IT1193755B - BENZIMIDAZOLE AND BENZIMIDAZOLIDINA DERIVATIVES WITH DIURETIC AND ANTI-HYPERTENSIVE PROPERTIES AND PREPARATION PROCEDURE - Google Patents

BENZIMIDAZOLE AND BENZIMIDAZOLIDINA DERIVATIVES WITH DIURETIC AND ANTI-HYPERTENSIVE PROPERTIES AND PREPARATION PROCEDURE

Info

Publication number
IT1193755B
IT1193755B IT48686/79A IT4868679A IT1193755B IT 1193755 B IT1193755 B IT 1193755B IT 48686/79 A IT48686/79 A IT 48686/79A IT 4868679 A IT4868679 A IT 4868679A IT 1193755 B IT1193755 B IT 1193755B
Authority
IT
Italy
Prior art keywords
benzimidazolidina
diuretic
benzimidazole
derivatives
preparation procedure
Prior art date
Application number
IT48686/79A
Other languages
Italian (it)
Other versions
IT7948686A0 (en
Original Assignee
Mundipharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma Ag filed Critical Mundipharma Ag
Publication of IT7948686A0 publication Critical patent/IT7948686A0/en
Application granted granted Critical
Publication of IT1193755B publication Critical patent/IT1193755B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT48686/79A 1978-04-10 1979-04-10 BENZIMIDAZOLE AND BENZIMIDAZOLIDINA DERIVATIVES WITH DIURETIC AND ANTI-HYPERTENSIVE PROPERTIES AND PREPARATION PROCEDURE IT1193755B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89504878A 1978-04-10 1978-04-10

Publications (2)

Publication Number Publication Date
IT7948686A0 IT7948686A0 (en) 1979-04-10
IT1193755B true IT1193755B (en) 1988-08-24

Family

ID=25403870

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48686/79A IT1193755B (en) 1978-04-10 1979-04-10 BENZIMIDAZOLE AND BENZIMIDAZOLIDINA DERIVATIVES WITH DIURETIC AND ANTI-HYPERTENSIVE PROPERTIES AND PREPARATION PROCEDURE

Country Status (19)

Country Link
JP (1) JPS54138561A (en)
AT (1) AT372951B (en)
AU (1) AU531086B2 (en)
BE (1) BE875425A (en)
CA (1) CA1126280A (en)
DE (1) DE2914084A1 (en)
DK (1) DK139079A (en)
ES (1) ES479446A1 (en)
FI (1) FI74461C (en)
FR (1) FR2422644A1 (en)
GB (1) GB2018766B (en)
GR (1) GR68483B (en)
IL (1) IL57105A (en)
IT (1) IT1193755B (en)
NL (1) NL7902802A (en)
NZ (1) NZ190136A (en)
PT (1) PT69458A (en)
SE (1) SE446532B (en)
ZA (1) ZA791726B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070466A (en) * 2010-12-28 2011-05-25 天津市筠凯化工科技有限公司 Preparation method of 5-chiorine-2-nitroaniline
CN108558712A (en) * 2018-06-20 2018-09-21 新乡市锦源化工有限公司 It is a kind of using antifebrin as the method and P-aminobenzene-sulfonamide of Material synthesis high-purity P-aminobenzene-sulfonamide
CN110305018B (en) * 2019-06-06 2022-07-15 浙江普洛家园药业有限公司 Preparation method of 3-bromo-2-fluoronitrobenzene

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH404675A (en) * 1961-06-29 1965-12-31 Siegfried Ag Process for the preparation of new heterocyclic sulfonamido compounds
FR1469504A (en) * 1964-10-22 1967-02-17 Fisons Pest Control Ltd Insecticidal compounds
FR1477792A (en) * 1965-03-24 1967-04-21 Fisons Pest Control Ltd New benzimidazoles
GB1163711A (en) * 1966-01-13 1969-09-10 Fisons Pest Control Ltd Substituted Benzimidazoles and Biocidally-Active Compositions
GB1356244A (en) * 1970-07-29 1974-06-12 Fisons Ltd Substituted benzimidazole parasiticides

