IN2013CN00757A - - Google Patents
Info
- Publication number
- IN2013CN00757A IN2013CN00757A IN757CHN2013A IN2013CN00757A IN 2013CN00757 A IN2013CN00757 A IN 2013CN00757A IN 757CHN2013 A IN757CHN2013 A IN 757CHN2013A IN 2013CN00757 A IN2013CN00757 A IN 2013CN00757A
- Authority
- IN
- India
- Prior art keywords
- seq
- vinylcyclopropane
- sequence represented
- protein
- amino acid
- Prior art date
Links
- 102000004157 Hydrolases Human genes 0.000 abstract 2
- 108090000604 Hydrolases Proteins 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- ZSOAZJCWMJEXKS-UHFFFAOYSA-N 1-ethenyl-2,3-diethylcyclopropane Chemical compound CCC1C(CC)C1C=C ZSOAZJCWMJEXKS-UHFFFAOYSA-N 0.000 abstract 1
- IYVVUTGMXRNCRS-UHFFFAOYSA-N 2-ethenyl-1-ethoxycarbonylcyclopropane-1-carboxylic acid Chemical compound CCOC(=O)C1(C(O)=O)CC1C=C IYVVUTGMXRNCRS-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 208000005176 Hepatitis C Diseases 0.000 abstract 1
- -1 alkoxycarbonyl 2 vinylcyclopropanecarboxylic acid Chemical compound 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- YIWFBNMYFYINAD-UHFFFAOYSA-N ethenylcyclopropane Chemical compound C=CC1CC1 YIWFBNMYFYINAD-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010194630 | 2010-08-31 | ||
| PCT/JP2011/069680 WO2012029819A1 (ja) | 2010-08-31 | 2011-08-31 | 新規加水分解酵素タンパク質 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2013CN00757A true IN2013CN00757A (https=) | 2015-04-24 |
Family
ID=45772898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN757CHN2013 IN2013CN00757A (https=) | 2010-08-31 | 2011-08-31 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9029107B2 (https=) |
| EP (1) | EP2612913B1 (https=) |
| JP (1) | JP5657560B2 (https=) |
| CN (1) | CN102834515B (https=) |
| IN (1) | IN2013CN00757A (https=) |
| SG (1) | SG187652A1 (https=) |
| WO (1) | WO2012029819A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9029107B2 (en) | 2010-08-31 | 2015-05-12 | Api Corporation | Hydrolase protein |
| WO2013137330A1 (ja) * | 2012-03-14 | 2013-09-19 | 積水メディカル株式会社 | 光学活性２－ビニルシクロプロパン－１，１－ジカルボン酸エステルの製造法 |
| ES2693568T3 (es) | 2012-12-20 | 2018-12-12 | Api Corporation | Método para producir un derivado de ácido cis-5-hidroxi-2-piperidincarboxílico, y método para purificar ácido cis-5-hidroxi-2-piperidincarboxílico |
| EP2946006B1 (en) * | 2013-01-18 | 2019-04-10 | Codexis, Inc. | Engineered biocatalysts useful for carbapenem synthesis |
| CN104685061B (zh) | 2013-02-19 | 2018-05-01 | 株式会社Api | L-赖氨酸羟化酶和利用了该l-赖氨酸羟化酶的羟基-l-赖氨酸的制造法及羟基-l-2-哌啶酸的制造法 |
| TWI758313B (zh) * | 2016-10-12 | 2022-03-21 | 美商陶氏農業科學公司 | 一種用於製備(1r,3r)-及(1s,3s)-2,2-二鹵基-3-(經取代之苯基)環丙烷甲酸的方法 |
| DK3607097T3 (da) * | 2017-04-07 | 2023-09-18 | Dupont Nutrition Biosci Aps | Bacillus-værtsceller, der danner beta-galactosidaser og lactaser i fravær af p-nitrobenzylesterase-sideaktivitet |
| US11572551B2 (en) | 2018-03-30 | 2023-02-07 | Api Corporation | Hydrolase and method for producing (1S,2S)-1-alkoxycarbonyl-2-vinylcyclopropane carboxylic acid using same |
