IN2012DN02117A - - Google Patents
Download PDFInfo
- Publication number
- IN2012DN02117A IN2012DN02117A IN2117DEN2012A IN2012DN02117A IN 2012DN02117 A IN2012DN02117 A IN 2012DN02117A IN 2117DEN2012 A IN2117DEN2012 A IN 2117DEN2012A IN 2012DN02117 A IN2012DN02117 A IN 2012DN02117A
- Authority
- IN
- India
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01087—N-Acetyllactosaminide 3-alpha-galactosyltransferase (2.4.1.87), i.e. alpha-1,3-galactosyltransferase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/206—Animal model comprising tissue-specific expression system, e.g. tissue specific expression of transgene, of Cre recombinase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0362—Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/40—Vector systems having a special element relevant for transcription being an insulator
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23415009P | 2009-08-14 | 2009-08-14 | |
| PCT/US2010/045665 WO2011020120A2 (en) | 2009-08-14 | 2010-08-16 | Multi-transgenic pigs for diabetes treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02117A true IN2012DN02117A (de) | 2015-08-21 |
Family
ID=43586899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2117DEN2012 IN2012DN02117A (de) | 2009-08-14 | 2012-03-09 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9339519B2 (de) |
| EP (1) | EP2464219B1 (de) |
| JP (3) | JP2013501528A (de) |
| KR (3) | KR102122267B1 (de) |
| CN (2) | CN102548394A (de) |
| AU (3) | AU2010282239A1 (de) |
| CA (2) | CA2771299C (de) |
| ES (1) | ES2767881T3 (de) |
| IN (1) | IN2012DN02117A (de) |
| WO (1) | WO2011020120A2 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1924686A4 (de) | 2005-08-09 | 2009-11-11 | Revivicor Inc | Ctla4-ig exprimierende transgene huftiere und deren verwendung |
| US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
| AU2012255744A1 (en) * | 2011-05-16 | 2014-01-09 | The Curators Of The University Of Missouri | Porcine reproductive and respiratory syndrome virus resistant animals |
| WO2013063076A1 (en) * | 2011-10-25 | 2013-05-02 | Indiana University Research & Technology Corporation | Compositions for and methods of modulating complications, risks and issues with xenotransplantation |
| US20140112958A1 (en) * | 2012-10-24 | 2014-04-24 | Mwm Biomodels Gmbh | Pancreatic islets of transgenic LEA29Y animals for treating diabetes |
| US20140115728A1 (en) | 2012-10-24 | 2014-04-24 | A. Joseph Tector | Double knockout (gt/cmah-ko) pigs, organs and tissues |
| US20150139994A1 (en) * | 2013-11-12 | 2015-05-21 | The Regents Of The University Of California | Compositions and methods for preventing allogeneic immune rejection |
| CN103675291A (zh) * | 2013-11-25 | 2014-03-26 | 南昌大学 | 一种基于t细胞表位筛查低乳糜泻毒性小麦品种的方法 |
| JP6621420B2 (ja) * | 2014-04-11 | 2019-12-18 | ウニベルシテ カソリーク デ ルーベン | 糖尿病を治療するためのトランスジェニックブタ膵島およびその使用 |
| KR102656470B1 (ko) * | 2014-12-10 | 2024-04-09 | 리전츠 오브 더 유니버스티 오브 미네소타 | 질환을 치료하기 위한 유전적으로 변형된 세포, 조직 및 장기 |
| PT3282835T (pt) * | 2015-04-13 | 2023-07-25 | Univ Yale | Ratinhos knockin de sirpa-il15 humanizadas e métodos de utilização dos mesmos |
| BR112017025507A2 (pt) | 2015-05-29 | 2018-08-07 | Regeneron Pharmaceuticals, Inc. | roedor, célula isolada de roedor ou tecido isolado de roedor, célula-tronco embrionária de roedor, embrião de roedor, e, métodos para preparação de um roedor e para identificação de um candidato terapêutico. |
| EP4361279A3 (de) | 2015-08-06 | 2024-07-17 | The Curators of the University of Missouri | Pathogenresistente tiere mit modifizierten cd163-genen |
| JP6617495B2 (ja) * | 2015-09-18 | 2019-12-11 | 東ソー株式会社 | 腫瘍細胞の検出方法 |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| JP2019517803A (ja) * | 2016-06-14 | 2019-06-27 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 疾患を処置するための遺伝子改変された細胞、組織、および臓器 |
