IN2014CN04002A - - Google Patents

Info

Publication number
IN2014CN04002A
IN2014CN04002A IN4002CHN2014A IN2014CN04002A IN 2014CN04002 A IN2014CN04002 A IN 2014CN04002A IN 4002CHN2014 A IN4002CHN2014 A IN 4002CHN2014A IN 2014CN04002 A IN2014CN04002 A IN 2014CN04002A
Authority
IN
India
Prior art keywords
polymeric
coryneform bacteria
protein secretion
production capabilities
proteins
Prior art date
Application number
Other languages
English (en)
Inventor
Yoshihiko Matsuda
Haruki Beppu
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of IN2014CN04002A publication Critical patent/IN2014CN04002A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
IN4002CHN2014 2011-11-02 2012-11-01 IN2014CN04002A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2011240745 2011-11-02
PCT/JP2012/078285 WO2013065772A1 (fr) 2011-11-02 2012-11-01 Procédé de sécrétion et de production de protéines

Publications (1)

Publication Number Publication Date
IN2014CN04002A true IN2014CN04002A (fr) 2015-10-23

Family

ID=48192110

Family Applications (1)

Application Number Title Priority Date Filing Date
IN4002CHN2014 IN2014CN04002A (fr) 2011-11-02 2012-11-01

Country Status (7)

Country Link
US (1) US9404138B2 (fr)
EP (1) EP2774982B1 (fr)
JP (1) JP6136930B2 (fr)
CN (1) CN103946372B (fr)
AU (1) AU2012333515B2 (fr)
IN (1) IN2014CN04002A (fr)
WO (1) WO2013065772A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014CN04039A (fr) 2011-11-02 2015-10-23 Ajinomoto Kk
IN2014CN04002A (fr) 2011-11-02 2015-10-23 Ajinomoto Kk
WO2015060391A1 (fr) 2013-10-23 2015-04-30 味の素株式会社 Procédé de production d'une substance cible
EP3101129B1 (fr) 2014-01-31 2020-10-28 Kaneka Corporation Micro-organisme ayant une expression ajustée du gène d'énoyl-coa hydratase r-spécifique, et procédé de fabrication de copolymère de polyhydroxyalcanoate utilisant celui-ci
CN107532163A (zh) 2015-04-24 2018-01-02 味之素株式会社 蛋白质的分泌生产方法
EP3530747A4 (fr) * 2016-10-21 2020-07-22 Ajinomoto Co., Inc. Procédé de production sécrétoire de protéines
KR102335301B1 (ko) 2016-10-21 2021-12-06 아지노모토 가부시키가이샤 단백질의 분비 생산법
CN106754533B (zh) * 2016-12-30 2020-06-30 四川大学 一种具有分解蛋白质性能的棒状杆菌、生产方法及其应用
BR112019018859A2 (pt) 2017-03-28 2020-04-14 Ajinomoto Kk método para produzir rna objetivo
WO2019078095A1 (fr) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. Procédé de production d'une protéine ayant une activité peptidylglycine monooxygénase alpha-hydroxylante
JP7367667B2 (ja) 2018-02-20 2023-10-24 味の素株式会社 Ｒｎａサイレンシングを誘導する方法
KR20210002575A (ko) 2018-04-20 2021-01-08 아지노모토 가부시키가이샤 단백질의 분비 생산법
EP3861109A1 (fr) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Procédé de production d'une substance cible par fermentation bactérienne
KR20210082212A (ko) * 2018-10-25 2021-07-02 아지노모토 가부시키가이샤 단백질의 분비 생산법
AU2022306337A1 (en) 2021-07-07 2024-02-01 Ajinomoto Co., Inc. Method for secretory production of unnatural-amino-acid-containing protein
CN116200416B (zh) * 2023-02-15 2024-03-12 北京康乐卫士生物技术股份有限公司 一种基于Tac启动子的质粒表达载体构建及其用途

