IN2014DN06768A - - Google Patents
Info
- Publication number
- IN2014DN06768A IN2014DN06768A IN6768DEN2014A IN2014DN06768A IN 2014DN06768 A IN2014DN06768 A IN 2014DN06768A IN 6768DEN2014 A IN6768DEN2014 A IN 6768DEN2014A IN 2014DN06768 A IN2014DN06768 A IN 2014DN06768A
- Authority
- IN
- India
- Prior art keywords
- protected
- protected oligonucleotide
- elongation
- discovered
- conducted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012033429 | 2012-02-17 | ||
| JP2012254718 | 2012-11-20 | ||
| PCT/JP2013/053769 WO2013122236A1 (ja) | 2012-02-17 | 2013-02-15 | 塩基部保護オリゴヌクレオチド |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN06768A true IN2014DN06768A (de) | 2015-05-22 |
Family
ID=48984345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN6768DEN2014 IN2014DN06768A (de) | 2012-02-17 | 2013-02-15 |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP3296306B1 (de) |
| JP (1) | JP6237237B2 (de) |
| CN (2) | CN104114569B (de) |
| IN (1) | IN2014DN06768A (de) |
| WO (1) | WO2013122236A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5979139B2 (ja) | 2011-05-17 | 2016-08-24 | 味の素株式会社 | オリゴヌクレオチドの製造方法 |
| US9284344B2 (en) | 2012-05-30 | 2016-03-15 | Hokkaido System Science Co., Ltd. | Oligonucleotide synthesis method using highly dispersible liquid-phase support |
| JP6218333B2 (ja) * | 2012-11-14 | 2017-10-25 | 武田薬品工業株式会社 | 核酸の液相合成方法 |
| CN106795186B (zh) | 2014-10-14 | 2021-03-02 | 味之素株式会社 | 吗啉代寡核苷酸的制备方法 |
| JP6950529B2 (ja) * | 2015-11-17 | 2021-10-13 | 日産化学株式会社 | オリゴヌクレオチドの製造方法 |
| CN116063365A (zh) | 2015-12-16 | 2023-05-05 | 味之素株式会社 | 寡核苷酸的制备方法以及核苷、核苷酸或寡核苷酸 |
| WO2017111137A1 (ja) * | 2015-12-22 | 2017-06-29 | 味の素株式会社 | オリゴヌクレオチドの製造方法 |
| CN107556355B (zh) * | 2016-06-30 | 2021-10-22 | 上海兆维科技发展有限公司 | 一种核苷双亚磷酰胺及其制备方法 |
| JP7306263B2 (ja) * | 2017-05-02 | 2023-07-11 | 日産化学株式会社 | オリゴヌクレオチドの製造方法 |
| JP7140111B2 (ja) * | 2017-05-16 | 2022-09-21 | 日産化学株式会社 | オリゴヌクレオチドの製造方法 |
| JP2021516673A (ja) * | 2018-03-14 | 2021-07-08 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｌｎａ−ジカルボン酸誘導体およびその調製のための方法 |
| KR20210008055A (ko) | 2018-05-10 | 2021-01-20 | 니뽄 신야쿠 가부시키가이샤 | 올리고 핵산 화합물의 제조 방법 |
| CN113423715A (zh) | 2019-02-15 | 2021-09-21 | 味之素株式会社 | 寡核苷酸的制造方法 |
| EP3950698A4 (de) * | 2019-03-28 | 2023-01-25 | Ajinomoto Co., Inc. | Verfahren zur herstellung eines oligonukleotids mit phosphorothioatstelle |
| CA3139545A1 (en) * | 2019-05-08 | 2020-11-12 | Biogen Ma Inc. | Convergent liquid phase syntheses of oligonucleotides |
| JPWO2021045141A1 (de) * | 2019-09-04 | 2021-03-11 | ||
| KR20220098217A (ko) | 2019-11-13 | 2022-07-11 | 니뽄 신야쿠 가부시키가이샤 | 올리고 핵산 화합물의 제조 방법 |
| CN114981280A (zh) | 2019-11-13 | 2022-08-30 | 日本新药株式会社 | 寡核苷酸化合物的制造方法 |
