IN2012DN01850A - - Google Patents

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Publication number
IN2012DN01850A
IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
Authority
IN
India
Prior art keywords
separation
line
units
fluid
separation unit
Prior art date
Application number
Other languages
English (en)
Inventor
M Williams Alan
Kaletski Adam
Stack Lisa
G Go Daniel
Krasnansky John
A Wareheim David
Lin Bin
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43779133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN01850(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Publication of IN2012DN01850A publication Critical patent/IN2012DN01850A/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
IN1850DEN2012 2009-09-25 2010-09-20 IN2012DN01850A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/566,701 US9527010B2 (en) 2009-09-25 2009-09-25 Separation system and method
PCT/SE2010/051003 WO2011037522A1 (en) 2009-09-25 2010-09-20 Separation system and method

Publications (1)

Publication Number Publication Date
IN2012DN01850A true IN2012DN01850A (zh) 2015-08-21

Family

ID=43779133

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1850DEN2012 IN2012DN01850A (zh) 2009-09-25 2010-09-20

Country Status (7)

Country Link
US (1) US9527010B2 (zh)
EP (1) EP2480305B1 (zh)
JP (1) JP5749270B2 (zh)
CN (1) CN102574026B (zh)
AU (1) AU2010298768B2 (zh)
IN (1) IN2012DN01850A (zh)
WO (1) WO2011037522A1 (zh)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011037530A1 (en) * 2009-09-25 2011-03-31 Ge Healthcare Bio-Sciences Ab Method and system for preparation of liquid mixtures
US20130131318A1 (en) * 2010-02-12 2013-05-23 Diderik Reinder Kremer Single unit antibody purification
CA2808116C (en) * 2010-07-30 2016-06-07 Pfizer Inc. Tandem purification of proteins
JP2012068244A (ja) * 2010-09-20 2012-04-05 Asahi Kasei Bioprocess Inc タンパク質の分離及び精製のための液体クロマトグラフィーのシステム及び方法
MX2013004720A (es) * 2010-11-01 2013-05-28 Dsm Ip Assets Bv Purificacion de anticuerpos mediante cromatografia de intercambio ionico de una uncia unidad.
JP2014529330A (ja) * 2011-06-16 2014-11-06 ディーエスエム アイピー アセッツ ビー．ブイ． 単一ユニットクロマトグラフィー抗体精製
WO2013028330A2 (en) 2011-08-19 2013-02-28 Emd Millipore Corporation Methods of reducing level of one of more impurities in a sample during protein purification
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
EP2776825B1 (en) * 2011-11-10 2024-06-19 F. Hoffmann-La Roche AG Preparative column chromatography system
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
EP3981873A1 (en) * 2012-06-29 2022-04-13 EMD Millipore Corporation Methods for inactivating viruses during a protein purification process
TWI631132B (zh) * 2013-05-06 2018-08-01 賽諾菲公司 用於純化抗體之連續多步驟方法
CN104237418B (zh) * 2013-09-11 2015-11-18 青岛普仁仪器有限公司 免稀释作线性曲线的色谱仪及线性曲线测量方法
EP3048109A4 (en) * 2013-09-17 2017-04-19 Kaneka Corporation Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom
EP3102934A1 (en) * 2014-02-07 2016-12-14 CMC Biologics A/S A chromatography system and method for capturing a biopolymer
JP6612242B2 (ja) * 2014-02-14 2019-11-27 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 自動化された多段階精製システム及び多段階クロマトグラフィー精製方法
JP6331485B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ及び液体クロマトグラフ分析方法
JP2017515501A (ja) * 2014-05-02 2017-06-15 ノヴォ ノルディスク アー／エス 統合型連続バイオマニュファクチャリング方法
