SE7902911L - BENSIMIDAZOLE AND BENSIMIDAZOLINDIN DERIVATIVES - Google Patents
BENSIMIDAZOLE AND BENSIMIDAZOLINDIN DERIVATIVESInfo
- Publication number
- SE7902911L SE7902911L SE7902911A SE7902911A SE7902911L SE 7902911 L SE7902911 L SE 7902911L SE 7902911 A SE7902911 A SE 7902911A SE 7902911 A SE7902911 A SE 7902911A SE 7902911 L SE7902911 L SE 7902911L
- Authority
- SE
- Sweden
- Prior art keywords
- substituted
- aryl
- heterocyclic group
- benzyl
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compounds of one of the following formulae <IMAGE> in which X represents halogen or trifluoromethyl Y1 and Y2 which may be the same or different, represent hydrogen, alkyl, acyl, aryl, substituted aryl or a heterocyclic group; R1 represents hydrogen, lower alkyl, aryl, substituted aryl, benzyl, substituted benzyl, aralkyl, a heterocyclic group or a substituted heterocyclic group; n = 0 or an integer from 1 - 4; R2 represents amino, substituted amino, guanidino, substituted guanidino, halogen, alkyl substituted alkyl, aryl, substituted aryl or a heterocyclic group and R3 represents hydrogen, lower alkyl, aryl, substituted aryl, benzyl, substituted benzyl, aralkyl a heterocyclic group, a substituted heterocyclic group or acyl, and pharmaceutically acceptable salts thereof, have diuretic and antihypertensive activity. 2-Acetimido-5-chloro-6-sulphamyl- 1H benzimidazole and 5(6)-chlorobenzimidazole- 6(5)sulphonamide and pharmaceutically acceptable salts thereof are also claimed.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89504878A | 1978-04-10 | 1978-04-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7902911L true SE7902911L (en) | 1979-10-11 |
| SE446532B SE446532B (en) | 1986-09-22 |
Family
ID=25403870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7902911A SE446532B (en) | 1978-04-10 | 1979-04-02 | BENSIMIDAZOLE AND BENSIMIDAZOLIDINE DERIVATE |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS54138561A (en) |
| AT (1) | AT372951B (en) |
| AU (1) | AU531086B2 (en) |
| BE (1) | BE875425A (en) |
| CA (1) | CA1126280A (en) |
| DE (1) | DE2914084A1 (en) |
| DK (1) | DK139079A (en) |
| ES (1) | ES479446A1 (en) |
| FI (1) | FI74461C (en) |
| FR (1) | FR2422644A1 (en) |
| GB (1) | GB2018766B (en) |
| GR (1) | GR68483B (en) |
| IL (1) | IL57105A (en) |
| IT (1) | IT1193755B (en) |
| NL (1) | NL7902802A (en) |
| NZ (1) | NZ190136A (en) |
| PT (1) | PT69458A (en) |
| SE (1) | SE446532B (en) |
| ZA (1) | ZA791726B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102070466A (en) * | 2010-12-28 | 2011-05-25 | 天津市筠凯化工科技有限公司 | Preparation method of 5-chiorine-2-nitroaniline |
| CN108558712A (en) * | 2018-06-20 | 2018-09-21 | 新乡市锦源化工有限公司 | It is a kind of using antifebrin as the method and P-aminobenzene-sulfonamide of Material synthesis high-purity P-aminobenzene-sulfonamide |
| CN110305018B (en) * | 2019-06-06 | 2022-07-15 | 浙江普洛家园药业有限公司 | Preparation method of 3-bromo-2-fluoronitrobenzene |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH404675A (en) * | 1961-06-29 | 1965-12-31 | Siegfried Ag | Process for the preparation of new heterocyclic sulfonamido compounds |
| FR1469504A (en) * | 1964-10-22 | 1967-02-17 | Fisons Pest Control Ltd | Insecticidal compounds |
| FR1477792A (en) * | 1965-03-24 | 1967-04-21 | Fisons Pest Control Ltd | New benzimidazoles |
| GB1163262A (en) * | 1966-01-13 | 1969-09-04 | Fisons Pest Control Ltd | Substituted Benzimidazoles and Biocidally Active Compositions |
| GB1356244A (en) * | 1970-07-29 | 1974-06-12 | Fisons Ltd | Substituted benzimidazole parasiticides |
-
1979
- 1979-03-26 CA CA324,146A patent/CA1126280A/en not_active Expired
- 1979-04-02 AU AU45675/79A patent/AU531086B2/en not_active Ceased
- 1979-04-02 FI FI791083A patent/FI74461C/en not_active IP Right Cessation
- 1979-04-02 SE SE7902911A patent/SE446532B/en not_active IP Right Cessation
- 1979-04-03 GR GR58771A patent/GR68483B/el unknown
- 1979-04-04 DK DK139079A patent/DK139079A/en not_active IP Right Cessation
- 1979-04-06 GB GB7912255A patent/GB2018766B/en not_active Expired
