IN2012DN06589A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN06589A IN2012DN06589A IN6589DEN2012A IN2012DN06589A IN 2012DN06589 A IN2012DN06589 A IN 2012DN06589A IN 6589DEN2012 A IN6589DEN2012 A IN 6589DEN2012A IN 2012DN06589 A IN2012DN06589 A IN 2012DN06589A
- Authority
- IN
- India
- Prior art keywords
- mbl
- sepsis
- infectious diseases
- provides
- bind
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4726—Lectins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56961—Plant cells or fungi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/66—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a swap of domains, e.g. CH3-CH2, VH-CL or VL-CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
- G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
- G01N2333/40—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Candida
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29622210P | 2010-01-19 | 2010-01-19 | |
PCT/US2011/021603 WO2011090954A2 (fr) | 2010-01-19 | 2011-01-19 | Opsonine obtenue par génie génétique, pour la détection et le traitement de micro-organismes pathogènes |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN06589A true IN2012DN06589A (fr) | 2015-10-23 |
Family
ID=44307537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN6589DEN2012 IN2012DN06589A (fr) | 2010-01-19 | 2011-01-19 |
Country Status (11)
Country | Link |
---|---|
US (7) | US9150631B2 (fr) |
EP (1) | EP2526119B1 (fr) |
JP (5) | JP5959440B2 (fr) |
CN (1) | CN102947341B (fr) |
AU (1) | AU2011207626B2 (fr) |
CA (1) | CA2787376A1 (fr) |
DK (1) | DK2526119T3 (fr) |
ES (1) | ES2678143T3 (fr) |
IN (1) | IN2012DN06589A (fr) |
SG (2) | SG182577A1 (fr) |
WO (1) | WO2011090954A2 (fr) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007044642A2 (fr) | 2005-10-06 | 2007-04-19 | President And Fellows Of Harvard College And Children's Medical Center Corporation | Dispositif et procede destines a la separation microfluidique-micromagnetique combinee d'une substance a partir d'un ecoulement continu |
ATE534415T1 (de) | 2005-12-13 | 2011-12-15 | Harvard College | Gerüste zur zelltransplantation |
CN102006891B (zh) | 2008-02-13 | 2017-04-26 | 哈佛学院董事会 | 连续的细胞程序化装置 |
WO2010123594A2 (fr) | 2009-01-15 | 2010-10-28 | Children's Medical Center Corporation | Dispositif pour la filtration de fluides à travers celui-ci et procédé associé |
EP2526119B1 (fr) | 2010-01-19 | 2018-05-30 | President and Fellows of Harvard College | Opsonine obtenue par génie génétique, pour la détection et le traitement de micro-organismes pathogènes |
JP6104806B2 (ja) | 2010-10-06 | 2017-03-29 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル |
US20120263771A1 (en) * | 2011-03-25 | 2012-10-18 | Receptors Llc | Fiber with microbial removal, micro-biocidal, or static growth capability |
US20140220617A1 (en) * | 2011-04-01 | 2014-08-07 | Children's Medical Center Corporation | Dialysis like therapeutic (dlt) device |
AU2012284097B2 (en) | 2011-07-18 | 2017-08-03 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
WO2013130875A1 (fr) * | 2012-02-29 | 2013-09-06 | President And Fellows Of Harvard College | Test rapide de sensibilité aux antibiotiques |
EP3662896B1 (fr) | 2012-04-16 | 2024-02-28 | President and Fellows of Harvard College | Compositions de silice mésoporeuse pour moduler les réponses immunitaires |
US20130334120A1 (en) * | 2012-06-15 | 2013-12-19 | President And Fellows Of Harvard College | Fluid cleansing devices and methods of use |
