IN2014CN04126A - - Google Patents
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- Publication number
- IN2014CN04126A IN2014CN04126A IN4126CHN2014A IN2014CN04126A IN 2014CN04126 A IN2014CN04126 A IN 2014CN04126A IN 4126CHN2014 A IN4126CHN2014 A IN 4126CHN2014A IN 2014CN04126 A IN2014CN04126 A IN 2014CN04126A
- Authority
- IN
- India
- Prior art keywords
- attachment
- group
- point
- compounds
- alkyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000006177 alkyl benzyl group Chemical group 0.000 abstract 1
- 125000005189 alkyl hydroxy group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2011054968 | 2011-11-08 | ||
| PCT/IB2012/056236 WO2013068948A1 (en) | 2011-11-08 | 2012-11-07 | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04126A true IN2014CN04126A (enExample) | 2015-07-10 |
Family
ID=47258051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4126CHN2014 IN2014CN04126A (enExample) | 2011-11-08 | 2012-11-07 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9079922B2 (enExample) |
| EP (1) | EP2776431B1 (enExample) |
| JP (1) | JP6030146B2 (enExample) |
| KR (1) | KR20140096337A (enExample) |
| AR (1) | AR088691A1 (enExample) |
| AU (1) | AU2012335207B2 (enExample) |
| BR (1) | BR112014011064A8 (enExample) |
| CA (1) | CA2854264A1 (enExample) |
| CL (1) | CL2014001154A1 (enExample) |
| ES (1) | ES2581056T3 (enExample) |
| HK (1) | HK1202288A1 (enExample) |
| IL (1) | IL232463A0 (enExample) |
| IN (1) | IN2014CN04126A (enExample) |
| MX (1) | MX344529B (enExample) |
| PH (1) | PH12014500831A1 (enExample) |
| PL (1) | PL2776431T3 (enExample) |
| RU (1) | RU2616609C2 (enExample) |
| SG (1) | SG11201401710PA (enExample) |
| TW (1) | TWI594996B (enExample) |
| WO (1) | WO2013068948A1 (enExample) |
| ZA (1) | ZA201404176B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4833385B1 (ja) | 2008-10-07 | 2011-12-07 | アクテリオン ファーマシューティカルズ リミテッド | 三環式オキサゾリジノン抗生物質化合物 |
| MA38588B1 (fr) | 2013-04-16 | 2018-04-30 | Idorsia Pharmaceuticals Ltd | Dérivés bi-aromatiques antibactériens |
| AR096135A1 (es) | 2013-05-02 | 2015-12-09 | Actelion Pharmaceuticals Ltd | Derivados de la quinolona |
| AR102256A1 (es) | 2014-10-15 | 2017-02-15 | Actelion Pharmaceuticals Ltd | Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi |
| MA41169A (fr) | 2014-12-17 | 2017-10-24 | Acraf | Composés antibactériens à large spectre d'activité |
| MA41168A (fr) | 2014-12-17 | 2017-10-24 | Acraf | Nouveaux composés antibactériens |
| CA3012569A1 (en) * | 2016-02-08 | 2017-08-17 | Redx Pharma Plc | Antibacterial compounds |
| GB201602235D0 (en) * | 2016-02-08 | 2016-03-23 | Redx Pharma Plc | Antibacterial compounds |
| EP3413976A1 (en) * | 2016-02-08 | 2018-12-19 | Redx Pharma PLC | Heterocyclic compounds, in particular 2-oxo-4,4,5,5,6,6,7,7-octahydrobenzoxazole derivatives, and their use as antibacterial compounds |
| EP3468975B1 (en) | 2016-06-08 | 2020-04-01 | Aziende Chimiche Riunite Angelini Francesco A.C.R. | New antibacterial compounds |
| TW201833120A (zh) | 2017-02-17 | 2018-09-16 | 瑞士商愛杜西亞製藥有限公司 | 芳基噁唑啶酮抗生素化合物 |
| US10912780B2 (en) | 2017-06-08 | 2021-02-09 | Bugworks Research, Inc. | Heterocyclic compounds useful as anti-bacterial agents and method for production thereof |