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57134500A (en) 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS5835197A (ja) 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
JPS5867679A (ja) 1981-09-30 1983-04-22 アメリカン・サイアナミド・カンパニ− イソシアン酸を三量化してシアヌル酸をつくる方法
JPS5877895A (ja) 1981-11-02 1983-05-11 Ajinomoto Co Inc プラスミドｐｈｍ１５１９
JPS58192900A (ja) 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
US4965197A (en) 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system
JPH01191686A (ja) 1988-01-26 1989-08-01 Mitsubishi Petrochem Co Ltd 複合プラスミド
FR2627508B1 (fr) 1988-02-22 1990-10-05 Eurolysine Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede
JP2678995B2 (ja) 1988-09-08 1997-11-19 三菱化学株式会社 トリプトフアンシンターゼの製造法
US5185262A (en) 1988-07-27 1993-02-09 Mitsubishi Petrochemical Co., Ltd. DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism
JPH02207791A (ja) 1989-02-07 1990-08-17 Ajinomoto Co Inc 微生物の形質転換法
JP2973446B2 (ja) 1990-01-11 1999-11-08 三菱化学株式会社 新規プラスミドベクター
JPH07108228B2 (ja) 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド
WO1993003158A1 (fr) 1991-07-30 1993-02-18 Orsan Systeme d'expression et de secretion de proteines utilisables en particulier chez les corynebacteries
AU4431196A (en) 1995-01-23 1996-08-14 Novo Nordisk A/S Dna integration by transposition
JPH0970291A (ja) 1995-06-30 1997-03-18 Ajinomoto Co Inc 人工トランスポゾンを用いた遺伝子増幅方法
JP4035855B2 (ja) 1996-06-05 2008-01-23 味の素株式会社 Ｌ−リジンの製造法
JP3711658B2 (ja) 1996-10-07 2005-11-02 味の素株式会社 コリネバクテリウム・アンモニアゲネス由来の新規な細胞表層蛋白質
JP4168463B2 (ja) 1996-12-05 2008-10-22 味の素株式会社 Ｌ−リジンの製造法
JPH11169182A (ja) 1997-12-10 1999-06-29 Mitsubishi Chemical Corp コリネ型細菌内で蛋白質を効率よく培地中へ分泌させる変異型分泌装置遺伝子
CN101200742A (zh) * 1998-03-06 2008-06-18 味之素株式会社 编码青霉素结合蛋白的基因和生产l-谷氨酸的方法
DE69941594D1 (de) 1998-09-25 2009-12-10 Ajinomoto Kk Coryneforme bakterien zur herstellung von l-glu
JP2000262288A (ja) 1999-03-16 2000-09-26 Ajinomoto Co Inc コリネ型細菌の温度感受性プラスミド
US20050244935A1 (en) * 1999-06-25 2005-11-03 Basf Ag Corynebacterium glutamicum genes encoding proteins involved in membrane synthesis and membrane transport
DE60042552D1 (de) 1999-08-02 2009-08-27 Archer Daniels Midland Co Metabolische manipulation der produktion von aminosäuren
AU7449400A (en) 1999-09-30 2001-04-30 Ajinomoto Co., Inc. Process for producing transglutaminase
DK1253195T3 (da) 2000-01-21 2009-01-12 Ajinomoto Kk Fremgangsmåde til fremstilling af L-lysin
BR0208136B1 (pt) 2001-03-30 2014-10-21 Ajinomoto Kk Método para produzir uma proteína heteróloga
BR0211723A (pt) 2001-08-06 2004-09-21 Degussa Bactérias corineformes que produzem compostos quìmicos i
AU2003268693A1 (en) 2002-09-30 2004-04-19 Ajinomoto Co., Inc. Method of producing stable isotope-labeled protein
KR20050106502A (ko) 2003-03-07 2005-11-09 아지노모토 가부시키가이샤 미생물 트랜스글루타미나제의 제조방법
RU2337140C2 (ru) 2003-07-29 2008-10-27 Адзиномото Ко., Инк. Способ продуцирования l-лизина или l-треонина с помощью бактерий escherichia, имеющих аттенуированную активность малеинового фермента
WO2005090564A1 (fr) * 2004-03-19 2005-09-29 Genomidea Inc. Gene activant le developpement de cellules endotheliales vasculaires
JP4760711B2 (ja) 2004-03-31 2011-08-31 味の素株式会社 バチルス属又はエシェリヒア属に属する細菌を使用した発酵によるプリンヌクレオシド及びヌクレオチドの製造方法
CN100554431C (zh) * 2004-04-20 2009-10-28 味之素株式会社 生产蛋白质的方法
JP4730302B2 (ja) 2004-04-20 2011-07-20 味の素株式会社 タンパク質の製造法
CN1989238B (zh) 2004-05-20 2010-05-26 味之素株式会社 生产琥珀酸的细菌和生产琥珀酸的方法
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
CA2598792A1 (fr) * 2005-03-02 2006-09-08 Metanomics Gmbh Procede de production de produits chimiques fins
US7723097B2 (en) 2005-03-11 2010-05-25 Archer-Daniels-Midland Company Escherichia coli strains that over-produce L-threonine and processes for their production
RU2365622C2 (ru) 2006-12-22 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus
RU2355759C1 (ru) 2007-08-14 2009-05-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ АРОМАТИЧЕСКОЙ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН ydiB, СПОСОБ ПОЛУЧЕНИЯ СЛОЖНОГО ЭФИРА НИЗШИХ АЛКИЛОВ АЛЬФА-L-АСПАРТИЛ-L-ФЕНИЛАЛАНИНА
JP5445453B2 (ja) 2008-07-09 2014-03-19 味の素株式会社 アミノヒドロキシ安息香酸類の製造方法
IN2014CN04002A (fr) 2011-11-02 2015-10-23 Ajinomoto Kk
IN2014CN04039A (fr) 2011-11-02 2015-10-23 Ajinomoto Kk

