JPS54138561A - Benzoimidazole and benzoimidazolidine derivative having hypotensive and diuretic activity and its manufacture - Google Patents

Benzoimidazole and benzoimidazolidine derivative having hypotensive and diuretic activity and its manufacture

Info

Publication number
JPS54138561A
JPS54138561A JP4211979A JP4211979A JPS54138561A JP S54138561 A JPS54138561 A JP S54138561A JP 4211979 A JP4211979 A JP 4211979A JP 4211979 A JP4211979 A JP 4211979A JP S54138561 A JPS54138561 A JP S54138561A
Authority
JP
Japan
Prior art keywords
benzoimidazolidine
benzoimidazole
hypotensive
derivative
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4211979A
Other languages
Japanese (ja)
Other versions
JPH0250904B2 (en
Inventor
Bitaru Shietei Bora
Matsukufuaden Arutsuuru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mundipharma AG
Original Assignee
Mundipharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma AG filed Critical Mundipharma AG
Publication of JPS54138561A publication Critical patent/JPS54138561A/en
Publication of JPH0250904B2 publication Critical patent/JPH0250904B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP4211979A 1978-04-10 1979-04-09 Benzoimidazole and benzoimidazolidine derivative having hypotensive and diuretic activity and its manufacture Granted JPS54138561A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89504878A 1978-04-10 1978-04-10

Publications (2)

Publication Number Publication Date
JPS54138561A true JPS54138561A (en) 1979-10-27
JPH0250904B2 JPH0250904B2 (en) 1990-11-05

Family

ID=25403870

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4211979A Granted JPS54138561A (en) 1978-04-10 1979-04-09 Benzoimidazole and benzoimidazolidine derivative having hypotensive and diuretic activity and its manufacture

Country Status (19)

Country Link
JP (1) JPS54138561A (en)
AT (1) AT372951B (en)
AU (1) AU531086B2 (en)
BE (1) BE875425A (en)
CA (1) CA1126280A (en)
DE (1) DE2914084A1 (en)
DK (1) DK139079A (en)
ES (1) ES479446A1 (en)
FI (1) FI74461C (en)
FR (1) FR2422644A1 (en)
GB (1) GB2018766B (en)
GR (1) GR68483B (en)
IL (1) IL57105A (en)
IT (1) IT1193755B (en)
NL (1) NL7902802A (en)
NZ (1) NZ190136A (en)
PT (1) PT69458A (en)
SE (1) SE446532B (en)
ZA (1) ZA791726B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070466A (en) * 2010-12-28 2011-05-25 天津市筠凯化工科技有限公司 Preparation method of 5-chiorine-2-nitroaniline
CN108558712A (en) * 2018-06-20 2018-09-21 新乡市锦源化工有限公司 It is a kind of using antifebrin as the method and P-aminobenzene-sulfonamide of Material synthesis high-purity P-aminobenzene-sulfonamide
CN110305018B (en) * 2019-06-06 2022-07-15 浙江普洛家园药业有限公司 Preparation method of 3-bromo-2-fluoronitrobenzene

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH404675A (en) * 1961-06-29 1965-12-31 Siegfried Ag Process for the preparation of new heterocyclic sulfonamido compounds
FR1469504A (en) * 1964-10-22 1967-02-17 Fisons Pest Control Ltd Insecticidal compounds
FR1477792A (en) * 1965-03-24 1967-04-21 Fisons Pest Control Ltd New benzimidazoles
GB1163262A (en) * 1966-01-13 1969-09-04 Fisons Pest Control Ltd Substituted Benzimidazoles and Biocidally Active Compositions
GB1356244A (en) * 1970-07-29 1974-06-12 Fisons Ltd Substituted benzimidazole parasiticides

Also Published As

Publication number Publication date
IT1193755B (en) 1988-08-24
ES479446A1 (en) 1979-08-01
PT69458A (en) 1979-05-01
GB2018766A (en) 1979-10-24
SE7902911L (en) 1979-10-11
IL57105A0 (en) 1979-07-25
FI74461B (en) 1987-10-30
FI74461C (en) 1988-02-08
AU4567579A (en) 1979-10-18
AT372951B (en) 1983-12-12
NZ190136A (en) 1982-11-23
JPH0250904B2 (en) 1990-11-05
GR68483B (en) 1982-01-04
SE446532B (en) 1986-09-22
GB2018766B (en) 1982-09-22
ATA263379A (en) 1983-04-15
IT7948686A0 (en) 1979-04-10
FR2422644B1 (en) 1982-12-17
NL7902802A (en) 1979-10-12
AU531086B2 (en) 1983-08-11
CA1126280A (en) 1982-06-22
DE2914084A1 (en) 1979-10-25
DK139079A (en) 1979-10-11
ZA791726B (en) 1980-05-28
FI791083A (en) 1979-10-11
FR2422644A1 (en) 1979-11-09
IL57105A (en) 1983-10-31
BE875425A (en) 1979-07-31

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