EP3327090A1 (fr) * | 2012-07-18 | 2018-05-30 | President and Fellows of Harvard College | Modification de surfaces pour une répulsion et une liaison ciblée simultanées de fractions désirées |
US10551379B2 (en) | 2013-03-15 | 2020-02-04 | President And Fellows Of Harvard College | Methods and compositions for improving detection and/or capture of a target entity |
EP3848044A1 (fr) | 2013-05-21 | 2021-07-14 | President and Fellows of Harvard College | Compositions se liant à l'hème manipulées et leurs utilisations |
US9791440B2 (en) | 2013-07-15 | 2017-10-17 | President And Fellows Of Harvard College | Assays for antimicrobial activity and applications thereof |
US10513546B2 (en) | 2013-12-18 | 2019-12-24 | President And Fellows Of Harvard College | CRP capture/detection of gram positive bacteria |
DE102014206444A1 (de) * | 2014-04-03 | 2015-10-08 | Siemens Aktiengesellschaft | Verfahren für die Molekulardiagnostik zum Anreichern einer Nukleinsäure aus einer biologischen Probe |
WO2015168379A2 (fr) | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Dispositifs de vaccin combiné et procédés de destruction de cellules cancéreuses |
US10357780B2 (en) | 2014-10-27 | 2019-07-23 | President And Fellows Of Harvard College | Magnetic capture of a target from a fluid |
WO2016123573A1 (fr) | 2015-01-30 | 2016-08-04 | President And Fellows Of Harvard College | Matériaux péritumoraux et intratumoraux pour traitement anticancéreux |
WO2016164705A1 (fr) | 2015-04-10 | 2016-10-13 | Omar Abdel-Rahman Ali | Dispositifs de piégeage de cellules immunitaires et leurs procédés de fabrication et d'utilisation |
US10435457B2 (en) | 2015-08-06 | 2019-10-08 | President And Fellows Of Harvard College | Microbe-binding molecules and uses thereof |
EP3349823B1 (fr) | 2015-09-14 | 2022-01-26 | Medisieve Ltd | Appareil de filtration magnétique |
CN115487351A (zh) | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
WO2017143024A2 (fr) * | 2016-02-16 | 2017-08-24 | President And Fellows Of Harvard College | Vaccins contre des agents pathogènes et leurs procédés de production et d'utilisation |
US11919971B2 (en) | 2016-05-16 | 2024-03-05 | President And Fellows Of Harvard College | Aqueous biomolecule coupling on CO2-plasma-activated surfaces |
CN109789092A (zh) | 2016-07-13 | 2019-05-21 | 哈佛学院院长等 | 抗原呈递细胞模拟支架及其制备和使用方法 |
JP7071040B2 (ja) | 2016-07-28 | 2022-05-18 | メディシーブ リミテッド | 磁性混合器および方法 |
WO2019064463A1 (fr) * | 2017-09-28 | 2019-04-04 | 学校法人中部大学 | Procédé et dispositif pour la concentration de virus ou de bactérie par bioaffinité |
KR102084688B1 (ko) * | 2018-06-18 | 2020-03-04 | 울산과학기술원 | 다중 프로브 혼성화를 이용한 미생물 검출 방법 |
CN110628624B (zh) * | 2019-02-01 | 2022-07-15 | 传鸣(宁波)化学科技有限公司 | 一种磁性微生物捕获材料及微生物捕获方法 |
CN110294810B (zh) * | 2019-06-26 | 2021-05-04 | 中国疾病预防控制中心传染病预防控制所 | 一种含有人IgG1Fc和甘露聚糖结合凝集素C端的重组蛋白 |
US20230270927A1 (en) | 2019-12-23 | 2023-08-31 | Miraki Innovation Think Tank Llc | Compositions, devices and methods for diagnosing and treating infectious disease |
US20230054472A1 (en) | 2019-12-23 | 2023-02-23 | Miraki Innovation Think Tank Llc | Sample preparation and microbial analysis |
CN111675825B (zh) * | 2020-06-09 | 2022-06-24 | 大连工业大学 | 一种附有胰蛋白酶的微孔膜的制备方法及其在蛋白水解中的应用 |
CA3196472A1 (fr) | 2020-06-12 | 2021-12-16 | Miraki Innovation Think Tank Llc | Dosage a ecoulement lateral pour la detection rapide d'agents pathogenes dans des echantillons |
US20240001019A1 (en) | 2020-07-31 | 2024-01-04 | Miraki Innovation Think Tank Llc | Mbl-coated substrates having anti-thrombogenic properties |