Also Published As

Publication number Publication date
NL7902802A (en) 1979-10-12
AU531086B2 (en) 1983-08-11
GR68483B (en) 1982-01-04
ES479446A1 (en) 1979-08-01
FI74461C (en) 1988-02-08
FI791083A (en) 1979-10-11
NZ190136A (en) 1982-11-23
IL57105A0 (en) 1979-07-25
FI74461B (en) 1987-10-30
DK139079A (en) 1979-10-11
DE2914084A1 (en) 1979-10-25
ZA791726B (en) 1980-05-28
AT372951B (en) 1983-12-12
SE7902911L (en) 1979-10-11
GB2018766A (en) 1979-10-24
AU4567579A (en) 1979-10-18
SE446532B (en) 1986-09-22
BE875425A (en) 1979-07-31
CA1126280A (en) 1982-06-22
JPS54138561A (en) 1979-10-27
ATA263379A (en) 1983-04-15
FR2422644B1 (en) 1982-12-17
PT69458A (en) 1979-05-01
IT7948686A0 (en) 1979-04-10
JPH0250904B2 (en) 1990-11-05
GB2018766B (en) 1982-09-22
FR2422644A1 (en) 1979-11-09
IL57105A (en) 1983-10-31

Similar Documents

Publication Publication Date Title
IT1116820B (en) MORANOLINA DERIVATIVES WITH PHARMACOLOGICAL PROPERTIES
IT1141057B (en) DEFORMYLTYLOSINE DERIVATIVES AND THEIR PREPARATION
IT1162304B (en) HETEROCYCLIC DERIVATIVES WITH ACTION ON HISTAMINE RECEPTORS AND PROCEDURE FOR THEIR PREPARATION
IT7849577A0 (en) SPIROAMINE DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY AND RELATED PRODUCTION PROCEDURE
IT8048997A0 (en) 4-AROILIMIDAZOL-2-ONS EQUIPPED WITH ANTI-HYPERTENSIVE CARDIOTONIC AND ANTITHROMBOTIC PROPERTIES AND PROCEDURE FOR THEIR PREPARATION
MX162123A (en) STRENGTHENED POLYMER COMPOSITION AND PROCEDURE TO PREPARE THE SAME
IT1123120B (en) CEFEM DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
IT1164735B (en) ADENOSINIC DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
IT1121483B (en) BENZOTIEPINIC DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
IT1164761B (en) ADMINISTRATIVE DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION
IT1171604B (en) 4-FENYL-4-OSSOBUTEN-2-OICO ACID DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL PROPERTIES AND THEIR PREPARATION PROCEDURE
IT1109545B (en) DERIVATIVES OF N-FENYL-1,3-OSSAZOLIDIN-2,4-DIONIFUNGICIDES AND PREPARATION PROCEDURE
IT1132991B (en) PROSTAGLIANDINA AND PROSTACYCLINE DERIVATIVES FOR PHARMACOLOGICAL ACTIVITIES
IT1164906B (en) INDOLIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL PROPERTIES
IT1193755B (en) BENZIMIDAZOLE AND BENZIMIDAZOLIDINA DERIVATIVES WITH DIURETIC AND ANTI-HYPERTENSIVE PROPERTIES AND PREPARATION PROCEDURE
IT1087649B (en) UREA DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITY AND COMPOSITIONS
IT1111995B (en) PROCEDURE FOR PREPARING 4,4'-BIPYRIDYL AND ITS ALCHYLIC DERIVATIVES
IT1162395B (en) AURONIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION
IT7950202A0 (en) ALFA-ARIL-ALPHA DERIVATIVES
IT1116869B (en) N-ALCHENI-MORANOLINE DERIVATIVES HAVING PHARMACOLOGICAL ACTIVITY
IT1212902B (en) ETHENDIAMMINIC AND GUANIDINIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY
IT7950523A0 (en) CARBAMOIL-PIPERAZINE DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY
IT1162310B (en) IMIDAZOLE DERIVATIVES AND PROCEDURE TO PRODUCE THEM
IT1162702B (en) DERIVATIVES OF 11-ALCANOIL-4 "-ISONITRIL-OLEANDOMYCIN
IT1174296B (en) SEMIBIOSYNTHETIC TALLISOMYCIN DERIVATIVES EQUIPPED WITH ANTI-MICROBIAL AND ANTI-TUMOR PROPERTIES AND PROCEDURE FOR THEIR PREPARATION