IS5382A - Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila - Google Patents

Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila

Info

Publication number
IS5382A
IS5382A IS5382A IS5382A IS5382A IS 5382 A IS5382 A IS 5382A IS 5382 A IS5382 A IS 5382A IS 5382 A IS5382 A IS 5382A IS 5382 A IS5382 A IS 5382A
Authority
IS
Iceland
Prior art keywords
napthyridine
carboxamide
oxo
brain
substituted
Prior art date
Application number
IS5382A
Other languages
English (en)
Icelandic (is)
Inventor
Albaugh Pamela
W. Desimone Robert
Liu Gang
Original Assignee
Neurogen Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corporation filed Critical Neurogen Corporation
Publication of IS5382A publication Critical patent/IS5382A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IS5382A 1997-08-25 2000-02-22 Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila IS5382A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91818097A 1997-08-25 1997-08-25
PCT/US1998/017513 WO1999010347A1 (en) 1997-08-25 1998-08-24 Substituted 4-oxo-napthyridine-3-carboxamides as gaba brain receptor ligands

Publications (1)

Publication Number Publication Date
IS5382A true IS5382A (is) 2000-02-22

Family

ID=25439933

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5382A IS5382A (is) 1997-08-25 2000-02-22 Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila

Country Status (24)

Country Link
EP (1) EP1007526A1 (https=)
JP (1) JP2001514181A (https=)
KR (1) KR20010023313A (https=)
CN (1) CN1268136A (https=)
AP (1) AP2000001742A0 (https=)
AU (1) AU753800B2 (https=)
BG (1) BG104192A (https=)
BR (1) BR9811362A (https=)
CA (1) CA2301599C (https=)
EG (1) EG21717A (https=)
HU (1) HUP0003258A3 (https=)
IL (1) IL134291A0 (https=)
IS (1) IS5382A (https=)
LV (1) LV12539B (https=)
NO (1) NO20000822L (https=)
NZ (1) NZ502548A (https=)
OA (1) OA11293A (https=)
PE (1) PE130999A1 (https=)
PL (1) PL338783A1 (https=)
SI (1) SI20270A (https=)
SK (1) SK2162000A3 (https=)
TW (1) TW574221B (https=)
WO (1) WO1999010347A1 (https=)
YU (1) YU10500A (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0010308A (pt) * 1999-05-06 2002-01-08 Neurogen Corp Composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento de uma doença ou distúrbio associados com o agonismo patogênico, agonismo inverso ou antagonismo do receptor de gabaa, para localizar receptores de gabaa em uma amostra de tecido, para inibir a ligação de um composto de benzodiazepina a um receptor de gabaa e para alterar a atividade da transdução de sinal dos receptores de gabaa, e, composição farmacêutica embalada
AU5289600A (en) 1999-05-25 2000-12-12 Neurogen Corporation 4h-1,4-benzothiazine-2-carboxamides and their use as gaba brain receptor ligands
US6730682B2 (en) 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
US6562822B2 (en) 2000-07-12 2003-05-13 Pharmacia & Upjohn Company Heterocyle carboxamides as antiviral agents
US6559145B2 (en) 2000-07-12 2003-05-06 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
CA2425440C (en) 2000-10-12 2010-04-13 Merck & Co., Inc. Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
JP2004517860A (ja) 2000-10-12 2004-06-17 メルク　エンド　カムパニー　インコーポレーテッド Ｈｉｖインテグラーゼ阻害薬として有用なアザ−およびポリアザ−ナフタレニルカルボキサミド類
US6919351B2 (en) 2000-10-12 2005-07-19 Merck & Co., Inc. Aza-and polyaza-naphthalenyl-carboxamides useful as HIV integrase inhibitors
US20020151591A1 (en) * 2000-10-17 2002-10-17 Anabella Villalobos Combination use of acetylcholinesterase inhibitors and GABAa inverse agonists for the treatment of cognitive disorders
WO2002069948A1 (en) * 2001-03-01 2002-09-12 Pfizer Products Inc. Use of gabaa inverse agonists in combination with nicotine receptor partial agonists, estrogen, selective estrogen modulators, or vitamin e for the treatment of cognitive disorders
AR036256A1 (es) 2001-08-17 2004-08-25 Merck & Co Inc Sal sodica de un inhibidor de integrasa del vih, procesos para su preparacion, composiciones farmaceuticas que lo contienen y su uso para la manufactura de un medicamento
EP1467970B1 (en) 2002-01-17 2007-08-22 Merck & Co., Inc. Hydroxynaphthyridinone carboxamides useful as hiv integrase inhibitors
WO2003077857A2 (en) 2002-03-15 2003-09-25 Merck & Co., Inc. N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors
WO2004106336A1 (en) * 2003-05-27 2004-12-09 Pfizer Products Inc. Process for the preparation and purification of 1,5-naphthyridine-3-carboxyamides
WO2004106334A2 (en) * 2003-05-28 2004-12-09 Pfizer Products Inc. Process for the preparation of 1,5-naphthyridine-3-carboxy amides by direct ester amidation
JP5373613B2 (ja) * 2006-10-16 2013-12-18 バイオノミクス リミテッド 新規な抗不安薬化合物
ES2610508T3 (es) * 2006-11-22 2017-04-27 Clinical Research Associates, Llc Métodos para tratar el síndrome de Down, el síndrome del cromosoma X frágil y el autismo