- 1979-04-07 DE DE19792914084 patent/DE2914084A1/en not_active Withdrawn
- 1979-04-09 AT AT0263379A patent/AT372951B/en not_active IP Right Cessation
- 1979-04-09 NZ NZ190136A patent/NZ190136A/en unknown
- 1979-04-09 ES ES479446A patent/ES479446A1/en not_active Expired
- 1979-04-09 PT PT69458A patent/PT69458A/en unknown
- 1979-04-09 JP JP4211979A patent/JPS54138561A/en active Granted
- 1979-04-09 BE BE0/194480A patent/BE875425A/en not_active IP Right Cessation
- 1979-04-09 FR FR7908945A patent/FR2422644A1/en active Granted
- 1979-04-10 NL NL7902802A patent/NL7902802A/en not_active Application Discontinuation
- 1979-04-10 ZA ZA791726A patent/ZA791726B/en unknown
- 1979-04-10 IT IT48686/79A patent/IT1193755B/en active
- 1979-04-22 IL IL57105A patent/IL57105A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IT1193755B (en) | 1988-08-24 |
| ES479446A1 (en) | 1979-08-01 |
| PT69458A (en) | 1979-05-01 |
| GB2018766A (en) | 1979-10-24 |
| IL57105A0 (en) | 1979-07-25 |
| JPS54138561A (en) | 1979-10-27 |
| FI74461B (en) | 1987-10-30 |
| FI74461C (en) | 1988-02-08 |
| AU4567579A (en) | 1979-10-18 |
| AT372951B (en) | 1983-12-12 |
| NZ190136A (en) | 1982-11-23 |
| JPH0250904B2 (en) | 1990-11-05 |
| GR68483B (en) | 1982-01-04 |
| SE446532B (en) | 1986-09-22 |
| GB2018766B (en) | 1982-09-22 |
| ATA263379A (en) | 1983-04-15 |
| IT7948686A0 (en) | 1979-04-10 |
| FR2422644B1 (en) | 1982-12-17 |
| NL7902802A (en) | 1979-10-12 |
| AU531086B2 (en) | 1983-08-11 |
| CA1126280A (en) | 1982-06-22 |
| DE2914084A1 (en) | 1979-10-25 |
| DK139079A (en) | 1979-10-11 |
| ZA791726B (en) | 1980-05-28 |
| FI791083A (en) | 1979-10-11 |
| FR2422644A1 (en) | 1979-11-09 |
| IL57105A (en) | 1983-10-31 |
| BE875425A (en) | 1979-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8406585D0 (en) | BENZOIC ACID DERIVATIVES | |
| NO982606D0 (en) | Naphthyl substituted benzimidazole derivatives as anticoagulants | |
| RU93035829A (en) | Aminoquinolone derivatives substituted by an aryl or heteroaromatic group and anti-HIV drugs | |
| DE69331843T2 (en) | Xanthine derivatives as antidepressants | |
| ES2097174T3 (en) | DERIVATIVES OF 2-CICLOHEXAN-1-IL AMINA. | |
| ATE18902T1 (en) | AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC USES. | |
| DK0386675T3 (en) | xanthine derivatives | |
| FI930970A (en) | IMIDAZOLDERIVAT MED BIFENYLSULFONYLUREA- ELLER BIFENYLSULPHONYLURETANSIDOKEDJA, FOERFARANDEN FOER FRAMSTAELLNING AV DESSA OCH ANVAENDNING AV DESSA | |
| ES8401032A1 (en) | 1,4-Dihydropyridines, process for their preparation and their application as pharmaceutical preparations. | |
| SE7714592L (en) | CYCLOPENTAN-1-AMINES, PROCEDURES FOR THE PREPARATION AND MEASURES CONTAINING THESE ASSOCIATIONS | |
| SE7909371L (en) | imidazole | |
| FI911980A0 (en) | N- (3-FLUOR-2-PHOSPHONYLMETHOXIPROPYL) DERIVATIVES OF THE HETEROCYCLIC PURIN- OCH PYRIMIDINE BASE, DERAS FRAMSTAELLNING OCH ANVAENDNING. | |
| ES445874A1 (en) | Indolylalkylpiperidines | |
| DE69107064D1 (en) | INDOLDER DERIVATIVES. | |
| DK484787A (en) | BIS dioxopiperazine DERIVATIVES | |
| SE7902911L (en) | BENSIMIDAZOLE AND BENSIMIDAZOLINDIN DERIVATIVES | |
| TR199802552T2 (en) | Indoline derivatives useful as 5-HT-2C Receptor antagonists. | |
| SE7811455L (en) | 2-IMINO-IMIDAZOLIDINE DERIVATIVE | |
| AU569787B2 (en) | Tetrahydrothienopyridines | |
| NO970806D0 (en) | Dihydropyridine derivatives as bradykinin antagonists | |
| ATE83481T1 (en) | FIVE-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTEN,N'-DIACYLHYDRAZINES. | |
| FI803654L (en) | NYA SUBSTITUERADE 2-PHENYLAMINOIMIDAZOLINER- (2) DERAS SYRAADDITIONSSALTER DESSA FOERENINGAR INNEHAOLLANDE CEEEMEDEL OCH DERAS FRAMSTAELLNINGSFOERFARANDE | |
| EE02942B1 (en) | Methylpiperazinoazepine derivatives, their preparation and use | |
| DK32287A (en) | 3-ACYLAMINOMETHYL-IMIDAZO (1,2-A) PYRIDINE DERIVATIVES, PROCEDURES FOR PREPARING IT, AND MEDICINAL CONTAINING SUCH DERIVATIVES | |
| SE8107680L (en) | PIPERAZINE DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7902911-2 Effective date: 19870915 Format of ref document f/p: F |