Also Published As

Publication number Publication date
EP2774982A1 (fr) 2014-09-10
US20140234901A1 (en) 2014-08-21
AU2012333515A1 (en) 2014-06-12
EP2774982B1 (fr) 2017-06-21
AU2012333515B2 (en) 2015-07-16
WO2013065772A1 (fr) 2013-05-10
JP6136930B2 (ja) 2017-05-31
EP2774982A4 (fr) 2015-03-18
JPWO2013065772A1 (ja) 2015-04-02
US9404138B2 (en) 2016-08-02
CN103946372A (zh) 2014-07-23
CN103946372B (zh) 2016-06-08

Similar Documents

Publication Publication Date Title
IN2014CN04002A (fr)
MX2018002705A (es) Cepas de levadura para la expresion y secrecion de proteinas heterologas a altas temperaturas.
IN2014CN04039A (fr)
MX2015016947A (es) Metodos para producir derivados de acido graso omega-hidroxilados.
MY165893A (en) Biological methods for preparing a fatty dicarboxylic acid
WO2016171224A9 (fr) Procédé de production d'une protéine par sécrétion
MY161726A (en) Biological methods for preparing adipic acid
MY157111A (en) Recombinant microorganisms and methods of production thereof
MX2019004568A (es) Produccion mejorada de derivados de acidos grasos.
IN2014CN04586A (fr)
MX351565B (es) Colageno 7 y metodos relacionados.
PL2917359T3 (pl) Sposób enzymatycznej hydrolizy materiału lignocelulozowego z zastosowaniem tlenu
EP2735616A4 (fr) Procédé de production pour des peptides dérivés de caséine par fermentation d'acide lactique
MY175182A (en) Strain having enhanced l-valine productivity and l-valine production method using the same
MX368142B (es) Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab.
EP2494053A4 (fr) Procédés de production de protéines recombinantes présentant de meilleurs rendements de sécrétions
WO2014100504A3 (fr) Procédés biologiques de préparation d'un acide gras dicarboxylique
EP2548968A4 (fr) Procédé de fabrication d'astaxanthine par fermentation
EA201270095A1 (ru) Способ получения ферментированного молочного продукта
HUP1100510A2 (en) Production of biogas from protein-rich material
EA201270085A1 (ru) Способ получения ферментированного молочного продукта
MX2020001357A (es) Produccion microbiana de aminas grasas.
MX2016002651A (es) Microorganismo modificado para la produccion mejorada de alanina.
UA108343C2 (uk) Спосіб одержання сквалену за допомогою дріжджів
EP2801612A4 (fr) Microorganisme recombinant produisant de l'acide quinolinique et procédé de production d'acide quinolinique l'utilisant