IT1100477B - Procedimento e mezzo per l'espressione microbica di polipertidi - Google Patents

Procedimento e mezzo per l'espressione microbica di polipertidi

Info

Publication number
IT1100477B
IT1100477B IT29518/78A IT2951878A IT1100477B IT 1100477 B IT1100477 B IT 1100477B IT 29518/78 A IT29518/78 A IT 29518/78A IT 2951878 A IT2951878 A IT 2951878A IT 1100477 B IT1100477 B IT 1100477B
Authority
IT
Italy
Prior art keywords
polypertids
procedure
microbial expression
microbial
expression
Prior art date
Application number
IT29518/78A
Other languages
English (en)
Italian (it)
Other versions
IT7829518A0 (it
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25306290&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1100477(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IT7829518A0 publication Critical patent/IT7829518A0/it
Application granted granted Critical
Publication of IT1100477B publication Critical patent/IT1100477B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
IT29518/78A 1977-11-08 1978-11-07 Procedimento e mezzo per l'espressione microbica di polipertidi IT1100477B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84969277A 1977-11-08 1977-11-08

Publications (2)

Publication Number Publication Date
IT7829518A0 IT7829518A0 (it) 1978-11-07
IT1100477B true IT1100477B (it) 1985-09-28

Family

ID=25306290

Family Applications (1)

Application Number Title Priority Date Filing Date
IT29518/78A IT1100477B (it) 1977-11-08 1978-11-07 Procedimento e mezzo per l'espressione microbica di polipertidi

Country Status (30)

Country Link
EP (1) EP0001929B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPS54163600A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT373279B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG38165A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1215921A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH662128A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD142561A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE2862495D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK173092B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES474852A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI783365A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2007676B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR71906B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK87184A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE47891B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL55892A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1100477B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KE (1) KE3447A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MW (1) MW3378A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY8500762A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (2) NL7811042A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO783722L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ188836A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH16937A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL210787A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT68755A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE501005C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG56884G (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (2) YU257278A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA786304B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US4171824A (en) * 1977-05-23 1979-10-23 Foster Edwin E Bicyle
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
FI792481A7 (fi) * 1978-08-11 1981-01-01 The Regents Of The Univ Of Enkaroyyttisen proteiinin synteesi mikro-organismia käyttäen.
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
ZA802992B (en) * 1979-06-01 1981-10-28 Univ California Human pre-growth hormone
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1979-09-12 1982-09-03 Univ California
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
DK170236B1 (da) * 1980-01-08 1995-07-10 Biogen Inc Rekombinante DNA-molekyler, fremgangsmåde til fremstilling af et polypeptid af IFN-alfa typen og fremgangsmåde til udvælgelse af DNA-sekvenser, der koder for polypeptider af IFN-alfa typen
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
US6455275B1 (en) 1980-02-25 2002-09-24 The Trustees Of Columbia University In The City Of New York DNA construct for producing proteinaceous materials in eucaryotic cells
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
US4769326A (en) * 1980-02-29 1988-09-06 The Regents Of The University Of California Expression linkers
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
CA1202581A (en) * 1980-03-27 1986-04-01 Saran A. Narang Adaptor molecules for dna and their application to synthesis of gene-derived products
NZ196706A (en) 1980-04-03 1988-01-08 Biogen Nv Dna sequences, recombinant dna molecules and processes for producing fibroblast interferon-like polypeptides; pharmaceutical and veterinary compositions
US6610830B1 (en) 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons
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US6692941B1 (en) 1980-08-26 2004-02-17 The Regents Of The University Of California Bovine growth hormone
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
GR81946B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1980-09-25 1984-12-12 Genentech Inc
US4506013A (en) * 1980-10-03 1985-03-19 Eli Lilly And Company Stabilizing and selecting recombinant DNA host cells
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
US4624926A (en) * 1981-01-02 1986-11-25 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
US4666836A (en) * 1981-01-02 1987-05-19 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
JPS57181098A (en) * 1981-04-30 1982-11-08 Japan Found Cancer Novel recombinant dna
JPS58996A (ja) * 1981-06-01 1983-01-06 ザ・ボ−ド・オブ・トラステイ−ズ・ミシガンステ−トユニバ−シテイ− 細菌中での牛成長ホルモン遺伝子のクロ−ン化
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
US4650761A (en) * 1981-11-27 1987-03-17 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cell
US4863855A (en) * 1982-05-14 1989-09-05 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
US4530904A (en) * 1982-09-03 1985-07-23 Eli Lilly And Company Method for conferring bacteriophage resistance to bacteria
DE3378638D1 (de) * 1982-10-25 1989-01-12 Monsanto Co Reca promoter dependent polypeptide production
ATE255162T1 (de) * 1983-01-13 2003-12-15 Max Planck Gesellschaft Transgene dicotyledone pflanzenzellen und pflanzen
US4888286A (en) * 1984-02-06 1989-12-19 Creative Biomolecules, Inc. Production of gene and protein analogs through synthetic gene design using double stranded synthetic oligonucleotides
DE3585170D1 (de) 1984-03-06 1992-02-27 Lilly Co Eli Expressionsvektoren fuer rinderwachstumshormonderivate.
GB8407044D0 (en) * 1984-03-19 1984-04-26 Fujisawa Pharmaceutical Co Producing human insulin
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
IT1198443B (it) * 1984-03-30 1988-12-21 Serono Ist Farm Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina
US4745179A (en) * 1984-04-02 1988-05-17 Fujisawa Pharmaceutical Co., Ltd. 59 Valine insulin-like growth factor I and process for production thereof
CA1213537A (en) * 1984-05-01 1986-11-04 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Polypeptide expression method
NL8401781A (nl) * 1984-06-04 1986-01-02 Rijksuniversiteit Leiden En Pr Werkwijze voor het activeren van promotoren van bacterien.
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
EP0440311A1 (en) * 1985-06-20 1991-08-07 Fujisawa Pharmaceutical Co., Ltd. A process for the production of alpha-human atrial natriuretic polypeptide
FR2594846B1 (fr) * 1986-02-21 1989-10-20 Genetica Procede de preparation de la serum albumine humaine mature
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha
US5254678A (en) * 1987-12-15 1993-10-19 Gene Shears Pty. Limited Ribozymes
DE4244915C2 (de) * 1992-08-14 1998-12-03 Widmar Prof Dr Tanner DNA-Moleküle codierend Proteine, die an der O-Glykosylierung von Proteinen beteiligt sind
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
EP2573101B1 (en) * 1996-02-09 2016-04-20 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
DE19729769A1 (de) 1997-07-11 1999-01-14 Cardiogene Gentherapeutische S Transfektionssystem, seine Herstellung und Verwendung in der somatischen Gentherapie
DE19905501B4 (de) 1999-02-10 2005-05-19 MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
DE102009001806A1 (de) 2009-03-24 2010-09-30 Evonik Degussa Gmbh Prepregs und daraus bei niedriger Temperatur hergestellte Formkörper
DE102009001793A1 (de) 2009-03-24 2010-10-07 Evonik Degussa Gmbh Prepregs und daraus hergestellte Formkörper
DE102010029355A1 (de) 2010-05-27 2011-12-01 Evonik Degussa Gmbh Verfahren zur Herstellung von lagerstabilen Polyurethan-Prepregs und daraus hergestellte Formkörper
DE102010041247A1 (de) 2010-09-23 2012-03-29 Evonik Degussa Gmbh Verfahren zur Herstellung von lagerstabilen Polyurethan-Prepregs und daraus hergestellte Formkörper aus Polyurethanzusammensetzung in Lösung
DE102011006163A1 (de) 2011-03-25 2012-09-27 Evonik Degussa Gmbh Lagerstabile Polyurethan-Prepregs und daraus hergestellte Formkörper aus Polyurethanzusammensetzung mit flüssigen Harzkomponenten
EP3330311B1 (de) 2016-12-02 2021-05-05 Evonik Operations GmbH Lagerstabile 1k-polyurethan-prepregs und daraus hergestellte formkörper aus polyurethanzusammensetzung
MX2020012454A (es) 2018-05-22 2021-06-23 Biosensor de receptor de etileno.

