IN2012DN00899A - - Google Patents

Info

Publication number
IN2012DN00899A
IN2012DN00899A IN899DEN2012A IN2012DN00899A IN 2012DN00899 A IN2012DN00899 A IN 2012DN00899A IN 899DEN2012 A IN899DEN2012 A IN 899DEN2012A IN 2012DN00899 A IN2012DN00899 A IN 2012DN00899A
Authority
IN
India
Prior art keywords
culture system
cell culture
cell
continuous
less
Prior art date
Application number
Other languages
English (en)
Inventor
Grillberger Leopold
Reiter Manfred
Fleischanderl Daniel
Original Assignee
Baxter Healthcare Sa
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare Sa, Baxter Int filed Critical Baxter Healthcare Sa
Publication of IN2012DN00899A publication Critical patent/IN2012DN00899A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00Tissue, human, animal or plant cell, or virus culture apparatus
    • C12M3/006Cell injection or fusion devices
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0056Xeno-free medium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/98Xeno-free medium and culture conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/00051Methods of production or purification of viral material
    • C12N2710/00052Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24087ADAMTS13 endopeptidase (3.4.24.87)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
IN899DEN2012 2009-07-31 2010-08-02 IN2012DN00899A (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23031309P 2009-07-31 2009-07-31
PCT/EP2010/061191 WO2011012725A1 (en) 2009-07-31 2010-08-02 Method of producing a polypeptide or virus of interest in a continuous cell culture

Publications (1)

Publication Number Publication Date
IN2012DN00899A true IN2012DN00899A (el) 2015-04-03

Family

ID=42668436

Family Applications (1)

Application Number Title Priority Date Filing Date
IN899DEN2012 IN2012DN00899A (el) 2009-07-31 2010-08-02

Country Status (22)

Country Link
US (4) US8580554B2 (el)
EP (2) EP2459697B1 (el)
JP (2) JP5808742B2 (el)
KR (2) KR101752789B1 (el)
CN (1) CN102549142B (el)
AU (1) AU2010277490B2 (el)
BR (1) BR112012002137B8 (el)
CA (1) CA2769354A1 (el)
CO (1) CO6491119A2 (el)
DK (1) DK2459697T3 (el)
EA (1) EA022219B1 (el)
ES (1) ES2705206T3 (el)
HR (1) HRP20182165T1 (el)
IN (1) IN2012DN00899A (el)
MX (2) MX2012001274A (el)
NZ (1) NZ597742A (el)
PL (1) PL2459697T3 (el)
PT (1) PT2459697T (el)
SG (1) SG178176A1 (el)
SI (1) SI2459697T1 (el)
TR (1) TR201900213T4 (el)
WO (1) WO2011012725A1 (el)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201815211T4 (tr) 2010-07-08 2018-11-21 Baxalta GmbH Hücre kültüründe rekombinant adamts13 üretmeye yönelik yöntem.
DK3626737T3 (da) 2011-05-13 2024-02-05 Octapharma Ag Fremgangsmåde til at forøge produktiviteten af eukaryote celler i produktionen af rekombinant fviii
SI2837680T1 (sl) 2011-07-01 2020-07-31 Amgen Inc. Celična kultura sesalca
CN203129697U (zh) 2013-02-05 2013-08-14 客贝利(厦门)休闲用品有限公司 一种帐篷架杆
AU2012342355B2 (en) 2011-11-24 2017-10-12 Genethon Scalable lentiviral vector production system compatible with industrial pharmaceutical applications
US9574167B2 (en) 2013-02-15 2017-02-21 Pharyx, Inc. Methods and apparatus for independent control of product and reactant concentrations
WO2014137903A2 (en) 2013-03-08 2014-09-12 Genzyme Corporation Integrated continuous manufacturing of therapeutic protein drug substances
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
ES2842350T3 (es) * 2013-03-19 2021-07-13 Cmc Biologics As Un procedimiento para la producción de un producto (por ejemplo, polipéptido) en un proceso de fermentación de cultivo celular continuo
ES2778928T3 (es) * 2013-08-30 2020-08-12 Glaxosmithkline Biologicals Sa Producción a gran escala de virus en cultivos celulares
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
TWI709570B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析法及製法
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
MX2016012870A (es) 2014-04-01 2017-05-12 Advantech Bioscience Farmacêutica Ltda Formulaciones de factor viii estables con bajo tenor de azucar - glicina.
MX2016012869A (es) 2014-04-01 2017-05-12 Advantech Bioscience Farmacêutica Ltda Estabilizacion del factor viii sin calcio como un excipiente.
WO2015188224A1 (en) * 2014-06-13 2015-12-17 Csl Limited Improved production of recombinant von willebrand factor in a bioreactor
KR20180101596A (ko) * 2016-01-26 2018-09-12 베링거 인겔하임 인터내셔날 게엠베하 연결된 관류 대 연속-유동식 교반-탱크 반응기 세포 배양 시스템
KR102414290B1 (ko) * 2016-04-15 2022-06-29 베링거 인겔하임 인터내셔날 게엠베하 세포 보유 장치 및 방법
WO2018115161A1 (en) * 2016-12-21 2018-06-28 F. Hoffmann-La Roche Ag Growth control of eukaryotic cells
WO2019239780A1 (ja) * 2018-06-15 2019-12-19 富士フイルム株式会社 細胞培養方法、細胞培養装置、及び生産物の製造方法
KR20210049155A (ko) 2018-08-31 2021-05-04 젠자임 코포레이션 멸균 크로마토그래피 수지 및 제조 공정에서 이의 용도
CN113355297A (zh) * 2021-06-23 2021-09-07 吉林冠界生物技术有限公司 一种灌流式培养全悬浮mdck细胞生产重组禽流感病毒的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019512A (en) 1989-03-17 1991-05-28 Baxter International Inc. Spin filter for removing substantially cell-free culture medium from suspension cell culture system
US5626734A (en) 1995-08-18 1997-05-06 University Technologies International, Inc. Filter for perfusion cultures of animal cells and the like
BR0114374A (pt) 2000-10-02 2003-12-30 Novo Nordisk As Preparação compreendendo uma pluralidade de polipeptìdeos de fator vii, métodos para a determinação do padrão de glicoforma de fator vii e de polipeptìdeos relacionados com fator vii, e para a produção da dita preparação, formulação farmacêutica, métodos para o tratamento de uma sìndrome responsiva a fator vii, para a prevenção de sangramento indesejado, para a prevenção de coagulação sanguìnea indesejada, e para prevenção de reações mediadas por fator de tecido, e, uso da preparação
KR20040065231A (ko) * 2001-11-28 2004-07-21 산도즈 게엠베하 세포 배양 방법
TWI384069B (zh) 2004-08-27 2013-02-01 Pfizer Ireland Pharmaceuticals 多胜肽之製法
ATE544866T1 (de) 2005-06-17 2012-02-15 Baxter Int Adamts13-haltige zusammensetzungen mit thrombolytischer wirkung
EP2522717B1 (en) 2006-01-04 2014-04-02 Baxter International Inc Oligopeptide-free cell culture media
DK2235197T3 (en) * 2007-12-27 2017-10-09 Baxalta GmbH Methods of cell culture