| RU2760877C2 (ru) * | 2016-09-30 | 2021-12-01 | Регенерон Фармасьютикалс, Инк. | Животные, отличные от человека, характеризующиеся экспансией гексануклеотидных повторов в локусе c9orf72 |
| CN110168089A (zh) * | 2016-10-07 | 2019-08-23 | 瑟卡尔纳制药有限公司 | 抑制cd39表达的免疫抑制恢复寡核苷酸 |
| KR101960414B1 (ko) * | 2016-11-11 | 2019-03-27 | 대한민국 | 사람 유래 dpp-4 유전자를 이용한 당뇨 질환 모델용 형질전환돼지 및 이의 용도 |
| JP6479246B1 (ja) * | 2017-09-19 | 2019-03-06 | 学校法人明治大学 | 特定の機能細胞を欠損する臓器を発達させる方法 |
| KR101833225B1 (ko) | 2017-09-26 | 2018-03-02 | 주식회사 엠젠플러스 | 인간 프로인슐린을 발현하는 형질전환 돼지 및 이의 제조방법 |
| US11160260B2 (en) | 2018-04-17 | 2021-11-02 | The Curators Of The University Of Missouri | Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV) |
| CN116889649A (zh) | 2018-10-05 | 2023-10-17 | 药物治疗股份有限公司 | 生物制品在制造用于人接受者的移植物中的应用 |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| AU2019403015B2 (en) | 2018-12-20 | 2024-01-18 | Regeneron Pharmaceuticals, Inc. | Nuclease-mediated repeat expansion |
| WO2020228043A1 (en) * | 2019-05-16 | 2020-11-19 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| WO2020228039A1 (en) * | 2019-05-16 | 2020-11-19 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| JP2022532783A (ja) * | 2019-05-16 | 2022-07-19 | イージェネシス，インコーポレイテッド | 向上した異種移植生存及び／又は耐性のための１つ以上の改変遺伝子を有する細胞、組織、器官、及び／又は動物 |
| WO2021072777A1 (en) * | 2019-10-18 | 2021-04-22 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| WO2021072778A1 (en) * | 2019-10-18 | 2021-04-22 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| CN115605585A (zh) * | 2020-01-07 | 2023-01-13 | 杭州启函生物科技有限公司（Cn） | 产生异种胰岛细胞和用所述异种胰岛细胞治疗胰岛素抗性或缺乏性病症的方法和组合物 |
| CN113429475A (zh) * | 2020-03-23 | 2021-09-24 | 成都中科奥格生物科技有限公司 | 一种胶原材料及其制备方法和用途 |
| US20230183649A1 (en) * | 2020-06-17 | 2023-06-15 | Otsuka Pharmaceutical Factory, Inc. | Encapsulated pancreatic islet |
| CN111955422A (zh) * | 2020-08-21 | 2020-11-20 | 五邑大学 | 一种可用于异种器官移植的供体猪的构建方法 |
| CN113016721A (zh) * | 2021-03-29 | 2021-06-25 | 何冬凌 | 中华眼镜蛇咬伤猪模型的制备及用途 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482404B1 (en) * | 1989-10-12 | 2002-11-19 | David James White | Transplantation of tissue comprising a DNA sequence encoding a homologous complement restriction factor |
| EP0495852B1 (de) | 1989-10-12 | 1996-06-19 | Imutran Limited | Modifiziertes biologisches material |
| US5859307A (en) * | 1992-02-04 | 1999-01-12 | Massachusetts Institute Of Technology | Mutant RAG-1 deficient animals having no mature B and T lymphocytes |
| US5578314A (en) * | 1992-05-29 | 1996-11-26 | The Regents Of The University Of California | Multiple layer alginate coatings of biological tissue for transplantation |
| WO1994021799A1 (en) | 1993-03-16 | 1994-09-29 | Austin Research Institute | USE OF PORCINE GAL α(1,3) GALACTOSYL TRANSFERASE IN XENOGRAFT THERAPIES |
| WO1995020661A1 (en) | 1994-01-27 | 1995-08-03 | Bresatec Ltd. | Materials and methods for management of hyperacute rejection in human xenotransplantation |
| JPH10504442A (ja) | 1994-04-13 | 1998-05-06 | バイオトランスプラント，インコーポレイテッド | α（１，３）ガラクトシルトランスフェラーゼ陰性ブタ |
| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| US6423316B1 (en) * | 1997-03-26 | 2002-07-23 | Imperial College Innovative Limited | Anticoagulant fusion protein anchored to cell membrane |
| GB9809280D0 (en) | 1998-04-30 | 1998-07-01 | Rpms Technology Ltd | Immunosupression |
| US20020012660A1 (en) * | 1999-03-04 | 2002-01-31 | Alan Colman | Method of preparing a somatic cells for nuclear transfer |
| US6303355B1 (en) * | 1999-03-22 | 2001-10-16 | Duke University | Method of culturing, cryopreserving and encapsulating pancreatic islet cells |
| AU1340101A (en) | 1999-10-22 | 2001-05-08 | Alexion Pharmaceuticals, Inc. | An engineered recombinant molecule that regulates humoral and cellular effector functions of the immune system |
| US7122177B2 (en) * | 2000-01-20 | 2006-10-17 | Diabcell Pty Ltd. | Preparation and xenotransplantation of porcine islets |
