IN2012DN01850A - - Google Patents

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Publication number
IN2012DN01850A
IN2012DN01850A IN1850DEN2012A IN2012DN01850A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A IN 1850DEN2012 A IN1850DEN2012 A IN 1850DEN2012A IN 2012DN01850 A IN2012DN01850 A IN 2012DN01850A
Authority
IN
India
Prior art keywords
separation
line
units
fluid
separation unit
Prior art date
Application number
Other languages
English (en)
Inventor
M Williams Alan
Kaletski Adam
Stack Lisa
G Go Daniel
Krasnansky John
A Wareheim David
Lin Bin
Original Assignee
Ge Healthcare Bio Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43779133&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IN2012DN01850(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ge Healthcare Bio Sciences filed Critical Ge Healthcare Bio Sciences
Publication of IN2012DN01850A publication Critical patent/IN2012DN01850A/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
IN1850DEN2012 2009-09-25 2010-09-20 IN2012DN01850A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/566,701 US9527010B2 (en) 2009-09-25 2009-09-25 Separation system and method
PCT/SE2010/051003 WO2011037522A1 (en) 2009-09-25 2010-09-20 Separation system and method

Publications (1)

Publication Number Publication Date
IN2012DN01850A true IN2012DN01850A (zh) 2015-08-21

Family

ID=43779133

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1850DEN2012 IN2012DN01850A (zh) 2009-09-25 2010-09-20

Country Status (7)