| CN111527093B (zh) * | 2017-11-29 | 2023-06-09 | 巴格沃克斯研究有限公司 | 抗菌杂环化合物及其合成 |
| JP2024529132A (ja) * | 2021-08-13 | 2024-08-01 | バグワークス・リサーチ・インディア・ピーヴィーティー・リミテッド | 抗生物質ピラジノチアジン誘導体及びその調製方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149104A (en) | 1961-01-03 | 1964-09-15 | Sterling Drug Inc | 4-hydroxy-7-styryl-1, 8-naphthyridine-3-carboxylic acids and esters |
| DE2362553A1 (de) | 1972-12-18 | 1974-06-20 | Dainippon Pharmaceutical Co | Neue piperazinderivate |
| SE444566B (sv) | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav |
| GB1598915A (en) | 1977-09-20 | 1981-09-23 | Bellon Labor Sa Roger | 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them |
| CS274601B2 (en) | 1983-07-27 | 1991-09-15 | Dainippon Pharmaceutical Co | Method of 1,8-naphthyridine derivative production |
| JPS62205060A (ja) | 1986-03-04 | 1987-09-09 | Kyorin Pharmaceut Co Ltd | ８位置換キノロンカルボン酸誘導体 |
| DK164287A (da) | 1986-03-31 | 1987-10-01 | Sankyo Co | Quinolin-3-carboxylsyrederivater og fremgangsmaade til fremstilling deraf og deres anvendelse |
| JP2631854B2 (ja) | 1987-12-23 | 1997-07-16 | 藤本製薬株式会社 | 新規な１，８−ナフチリジン誘導体 |
| DE4301246A1 (de) | 1993-01-19 | 1994-07-21 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäurederivate |
| AU2003244235A1 (en) | 2002-06-28 | 2004-01-19 | Kaneka Corporation | Process for preparation of optically active 1-substituted amino-2,3-epoxypropanes, intermediates for the synthesis thereof and process for preparation of the intermediates |
| MXPA05011654A (es) * | 2003-04-30 | 2005-12-15 | Morphochem Ag Komb Chemie | Uso de antibioticos hibridos de oxazolidinona-quinolina para el tratamiento del antrax y de otras infecciones. |
| ES2310299T5 (es) * | 2003-12-18 | 2014-02-10 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Antibióticos híbridos a base de oxazolidinona-quinolona |
| BRPI0514381A (pt) | 2004-07-30 | 2008-06-10 | Palumed Sa | compostos hìbridos de aminoquinolina-antibiótico, composições farmacêuticas, método de preparação e uso destes |
| DE602005015341D1 (de) | 2004-09-01 | 2009-08-20 | Ubitrak Inc | System zum identifizieren und zählen von spieljetons |
| US20090156577A1 (en) | 2004-09-09 | 2009-06-18 | Benjamin Davis | 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones |
| US7709496B2 (en) | 2006-04-06 | 2010-05-04 | Glaxo Group Limited | Antibacterial agents |
| CL2007003232A1 (es) * | 2006-11-10 | 2008-06-27 | Actelion Pharmaceuticals Ltd | Compuestos derivados de 5-hidroximetil oxazolidin-2-ona; composicion farmaceutica que contiene a dichos compuestos; y su uso para tratar y prevenir infecciones bacterianas. |
| CL2008001002A1 (es) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| CL2008001003A1 (es) * | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| JP5323088B2 (ja) * | 2007-12-18 | 2013-10-23 | アクテリオン ファーマシューティカルズ リミテッド | ５−アミノシクリルメチル−オキサゾリジン−２−オン誘導体 |
| CA2713187C (en) * | 2008-02-22 | 2016-06-07 | Actelion Pharmaceuticals Ltd | Oxazolidinone derivatives |
| JP4833385B1 (ja) | 2008-10-07 | 2011-12-07 | アクテリオン ファーマシューティカルズ リミテッド | 三環式オキサゾリジノン抗生物質化合物 |
