IS1380B6 - Aðferð til að framleiða díhydrópyridín efnasambönd sem hafa lyfjaverkun og eru milliefni í framleiðslu þekktra háþrýstilyfja - Google Patents

Aðferð til að framleiða díhydrópyridín efnasambönd sem hafa lyfjaverkun og eru milliefni í framleiðslu þekktra háþrýstilyfja

Info

Publication number
IS1380B6
IS1380B6 IS2808A IS2808A IS1380B6 IS 1380 B6 IS1380 B6 IS 1380B6 IS 2808 A IS2808 A IS 2808A IS 2808 A IS2808 A IS 2808A IS 1380 B6 IS1380 B6 IS 1380B6
Authority
IS
Iceland
Prior art keywords
intermediates
manufacture
preparation
pharmacologically active
hypertensive drugs
Prior art date
Application number
IS2808A
Other languages
English (en)
Icelandic (is)
Other versions
IS2808A7 (is
Inventor
Bernhard Berntsson Peder
åke Ingmar Carlsson Stig
Original Assignee
Aktiebolaget Hässle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Hässle filed Critical Aktiebolaget Hässle
Publication of IS2808A7 publication Critical patent/IS2808A7/is
Publication of IS1380B6 publication Critical patent/IS1380B6/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
IS2808A 1982-05-21 1983-05-20 Aðferð til að framleiða díhydrópyridín efnasambönd sem hafa lyfjaverkun og eru milliefni í framleiðslu þekktra háþrýstilyfja IS1380B6 (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8203177 1982-05-21

Publications (2)

Publication Number Publication Date
IS2808A7 IS2808A7 (is) 1983-11-22
IS1380B6 true IS1380B6 (is) 1989-08-28

Family

ID=20346868

Family Applications (1)

Application Number Title Priority Date Filing Date
IS2808A IS1380B6 (is) 1982-05-21 1983-05-20 Aðferð til að framleiða díhydrópyridín efnasambönd sem hafa lyfjaverkun og eru milliefni í framleiðslu þekktra háþrýstilyfja

Country Status (19)

Country Link
EP (1) EP0095450A3 (ref)
JP (1) JPS58210064A (ref)
KR (1) KR900006116B1 (ref)
AU (1) AU1464483A (ref)
CA (1) CA1242201A (ref)
DD (2) DD216454A5 (ref)
DK (1) DK223783A (ref)
ES (4) ES522573A0 (ref)
FI (1) FI79300C (ref)
GB (1) GB2120251B (ref)
GR (1) GR78849B (ref)
HU (2) HU188343B (ref)
IL (1) IL68604A0 (ref)
IS (1) IS1380B6 (ref)
MW (1) MW2083A1 (ref)
NO (1) NO162515C (ref)
NZ (1) NZ204284A (ref)
PT (1) PT76734B (ref)
ZA (1) ZA833264B (ref)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1204421B (it) * 1986-06-27 1989-03-01 Boehringer Biochemia Srl 2-(aminoalchiltio)metil-1,4-diidropiridine,un metodo per la loro preparazione e composizioni farmaceutiche che le contengono
HU199796B (en) * 1985-08-06 1990-03-28 Boehringer Biochemia Srl Process for producing 2-thiomethyl-substituted-1,4-dihydropyridines and pharmaceutical compositions comprising such compounds
IT1197012B (it) * 1986-07-29 1988-11-25 Boehringer Biochemia Srl 2-(aciltio) metil diidropiridine, un processo per la loro preparazione e composizioni farmaceutiche che le contengono
IT1213555B (it) * 1986-12-11 1989-12-20 Boehringer Biochemia Srl 2 metiltiometildiidropiridine, un processo per laloro preparazione e composizioni farmaceutiche che le contengono.
IT1213440B (it) * 1986-12-24 1989-12-20 Boehringer Biochemia Srl 2-ditioalchil-diidropiridine, un metodo per la loro preparazione e composizioni farmaceutiche chele contengono.
IT1204948B (it) * 1987-03-13 1989-03-10 Boheringer Biochemia Robin S P 2-tiometil-sostituite-piridine, metodo per la loro preparazione e composizioni farmaceutiche che le contengono.
DE3741540A1 (de) * 1987-12-08 1989-06-22 Bayer Ag Verfahren zur herstellung von unsymmetrischen dihydropyridinen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
DE2210672C3 (de) * 1972-03-06 1980-03-20 Bayer Ag, 5090 Leverkusen N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
DE2740080A1 (de) * 1977-09-06 1979-03-15 Bayer Ag 2-alkylenaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
GB2050375B (en) * 1979-05-11 1983-02-23 Fujisawa Pharmaceutical Co 4-cyanophenyl-1,4-dihydropyridine compound processes for preparation thereof and pharmaceutical composition comprising the same
SE7910521L (sv) * 1979-12-20 1981-06-21 Haessle Ab Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma

Also Published As

Publication number Publication date
GB2120251B (en) 1985-11-27
PT76734B (en) 1986-03-27
DK223783D0 (da) 1983-05-19
EP0095450A2 (en) 1983-11-30
ES542185A0 (es) 1985-12-16
KR900006116B1 (ko) 1990-08-22
ES542186A0 (es) 1985-12-16
NO162515B (no) 1989-10-02
ES542187A0 (es) 1985-12-16
MW2083A1 (en) 1985-06-12
ES8603416A1 (es) 1985-12-16
KR840004724A (ko) 1984-10-24
JPS58210064A (ja) 1983-12-07
NO831807L (no) 1983-11-22
ZA833264B (en) 1984-06-27
AU1464483A (en) 1983-11-24
HU188343B (en) 1986-04-28
FI79300B (fi) 1989-08-31
ES8600242A1 (es) 1985-10-01
NO162515C (no) 1990-01-10
ES8603415A1 (es) 1985-12-16
GR78849B (ref) 1984-10-02
IL68604A0 (en) 1983-09-30
FI79300C (fi) 1989-12-11
DK223783A (da) 1983-11-22
DD216454A5 (de) 1984-12-12
GB8314021D0 (en) 1983-06-29
FI831779A0 (fi) 1983-05-19
PT76734A (en) 1983-06-01
ES8603417A1 (es) 1985-12-16
FI831779L (fi) 1983-11-22
HU193785B (en) 1987-11-30
GB2120251A (en) 1983-11-30
NZ204284A (en) 1985-11-08
ES522573A0 (es) 1985-10-01
CA1242201A (en) 1988-09-20
IS2808A7 (is) 1983-11-22
EP0095450A3 (en) 1984-09-05
DD211554A5 (de) 1984-07-18

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