AU4409079A - 8b-ethyl-and 8b-methyl-4,5x-epoxymorphinan-6-compounds - Google Patents

8b-ethyl-and 8b-methyl-4,5x-epoxymorphinan-6-compounds

Info

Publication number
AU4409079A
AU4409079A AU44090/79A AU4409079A AU4409079A AU 4409079 A AU4409079 A AU 4409079A AU 44090/79 A AU44090/79 A AU 44090/79A AU 4409079 A AU4409079 A AU 4409079A AU 4409079 A AU4409079 A AU 4409079A
Authority
AU
Australia
Prior art keywords
epoxymorphinan
ethyl
methyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU44090/79A
Other versions
AU507873B2 (en
Inventor
Michael Paul Kotick
David Lawrence Leland
Joseph Odo Polazzi
Robert Norman Schut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of AU4409079A publication Critical patent/AU4409079A/en
Application granted granted Critical
Publication of AU507873B2 publication Critical patent/AU507873B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU44090/79A 1978-02-10 1979-02-08 8b-ethyl-and 8b-methyl-4,5x-epoxymorphinan-6-compounds Ceased AU507873B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87664078A 1978-02-10 1978-02-10
US91193978A 1978-06-02 1978-06-02
US911939 1978-06-02
US876640 1997-06-16

Publications (2)

Publication Number Publication Date
AU4409079A true AU4409079A (en) 1979-08-16
AU507873B2 AU507873B2 (en) 1980-02-28

Family

ID=27128411

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44090/79A Ceased AU507873B2 (en) 1978-02-10 1979-02-08 8b-ethyl-and 8b-methyl-4,5x-epoxymorphinan-6-compounds

Country Status (7)

Country Link
JP (1) JPS54117499A (en)
AU (1) AU507873B2 (en)
CA (1) CA1106369A (en)
DE (1) DE2900918A1 (en)
FR (1) FR2424277A1 (en)
GB (1) GB2014141B (en)
IL (1) IL56222A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4259329A (en) * 1979-10-17 1981-03-31 Miles Laboratories, Inc. 17-Cyclobutylmethyl-3-hydroxy-β-methyl-6-methylene morphinane, and methods of treating pain with them
US4275205A (en) * 1980-05-05 1981-06-23 Miles Laboratories, Inc. 7,7-Ditosyloxymethyl-4,5α-epoxy-morphinan-6-ols
JPS59500418A (en) * 1982-03-16 1984-03-15 ザ　ロツクフエラ−　ユニバ−シテイ How to recover from gastrointestinal dysfunction
JPH0174251U (en) * 1987-11-02 1989-05-19
JPH043470U (en) * 1990-04-24 1992-01-13
US5194637A (en) * 1991-08-22 1993-03-16 Syracuse University Method and apparatus for synthesis of highly isomerically pure stereoisomers of glycidol derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1355143A (en) * 1963-04-05 1964-03-13 Shionogi & Co Morphinan derivatives and manufacturing process

Also Published As

Publication number Publication date
GB2014141B (en) 1982-09-15
FR2424277A1 (en) 1979-11-23
JPS54117499A (en) 1979-09-12
FR2424277B1 (en) 1982-03-12
JPS5757476B2 (en) 1982-12-04
AU507873B2 (en) 1980-02-28
IL56222A (en) 1981-11-30
GB2014141A (en) 1979-08-22
IL56222A0 (en) 1979-03-12
DE2900918A1 (en) 1979-08-16
CA1106369A (en) 1981-08-04

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