WO2022046558A1 (fr) | 2020-08-28 | 2022-03-03 | Miraki Innovation Think Tank Llc | Compositions thérapeutiques comprenant des molécules ciblant des microbes et leur utilisation dans des méthodes de prévention et de traitement d'une maladie infectieuse |
WO2022067006A1 (fr) | 2020-09-25 | 2022-03-31 | Miraki Innovation Think Tank Llc | Compositions, dispositifs et méthodes comprenant des molécules ciblant les microbes pour le diagnostic et le traitement d'une maladie infectieuse |
US20230416319A1 (en) | 2020-10-01 | 2023-12-28 | Miraki Innovation Think Tank Llc | Compositions, devices and methods for identifying, treating and preventing infectious disease using microbe-targeting molecules |
WO2022093935A1 (fr) | 2020-10-27 | 2022-05-05 | Miraki Innovation Think Tank Llc | Compositions, systèmes et méthodes de surveillance de pathogènes à l'aide de molécules ciblant des microbes |
WO2022125632A1 (fr) | 2020-12-08 | 2022-06-16 | Miraki Innovation Think Tank Llc | Cellules exprimant un récepteur antigénique chimérique pour cibler des motifs moléculaires associés aux microbes |
WO2022151333A1 (fr) * | 2021-01-15 | 2022-07-21 | 传鸣(宁波)化学科技有限公司 | Mélange pour enrichir des micro-organismes et procédé et application |
Family Cites Families (118)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5418198A (en) | 1977-07-09 | 1979-02-09 | Toshimitsu Niwa | Artificial intraretinal device |
US4425330A (en) | 1981-05-20 | 1984-01-10 | Cornell Research Foundation, Inc. | Bovine mastitis vaccine and method for detecting efficacy thereof |
WO1984002193A1 (fr) | 1982-12-03 | 1984-06-07 | Du Pont | Analyse immunologique a support chromogene |
JPS60500548A (ja) | 1982-12-03 | 1985-04-18 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | 発色性支持体免疫測定法 |
JPH0718875B2 (ja) | 1987-06-19 | 1995-03-06 | ヤマサ醤油株式会社 | 血中または体液中の微量物質含有量の測定法 |
US5270199A (en) | 1987-08-20 | 1993-12-14 | The Children's Medical Center Corporation | Human mannose-binding protein |
JP2868777B2 (ja) | 1987-08-20 | 1999-03-10 | チルドレンズ・ホスピタル・コーポレイション | ヒトマンノース結合タンパク質 |
ATE122568T1 (de) | 1989-01-25 | 1995-06-15 | Commw Scient Ind Res Org | Polypeptide, antigene oder vakzine gegen babesiosis. |
US5137810A (en) | 1989-04-26 | 1992-08-11 | The University Of North Carolina | Method of determining the gram sign of bacteria |
DE4018583A1 (de) | 1990-06-09 | 1991-12-12 | Henkel Kgaa | Modifiziertes verfahren zur direkten herstellung von alkylglykosiden |
EP0900521A1 (fr) | 1990-07-30 | 1999-03-10 | Novartis AG | Proteines insecticides |
GB9020075D0 (en) | 1990-09-14 | 1990-10-24 | Filler Aaron G | Contrast agents for magnetic resonance imaging of axonal transport |
JPH04130274A (ja) | 1990-09-20 | 1992-05-01 | Kyoto Ikagaku Kenkyusho:Kk | 糖蛋白の分析,検出方法 |
US5783179A (en) | 1991-08-09 | 1998-07-21 | Syntex (U.S.A.) Inc. | C-reactive protein fragment with immunomodulatory activity |
CA2123786C (fr) | 1991-11-27 | 2000-08-01 | Lawrence A. Potempa | Methode de traitement des viroses par proteine c-reactive |
US5405832A (en) | 1991-11-27 | 1995-04-11 | Immtech International Inc. | Method of treating non-streptococcal bacterial infections |
US5874238A (en) | 1993-02-26 | 1999-02-23 | Immtech International Inc. | Mutant protein and methods and materials for making and using it |
US5283238A (en) | 1992-04-24 | 1994-02-01 | Immtech International, Inc. | Methods of treating cancer using modified C-reactive protein |
US6703219B1 (en) | 1993-02-26 | 2004-03-09 | Immtech International Inc. | Mutant protein and methods and materials for making and using it |
