) IT1205031B (cg-RX-API-DMAC7.html)
LU (1) LU86896A1 (cg-RX-API-DMAC7.html)
NL (1) NL8701226A (cg-RX-API-DMAC7.html)
NZ (1) NZ220345A (cg-RX-API-DMAC7.html)
PT (1) PT84938B (cg-RX-API-DMAC7.html)
SE (1) SE465163B (cg-RX-API-DMAC7.html)
ZA (1) ZA873583B (cg-RX-API-DMAC7.html)

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PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5187188A (en) * 1992-04-03 1993-02-16 Bristol-Myers Squibb Company Oxazole carboxylic acid derivatives
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
TW593317B (en) 1993-06-21 2004-06-21 Janssen Pharmaceutica Nv Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
US6573273B1 (en) 1999-06-10 2003-06-03 3M Innovative Properties Company Urea substituted imidazoquinolines
US6331539B1 (en) 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
US6541485B1 (en) 1999-06-10 2003-04-01 3M Innovative Properties Company Urea substituted imidazoquinolines
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US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
CN1906193A (zh) 2003-11-14 2007-01-31 3M创新有限公司 肟取代的咪唑环化合物
EP1682544A4 (en) 2003-11-14 2009-05-06 3M Innovative Properties Co HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS
SG148201A1 (en) 2003-11-25 2008-12-31 3M Innovative Properties Co Substituted imidazo ring systems and methods
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
WO2005066169A2 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
CA2559863A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
US7943609B2 (en) 2004-12-30 2011-05-17 3M Innovative Proprerties Company Chiral fused [1,2]imidazo[4,5-C] ring compounds
JP5313502B2 (ja) 2004-12-30 2013-10-09 スリーエム イノベイティブ プロパティズ カンパニー 置換キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
WO2006086634A2 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
WO2006107853A2 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2275096A3 (en) 2005-08-26 2011-07-13 Braincells, Inc. Neurogenesis via modulation of the muscarinic receptors
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249435A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 HT receptor mediated neurogenesis
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
PL2583970T3 (pl) 2006-08-02 2016-05-31 Cytokinetics Inc Określone cząstki chemiczne, kompozycje i sposoby zawierające imidazopirymidyny
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
EP2139478A4 (en) * 2007-03-30 2010-05-05 Cytokinetics Inc CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
PH12014500094A1 (en) 2011-07-13 2014-03-17 Cytokinetics Inc Combination als therapy
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
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Also Published As

Publication number Publication date
DK263587D0 (da) 1987-05-22
DK263587A (da) 1987-11-24
GB2190676B (en) 1990-05-30
NL8701226A (nl) 1987-12-16
GB2190676A (en) 1987-11-25
FR2603586B1 (fr) 1990-12-28
IL82612A0 (en) 1987-11-30
ES2005588A6 (es) 1989-03-16
FI86723B (fi) 1992-06-30
FI872220L (fi) 1987-11-24
CH675246A5 (cg-RX-API-DMAC7.html) 1990-09-14
DK166084C (da) 1993-08-02
BE1002033A4 (fr) 1990-05-29
FI872220A0 (fi) 1987-05-20
PT84938A (en) 1987-06-01
SE465163B (sv) 1991-08-05
GB8711839D0 (en) 1987-06-24
AU603577B2 (en) 1990-11-22
DE3717291A1 (de) 1987-11-26
CA1289137C (en) 1991-09-17
ATA132087A (de) 1990-11-15
IT8720650A0 (it) 1987-05-22
FR2603586A1 (fr) 1988-03-11
HU197570B (en) 1989-04-28
FI86723C (fi) 1992-10-12
SE8702158L (sv) 1987-11-24
HUT43602A (en) 1987-11-30
KR900008567B1 (ko) 1990-11-24
ZA873583B (en) 1988-04-27
NZ220345A (en) 1990-10-26
GR870803B (en) 1987-09-24
DK166084B (da) 1993-03-08
PT84938B (pt) 1990-02-08
LU86896A1 (fr) 1988-01-20
AT392790B (de) 1991-06-10
US4775674A (en) 1988-10-04
KR870011137A (ko) 1987-12-21
SE8702158D0 (sv) 1987-05-22
JPS62283972A (ja) 1987-12-09
AU7299387A (en) 1987-11-26

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