US11835501B2 (en) 2015-07-13 2023-12-05 Sartorius Stedim Chromatography Systems Ltd. Optimizing operating binding capacity for a multiple column chromatography process
JP6579515B2 (ja) * 2015-08-10 2019-09-25 国立大学法人 岡山大学 アポｅ含有ｈｄｌの測定方法及び測定装置
SG11201808401QA (en) * 2016-04-04 2018-10-30 Boehringer Ingelheim Rcv Gmbh Real time monitoring of product purification
GB201622343D0 (en) * 2016-12-29 2017-02-15 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
US11016110B2 (en) 2017-01-26 2021-05-25 Myriad Women's Health, Inc. Reagent delivery and waste management system
US11185830B2 (en) 2017-09-06 2021-11-30 Waters Technologies Corporation Fluid mixer
FR3073424B1 (fr) 2017-11-16 2022-03-25 Novasep Process Procede regule de separation d’un melange
GB201802593D0 (en) * 2018-02-16 2018-04-04 Fujifilm Diosynth Biotechnologies Uk Ltd Rig
US20210024873A1 (en) * 2018-03-27 2021-01-28 Bristol-Myers Squibb Company Real-time monitoring of protein concentration using ultraviolet signal
CN109453545A (zh) * 2018-12-20 2019-03-12 上海兆维科技发展有限公司 层析柱洗脱液的配液装置
EP3693732A1 (en) * 2019-02-11 2020-08-12 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
EP3763429A1 (en) * 2019-07-08 2021-01-13 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
KR20210127702A (ko) * 2019-02-11 2021-10-22 바이엘 악티엔게젤샤프트 실시간 순차적 크로마토그래피에 대한 영향
EP3699697A1 (en) * 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automated simultaneous process control
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
CN114207433A (zh) 2019-08-12 2022-03-18 沃特世科技公司 用于色谱系统的混合器
GB201911686D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying target substances
GB201911685D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying monoclonal antibodies
WO2021061658A1 (en) * 2019-09-23 2021-04-01 Genzyme Corporation Product quality attribute measurement
JP7388206B2 (ja) * 2020-01-22 2023-11-29 株式会社島津製作所 液体クロマトグラフおよび分析方法
US11988647B2 (en) 2020-07-07 2024-05-21 Waters Technologies Corporation Combination mixer arrangement for noise reduction in liquid chromatography
WO2022010665A1 (en) 2020-07-07 2022-01-13 Waters Technologies Corporation Mixer for liquid chromatography
WO2022066752A1 (en) 2020-09-22 2022-03-31 Waters Technologies Corporation Continuous flow mixer
JP2022091322A (ja) * 2020-12-09 2022-06-21 株式会社島津製作所 液体クロマトグラフのｐＨ管理システムおよびプログラム
WO2023165947A1 (en) * 2022-03-03 2023-09-07 Chromacon Ag Chromatographic purification method and uses thereof
CN114797173A (zh) * 2022-04-10 2022-07-29 南通星中细胞工程有限公司 一种用于外泌体的高效制备装置及制备方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3918907A (en) * 1973-10-29 1975-11-11 Beckman Instruments Inc Micro automatic amino acid analysis process and system
US4246101A (en) * 1978-12-28 1981-01-20 Pure Cycle Corporation Water recycling system
US4762796A (en) 1981-10-05 1988-08-09 Exxon Research And Engineering Company pH control of a process stream
JPS62255865A (ja) 1986-04-28 1987-11-07 Hitachi Ltd 液体クロマトグラフ
US4840730A (en) * 1986-07-25 1989-06-20 Sepragen Corporation Chromatography system using horizontal flow columns
JP2581568B2 (ja) 1987-10-08 1997-02-12 株式会社日立製作所 イオンクロマトグラフイ装置
US5114576A (en) * 1990-02-15 1992-05-19 Trineos Prevention of contaminants buildup in captured and recirculated water systems
DE69216520T2 (de) * 1991-03-28 1997-04-24 Perseptive Biosystems Inc Produktinformation in chromatographischem effluenten durch differenzbildung