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204813A1 (es) * 1972-05-08 1976-03-05 Yamanouchi Pharma Co Ltd Proceso para la preparacion de derivados de ampilicina
GB1433774A (en) * 1973-02-26 1976-04-28 Allen & Hanburys Ltd Heterocyclic compounds apparatus for conveying articles
US4374138A (en) * 1981-11-13 1983-02-15 Warner-Lambert Company Antibacterial amide compounds, compositions, and methods of use
DD279887A1 (de) * 1987-07-03 1990-06-20 Inst Pharmakologische Forschun Verfahren zur herstellung von d-alpha-(4(1h)-1,5-naphthyridon-3-carboxamido)-benzylpenicillin und anderen beta-lactamantibiotika
DD279875A1 (de) * 1987-07-03 1990-06-20 Inst Pharmakologische Forschun Verfahren zur herstellung von aktivierten carbonsaeureestern
DD295360A5 (de) * 1987-07-03 1991-10-31 Akad Wissenschaften Verfahren zur Herstellung von aktivierten Carbonsäureestern
JPS6461461A (en) * 1987-09-01 1989-03-08 Otsuka Pharma Co Ltd Benzohetero ring derivative

Also Published As

Publication number Publication date
HUP0003258A2 (en) 2001-03-28
LV12539B (en) 2001-01-20
WO1999010347A1 (en) 1999-03-04
EP1007526A1 (en) 2000-06-14
HUP0003258A3 (en) 2001-05-28
AU9117398A (en) 1999-03-16
PL338783A1 (en) 2000-11-20
BR9811362A (pt) 2000-08-22
TW574221B (en) 2004-02-01
NZ502548A (en) 2002-06-28
AU753800B2 (en) 2002-10-31
CN1268136A (zh) 2000-09-27
BG104192A (en) 2001-05-31
OA11293A (en) 2002-11-19
IL134291A0 (en) 2001-04-30
CA2301599A1 (en) 1999-03-04
NO20000822D0 (no) 2000-02-18
SI20270A (sl) 2000-12-31
JP2001514181A (ja) 2001-09-11
PE130999A1 (es) 1999-12-16
CA2301599C (en) 2003-03-25
LV12539A (en) 2000-10-20
SK2162000A3 (en) 2001-03-12
KR20010023313A (ko) 2001-03-26
YU10500A (sh) 2002-10-18
EG21717A (en) 2002-02-27
NO20000822L (no) 2000-04-13
AP2000001742A0 (en) 2000-02-24

Similar Documents

Publication Publication Date Title
IS5382A (is) Setin 4-oxo-napthyridine-3-karboxamíð sem tengistGABA viðtökum í heila
NO992199L (no) Gjenget forbindelse
FI991148L (fi) Vikasietoinen teholähde
DE59806860D1 (de) Schraube mit selbstfurchendem gewinde
PT738150E (pt) Antagonistas biciclicos de fibrinogenio
DE69823749D1 (de) Vergaser mit multiplen Verwirbelungsvorrichtungen
DE69830047D1 (de) Elektrolumineszente vorrichtung
DE69908455D1 (de) Kuvertiervorrichtung
DE69919257D1 (de) Kabelbaum
DE69908446D1 (de) Programmfehlerbeseitigung
IS6290A (is) Sameinuð pirrolecarboxamíð; GABA viðtakar í heila
DE69902280D1 (de) Mit gewinde versehenes befestigungselement
DE69827655D1 (de) Drahtarmierung mit niedriger dehnung
EP0826248A4 (en) Electrochemical light-emitting devices
BR9701790A (pt) Retinóides
ATE234257T1 (de) Fadenspanner
EE200100048A (et) Antitrombootilise toimega asendatud fenüülamidiinid
DE59906674D1 (de) Beleuchtungsanordnung
DE69912593D1 (de) Sitzeinrichtung
AT500642B1 (de) Beleuchtungseinrichtung
DE59806788D1 (de) Lauflichtanlage
KR970052041U (ko) 눈내리는 효과를 갖는 장식장
KR970034875U (ko) 와이어링 고정용 클립
KR970042166U (ko) 와이어링 고정용 클립
DE69815033D1 (de) Befestigungsvorrichtung mit einstückigem Stecker