Country Link
US (1) US9527010B2 (zh)
EP (1) EP2480305B1 (zh)
JP (1) JP5749270B2 (zh)
CN (1) CN102574026B (zh)
AU (1) AU2010298768B2 (zh)
IN (1) IN2012DN01850A (zh)
WO (1) WO2011037522A1 (zh)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5961112B2 (ja) * 2009-09-25 2016-08-02 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 液体混合物の調製方法及びシステム
MX2012009283A (es) * 2010-02-12 2012-09-07 Dsm Ip Assets Bv Purificacion de anticuerpo de una unidad.
WO2012014183A1 (en) * 2010-07-30 2012-02-02 Pfizer Inc. Tandem purification of proteins
EP2433952B1 (en) * 2010-09-20 2015-09-02 Asahi Kasei Bioprocess, Inc. Liquid chromatography system and method for protein separation and purification
US20130289247A1 (en) * 2010-11-01 2013-10-31 Dsm Ip Assets B.V. Single unit ion exchange chromatography antibody purification
US20140187749A1 (en) * 2011-06-16 2014-07-03 Dsm Ip Assets B.V. Single unit chromatography antibody purification
WO2013028330A2 (en) 2011-08-19 2013-02-28 Emd Millipore Corporation Methods of reducing level of one of more impurities in a sample during protein purification
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
CA2850581A1 (en) * 2011-11-10 2013-05-16 F. Hoffmann-La Roche Ag Preparative column chromatography system
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
ES2895173T3 (es) * 2012-06-29 2022-02-17 Emd Millipore Corp Métodos para inactivar virus durante un proceso de purificación de proteínas
DK3301115T3 (da) * 2013-05-06 2022-01-31 Sanofi Sa Kontinuerlig flertrinsfremgangsmåde til oprensning af antistoffer
CN104237418B (zh) * 2013-09-11 2015-11-18 青岛普仁仪器有限公司 免稀释作线性曲线的色谱仪及线性曲线测量方法
WO2015041218A1 (ja) * 2013-09-17 2015-03-26 株式会社カネカ 新規抗体精製方法及びそれから得られる抗体（Ｎｏｖｅｌ Ａｎｔｉｂｏｄｙ Ｐｕｒｉｆｉｃａｔｉｏｎ Ｍｅｔｈｏｄ ａｎｄ Ａｎｔｉｂｏｄｙ ｏｂｔａｉｎｅｄ ｔｈｅｒｅｆｒｏｍ）、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体（Ｎｏｖｅｌ Ａｎｔｉｂｏｄｙ Ｐｕｒｉｆｉｃａｔｉｏｎ ｍｅｔｈｏｄ ｕｓｉｎｇ Ｃａｔｉｏｎ Ｅｘｃｈａｎｇｅｒ ａｎｄ Ａｎｔｉｂｏｄｙ ｏｂｔａｉｎｅｄ ｔｈｅｒｅｆｒｏｍ）
ES2864721T3 (es) * 2014-02-07 2021-10-14 Cmc Biologics As Disposición y proceso continuo de un biorreactor para la producción y captura de un biopolímero
CN105980847B (zh) * 2014-02-14 2018-12-04 通用电气健康护理生物科学股份公司 自动多步纯化系统
JP6331485B2 (ja) * 2014-03-04 2018-05-30 株式会社島津製作所 液体クロマトグラフ及び液体クロマトグラフ分析方法
US20170058308A1 (en) * 2014-05-02 2017-03-02 Novo Nordisk A/S Integrated continuous biomanufacturing process
US11835501B2 (en) 2015-07-13 2023-12-05 Sartorius Stedim Chromatography Systems Ltd. Optimizing operating binding capacity for a multiple column chromatography process
JP6579515B2 (ja) * 2015-08-10 2019-09-25 国立大学法人 岡山大学 アポｅ含有ｈｄｌの測定方法及び測定装置
AU2017248025B2 (en) * 2016-04-04 2022-03-03 Boehringer Ingelheim Rcv Gmbh & Co Kg Real time monitoring of product purification
GB201622343D0 (en) * 2016-12-29 2017-02-15 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
WO2018140485A1 (en) * 2017-01-26 2018-08-02 Counsyl, Inc. Reagent delivery and waste management system
US11185830B2 (en) 2017-09-06 2021-11-30 Waters Technologies Corporation Fluid mixer
FR3073424B1 (fr) 2017-11-16 2022-03-25 Novasep Process Procede regule de separation d’un melange
GB201802593D0 (en) * 2018-02-16 2018-04-04 Fujifilm Diosynth Biotechnologies Uk Ltd Rig
CN111918873A (zh) * 2018-03-27 2020-11-10 百时美施贵宝公司 使用紫外线信号实时监测滴度
CN109453545A (zh) * 2018-12-20 2019-03-12 上海兆维科技发展有限公司 层析柱洗脱液的配液装置
EP3763429A1 (en) * 2019-07-08 2021-01-13 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
EP3693732A1 (en) * 2019-02-11 2020-08-12 Bayer Aktiengesellschaft Influencing a sequential chromatography in real-time
SG11202107699QA (en) * 2019-02-11 2021-08-30 Bayer Ag Influencing a sequential chromatography in real-time
EP3699697A1 (en) * 2019-02-25 2020-08-26 Bayer Aktiengesellschaft Automated simultaneous process control
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
US11555805B2 (en) 2019-08-12 2023-01-17 Waters Technologies Corporation Mixer for chromatography system
GB201911686D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying target substances
GB201911685D0 (en) * 2019-08-15 2019-10-02 Fujifilm Diosynth Biotechnologies Uk Ltd Process for purifying monoclonal antibodies
CN114729916A (zh) * 2019-09-23 2022-07-08 建新公司 产品品质属性测量
JP7388206B2 (ja) * 2020-01-22 2023-11-29 株式会社島津製作所 液体クロマトグラフおよび分析方法
CN116134312A (zh) 2020-07-07 2023-05-16 沃特世科技公司 液相色谱用混合器
WO2022010666A1 (en) 2020-07-07 2022-01-13 Waters Technologies Corporation Combination mixer arrangement for noise reduction in fluid chromatography
US11821882B2 (en) 2020-09-22 2023-11-21 Waters Technologies Corporation Continuous flow mixer
WO2023165947A1 (en) * 2022-03-03 2023-09-07 Chromacon Ag Chromatographic purification method and uses thereof

