IT8720650A0 - Derivati dell'etere immidazochinolinilico ad azione farmaceutica e procedimento per laloro preparazione. - Google Patents

Derivati dell'etere immidazochinolinilico ad azione farmaceutica e procedimento per laloro preparazione.

Info

Publication number
IT8720650A0
IT8720650A0 IT8720650A IT2065087A IT8720650A0 IT 8720650 A0 IT8720650 A0 IT 8720650A0 IT 8720650 A IT8720650 A IT 8720650A IT 2065087 A IT2065087 A IT 2065087A IT 8720650 A0 IT8720650 A0 IT 8720650A0
Authority
IT
Italy
Prior art keywords
immidazoquinolinylic
derivatives
ether
procedure
preparation
Prior art date
Application number
IT8720650A
Other languages
English (en)
Other versions
IT1205031B (it
Inventor
Nicholas Meanwell
John J Wright
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8720650A0 publication Critical patent/IT8720650A0/it
Application granted granted Critical
Publication of IT1205031B publication Critical patent/IT1205031B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT20650/87A 1986-05-23 1987-05-22 Derivati dell' etere immidazochinolinilico ad azione farmaceutica e procedimento per la loro preparazione IT1205031B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/866,813 US4775674A (en) 1986-05-23 1986-05-23 Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors

Publications (2)

Publication Number Publication Date
IT8720650A0 true IT8720650A0 (it) 1987-05-22
IT1205031B IT1205031B (it) 1989-03-10

Family

ID=25348473

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20650/87A IT1205031B (it) 1986-05-23 1987-05-22 Derivati dell' etere immidazochinolinilico ad azione farmaceutica e procedimento per la loro preparazione

Country Status (24)