| CN110283804A (zh) * | 2019-07-18 | 2019-09-27 | 江苏省农业科学院 | 酯酶基因及编码蛋白与应用 |
| JP7772363B2 (ja) * | 2019-11-29 | 2025-11-18 | 日本マイクロバイオファーマ株式会社 | メイタンシノールの酵素的生産方法 |
| CN114480343B (zh) * | 2020-10-27 | 2023-07-04 | 湖北大学 | 具提升活性的pet水解酶 |
| CN114763567A (zh) * | 2020-12-31 | 2022-07-19 | 上海合全药物研发有限公司 | 一种使用酯水解酶及其突变体对潜手性二酯的去对称化方法 |
| CN115109765B (zh) * | 2022-06-24 | 2023-10-13 | 浙江工业大学 | 酯酶pnbA-BS突变体及其在制备l-薄荷醇中的应用 |
| CN116555222B (zh) * | 2023-05-17 | 2026-04-14 | 南京师范大学 | 2-羟乙基对苯二甲酸二酯水解酶突变体及编码基因、重组载体、重组菌株、酶制剂和应用 |
| CN116987653A (zh) * | 2023-08-03 | 2023-11-03 | 南京工业大学 | 一种表达牛乳铁蛋白的解淀粉芽孢杆菌及其构建方法与应用 |
| CN121204014B (zh) * | 2025-11-26 | 2026-03-20 | 中国科学院苏州生物医学工程技术研究所 | 高对映选择性的水合蒎醇酯酶突变体、其构建方法及应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
| US5750380A (en) | 1981-06-30 | 1998-05-12 | City Of Hope Research Institute | DNA polymerase mediated synthesis of double stranded nucleic acids |
| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドｐｃｇ２ |
| JPS5867679A (ja) | 1981-09-30 | 1983-04-22 | アメリカン・サイアナミド・カンパニ− | イソシアン酸を三量化してシアヌル酸をつくる方法 |
| JPS5877895A (ja) | 1981-11-02 | 1983-05-11 | Ajinomoto Co Inc | プラスミドｐｈｍ１５１９ |
| JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
| US5180671A (en) | 1986-04-16 | 1993-01-19 | Sumitomo Chemical Company, Limited | Method for producing optically active cyclopropane carboxylic acid |
| JPH0679557B2 (ja) | 1986-04-16 | 1994-10-12 | 住友化学工業株式会社 | 光学活性なシス−シクロプロパンカルボン酸の製造方法 |
| EP0264457B1 (en) | 1986-04-16 | 1993-03-31 | Sumitomo Chemical Company, Limited | Process for preparing optically active cyclopropanecarboxylic acids |
| JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
| JP2522538B2 (ja) | 1989-01-31 | 1996-08-07 | 株式会社紀文食品 | 耐熱性の高いヌクレア―ゼ画分の製造方法 |
| JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
| US5468632A (en) * | 1991-12-20 | 1995-11-21 | Eli Lilly And Company | Recombinant DNA compounds and expression vectors encoding para-nitrobenzyl esterase activity from bacillus |
| US5741691A (en) | 1996-01-23 | 1998-04-21 | California Institute Of Technology | Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media |
| DE19736591A1 (de) | 1997-08-22 | 1999-02-25 | Peter Prof Dr Hegemann | Verfahren zum Herstellen von Nukleinsäurepolymeren |
| US5945325A (en) * | 1998-04-20 | 1999-08-31 | California Institute Of Technology | Thermally stable para-nitrobenzyl esterases |
| JP2005034025A (ja) | 2003-07-18 | 2005-02-10 | Mitsubishi Pharma Corp | 大腸菌での異種遺伝子発現を促進させるプラスミドベクター、組換え大腸菌、該組換え大腸菌を用いた化学物質製造法及び組換えタンパク質の製造法 |
| JP4763462B2 (ja) | 2004-02-04 | 2011-08-31 | 株式会社エーピーアイ コーポレーション | 光学活性を有するアルコール及びカルボン酸の製造方法 |
| DE102005037659A1 (de) | 2005-08-05 | 2007-02-22 | Henkel Kgaa | Verwendung von Esterasen zur Spaltung von Kunststoffen |
| CN102834370B (zh) * | 2010-02-16 | 2016-11-23 | 株式会社Api | 1-氨基-1-烷氧基羰基-2-乙烯基环丙烷的制备方法 |
| US9029107B2 (en) | 2010-08-31 | 2015-05-12 | Api Corporation | Hydrolase protein |
-
2011
- 2011-08-31 US US13/813,047 patent/US9029107B2/en active Active