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3918907A (en) * 1973-10-29 1975-11-11 Beckman Instruments Inc Micro automatic amino acid analysis process and system
US4246101A (en) * 1978-12-28 1981-01-20 Pure Cycle Corporation Water recycling system
US4762796A (en) 1981-10-05 1988-08-09 Exxon Research And Engineering Company pH control of a process stream
JPS62255865A (ja) 1986-04-28 1987-11-07 Hitachi Ltd 液体クロマトグラフ
US4840730A (en) * 1986-07-25 1989-06-20 Sepragen Corporation Chromatography system using horizontal flow columns
JP2581568B2 (ja) 1987-10-08 1997-02-12 株式会社日立製作所 イオンクロマトグラフイ装置
US5114576A (en) * 1990-02-15 1992-05-19 Trineos Prevention of contaminants buildup in captured and recirculated water systems
DE69216520T2 (de) * 1991-03-28 1997-04-24 Perseptive Biosystems Inc Produktinformation in chromatographischem effluenten durch differenzbildung
US5792371A (en) 1996-08-22 1998-08-11 Iosolutions Incorporated Method of disinfecting water with iodine species
US6799883B1 (en) 1999-12-20 2004-10-05 Air Liquide America L.P. Method for continuously blending chemical solutions
WO2003025156A2 (en) * 2001-09-18 2003-03-27 Affinium Pharmaceuticals, Inc. Methods and apparatuses for purification
WO2003083467A2 (de) 2002-03-28 2003-10-09 Siemens Aktiengesellschaft Gaschromatograph und verfahren zur gaschromatographischen analyse eines stoffgemischs
JP2004077329A (ja) * 2002-08-20 2004-03-11 Japan Organo Co Ltd クロマト分離装置
US6972415B2 (en) * 2002-09-26 2005-12-06 R-Can Environmental Inc. Fluid treatment system with UV sensor and intelligent driver
US20040124253A1 (en) * 2002-10-17 2004-07-01 Bergwin Gregory A. Injection apparatus for irrigation system
EP1567659A4 (en) 2002-11-18 2006-08-09 Taurus Hsa Llc METHOD FOR AUTOMATED AND CONTINUOUS MIXING OF SOLUTIONS FROM ACIDS AND BASES
US7790025B2 (en) 2003-05-16 2010-09-07 Cryobiophysica, Inc. External gradient chromatofocusing
US7632410B2 (en) * 2003-08-21 2009-12-15 Christopher Heiss Universal water purification system
WO2005040787A1 (en) 2003-10-17 2005-05-06 Ge Healthcare Bio-Sciences Ab Chromatography system, method and software for the separation of biomolecules
US8271139B2 (en) 2003-10-17 2012-09-18 Asahi Kasei Bioprocess, Inc. Multi-stage accurate blending system and method
US7072742B1 (en) 2003-10-17 2006-07-04 Technikrom, Inc. Accurate blending module and method
AU2005242998B2 (en) * 2004-05-17 2010-05-27 Firmenich Sa New multidimensional gas chromatography apparatus and analyte transfer procedure using a multiple-cool strand interface
GB0624707D0 (en) * 2004-05-21 2007-01-17 Waters Investments Ltd Closed loop flow control of a hplc constant flow pump to enable low-flow operation
US7642306B2 (en) 2004-06-25 2010-01-05 Johns Manville Control of pH in formaldehyde-free binder systems
ES2634323T3 (es) 2004-09-30 2017-09-27 Bayer Healthcare Llc Dispositivos y procedimientos para la fabricación continua integrada de moléculas biológicas
EP3885018A1 (en) * 2005-01-20 2021-09-29 Waters Technologies Corporation Methods for separating compounds
EP1716900A1 (en) * 2005-04-29 2006-11-02 Eidgenössische Technische Hochschule Zürich Method and device for chromatographic purification
EP1775001A1 (en) 2005-10-13 2007-04-18 Xendo Holding B.V. Device for chromatographic separations
JP4939910B2 (ja) * 2006-11-29 2012-05-30 株式会社東芝 マイクロ化学分析システム及びマイクロ化学分析装置
DK2155347T3 (da) 2007-04-17 2013-10-21 Xendo Holding B V Fremgangsmåde og apparat til kontinuerlig membranadsorption
GB0709109D0 (en) 2007-05-11 2007-06-20 Enpar Technologies Inc Wastewater ammonium extraction and electrolytic conversion to nitrogen gas
US20090149638A1 (en) * 2007-10-03 2009-06-11 Ley Arthur C Systems and methods for purifying proteins
JP2011523408A (ja) 2008-05-15 2011-08-11 ノボ・ノルデイスク・エー／エス 抗体精製方法
WO2010124159A1 (en) 2009-04-23 2010-10-28 Xcellerex, Inc. System and method for variable speed feedback control chromatography loading

Also Published As

Publication number Publication date
EP2480305B1 (en) 2020-10-28
AU2010298768A1 (en) 2012-03-15
US9527010B2 (en) 2016-12-27
WO2011037522A1 (en) 2011-03-31
AU2010298768B2 (en) 2015-07-02
JP2013506127A (ja) 2013-02-21
CN102574026B (zh) 2015-10-07
JP5749270B2 (ja) 2015-07-15
CN102574026A (zh) 2012-07-11
EP2480305A4 (en) 2014-07-02
EP2480305A1 (en) 2012-08-01
US20110073548A1 (en) 2011-03-31

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