IT1271486B (it) | 1993-10-12 | 1997-05-28 | Italfarmaco Spa | Oligopeptidi immunomodulatori derivati di frammenti della proteina c- reattiva |
US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
AUPN214095A0 (en) | 1995-04-03 | 1995-04-27 | Australian Water Technologies Pty Ltd | Method for detecting microorganisms using flow cytometry |
WO1997035619A1 (fr) | 1996-03-28 | 1997-10-02 | Genitrix, L.L.C. | Cellules renforcees par opsonine, et procede de modulation d'une reponse immune a un antigene |
ZA973051B (en) | 1996-04-24 | 1998-10-12 | Genentech Inc | Type c lectins |
US6117977A (en) | 1996-04-24 | 2000-09-12 | Genentech, Inc. | Type C lectins |
FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
US6294170B1 (en) * | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
IL121191A0 (en) | 1997-06-29 | 1997-11-20 | Yeda Res & Dev | Synthetic peptides and pharmaceutical compositions comprising them |
JPH11206378A (ja) | 1998-01-23 | 1999-08-03 | Fuso Pharmaceutical Industries Ltd | 組換えヒトマンナン結合タンパク質およびその製造方法 |
US7049099B2 (en) | 1998-01-23 | 2006-05-23 | Fuso Pharmaceutical Industries, Ltd. | Recombinant human mannan-binding proteins and producing method of the same |
US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
US6429192B1 (en) | 1998-06-10 | 2002-08-06 | Statens Serum Institut | Purification process for production of mannan-binding lectin and an MBL medicinal product |
NZ509577A (en) | 1998-07-31 | 2003-01-31 | Asahi Chemical Ind | Antibodies for ribosmal proteins specific to only one microorganism genus or species |
US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
DE60033147T2 (de) | 1999-05-14 | 2007-12-13 | Steffen Thiel | Rekombinantes menschliches mannan-bindendes lektin |
ES2317843T3 (es) | 1999-07-13 | 2009-05-01 | Bolder Biotechnology, Inc. | Proteinas de fusion de eritropoyetina-inmunoglobulina. |
US6503761B1 (en) | 1999-10-19 | 2003-01-07 | Kimberly-Clark Worldwide, Inc. | Selective removal of contaminants from a surface using articles having magnets |
MXPA02007733A (es) * | 2000-02-11 | 2004-09-10 | Merck Patent Gmbh | Mejoramiento de la vida media circulante de proteinas de fusion basadas en anticuerpos. |
US6471968B1 (en) | 2000-05-12 | 2002-10-29 | Regents Of The University Of Michigan | Multifunctional nanodevice platform |
JP2002165591A (ja) | 2000-09-25 | 2002-06-11 | Jsr Corp | 磁性粒子およびその使用方法 |
AU2002227184A1 (en) | 2000-10-18 | 2002-04-29 | The Board Of Trustess Of The Leland Stanford Junior University | Methods for development and use of diagnostic and therapeutic agents |
GB0119274D0 (en) | 2001-08-08 | 2001-10-03 | Univ Durham | Fusion proteins for insect control |
US6900292B2 (en) * | 2001-08-17 | 2005-05-31 | Lee-Hwei K. Sun | Fc fusion proteins of human erythropoietin with increased biological activities |
WO2003054164A2 (fr) | 2001-12-19 | 2003-07-03 | Immunex Corporation | Polypeptide de lectine de type c, polynucleotide et procedes de fabrication et d'utilisation correspondant |
US6844426B2 (en) | 2002-02-06 | 2005-01-18 | Toyo Boseki Kabushiki Kaisha | Magnetic carrier capable of binding with protein and purification method of protein utilizing the magnetic carrier |
JP4959110B2 (ja) | 2002-02-07 | 2012-06-20 | マサチューセッツ インスティテュート オブ テクノロジー | 抗病原体治療 |
ES2271515T3 (es) | 2002-03-15 | 2007-04-16 | Natimmune A/S | Composiciones farmaceuticas que comprenden lecitina de union a manosa. |
US20030180814A1 (en) | 2002-03-21 | 2003-09-25 | Alastair Hodges | Direct immunosensor assay |