- 2011-08-31 IN IN757CHN2013 patent/IN2013CN00757A/en unknown
- 2011-08-31 WO PCT/JP2011/069680 patent/WO2012029819A1/ja not_active Ceased
- 2011-08-31 SG SG2013007422A patent/SG187652A1/en unknown
- 2011-08-31 JP JP2011539573A patent/JP5657560B2/ja active Active
- 2011-08-31 CN CN201180009868.2A patent/CN102834515B/zh active Active
- 2011-08-31 EP EP11821834.6A patent/EP2612913B1/en active Active
-
2015
- 2015-03-04 US US14/637,429 patent/US9334509B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2012029819A1 (ja) | 2013-10-31 |
| US20150252393A1 (en) | 2015-09-10 |
| US9029107B2 (en) | 2015-05-12 |
| JP5657560B2 (ja) | 2015-01-21 |
| EP2612913A1 (en) | 2013-07-10 |
| EP2612913B1 (en) | 2016-07-27 |
| SG187652A1 (en) | 2013-03-28 |
| CN102834515A (zh) | 2012-12-19 |
| US20130130338A1 (en) | 2013-05-23 |
| EP2612913A4 (en) | 2014-03-26 |
| CN102834515B (zh) | 2016-08-03 |
| WO2012029819A1 (ja) | 2012-03-08 |
| US9334509B2 (en) | 2016-05-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2013CN00757A (https=) | ||
| MY170507A (en) | A microorganism having enhanced l-amino acids productivity and process for producing l-amino acids using the same | |
| MY158663A (en) | Fermentation broth formulations | |
| PH12013500759B1 (en) | O-phosphoserine sulfhydrylase mutants and method for production of cysteine using the same | |
| IN2014CN01614A (https=) | ||
| EA201101312A1 (ru) | Получение адипиновой кислоты | |
| MY172307A (en) | Production of muconic acid from genetically engineered microorganisms | |
| MX2012007224A (es) | Metodos para mejorar la eficacia de las reacciones de sacarificacion y fermentacion simultaneas. | |
| WO2013108044A8 (en) | Norbornene modified peptides and their labelling with tetrazine compounds | |
| WO2014072785A8 (en) | A process for the preparation of pregabalin | |
| MX2012001157A (es) | Procedimiento para la preparacion de 2,2-difluoroetilamina. | |
| TW200833657A (en) | Novel process | |
| MX336483B (es) | Procedimiento para preparar soluciones acuosas de sales trialcalinometalicas de acido metilglicin - n, n - diacetico. | |
| PH12012501438A1 (en) | Method for preparing tetrazole methanesulfonic acid salts, and novel compound used in same | |
| IN2014KN00866A (https=) | ||
| IN2013CN00459A (https=) | ||
| WO2012087038A3 (ko) | 신규 ｏ-아세틸호모세린 설피드릴라아제 또는 이의 변이체 및 이를 이용한 메치오닌 전환 방법 | |
| PH12013500343A1 (en) | Production method of intermediate compound for synthesizing medicament | |
| WO2012008785A3 (ko) | 라말린의 합성방법 | |
| NZ605608A (en) | Method of synthesis of ferroquine by convergent reductive amination | |
| EA201300646A1 (ru) | Способ получения небиволола | |
| EP3604273A3 (en) | Process for the synthesis of highly pure cationic surfactant products | |
| MX348766B (es) | Metodo de expresion. | |
| GB201104203D0 (en) | Chemical process | |
| SG179201A1 (en) | Synthesis of (4-fluoro-3-piperidin-4-yl-benzyl)-carbamic acid tert-butyl ester and intermediates thereof |