| DK1397153T3 (da) * | 2001-05-23 | 2008-05-26 | Bristol Myers Squibb Co | Fremgangsmåde til beskyttelse af allogent ö-celle-transplantat ved anvendelse af oplöselige CTLA4-mutantmolekyler |
| EP1465481A4 (de) | 2001-12-21 | 2007-09-12 | Univ Missouri | Knockout-schwein und seine herstellung |
| EP1534066A4 (de) | 2002-08-14 | 2008-01-02 | Immerge Biotherapeutics Inc | Alpha(1,3)-galactosyltransferase-nullzellen, selektionsverfahren und davon produziertes alpha(1,3)-galactosyltransferase-nullschwein |
| DE60330468D1 (de) * | 2002-08-21 | 2010-01-21 | Revivicor Inc | Schweine ohne jegliche expression funktioneller alpha-1,3-galactosyltransferase |
| US8106251B2 (en) * | 2002-08-21 | 2012-01-31 | Revivicor, Inc. | Tissue products derived from porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase |
| EP1718192A4 (de) * | 2003-11-26 | 2010-07-14 | Dana Farber Cancer Inst Inc | Tiermodelle für das adenocarcinom des pankreas und verwendungen dafür |
| CN1953657A (zh) * | 2004-03-17 | 2007-04-25 | 雷维维科公司 | 来源于缺乏任何功能性α1,3半乳糖基转移酶表达的动物的组织产品 |
| US7378569B2 (en) * | 2004-06-01 | 2008-05-27 | Animal Technology Institute Taiwan | Transgenic pigs carrying both hHO-1 and hDAF transgenes for xenotransplantation |
| EP1924686A4 (de) | 2005-08-09 | 2009-11-11 | Revivicor Inc | Ctla4-ig exprimierende transgene huftiere und deren verwendung |
| EP2348827B1 (de) * | 2008-10-27 | 2015-07-01 | Revivicor, Inc. | Immunsupprimierte huftiere |
-
2010
- 2010-08-16 WO PCT/US2010/045665 patent/WO2011020120A2/en active Application Filing
- 2010-08-16 KR KR1020197015948A patent/KR102122267B1/ko active IP Right Grant
- 2010-08-16 CA CA2771299A patent/CA2771299C/en active Active
- 2010-08-16 AU AU2010282239A patent/AU2010282239A1/en not_active Abandoned
- 2010-08-16 EP EP10808879.0A patent/EP2464219B1/de active Active
- 2010-08-16 ES ES10808879T patent/ES2767881T3/es active Active
- 2010-08-16 CN CN2010800457799A patent/CN102548394A/zh active Pending
- 2010-08-16 US US12/857,514 patent/US9339519B2/en active Active
- 2010-08-16 KR KR1020187009415A patent/KR20180036810A/ko active Application Filing
- 2010-08-16 CA CA3104704A patent/CA3104704A1/en active Pending
- 2010-08-16 KR KR1020127006683A patent/KR20120050485A/ko active Application Filing
- 2010-08-16 JP JP2012524939A patent/JP2013501528A/ja not_active Withdrawn
- 2010-08-16 CN CN201310552545.9A patent/CN103891675B/zh active Active
-
2012
- 2012-03-09 IN IN2117DEN2012 patent/IN2012DN02117A/en unknown
-
2016
- 2016-03-11 JP JP2016047895A patent/JP6525905B2/ja active Active
- 2016-05-05 US US15/147,228 patent/US10383317B2/en active Active
- 2016-06-16 AU AU2016204067A patent/AU2016204067B2/en active Active
-
2018
- 2018-05-14 AU AU2018203351A patent/AU2018203351B2/en active Active
- 2018-05-17 JP JP2018095246A patent/JP2018121663A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN103891675B (zh) | 2016-12-07 |
| KR102122267B1 (ko) | 2020-06-12 |
| EP2464219A4 (de) | 2013-08-21 |
| JP2016105730A (ja) | 2016-06-16 |
| KR20180036810A (ko) | 2018-04-09 |
| WO2011020120A3 (en) | 2011-04-07 |
| AU2010282239A1 (en) | 2012-03-08 |
| KR20190065475A (ko) | 2019-06-11 |
| KR20120050485A (ko) | 2012-05-18 |
| AU2016204067B2 (en) | 2018-02-15 |
| EP2464219B1 (de) | 2019-10-23 |
| CA3104704A1 (en) | 2011-02-17 |
| AU2016204067A1 (en) | 2016-07-07 |
| AU2018203351A1 (en) | 2018-05-31 |
| EP2464219A2 (de) | 2012-06-20 |
| WO2011020120A2 (en) | 2011-02-17 |
| AU2018203351B2 (en) | 2020-03-26 |
| US9339519B2 (en) | 2016-05-17 |
| CN102548394A (zh) | 2012-07-04 |
| JP2013501528A (ja) | 2013-01-17 |
| ES2767881T3 (es) | 2020-06-18 |
| US20160278350A1 (en) | 2016-09-29 |
| US10383317B2 (en) | 2019-08-20 |
| CA2771299C (en) | 2021-02-16 |
| CA2771299A1 (en) | 2011-02-17 |
| US20110038841A1 (en) | 2011-02-17 |
| CN103891675A (zh) | 2014-07-02 |
| JP6525905B2 (ja) | 2019-06-05 |
| JP2018121663A (ja) | 2018-08-09 |