US7211396B2 (en) | 2002-04-18 | 2007-05-01 | Antibodyshop A/S | Antibody pairs and kits for immunochemical determination of mannan-binding lectin |
US20050037949A1 (en) | 2002-04-24 | 2005-02-17 | O'brien Grace | Mannose binding lectin and uses thereof |
US20040018611A1 (en) | 2002-07-23 | 2004-01-29 | Ward Michael Dennis | Microfluidic devices for high gradient magnetic separation |
US7629440B2 (en) | 2002-08-20 | 2009-12-08 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
BR0313650A (pt) * | 2002-08-20 | 2007-08-14 | Genitrix Llc | composição, vetor de expressão, composição de vacina e uso |
WO2004024925A2 (fr) | 2002-09-10 | 2004-03-25 | Natimmune A/S | Proteines chimeres activant la collectine du complement |
GB2393728A (en) | 2002-10-04 | 2004-04-07 | Nanomagnetics Ltd | Magnetic nanoparticles |
EP1417965A1 (fr) | 2002-11-07 | 2004-05-12 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Molécules capables de se lier à des lectines de type-C, leur identification et usages |
JP2007525232A (ja) | 2003-01-17 | 2007-09-06 | イースロン メディカル インコーポレイテッド | レクチンアフィニティー血液透析による血液のウイルス除去方法 |
US20050014932A1 (en) | 2003-05-15 | 2005-01-20 | Iogenetics, Llc | Targeted biocides |
DE10325752A1 (de) | 2003-06-06 | 2004-12-30 | Faustus Forschungs Cie. Translational Cancer Research Gmbh | Lektin-Konjugate |
WO2005040194A2 (fr) | 2003-10-24 | 2005-05-06 | Ludwig Institute For Cancer Research | Methodes et compositions d'activation et d'inhibition de pdgf-c |
AU2004309063B2 (en) * | 2003-12-31 | 2010-10-28 | Merck Patent Gmbh | Fc-erythropoietin fusion protein with improved pharmacokinetics |
WO2005092925A2 (fr) | 2004-03-24 | 2005-10-06 | Xencor, Inc. | Variantes d'immunoglobuline a l'exterieur de la region fc |
SE0401033D0 (sv) | 2004-04-20 | 2004-04-20 | Amersham Biosciences Ab | Device and method for protein analysis |
WO2007001332A2 (fr) | 2004-08-04 | 2007-01-04 | University Of Massachusetts | Immunoadhesines anti-pathogene |
US20090269843A1 (en) | 2004-08-20 | 2009-10-29 | Novo Nordisk A/S | Hemopexin fusion proteins |
US20110098184A1 (en) | 2004-10-15 | 2011-04-28 | Day Anthony G | Competitve differntial screeing |
JP4592756B2 (ja) | 2004-10-28 | 2010-12-08 | ドゥビエル カンパニー リミテッド | 高分子形マンノース結合型レクチンの大量生産方法 |
US20060141547A1 (en) | 2004-11-16 | 2006-06-29 | Das Hasi R | Novel diagnostic marker, a diagnostic kit and a method for diagnosis of rheumatoid arthritis |
US7172906B2 (en) | 2004-11-16 | 2007-02-06 | Dade Behring Inc. | Reduction of non-specific binding in assays |
US8084275B2 (en) | 2005-02-08 | 2011-12-27 | Fujifilm Corporation | Magnetic composite body, production method thereof, method for removing substance with mannose on its surface, and method for concentrating substance with mannose on its surface |
JP2008535872A (ja) | 2005-04-11 | 2008-09-04 | ナットイムネ・アクティーゼルスカブ | 免疫障害を持つ個体の処置におけるマンナン結合レクチン(mbl)の新規癌適用 |
US20070031819A1 (en) | 2005-04-26 | 2007-02-08 | University Of Washington | Microfluidic systems for biological and molecular analysis and methods thereof |
BRPI0608766A8 (pt) | 2005-05-09 | 2018-04-17 | Biosphere Medical Sa | microsfera substancialmente esférica, composição, e, métodos para administração de medicamento e para embolização ativa em um mamífero |
US20070231833A1 (en) | 2005-05-23 | 2007-10-04 | Arcidiacono Steven M | Labeled antimicrobial peptides and method of using the same to detect microorganisms of interest |
TWI333959B (en) | 2005-08-31 | 2010-12-01 | Academia Sinica | Methods and reagents for the analysis and purification of polysaccharides |