Country Link
US (1) US4775674A (it)
JP (1) JPS62283972A (it)
KR (1) KR900008567B1 (it)
AT (1) AT392790B (it)
AU (1) AU603577B2 (it)
BE (1) BE1002033A4 (it)
CA (1) CA1289137C (it)
CH (1) CH675246A5 (it)
DE (1) DE3717291A1 (it)
DK (1) DK166084C (it)
ES (1) ES2005588A6 (it)
FI (1) FI86723C (it)
FR (1) FR2603586B1 (it)
GB (1) GB2190676B (it)
GR (1) GR870803B (it)
HU (1) HU197570B (it)
IL (1) IL82612A0 (it)
IT (1) IT1205031B (it)
LU (1) LU86896A1 (it)
NL (1) NL8701226A (it)
NZ (1) NZ220345A (it)
PT (1) PT84938B (it)
SE (1) SE465163B (it)
ZA (1) ZA873583B (it)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1306260C (en) * 1985-10-18 1992-08-11 Shionogi & Co., Ltd. Condensed imidazopyridine derivatives
JPH01189791A (ja) * 1988-01-26 1989-07-28 New Japan Radio Co Ltd 非接触ｉｄカード
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
US5262540A (en) * 1989-12-20 1993-11-16 Bristol-Myers Squibb Company [2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5187188A (en) * 1992-04-03 1993-02-16 Bristol-Myers Squibb Company Oxazole carboxylic acid derivatives
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
TW593317B (en) 1993-06-21 2004-06-21 Janssen Pharmaceutica Nv Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
US6756382B2 (en) 1999-06-10 2004-06-29 3M Innovative Properties Company Amide substituted imidazoquinolines
US6331539B1 (en) * 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
US6541485B1 (en) 1999-06-10 2003-04-01 3M Innovative Properties Company Urea substituted imidazoquinolines
US6573273B1 (en) 1999-06-10 2003-06-03 3M Innovative Properties Company Urea substituted imidazoquinolines
JP4767429B2 (ja) * 2001-03-02 2011-09-07 株式会社クラレ 架橋剤および架橋性重合体
MXPA05005661A (es) * 2002-11-27 2005-11-23 Artesian Therapeutics Inc Compuestos con actividad antagonista o antagonista parcial mixta inhibidora de fosfodiesterasa y beta-adrenergica para el tratamiento de insuficiencia cardiaca.
MXPA06001674A (es) 2003-08-12 2006-05-12 3M Innovative Properties Co Compuestos que contienen imidazo hidroxilamina-sustituidos.
BRPI0413998A (pt) 2003-08-27 2006-11-07 3M Innovative Properties Co imidazoquinolinas arilóxi e arilalquilenóxi substituìdas
AU2004270201A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
MXPA06003705A (es) 2003-10-03 2006-06-20 3M Innovative Properties Co Imidazoquinolinas sustituidas con alcoxi.
WO2005048933A2 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Oxime substituted imidazo ring compounds
CA2545825A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
US8691837B2 (en) 2003-11-25 2014-04-08 3M Innovative Properties Company Substituted imidazo ring systems and methods
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
AU2004312508A1 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
AU2005228150A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
EP1831221B1 (en) 2004-12-30 2012-08-08 3M Innovative Properties Company Substituted chiral fused 1,2 imidazo 4,5-c ring compounds
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
EP1844201B1 (en) 2005-02-04 2016-08-24 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
CA2597587A1 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
EP1869043A2 (en) 2005-04-01 2007-12-26 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
MX2009001170A (es) 2006-08-02 2009-05-21 Cytokinetics Inc Determinadas entidades quimicas, composiciones y metodos.
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
AU2007292848A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008121333A1 (en) * 2007-03-30 2008-10-09 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
AU2012281042B2 (en) 2011-07-13 2016-07-14 Cytokinetics, Inc. Combination ALS therapy
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
WO2024149378A1 (zh) * 2023-01-13 2024-07-18 上海超阳药业有限公司 喹啉酮化合物和萘啶酮化合物及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
NL7807507A (nl) * 1977-07-25 1979-01-29 Hoffmann La Roche Tricyclische verbindingen.
IL62402A0 (en) * 1980-03-24 1981-05-20 Sterling Drug Inc Imidazo(4,5-b)pyridines,their preparation and pharmaceutical compositions containing them
US4490371A (en) * 1983-02-16 1984-12-25 Syntex (U.S.A.) Inc. N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
JPS604186A (ja) * 1983-06-21 1985-01-10 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン化合物
JPS6028979A (ja) * 1983-07-14 1985-02-14 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン類化合物
IL74349A (en) * 1984-02-15 1988-07-31 Syntex Inc (2-oxo-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolinyl)-oxyalkylamides,their preparation and pharmaceutical compositions containing them
US4668686A (en) * 1985-04-25 1987-05-26 Bristol-Myers Company Imidazoquinoline antithrombrogenic cardiotonic agents

Also Published As

Publication number Publication date
SE8702158D0 (sv) 1987-05-22
GB2190676A (en) 1987-11-25
IT1205031B (it) 1989-03-10
DK166084B (da) 1993-03-08
GB8711839D0 (en) 1987-06-24
DK263587D0 (da) 1987-05-22
SE8702158L (sv) 1987-11-24
FI872220A (fi) 1987-11-24
PT84938A (en) 1987-06-01
HUT43602A (en) 1987-11-30
GB2190676B (en) 1990-05-30
KR900008567B1 (ko) 1990-11-24
AT392790B (de) 1991-06-10
FI86723B (fi) 1992-06-30
DK263587A (da) 1987-11-24
HU197570B (en) 1989-04-28
ATA132087A (de) 1990-11-15
GR870803B (en) 1987-09-24
NZ220345A (en) 1990-10-26
LU86896A1 (fr) 1988-01-20
CA1289137C (en) 1991-09-17
BE1002033A4 (fr) 1990-05-29
AU603577B2 (en) 1990-11-22
FR2603586B1 (fr) 1990-12-28
PT84938B (pt) 1990-02-08
FR2603586A1 (fr) 1988-03-11
KR870011137A (ko) 1987-12-21
FI872220A0 (fi) 1987-05-20
NL8701226A (nl) 1987-12-16
CH675246A5 (it) 1990-09-14
IL82612A0 (en) 1987-11-30
JPS62283972A (ja) 1987-12-09
AU7299387A (en) 1987-11-26
DE3717291A1 (de) 1987-11-26
ZA873583B (en) 1988-04-27
SE465163B (sv) 1991-08-05
DK166084C (da) 1993-08-02
US4775674A (en) 1988-10-04
FI86723C (fi) 1992-10-12
ES2005588A6 (es) 1989-03-16