Also Published As

Publication number Publication date
ES2705206T3 (es) 2019-03-22
EP2459697A1 (en) 2012-06-06
BR112012002137A2 (pt) 2015-09-15
KR20170077286A (ko) 2017-07-05
US20180051261A1 (en) 2018-02-22
US9650612B2 (en) 2017-05-16
HRP20182165T1 (hr) 2019-03-08
PL2459697T3 (pl) 2019-04-30
WO2011012725A8 (en) 2011-05-05
NZ597742A (en) 2014-02-28
MX2012001274A (es) 2012-06-01
EP2459697B1 (en) 2018-10-17
KR101885046B1 (ko) 2018-08-02
EA201270213A1 (ru) 2012-06-29
KR101752789B1 (ko) 2017-06-30
WO2011012725A1 (en) 2011-02-03
PT2459697T (pt) 2019-01-21
KR20120038531A (ko) 2012-04-23
JP6177260B2 (ja) 2017-08-09
AU2010277490A1 (en) 2012-02-09
EA022219B1 (ru) 2015-11-30
CN102549142A (zh) 2012-07-04
US10221400B2 (en) 2019-03-05
US20190153400A1 (en) 2019-05-23
BR112012002137B8 (pt) 2020-05-12
BR112012002137B1 (pt) 2020-04-14
EP3480292A1 (en) 2019-05-08
US8580554B2 (en) 2013-11-12
DK2459697T3 (en) 2019-01-28
AU2010277490B2 (en) 2014-08-28
TR201900213T4 (tr) 2019-02-21
MX353610B (es) 2018-01-18
CO6491119A2 (es) 2012-07-31
US20110086411A1 (en) 2011-04-14
JP5808742B2 (ja) 2015-11-10
JP2013500710A (ja) 2013-01-10
SG178176A1 (en) 2012-03-29
US10745672B2 (en) 2020-08-18
CN102549142B (zh) 2014-07-16
US20140038264A1 (en) 2014-02-06
CA2769354A1 (en) 2011-02-03
JP2015062436A (ja) 2015-04-09
SI2459697T1 (sl) 2019-03-29

Similar Documents

Publication Publication Date Title
IN2012DN00899A (el)
JP2016105737A5 (el)
JP2015521848A5 (el)
AU2019268194A1 (en) Cell culture system
NZ601424A (en) Method for the production of ad26 adenoviral vectors
NZ598677A (en) Production of proteins in glutamine-free cell culture media
NZ602958A (en) High level expression of recombinant toxin proteins
MX2012003654A (es) Metodos de produccion de glucoproteinas en cultivos de celulas de mamiferos usando glucocorticoides.
NZ593235A (en) Method for the production of recombinant adenovirus serotype 35
ATE488600T1 (de) Produktqualitätsverbesserung in säugerzellkulturverfahrenzur proteinproduktion
MX2009011805A (es) Mejora de las concentraciones de polipeptido del factor viii en cultivos celulares.
WO2001051616A3 (en) Techniques for growth and differentiation of human pluripotent stem cells
NZ586250A (en) Cell culture processes
MX353489B (es) Metodo para producir eritrocitos sin celulas alimentadoras.
NZ597334A (en) Cell culture improvements
WO2008090770A1 (ja) L-アミノ酸を生産する微生物及びl-アミノ酸の製造法
WO2007088372A3 (en) Cell culture
JP2013510570A5 (el)
MX2013005853A (es) Enzimas de fusion que tienen actividad de n-acetilglucosaminil transferasa.
WO2009016078A3 (en) Method for culturing mammalian stem cells
AR084998A1 (es) Metodo de fermentacion de un sustrato gaseoso que comprende hidrogeno
WO2011096750A3 (en) Method for preparing recombinant glycoproteins with high sialic acid content
BR112013028006A2 (pt) método para aumentar a produtividade de células eucarióticas na produção do recombinante fviii
MX2020013633A (es) Metodos para producir proteinas recombinantes.
WO2010115634A8 (en) Method for improved single cell cloning