| ES2395491T3 (es) * | 2008-10-10 | 2013-02-13 | Actelion Pharmaceuticals Ltd. | 2-Benzotiofenil y 2-naftil-oxazolidinonas y sus análogos azaisósteros como agentes antibacterianos |
| JP5490809B2 (ja) * | 2008-10-10 | 2014-05-14 | アクテリオン ファーマシューティカルズ リミテッド | オキサゾリジニル抗生物質 |
| TW201121965A (en) | 2009-09-28 | 2011-07-01 | Lg Life Sciences Ltd | Use of a quinolone derivative containing 7-(4-aminomethyl-3-oxime)pyrrolidine group that is capable of inducing granulocyte colony stimulating factor for treatment of neutropenia and recovery of hematopoiesis |
| CN101792443A (zh) | 2010-03-09 | 2010-08-04 | 北京欧凯纳斯科技有限公司 | 氟代喹诺酮衍生物及其制备方法和用途 |
-
2012
- 2012-11-07 IN IN4126CHN2014 patent/IN2014CN04126A/en unknown
- 2012-11-07 PL PL12791863.9T patent/PL2776431T3/pl unknown
- 2012-11-07 BR BR112014011064A patent/BR112014011064A8/pt not_active Application Discontinuation
- 2012-11-07 SG SG11201401710PA patent/SG11201401710PA/en unknown
- 2012-11-07 MX MX2014005637A patent/MX344529B/es active IP Right Grant
- 2012-11-07 US US14/356,896 patent/US9079922B2/en not_active Expired - Fee Related
- 2012-11-07 HK HK15102622.5A patent/HK1202288A1/xx unknown
- 2012-11-07 KR KR1020147014957A patent/KR20140096337A/ko not_active Abandoned
- 2012-11-07 JP JP2014540612A patent/JP6030146B2/ja not_active Expired - Fee Related
- 2012-11-07 WO PCT/IB2012/056236 patent/WO2013068948A1/en not_active Ceased
- 2012-11-07 AU AU2012335207A patent/AU2012335207B2/en not_active Ceased
- 2012-11-07 CA CA2854264A patent/CA2854264A1/en not_active Abandoned
- 2012-11-07 TW TW101141423A patent/TWI594996B/zh not_active IP Right Cessation
- 2012-11-07 PH PH1/2014/500831A patent/PH12014500831A1/en unknown
- 2012-11-07 AR ARP120104192A patent/AR088691A1/es unknown
- 2012-11-07 ES ES12791863.9T patent/ES2581056T3/es active Active
- 2012-11-07 EP EP12791863.9A patent/EP2776431B1/en not_active Not-in-force
- 2012-11-07 RU RU2014123109A patent/RU2616609C2/ru not_active IP Right Cessation
-
2014
- 2014-04-30 CL CL2014001154A patent/CL2014001154A1/es unknown
- 2014-05-05 IL IL232463A patent/IL232463A0/en unknown
- 2014-06-06 ZA ZA2014/04176A patent/ZA201404176B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014123109A (ru) | 2015-12-20 |
| US9079922B2 (en) | 2015-07-14 |
| HK1202288A1 (en) | 2015-09-25 |
| ES2581056T3 (es) | 2016-08-31 |
| TW201326166A (zh) | 2013-07-01 |
| BR112014011064A8 (pt) | 2017-12-26 |
| CA2854264A1 (en) | 2013-05-16 |
| MX344529B (es) | 2016-12-19 |
| EP2776431B1 (en) | 2016-05-04 |
| AR088691A1 (es) | 2014-06-25 |
| KR20140096337A (ko) | 2014-08-05 |
| BR112014011064A2 (pt) | 2017-06-13 |
| PL2776431T3 (pl) | 2016-11-30 |
| WO2013068948A1 (en) | 2013-05-16 |
| JP2014532754A (ja) | 2014-12-08 |
| RU2616609C2 (ru) | 2017-04-18 |
| AU2012335207B2 (en) | 2017-05-25 |
| PH12014500831A1 (en) | 2019-08-07 |
| TWI594996B (zh) | 2017-08-11 |
| AU2012335207A1 (en) | 2014-07-03 |
| EP2776431A1 (en) | 2014-09-17 |
| SG11201401710PA (en) | 2014-09-26 |
| CN103917539A (zh) | 2014-07-09 |
| ZA201404176B (en) | 2016-05-25 |
| IL232463A0 (en) | 2014-06-30 |
| JP6030146B2 (ja) | 2016-11-24 |
| MX2014005637A (es) | 2014-06-23 |
| CL2014001154A1 (es) | 2014-09-12 |
| US20150051188A1 (en) | 2015-02-19 |
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