US5792371A (en) 1996-08-22 1998-08-11 Iosolutions Incorporated Method of disinfecting water with iodine species
US6799883B1 (en) 1999-12-20 2004-10-05 Air Liquide America L.P. Method for continuously blending chemical solutions
AU2002325755A1 (en) * 2001-09-18 2003-04-01 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
WO2003083467A2 (de) 2002-03-28 2003-10-09 Siemens Aktiengesellschaft Gaschromatograph und verfahren zur gaschromatographischen analyse eines stoffgemischs
JP2004077329A (ja) 2002-08-20 2004-03-11 Japan Organo Co Ltd クロマト分離装置
US6972415B2 (en) * 2002-09-26 2005-12-06 R-Can Environmental Inc. Fluid treatment system with UV sensor and intelligent driver
US20040124253A1 (en) * 2002-10-17 2004-07-01 Bergwin Gregory A. Injection apparatus for irrigation system
US20040102380A1 (en) 2002-11-18 2004-05-27 Fulton Scott P. Method for continuous, automated blending of solutions from acids and bases
WO2004103519A2 (en) * 2003-05-16 2004-12-02 Cryobiophysica, Inc. External gradient chromatofocusing
US7632410B2 (en) * 2003-08-21 2009-12-15 Christopher Heiss Universal water purification system
US8271139B2 (en) 2003-10-17 2012-09-18 Asahi Kasei Bioprocess, Inc. Multi-stage accurate blending system and method
WO2005040787A1 (en) 2003-10-17 2005-05-06 Ge Healthcare Bio-Sciences Ab Chromatography system, method and software for the separation of biomolecules
US7072742B1 (en) 2003-10-17 2006-07-04 Technikrom, Inc. Accurate blending module and method
EP1751537B1 (en) 2004-05-17 2019-07-10 Firmenich SA Multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface
GB2429785B (en) * 2004-05-21 2009-11-18 Waters Investments Ltd Closed loop flow control of a hplc constant flow pump to enable low-flow operation
US7642306B2 (en) 2004-06-25 2010-01-05 Johns Manville Control of pH in formaldehyde-free binder systems
WO2006039588A2 (en) 2004-09-30 2006-04-13 Bayer Healthcare Llc Devices and methods for integrated continuous manufacturing of biological molecules
EP2491993B1 (en) 2005-01-20 2018-10-03 Waters Technologies Corporation Methods for separating compounds
EP1716900A1 (en) 2005-04-29 2006-11-02 Eidgenössische Technische Hochschule Zürich Method and device for chromatographic purification
EP1775001A1 (en) 2005-10-13 2007-04-18 Xendo Holding B.V. Device for chromatographic separations
JP4939910B2 (ja) * 2006-11-29 2012-05-30 株式会社東芝 マイクロ化学分析システム及びマイクロ化学分析装置
US9012212B2 (en) 2007-04-17 2015-04-21 Xendo Holding B.V. Method and device for continuous membrane adsorption
GB0709109D0 (en) 2007-05-11 2007-06-20 Enpar Technologies Inc Wastewater ammonium extraction and electrolytic conversion to nitrogen gas
WO2009045897A1 (en) 2007-10-03 2009-04-09 Dyax Corp. Systems and methods for purifying proteins
CN103396480A (zh) 2008-05-15 2013-11-20 诺沃—诺迪斯克有限公司 抗体纯化方法
EP2421631B1 (en) 2009-04-23 2021-05-26 Global Life Sciences Solutions USA LLC Chromatography system and method with feedback control for variable speed loading

Also Published As

Publication number Publication date
EP2480305A4 (en) 2014-07-02
CN102574026A (zh) 2012-07-11
JP2013506127A (ja) 2013-02-21
AU2010298768A1 (en) 2012-03-15
WO2011037522A1 (en) 2011-03-31
EP2480305A1 (en) 2012-08-01
CN102574026B (zh) 2015-10-07
EP2480305B1 (en) 2020-10-28
US20110073548A1 (en) 2011-03-31
AU2010298768B2 (en) 2015-07-02
US9527010B2 (en) 2016-12-27
JP5749270B2 (ja) 2015-07-15

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