Similar Documents

Publication Publication Date Title
IT8720650A0 (it) Derivati dell'etere immidazochinolinilico ad azione farmaceutica e procedimento per laloro preparazione.
IT8467445A1 (it) Composizione e preparato per la somministrazione di medicamenti per via cutanea.
NL300136I1 (nl) Farmacologisch actieve catecholderivaten en samenstellingen ervan.
IT1187717B (it) Procedimento per la preparazione di derivati 3-sostituiti dell'1-amino-2-idrossi-propano
IT8721691A0 (it) Derivati dell'ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide, loro procedimento di preparazione e loro impiegocome sostanze medicinali.
IT8747874A0 (it) La loro preparazione derivati tiodiossolanici ad attivita' moculitica e procedimento per
IT8121654A0 (it) Derivati tiazolidinici ad attivita' farmacologica, procedimento per la loro preparazione e composizioni farmaceutiche contenenti detti derivati.
IT8721687A0 (it) Derivati dell'ossima della 1,2,5,6-tetraidropiridin-3-carbossa ldeide, loro procedimento di preparazione e loro impiego come sostanze medicinali.
IT8320631A0 (it) Derivati n-carbammoilici dell'isotiazolo-(5,4b)piridin-one-3 e loro procedimentodi preparazione.
IT8449056A0 (it) Derivati dell'1,2-ditiolano,loro preparazione e loro impiego come medicamenti
IT8221801A0 (it) Derivati di 1, 2, 3,4-tetraidronaftalene, procedimentodi preparazione e relative composizioni farmaceutiche.
IT8347588A0 (it) Derivati dell'indolina, loro preparazione e loro impiego come medicamenti
IT8620756A0 (it) Procedimento per la preparazione di derivati n-allil-piperidinici.
IT8124627A0 (it) Procedimento per la preparazione di derivati dell' 11-dodecen-1-ile.
IT8103423A0 (it) Derivati di alcandioli conattivita' ipolipidemizzante, metodi per la loro preparazione e composizioni farmaceutiche che licontengono
IT8720271A0 (it) Nuovi derivati dell'ergolene, composizioni farmaceutiche che licontengono e procedimento per lapreparazione dei medesimi.
IT1167746B (it) Nitroimidazoli ad attivita' tricomonacida, procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1214436B (it) Derivati dell'eteroprostaglandina e procedimenti per la loro preparazione.
IT1148788B (it) Derivati dell'amminoisochinolina e procedimento per la loro preparazione
IT1148145B (it) Derivati azaspiroalcandionici dotati di attivita'psicotropica e procedimento per la loro preparazione
IT8321223A0 (it) Composizione farmaceutica acarattere di collirio ad azione antiinfiammatoria, e procedimento per la sua preparazione.
IT8520150A0 (it) Nuovi derivati ad attivita'terapeutica, procedimento per laloro preparazione e relative composizioni farmaceutiche.
IT8867820A0 (it) Procedimento di preparazione di derivati dell'1,4-benzodiazepina-4-one
IT8121181A0 (it) Procedimento per la preparazione di derivati della benzoil-alfa-mercapto-propionilglicina ad attivita' terapeutica.
IT1187729B (it) Derivati fenilpiridinici,loro preparazione e relative formulazioni farmaceutiche