IT1193755B - Derivati di benzimidazolo e benzimidazolidina con proprieta' diuretiche ed antiipertensive e procedimento di preparazione - Google Patents

Derivati di benzimidazolo e benzimidazolidina con proprieta' diuretiche ed antiipertensive e procedimento di preparazione

Info

Publication number
IT1193755B
IT1193755B IT48686/79A IT4868679A IT1193755B IT 1193755 B IT1193755 B IT 1193755B IT 48686/79 A IT48686/79 A IT 48686/79A IT 4868679 A IT4868679 A IT 4868679A IT 1193755 B IT1193755 B IT 1193755B
Authority
IT
Italy
Prior art keywords
benzimidazolidina
diuretic
benzimidazole
derivatives
preparation procedure
Prior art date
Application number
IT48686/79A
Other languages
English (en)
Italian (it)
Other versions
IT7948686A0 (it
Original Assignee
Mundipharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma Ag filed Critical Mundipharma Ag
Publication of IT7948686A0 publication Critical patent/IT7948686A0/it
Application granted granted Critical
Publication of IT1193755B publication Critical patent/IT1193755B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT48686/79A 1978-04-10 1979-04-10 Derivati di benzimidazolo e benzimidazolidina con proprieta' diuretiche ed antiipertensive e procedimento di preparazione IT1193755B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89504878A 1978-04-10 1978-04-10

Publications (2)

Publication Number Publication Date
IT7948686A0 IT7948686A0 (it) 1979-04-10
IT1193755B true IT1193755B (it) 1988-08-24

Family

ID=25403870

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48686/79A IT1193755B (it) 1978-04-10 1979-04-10 Derivati di benzimidazolo e benzimidazolidina con proprieta' diuretiche ed antiipertensive e procedimento di preparazione

Country Status (19)

Country Link
JP (1) JPS54138561A (fi)
AT (1) AT372951B (fi)
AU (1) AU531086B2 (fi)
BE (1) BE875425A (fi)
CA (1) CA1126280A (fi)
DE (1) DE2914084A1 (fi)
DK (1) DK139079A (fi)
ES (1) ES479446A1 (fi)
FI (1) FI74461C (fi)
FR (1) FR2422644A1 (fi)
GB (1) GB2018766B (fi)
GR (1) GR68483B (fi)
IL (1) IL57105A (fi)
IT (1) IT1193755B (fi)
NL (1) NL7902802A (fi)
NZ (1) NZ190136A (fi)
PT (1) PT69458A (fi)
SE (1) SE446532B (fi)
ZA (1) ZA791726B (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070466A (zh) * 2010-12-28 2011-05-25 天津市筠凯化工科技有限公司 5-氯-2-硝基苯胺制备方法
CN108558712A (zh) * 2018-06-20 2018-09-21 新乡市锦源化工有限公司 一种以乙酰苯胺为原料合成高纯度对氨基苯磺酰胺的方法及对氨基苯磺酰胺
CN110305018B (zh) * 2019-06-06 2022-07-15 浙江普洛家园药业有限公司 一种3-溴-2-氟硝基苯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH404675A (de) * 1961-06-29 1965-12-31 Siegfried Ag Verfahren zur Herstellung neuer heterocyclischer Sulfonamidoverbindungen
FR1469504A (fr) * 1964-10-22 1967-02-17 Fisons Pest Control Ltd Composés insecticides
FR1477792A (fr) * 1965-03-24 1967-04-21 Fisons Pest Control Ltd Nouveaux benzimidazoles
GB1163711A (en) * 1966-01-13 1969-09-10 Fisons Pest Control Ltd Substituted Benzimidazoles and Biocidally-Active Compositions
GB1356244A (en) * 1970-07-29 1974-06-12 Fisons Ltd Substituted benzimidazole parasiticides

Also Published As

Publication number Publication date
NL7902802A (nl) 1979-10-12
AU531086B2 (en) 1983-08-11
GR68483B (fi) 1982-01-04
ES479446A1 (es) 1979-08-01
FI74461C (fi) 1988-02-08
FI791083A (fi) 1979-10-11
NZ190136A (en) 1982-11-23
IL57105A0 (en) 1979-07-25
FI74461B (fi) 1987-10-30
DK139079A (da) 1979-10-11
DE2914084A1 (de) 1979-10-25
ZA791726B (en) 1980-05-28
AT372951B (de) 1983-12-12
SE7902911L (sv) 1979-10-11
GB2018766A (en) 1979-10-24
AU4567579A (en) 1979-10-18
SE446532B (sv) 1986-09-22
BE875425A (fr) 1979-07-31
CA1126280A (en) 1982-06-22
JPS54138561A (en) 1979-10-27
ATA263379A (de) 1983-04-15
FR2422644B1 (fi) 1982-12-17
PT69458A (en) 1979-05-01
IT7948686A0 (it) 1979-04-10
JPH0250904B2 (fi) 1990-11-05
GB2018766B (en) 1982-09-22
FR2422644A1 (fr) 1979-11-09
IL57105A (en) 1983-10-31

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