CA2621632A1 (fr) | 2005-09-30 | 2007-04-12 | Caliper Life Sciences, Inc. | Dispositif microfluidique utilise pour purifier un constituant biologique au moyen de billes magnetiques |
WO2007044642A2 (fr) | 2005-10-06 | 2007-04-19 | President And Fellows Of Harvard College And Children's Medical Center Corporation | Dispositif et procede destines a la separation microfluidique-micromagnetique combinee d'une substance a partir d'un ecoulement continu |
EP2388013A3 (fr) | 2005-10-26 | 2012-03-07 | Science & Technology Corporation @ UNM | Protéine C réactive et son utilisation pour traiter le lupus érythémateux systémique et des maladies associées |
US20070269818A1 (en) | 2005-12-28 | 2007-11-22 | Affymetrix, Inc. | Carbohydrate arrays |
US20090181041A1 (en) | 2006-01-23 | 2009-07-16 | Jan Holgersson | Production of proteins carrying oligomannose or human-like glycans in yeast and methods of use thereof |
CA2641271A1 (fr) | 2006-02-03 | 2008-03-13 | Microchip Biotechnologies, Inc. | Dispositifs microfluidiques |
US8821851B2 (en) | 2006-03-23 | 2014-09-02 | The General Hospital Corporation | Inflammation-inhibitory serum factors and uses thereof |
WO2007111496A1 (fr) * | 2006-03-28 | 2007-10-04 | Universiteit Utrecht Holding B.V. | Domaines de reconnaissance d'hydrates de carbone améliorés |
EP1862541A1 (fr) | 2006-06-01 | 2007-12-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Polypeptides dérivés du domaine de type hémopexine de la métalloprotéinase MMP-2 |
US8273310B2 (en) | 2006-09-05 | 2012-09-25 | Samsung Electronics Co., Ltd. | Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device |
KR101343034B1 (ko) | 2006-09-05 | 2013-12-18 | 삼성전자 주식회사 | 원심력 기반의 단백질 검출용 미세유동 장치 및 이를포함하는 미세유동 시스템 |
US8088596B2 (en) * | 2006-10-10 | 2012-01-03 | Oakland University | Method of microorganism detection using carbohydrate and lectin recognition |
US8551333B2 (en) | 2007-04-05 | 2013-10-08 | The Regents Of The University Of California | Particle-based microfluidic device for providing high magnetic field gradients |
WO2008131242A1 (fr) | 2007-04-18 | 2008-10-30 | Zymogenetics, Inc. | Fc à chaîne simple, procédés de fabrication et procédés de traitement |
US8292083B2 (en) | 2007-04-19 | 2012-10-23 | The Charles Stark Draper Laboratory, Inc. | Method and apparatus for separating particles, cells, molecules and particulates |
NZ581395A (en) | 2007-05-14 | 2012-08-31 | Biogen Idec Inc | Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto |
EP2162472B1 (fr) | 2007-05-30 | 2013-02-27 | Postech Academy-Industry- Foundation | Protéines de fusion d'immunoglobuline |
CA2698691A1 (fr) | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Utilisation d'un peptide en tant qu'agent therapeutique |
EP2662384A1 (fr) | 2007-10-29 | 2013-11-13 | Virginia Tech Intellectual Properties, Inc. | Utilisations de DC-SIGN ET LSECtin porcines, |
CA2705160A1 (fr) | 2007-11-09 | 2009-05-14 | Anaphore, Inc. | Proteines de fusion de lectines liant le mannose pour un traitement de maladie |
ES2326109B1 (es) | 2007-12-05 | 2010-06-25 | Consejo Superior De Investigaciones Cientificas | Microdispositivo de separacion y extraccion selectiva y no invasiva de particulas en suspensiones polidispersas, procedimiento de fabricacion y sus aplicaciones. |
WO2009078015A2 (fr) | 2007-12-18 | 2009-06-25 | Procognia (Israel) Ltd | Procédé et dosage pour la détection de motifs de glycosylation reliés à l'état cellulaire de cellules souches |