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GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
US4082613A (en) * 1976-04-23 1978-04-04 The Regents Of The University Of Minnesota Process for the production of insulin by genetically transformed fungal cells
DE2712615A1 (de) * 1977-03-18 1978-09-21 Max Planck Gesellschaft Verfahren zur herstellung von filamentoesen phagen als vektor fuer synthetische rekombinate
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
FI792481A7 (fi) * 1978-08-11 1981-01-01 The Regents Of The Univ Of Enkaroyyttisen proteiinin synteesi mikro-organismia käyttäen.
US4431739A (en) * 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein

Also Published As

Publication number Publication date
CA1215921A (en) 1986-12-30
DK173092B1 (da) 2000-01-10
CH662128A5 (de) 1987-09-15
ES474852A1 (es) 1979-12-01
MY8500762A (en) 1985-12-31
YU257278A (en) 1984-02-29
IL55892A (en) 1983-10-31
PL210787A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-04-21
JP2694840B2 (ja) 1997-12-24
EP0001929B1 (en) 1989-04-19
NZ188836A (en) 1982-08-17
SG56884G (en) 1985-03-08
IE782193L (en) 1979-05-08
SE501005C2 (sv) 1994-10-17
DD142561A5 (de) 1980-07-02
BG38165A3 (bg) 1985-10-15
PH16937A (en) 1984-04-24
GB2007676B (en) 1982-09-08
IT7829518A0 (it) 1978-11-07
FI783365A7 (fi) 1979-05-09
AT373279B (de) 1984-01-10
PT68755A (en) 1978-12-01
MW3378A1 (en) 1980-03-12
ZA786304B (en) 1979-10-31
EP0001929A2 (en) 1979-05-16
ATA793478A (de) 1983-05-15
YU236283A (en) 1988-08-31
NL930113I1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-10-18
HK87184A (en) 1984-11-16
DK493778A (da) 1979-05-09
GR71906B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-08-12
DE2848053A1 (de) 1979-05-10
IL55892A0 (en) 1979-01-31
EP0001929A3 (en) 1979-06-13
NL7811042A (nl) 1979-05-10
NO783722L (no) 1979-05-09
KE3447A (en) 1984-10-05
JPS54163600A (en) 1979-12-26
JPH0513630B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-02-23
SE7811461L (sv) 1979-05-09
IE47891B1 (en) 1984-07-11
JPH07284394A (ja) 1995-10-31
GB2007676A (en) 1979-05-23
DE2862495D1 (en) 1989-05-24

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ITCP Complementary protection certificate

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MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 446, 19930701; GENENTECH INC.