JPS54117499A - 4*5 alphaaepoxymorphinanee66one compound* its manufacture and its pharmacological use - Google Patents

4*5 alphaaepoxymorphinanee66one compound* its manufacture and its pharmacological use

Info

Publication number
JPS54117499A
JPS54117499A JP1288479A JP1288479A JPS54117499A JP S54117499 A JPS54117499 A JP S54117499A JP 1288479 A JP1288479 A JP 1288479A JP 1288479 A JP1288479 A JP 1288479A JP S54117499 A JPS54117499 A JP S54117499A
Authority
JP
Japan
Prior art keywords
manufacture
compound
pharmacological use
pharmacological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1288479A
Other languages
Japanese (ja)
Other versions
JPS5757476B2 (en
Inventor
Nooman Shiyutsuto Robaato
Pooru Koteitsuku Maikeru
Roorensu Rerando Debitsudo
Odo Poratsutsui Jiyosefu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of JPS54117499A publication Critical patent/JPS54117499A/en
Publication of JPS5757476B2 publication Critical patent/JPS5757476B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP1288479A 1978-02-10 1979-02-08 4*5 alphaaepoxymorphinanee66one compound* its manufacture and its pharmacological use Granted JPS54117499A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87664078A 1978-02-10 1978-02-10
US91193978A 1978-06-02 1978-06-02

Publications (2)

Publication Number Publication Date
JPS54117499A true JPS54117499A (en) 1979-09-12
JPS5757476B2 JPS5757476B2 (en) 1982-12-04

Family

ID=27128411

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1288479A Granted JPS54117499A (en) 1978-02-10 1979-02-08 4*5 alphaaepoxymorphinanee66one compound* its manufacture and its pharmacological use

Country Status (7)

Country Link
JP (1) JPS54117499A (en)
AU (1) AU507873B2 (en)
CA (1) CA1106369A (en)
DE (1) DE2900918A1 (en)
FR (1) FR2424277A1 (en)
GB (1) GB2014141B (en)
IL (1) IL56222A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59500418A (en) * 1982-03-16 1984-03-15 ザ　ロツクフエラ−　ユニバ−シテイ How to recover from gastrointestinal dysfunction

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4259329A (en) * 1979-10-17 1981-03-31 Miles Laboratories, Inc. 17-Cyclobutylmethyl-3-hydroxy-β-methyl-6-methylene morphinane, and methods of treating pain with them
US4275205A (en) * 1980-05-05 1981-06-23 Miles Laboratories, Inc. 7,7-Ditosyloxymethyl-4,5α-epoxy-morphinan-6-ols
JPH0174251U (en) * 1987-11-02 1989-05-19
JPH043470U (en) * 1990-04-24 1992-01-13
US5194637A (en) * 1991-08-22 1993-03-16 Syracuse University Method and apparatus for synthesis of highly isomerically pure stereoisomers of glycidol derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1355143A (en) * 1963-04-05 1964-03-13 Shionogi & Co Morphinan derivatives and manufacturing process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59500418A (en) * 1982-03-16 1984-03-15 ザ　ロツクフエラ−　ユニバ−シテイ How to recover from gastrointestinal dysfunction
JPH045647B2 (en) * 1982-03-16 1992-02-03 Univ Rockefeller

Also Published As

Publication number Publication date
GB2014141B (en) 1982-09-15
FR2424277A1 (en) 1979-11-23
FR2424277B1 (en) 1982-03-12
AU4409079A (en) 1979-08-16
JPS5757476B2 (en) 1982-12-04
AU507873B2 (en) 1980-02-28
IL56222A (en) 1981-11-30
GB2014141A (en) 1979-08-22
IL56222A0 (en) 1979-03-12
DE2900918A1 (en) 1979-08-16
CA1106369A (en) 1981-08-04

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