EP2240774A2 (fr) | 2007-12-31 | 2010-10-20 | 3M Innovative Properties Company | Compositions et procédés de capture de micro-organismes |
US20100331240A1 (en) | 2008-01-18 | 2010-12-30 | The General Hospital Corporation | Methods for prevention and treatment of infections with supraphysiological doses of mannan-binding lectin (mbl) and ficolin-mbl fusion proteins |
CN101990575B (zh) | 2008-03-28 | 2015-06-17 | 国立大学法人北海道大学 | 抗h5亚型a型流感病毒血凝素单克隆抗体 |
JPWO2009123347A1 (ja) | 2008-03-31 | 2011-07-28 | 日本たばこ産業株式会社 | ウイルス定量法 |
EP2267119A4 (fr) | 2008-03-31 | 2011-05-25 | Japan Tobacco Inc | Procédé de concentration de virus |
US20100323429A1 (en) | 2008-04-10 | 2010-12-23 | Yu-Chen Hu | Methods for purifying baculovirus |
US8865876B2 (en) | 2008-06-02 | 2014-10-21 | California Institute Of Technology | Engineered lectin oligomers with antiviral activity |
BRPI0909910A2 (pt) | 2008-06-03 | 2016-10-11 | Stc Unm | "método de tratamento, inibição ou redução da probabilidade de lúpus eritematoso sistêmico (les) ou de um estado de doença secundária, condição ou manifestação associada ao lúpus eritematoso sistêmico ou à púrpura trombocitopênica imunológica em um paciente, composição farmacêutica e seu uso" |
JP2010122205A (ja) | 2008-08-29 | 2010-06-03 | Sysmex Corp | 麻疹ウイルス検出方法、メンブレンアッセイ用試験具およびメンブレンアッセイ用試験キット |
US20110159000A1 (en) | 2008-09-05 | 2011-06-30 | The Regents Of The University Of California | Antibodies with mannose binding lectin effector function for inhibiting pathologic inflammatory conditions |
WO2010065765A2 (fr) | 2008-12-04 | 2010-06-10 | Aethlon Medical, Inc. | Capture par affinité de biomarqueurs circulants |
JP5645187B2 (ja) | 2008-12-22 | 2014-12-24 | 国立大学法人北海道大学 | 三重螺旋構造を有するタンパク質、およびその製造方法 |
WO2010078966A1 (fr) * | 2009-01-09 | 2010-07-15 | Apogenix Gmbh | Protéines de fusion formant des trimères |
JP2012515556A (ja) | 2009-01-23 | 2012-07-12 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 低下したエフェクタ機能を有する安定化Fcポリペプチドおよび使用方法 |
CA2750115A1 (fr) | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Lectines de site de liaison modifiees et usage correspondant |
WO2011084749A1 (fr) | 2009-12-21 | 2011-07-14 | The Research Foundation Of State University Of New York | Compositions et méthodes permettant d'inhiber la migration cellulaire à médiation par la mmp9 |
WO2011091037A2 (fr) | 2010-01-19 | 2011-07-28 | President And Fellows Of Harvard College | Dispositif et procédé de diagnostic pathogène rapide |
EP2526119B1 (fr) | 2010-01-19 | 2018-05-30 | President and Fellows of Harvard College | Opsonine obtenue par génie génétique, pour la détection et le traitement de micro-organismes pathogènes |
EP2665782A2 (fr) | 2011-01-19 | 2013-11-27 | President and Fellows of Harvard College | Surfaces glissantes à stabilité élevée à la pression possédant des caractéristiques de transparence optique et auto-réparatrices |
US20140220617A1 (en) | 2011-04-01 | 2014-08-07 | Children's Medical Center Corporation | Dialysis like therapeutic (dlt) device |
AU2012284097B2 (en) | 2011-07-18 | 2017-08-03 | President And Fellows Of Harvard College | Engineered microbe-targeting molecules and uses thereof |
-
2011
- 2011-01-19 EP EP11735056.1A patent/EP2526119B1/fr active Active
- 2011-01-19 AU AU2011207626A patent/AU2011207626B2/en active Active
- 2011-01-19 SG SG2012052965A patent/SG182577A1/en unknown
- 2011-01-19 ES ES11735056.1T patent/ES2678143T3/es active Active
- 2011-01-19 SG SG10201503351RA patent/SG10201503351RA/en unknown