| CN111039977B (zh) * | 2019-12-31 | 2022-11-08 | 广州同隽医药科技有限公司 | 一种亚磷酰化试剂及其在寡核苷酸合成中的应用 |
| JP2023551647A (ja) * | 2020-11-11 | 2023-12-12 | バイオジェン・エムエイ・インコーポレイテッド | オリゴヌクレオチド、試薬、及びその調製 |
| EP4332111A1 (de) | 2021-04-28 | 2024-03-06 | Nippon Shinyaku Co., Ltd. | Verfahren zur herstellung einer oligonukleinsäureverbindung |
| KR20240129006A (ko) | 2021-12-27 | 2024-08-27 | 니뽄 신야쿠 가부시키가이샤 | 올리고 핵산 화합물의 제조 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61112093A (ja) * | 1984-11-05 | 1986-05-30 | Wakunaga Seiyaku Kk | ヌクレオチド誘導体 |
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| US5459255A (en) * | 1990-01-11 | 1995-10-17 | Isis Pharmaceuticals, Inc. | N-2 substituted purines |
| US20040082774A1 (en) * | 1999-03-16 | 2004-04-29 | Guzaev Andrei P. | Novel phosphate and thiophosphate protecting groups |
| JP4945129B2 (ja) * | 2004-01-27 | 2012-06-06 | 株式会社キラルジェン | フルオラス担体およびそれを用いたオリゴヌクレオチド誘導体の製造方法 |
| JP5750209B2 (ja) * | 2007-03-16 | 2015-07-15 | アプタ バイオサイエンス リミテッド | 機能性分子、機能性分子合成用アミダイド、及び標的物質解析方法 |
| JP5548852B2 (ja) * | 2009-05-29 | 2014-07-16 | 国立大学法人東京農工大学 | 疎水性基結合ヌクレオシド、疎水性基結合ヌクレオシド溶液、及び疎水性基結合オリゴヌクレオチド合成方法 |
| CN102191233B (zh) * | 2010-03-04 | 2014-06-04 | 中国人民解放军军事医学科学院毒物药物研究所 | 新颖的10-23脱氧核酶类似物及其用途 |
| JP2012033429A (ja) | 2010-08-02 | 2012-02-16 | Polymatech Co Ltd | 操作スイッチ |
| JP5979139B2 (ja) * | 2011-05-17 | 2016-08-24 | 味の素株式会社 | オリゴヌクレオチドの製造方法 |
| JP5760722B2 (ja) | 2011-06-09 | 2015-08-12 | 横浜ゴム株式会社 | 空気入りタイヤおよびその製造方法 |
| US9284344B2 (en) * | 2012-05-30 | 2016-03-15 | Hokkaido System Science Co., Ltd. | Oligonucleotide synthesis method using highly dispersible liquid-phase support |
-
2013
- 2013-02-15 EP EP17194621.3A patent/EP3296306B1/de active Active
- 2013-02-15 CN CN201380009595.0A patent/CN104114569B/zh active Active
- 2013-02-15 JP JP2013558763A patent/JP6237237B2/ja active Active
- 2013-02-15 WO PCT/JP2013/053769 patent/WO2013122236A1/ja active Application Filing
- 2013-02-15 EP EP13749023.1A patent/EP2816053B1/de active Active
- 2013-02-15 IN IN6768DEN2014 patent/IN2014DN06768A/en unknown
- 2013-02-15 CN CN201610883841.0A patent/CN106977567B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2013122236A1 (ja) | 2015-05-18 |
| EP2816053B1 (de) | 2021-03-24 |
| CN104114569B (zh) | 2017-04-26 |
| CN106977567B (zh) | 2021-02-02 |
| EP2816053A1 (de) | 2014-12-24 |
| EP2816053A4 (de) | 2015-07-01 |
| JP6237237B2 (ja) | 2017-11-29 |
| CN106977567A (zh) | 2017-07-25 |
| CN104114569A (zh) | 2014-10-22 |
| WO2013122236A1 (ja) | 2013-08-22 |
| EP3296306A1 (de) | 2018-03-21 |
| EP3296306B1 (de) | 2022-11-09 |
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