- 2011-01-19 CN CN201180014755.1A patent/CN102947341B/zh active Active
- 2011-01-19 JP JP2012550067A patent/JP5959440B2/ja active Active
- 2011-01-19 US US13/574,191 patent/US9150631B2/en active Active
- 2011-01-19 IN IN6589DEN2012 patent/IN2012DN06589A/en unknown
- 2011-01-19 CA CA2787376A patent/CA2787376A1/fr active Pending
- 2011-01-19 DK DK11735056.1T patent/DK2526119T3/en active
- 2011-01-19 WO PCT/US2011/021603 patent/WO2011090954A2/fr active Application Filing
-
2015
- 2015-08-20 US US14/831,480 patent/US20160200785A1/en not_active Abandoned
-
2016
- 2016-06-21 JP JP2016122230A patent/JP6513604B2/ja active Active
-
2017
- 2017-12-12 US US15/839,352 patent/US10538562B2/en active Active
-
2019
- 2019-04-10 JP JP2019074496A patent/JP6960957B2/ja active Active
- 2019-12-04 US US16/702,724 patent/US11059873B2/en active Active
-
2020
- 2020-06-04 US US16/892,577 patent/US11059874B2/en active Active
- 2020-06-04 US US16/892,575 patent/US11203623B2/en active Active
- 2020-07-14 JP JP2020120294A patent/JP7062723B2/ja active Active
-
2021
- 2021-11-09 US US17/522,115 patent/US20220056089A1/en active Pending
-
2022
- 2022-04-20 JP JP2022069222A patent/JP2022097536A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2012DN06589A (fr) | ||
CY1124488T1 (el) | Απελευθερωση πρωτεϊνης που βασιζεται σε εξασθενημενης λοιμογονικοτητας βακτηριδια | |
MY183517A (en) | Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof | |
PH12014501776A1 (en) | Human binding molecules capable of binding to and neutralizing influenza b viruses and uses thereof | |
MX366858B (es) | Composicion farmaceutica que comprende un complejo de carga con portador polimerico y al menos y un antigeno proteinico o peptidico. | |
BR112014023005A2 (pt) | diagnóstico rápido e tratamentos personalizados para acne | |
AU2012249274A8 (en) | Neutralizing antibodies to Nipah and Hendra virus | |
EA201001212A1 (ru) | Лечение микробных инфекций | |
CO6630164A2 (es) | Proteinas que se unen al tnf-a | |
IL187321A (en) | Molecules that have a specific link to a surrogate cell that encode monoclonal antibodies capable of neutralizing viruses, medicinal preparations containing them, and their uses in drug preparation | |
BRPI0708101A8 (pt) | anticorpos contra a il-22 humana e usos para eles | |
WO2018116267A3 (fr) | Méthodes de traitement avec des anticorps anti-facteur xi/xia | |
EA201491481A1 (ru) | Аллергены тимофеевки луговой и способы и применения для модулирования иммунного ответа | |
BR112017004059A2 (pt) | dispositivo de hemoperfusão utilizável | |
ATE503769T1 (de) | Antikörper gegen das humane cytomegalie-virus (hcmv) | |
MX2011004483A (es) | Leucolectinas y sus usos. | |
BR112014023642A2 (pt) | proteína interferon-lambda4 (ifnl4), moléculas de anticorpo relacionadas, e usos das mesmas | |
BR112019007147A2 (pt) | anticorpos anti-o1 e usos dos mesmos | |
CY1116962T1 (el) | Ανθρωπινες λευκολεκτινες και χρησεις αυτων | |
BR112014023063A2 (pt) | anticorpos que neutralizam rsv, mpv e pvm e usos dos mesmos | |
BR112019002039A2 (pt) | anticorpos anti-o2 e uso dos mesmos | |
Al-Otair et al. | Venous thromboembolism in a medical intensive care unit. The effect of implementing clinical practice guidelines | |
BR112018003252A2 (pt) | polipeptídeos mrka, anticorpos, e usos dos mesmos | |
Ayubi et al. | Procalcitonin levels predict identification of bacterial strains in blood cultures of septic patients: effect measures of association | |
BR112022003623A2 (pt) | Proteínas de ligação a cr2 e seu uso em terapia médica |